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in children and young people: recognition, detection, risk profiling and NICE Pathways bring together everything NICE says on a topic in an interactive flowchart. NICE Pathways are interactive and designed to be used online. They are updated regularly as new NICE guidance is published. To view the latest version of this NICE Pathway see: http://pathways.nice.org.uk/pathways/depression NICE Pathway last updated: 24 April 2018 This document contains a single flowchart and uses numbering to link the boxes to the associated recommendations. Page 1 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways Page 2 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways 1 Child or young person at risk of depression No additional information 2 Recognition, detection, risk profiling and in tier 1 No additional information 3 Child or young person has acute sadness and distress ('situational dysphoria') Consider ongoing social and environmental factors if dysphoria becomes more persistent. 4 Child or young person exposed to a single recent undesirable life event Examples of a single recent undesirable life event include bereavement, parental divorce or separation, or a severely disappointing experience. 5 Assessment of risk of depression Assess the risks of depression associated with the event. Make contact with parent(s)/carer(s) to help integrate parental/carer and professional responses. Record the risk profile. 6 No other risk factors for depression If there are no other risk factors for depression: offer support and the opportunity to talk over the event do not normally refer for further assessment or treatment following an undesirable event. Page 3 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways 7 High risk of depression and/or family history If high risk of depression is identified (the presence of two or more other risk factors) and/or where one or more family members (parents or children) have multiple-risk histories: offer the opportunity to talk over recent negative experiences with a tier 1 professional assess for depression consider early if there is evidence of depression and/or self-harm. Also see assessment and treatment considerations. 8 Tier 1 and to tiers 2, 3 or 4 CAMHS Criteria for management to remain at tier 1 Management can remain at tier 1 if one or more of the following factors exist: exposure to a single undesirable event in the absence of other risk factors for depression exposure to a recent undesirable life event in the presence of two or more other risk factors with no evidence of depression and/or self-harm exposure to a recent undesirable life event where one or more family members (parents or children) have multiple-risk histories for depression, providing that there is no evidence of depression and/or self-harm in the child/young person mild depression without comorbidity. Referral to tier 2 or tier 3 Refer to tier 2 or tier 3 CAMHS if one or more of the following factors exist: depression with two or more other risk factors for depression depression where one or more family members (parents or children) have multiple-risk histories for depression mild depression in those who have not responded to interventions in tier 1 after 2 3 months moderate or severe depression (including psychotic depression) signs of a recurrence of depression in those who have recovered from previous moderate or severe depression unexplained self-neglect of at least 1 month's duration that could be harmful to the child/ young person's physical health Page 4 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways active suicidal ideas or plans young person or parent(s)/carer(s) request. Referral to tier 4 Refer to tier 4 CAMHS if one or more of the following factors exist: high recurrent risk of acts of self-harm or suicide significant ongoing self-neglect (such as poor personal hygiene or significant reduction in eating that could be harmful to physical health) requirement for intensity of assessment/treatment and/or level of supervision that is not available in tier 2 or 3. Quality standards The following quality statements are relevant to this part of the interactive flowchart. in children and young people 3. Suspected severe depression and at high risk of suicide 4. Suspected severe depression without high risk of suicide 9 Management of mild depression tiers 1 and 2 See / Management of mild depression in children and young people tiers 1 and 2 10 Management of moderate to severe (including psychotic) depression tiers 2 4 See / Management of moderate to severe (including psychotic) depression in children and young people tiers 2 4 11 Recognition in tiers 2 4 If a child or young person aged 11 years or older is referred to CAMHS without a diagnosis of depression, routinely screen with a self-report questionnaire for depression as part of general assessment. Page 5 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways Glossary CAMHS child and adolescent mental health services CAPA child and adolescent psychiatric assessment CBT cognitive behavioural therapy CCBT computerised cognitive behavioural therapy DSM-IV diagnostic and Statistical Manual of Mental Disorders ECT electroconvulsive therapy HoNOSCA Health of the Nation Outcome Scales for Children and Adolescents ICD-10 International Statistical Classification of Diseases and Related Health Problems (tenth edition) IPT interpersonal therapy K-SADS schedule for affective disorders and schizophrenia for school-age children Page 6 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways MAOI monoamine oxidase inhibitor MFQ mood and feelings questionnaire Mild depression few, if any, symptoms of depression in excess of the 5 required to make the diagnosis, and symptoms result in only minor functional impairment, according to DSM-IV Moderate depression symptoms of depression or functional impairment are between mild and severe NSAID non-steroidal anti-inflammatory drug SDQ strengths and difficulties questionnaire Severe depression most symptoms of depression according to DSM-IV, and the symptoms markedly interfere with functioning. Can occur with or without psychotic symptoms SSRI selective serotonin reuptake inhibitor Subthreshold depressive symptoms fewer than 5 symptoms according to DSM-IV TCA tricyclic antidepressant Page 7 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways Tier 1 primary care services including GPs, paediatricians, health visitors, school nurses, social workers, teachers, juvenile justice workers, voluntary agencies and social services Tier 2 child and adolescent mental health services relating to workers in primary care including clinical child psychologists, paediatricians with specialist training in mental health, educational psychologists, child and adolescent psychiatrists, child and adolescent psychotherapists, counsellors, community nurses/nurse specialists and family therapists Tier 3 specialised child and adolescent mental health services for more severe, complex or persistent disorders including child and adolescent psychiatrists, clinical child psychologists, nurses (community or inpatient), child and adolescent psychotherapists, occupational therapists, speech and language therapists, art, music and drama therapists, and family therapists Tier 4 tertiary-level child and adolescent mental health services such as day units, highly specialised outpatient teams and inpatient units Sources in children and young people: identification and management (2005 updated 2017) NICE guideline CG28 Your responsibility Guidelines The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual Page 8 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways needs, preferences and values of their patients or the people using their service. It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions appropriate to the circumstances of the individual, in consultation with them and their families and carers or guardian. Local commissioners and providers of healthcare have a responsibility to enable the guideline to be applied when individual professionals and people using services wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Technology appraisals The recommendations in this interactive flowchart represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to take these recommendations fully into account, alongside the individual needs, preferences and values of their patients. The application of the recommendations in this interactive flowchart is at the discretion of health professionals and their individual patients and do not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian. Commissioners and/or providers have a responsibility to provide the funding required to enable the recommendations to be applied when individual health professionals and their patients wish to use it, in accordance with the NHS Constitution. They should do so in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Page 9 of 10

in children and young people: recognition, detection, risk profiling and NICE Pathways Medical technologies guidance, diagnostics guidance and interventional procedures guidance The recommendations in this interactive flowchart represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take these recommendations fully into account. However, the interactive flowchart does not override the individual responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or guardian or carer. Commissioners and/or providers have a responsibility to implement the recommendations, in their local context, in light of their duties to have due regard to the need to eliminate unlawful discrimination, advance equality of opportunity, and foster good relations. Nothing in this interactive flowchart should be interpreted in a way that would be inconsistent with compliance with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Page 10 of 10