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2010 Advances IN Diabetes plus Nov. 10 Clinical Issues and Advances in Thyroid and Parathyroid Disease November 11 13, 2010 The Fairmont Copley Plaza Hotel Boston, MA Course Directors Martin J. Abrahamson, MD Chief Medical Officer Richard S. Beaser, MD Associate Clinical Professor of Medicine Medical Executive Director, Professional Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. designates this educational activity Advances in Diabetes for a maximum of 19 and this educational activity Thyroid Day for a maximum of 6.75 AMA PRA Category 1 Credit.s Physicians should only claim credit commensurate with the extent of their participation in the activity. Space is limited. Register today at

2010 Advances IN Diabetes Why You Should Attend Because the majority of people with diabetes are cared for by their primary care providers, PCPs need a comprehensive review and update on diabetes management to provide optimal care. This annual CME course, initiated more than century ago by Elliott P. Joslin, MD, in conjunction with Harvard Medical School, is the longest-running continuously offered academic course in diabetes in the United States and, likely, the world. The course has evolved with diabetes practice and research as well as the changing continuing education needs of the medical profession. For 2010, the course adopts a new format emphasizing participant interaction in smaller breakout sessions for a more dynamic learning experience. Topics Insulin Treatment of Type 2 Diabetes Lifestyle Aspects of Diabetes Treatment Prevention and Treatment of Kidney Disease Diabetes and the Heart Reducing Cardiovascular Risk Microvascular Complications And more Learning Objectives Upon completion of this activity, participants will be able to: Describe recent advances in the understanding of the pathophysiology of type 1 and type 2 diabetes, as well as comorbidities of these conditions Describe advances in research related to diabetes treatments that have translated into improved glucose control and quality of life for people living with this condition Identify specific changes that clinicians will make in their practices regarding care of people with diabetes and comorbidities based on updated knowledge of state-of-the-art treatment approaches List improvements in skills in caring for people with diabetes and related conditions based on participation in presentations/discussions of clinical case scenarios Implement therapeutic strategies to overcome clinical practice obstacles resulting from various issues and barriers to optimal diabetes management relative to specific populations/ ethnic groups Special benefits and features Special lectures on treatment goals, kidney disease, and diabetes and the heart Practical workshops on using insulin, noninsulin medications, and lifestyle changes to manage diabetes Thyroid Day symposium on November 10 Best practices for managing diabetes in special populations such as the elderly, pregnant women, different ethnic or cultural groups, and hospitalized patients In-depth morning and evening symposia on sleep apnea, obesity treatments, and hypogonadism and erectile dysfunction in diabetes Timely, practical updates on complications and comorbidities An opportunity to learn from and interact with nationally and internationally recognized experts chosen for their superior experience and knowledge Space is limited. Register today at

Agenda* Thursday, November 11, 2010 7:00 Registration and Continental Breakfast Diabetes Glucose Management 8:00 Welcome and Pretest 8:10 Special Lecture: Should Treatment Goals for Type 2 Diabetes Be Changed? Horton 9:00 Type 2 Diabetes and Cardiometabolic Syndrome Shoelson 9:45 The Burgeoning Epidemic of Obesity in the U.S. Hamdy 10:30 Break Practical Workshops 10:45 Simultaneous Workshops 1. Use of Insulin in Diabetes Beaser, Ghiloni, Shetty 2. Lifestyle Aspects of Diabetes Treatment Maryniuk, Phillips, Rizzotto 3. Noninsulin Treatment of Type 2 Diabetes Abrahamson, Blair, Matfin 12:15 Lunch (on your own) Cardiometabolic Risk Factors 1:15 Evaluating Cardiometabolic Risk: A Primer for the PCP Pinto 2:00 Treatment of Dyslipidemia: Achieving Recommended Goals Ganda 2:45 Break 3:00 Hypertension 2010: A Rational Approach to Therapy TBD 3:45 Cardiac Evaluation of Patients with Diabetes: When and How Cutlip 4:30 Posttest Day 1 4:45 Break and Exhibits Evening Symposium 6:00 9:00 FRIDAY, November 12, 2010 Morning Symposium 6:00 7:30 Diabetes Complications 8:00 Pretest 8:10 Special Lecture: Treatment of Cardiovascular Disease in Patients with Diabetes Aroesty 9:00 Evaluation and Management of Diabetic Neuropathy Gibbons 9:45 Advances in Diabetic Retinopathy: Diagnosis, Treatment, and Prevention Sun 10:30 Break Practical Workshops 10:45 Simultaneous Workshops 1. Use of Insulin in Diabetes Beaser, O Donnell 2. Lifestyle Aspects of Diabetes Treatment Maryniuk, Rizzotto 3. Noninsulin Treatment of Type 2 Diabetes Abrahamson, Blair, Mitzner 12:15 Lunch JPEC PI CME Beaser, J. Brown, Neighbours Special Populations 1:15 Osteoporosis in Women with Diabetes: Balancing the Clinical Concerns Rosen 2:00 Hospital Care of Patients with Diabetes: A Systems-Based Perspective Mitzner 2:45 Break 3:00 Diversity and Diabetes: Optimizing Clinical Impact Caballero 3:45 Treating Diabetes in Older Adults: Achieving the Optimal Balance Munshi 4:30 Diabetes in Children and Adolescents: Challenges and Solutions Laffel 5:15 Posttest Day 2 5:30 Break and Exhibits Evening Symposium 7:00 9:00 SATURDAY, November 13, 2010 7:00 Continental Breakfast Diabetes Complications (continued) 8:00 Pretest 8:10 Special Lecture: Prevention and Treatment of Kidney Disease Stanton 9:00 Foot Care in People with Diabetes: Prevention and Early Intervention Giurini 9:45 Peripheral Vascular Disease and the Person with Diabetes: Cutting-Edge Approaches Campbell 10:30 Break Diabetes Clinical Care 10:45 Gestational Diabetes, Pregnancy, and Metabolic Care: Overlapping Concerns F. Brown 11:30 The Role of the Liver in Diabetes and Metabolic Disease: Clinical Perspectives Afdhal 12:15 Motivational Interviewing TBD 1:00 Posttest Day 3 1:15 Closing Remarks * Program changes/substitutions may be made without notice Accreditation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. designates the 2.5-day diabetes educational activity for a maximum of 19 AMA PRA Category 1 Credits. Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Medical Association has determined that physicians not licensed in the U.S. who participate in the CME activity are eligible for AMA PRA Category 1 Credit(s). Participants not eligible for continuing medical education credit will receive a certificate of participation.

Faculty* Martin J. Abrahamson, MD Medical Director and Senior Vice President JULIAN M. AROESTY, MD Associate Clinical Professor of Medicine Staff Physician, Cardiology RICHARD S. BEASER, MD Associate Clinical Professor of Medicine Medical Executive Director Professional Education Florence M. Brown, MD Co-Director, Diabetes and Pregnancy Program Enrique Caballero, MD Director, Medical Affairs Professional Education Director, Latino Diabetes Initiative David r. campbell Associate Clinic Professor of Surgery Vascular Surgeon DONALD E. CUTLIP, MD Director, Cardic Catheterization Laboratory Executive Director, Clinical Trials Harvard Clinical Research Institute Om P. Ganda, MD Associate Clinical Professor of Medicine Director, Lipid Clinic Suzanne Ghiloni, RN, BSN, CDE Diabetes Nurse Educator CHRISTOPHER H. gibbons, MD, MMSc Assistant Professor of Neurology, Staff Physician, Director, Neuropathy Clinic John M. Giurini, DPM Associate Professor in Surgery Chief, Division of Podiatry Osama Hamdy, MD, PhD, FACE Medical Director Obesity Clinical Program Edward S. Horton, MD Professor of Medicine, Senior Investigator Lori Laffel, MD, MPH Associate Professor of Pediatrics Chief, Pediatric, Adolescent and Young Adult Section Investigator, Genetics and Epidemiology Section MELINDA MARYNIUK, MEd, Rd, CDE Director Clinical Education Programs Strategic Initiatives Glenn Matfin, MSc (oxford), MB chb, FACE, FACP, FRCP Senior Physician LYLE D. MITZNER, Md Instructor in Medicine Attending Physician in Endocrinology Staff Physician Medha Munshi, MD, Director of Joslin Geriatric Diabetes Programs, Stacey O Donnell, RN, BSN, CDE Nurse Manager Adult Diabetes Nurse Educator Insulin Pump Specialist Edward M. Phillips, MD Assistant Professor of Physical Medicine and Rehabilitation Director, Outpatient Medical Services Spaulding Rehabilitation Hospital Network Assistant Physiatrist Massachusetts General Hospital Duane S. Pinto, MD, FACC Director, Cardiology Fellowship Training Program Jo-Anne Rizzotto, Md, RD, LDN, CDE Director of Educational Services HAROLD N. ROSEN, MD Staff Physician, Endocrinology Greeshma K. Shetty, MD Instructor in Medicine STEVEN E. SHOELSON, MD, PhD Professor of Medicine Section Head, Cellular and Molecular Physiology Robert C. Stanton, MD Chief of Nephrology JENNIFER K. SUN, MD, MPH Opthamologist Beetham Eye Institute Investigator, Eye Research *Subject to change

Clinical Issues and Advances in Thyroid and Parathyroid Disease Learning objectives Upon completion of this activity, participants will be able to: Describe the signs and symptoms of various types of thyroid diseases and abnormalities that would be an indication for further medical evaluation Discuss the interpretation of the results of thyroid function tests and images and how these results would be indications for further evaluation and/or therapeutic interventions Describe the usual course of treatments for the various of thyroid conditions and diseases discussed so as to effectively and efficiently monitor treatments and/or coordinate therapy with consultative specialty providers Accreditation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. designates the Thyroid Day educational activity for a maximum of 6.75 AMA PRA Category 1 Credits. Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Medical Association has determined that physicians not licensed in the U.S. who participate in the CME activity are eligible for AMA PRA Category 1 Credit(s). Participants not eligible for continuing medical education credit will receive a certificate of participation. Faculty* Agenda* Wednesday, NovEMBER 10, 2010 7:45 AM Welcome 8:00 Hypothyroidism 2010: Guidelines for Diagnosis, Confirmation, and Therapeutic Targets Garber 9:00 Hyperthyroidism Detection, Evaluation, and Intervention Hartzband 10:00 Break 10:30 Hyperparathyroidism: When to Suspect, How to Diagnose, When and How to Intervene Pallotta 11:30 Panel Discussion Garber, Hartzband, Pallotta 12:00 PM Lunch (on your own) 1:00 Thyroid Nodules: A Guidelines-Based Approach to Evaluation and Treatment Hennessey 2:00 Pediatric Thyroid Disease and the Primary Care Physician R. Brown 3:00 Break 3:30 Interactive Thyroid Cases: Putting Together Lessons Learned Hollenberg 4:00 Panel Discussion Hennessey, R. Brown, Hollenberg 4:45 Adjourn *Agenda and faculty subject to change Rosalind S. Brown, MD Associate Professor of Pediatrics Director, Clinical Trials Research Division of Endocrinology Children s Hospital Boston Pamela Hartzband, MD Medical Director, Thyroid Nodule Clinic Division of Endocrinology Anthony Hollenberg, MD Chief, Thyroid Unit Jeffrey R. Garber, MD, FACP, FACE Associate Professor Chief of Endocrinology Harvard Vanguard Medical Associates Immediate Past President American Association of Clinical Endocrinologists James V. Hennessey, MD Course director Director, Clinical Endocrinology Division of Endocrinology Johanna A. Pallotta, MD, FACP, FACE Senior Physician Space is limited. Register by September 25 and SAVE!

Online Information To register or view course information online, visit: Refund Policy A handling fee of $60 is deducted for cancellation. Refund requests must be received by mail one week prior to the course. No refunds will be made thereafter. Accommodations The Fairmont Copley Plaza Hotel 138 Saint James Avenue Boston, MA The Fairmont Copley Plaza Hotel Hotel rooms in Boston are limited. You are urged to make your reservations early to secure a reduced rate. A limited number of rooms have been reserved at the Fairmont Copley Plaza (telephone: 1-800-441-1414) until October 14, 2010. After October 14, contact Lani Paterson at 617-867-8506 for room availability. Please specify that you are enrolled in this course to receive a reduced room rate of $259 per night Standard Single/Double. Travel Please do not make nonrefundable airline reservations until you have been confirmed into your course. You can make your airline reservation by calling the HMS Travel Desk toll-free 1-877-4HARVMD (1-877-442-7863) Monday Friday, 9 am 8 pm (ET). From outside the U.S., Canada, and Virgin Islands, please call 1-617-559-3764. What your colleagues are saying about Advances in Diabetes The course was a clear, concise, yet detailed summary of the advances made in diabetes in the last decade. I wish that I had taken the course sooner. The faculty were excellent...loved the ARS...adds some interest to courses. Everything was excellent! Best course I have ever attended in my 25 years experience as a diabetes educator! Absolutely phenomenal job by all! The case presentations/panel discussions were very helpful in putting the lectures into perspective. Really enjoyed the case-based presentations, interaction between advances in science and practical management of diabetes. You succeeded in bringing diabetes research and treatment up to date, including about-to-be-published work. Speakers were very accomplished and knowledgeable. I am in a setting where we are steeped in diabetes education, practice, and research and was very pleasantly surprised by the quality and usefulness of the majority of the presentations. It was a comprehensive course, all aspects in the care of diabetes were covered, from top to bottom, and the speakers were knowlegeable and experts in their field. I really liked the case presentations. This was the most oustanding, comprehensive and well-organized course I have attended this year. Copyright 2010 by. All rights reserved.

Registration Information Attendance is limited register early! All foreign payments must be made by a draft on a United States bank or by Visa or MasterCard. If paying by credit card (MasterCard or Visa only), please register online at If paying by check, please make it payable to and mail, with completed registration form, to: -DCE P.O. Box 825 Boston, MA 02117-0825 Telephone or mail-in registration with credit card payment is not accepted. Inquiries should be directed to the above address, made by phone: (617) 384-8600, Monday Friday, 10 AM to 4 PM (ET), or by email: hms-cme@hms.harvard.edu. Upon receipt of your registration form, the HMS-DCE office will send an email confirmation to you. Therefore, be sure to include an email address that you check frequently. Your email address is used for critical information about the course including registration confirmation, course evaluation, and certificate. Tuition Fee Physicians Early Bird (by 9/25/10) After 9/25/10 Advances in Diabetes $595 $695 with Thyroid Day Advances in Diabetes only $525 $625 Thyroid Day only $195 $295 Residents* Fellows in Training* Allied Health Professionals Advances in Diabetes $495 $595 with Thyroid Day Advances in Diabetes only $415 $515 Thyroid Day only $145 $195 *With a letter of verification from the Department Chair Nonclinical Professionals Advances in Diabetes $995 $1,095 with Thyroid Day Advances in Diabetes only $895 $995 Thyroid Day Only $695 $795 Registration Form Nov. 11 13, 2010 Thyroid Day Nov. 10 Advances in Diabetes and Clinical Issues and Advances in Thyroid and Parathyroid Disease Class ID #03014077 Please check the course(s) you wish to attend: Both Advances in Diabetes & Thyroid Day November 10 13, 2010 Advances in Diabetes only November 11 13, 2010 Thyroid Day only November 10, 2010 Please check the type of registration: Physician Resident,* Fellow in Training,* Allied Health Professional Nonclinical Professional * Registration must be accompanied by a letter of verification from the Department Chair to receive discount. In compliance with the Americans with Disabilities Act, Joslin Diabetes Center will make every reasonable effort to accommodate your needs during your attendance at this activity. For any special requests, please contact at 888-567-5460. One registrant per form, please you may photocopy the form for others. All fields required. Name Degree Organization/Affiliation Primary Specialty (physicians only) Address City State Zip/Postal Code Country Telephone Fax Please Note: Your email address is used for critical information about the course including; registration, course evaluation and certification. Please be sure to include an email address that you check daily or frequently Email Please check if you want to be EXCLUDED from receiving email notices of future HMS-DCE programs. ID# (from address label) Check amount $ Mail to: HMS-DCE P.O. Box 825 Boston, MA 02117-0825 Accompany registration form with full payment. If paying by credit card, please register online at www.cme.hms.harvard.edu/courses/joslin. Telephone or mail-in registration with credit card payment is not accepted. Required

P.O. Box 825 Boston, MA 02117-0825 www.cme.hms.harvard.edu Presorted First Class Mail U.S. Postage PAID Permit 160 Stoughton, MA 2010 Advances IN Diabetes A CME activity addressing practical aspects of diabetes care and management, including the use of new technologies that address the growing complexity of care and the challenges of managing chronic illness in a primary care practice. plus New format emphasizes participant interaction for a more dynamic learning experience Nov. 10 Clinical Issues and Advances in Thyroid and Parathyroid Disease November 11 13, 2010 The Fairmont Copley Plaza Hotel Boston, MA Space is limited. Register today at