An overview of Extracorporeal shock wave lithotripsy (ESWL) and the role of Radiographers in ESWL. Tse Ka Wai, Sam (Rad II, TMH)

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An overview of Extracorporeal shock wave lithotripsy (ESWL) and the role of Radiographers in ESWL Tse Ka Wai, Sam (Rad II, TMH)

What is ESWL? ESWL Machine Body Stone

Renal Stone Incidence rate in HK population From a questionnaire survey done in 2008, ~2.5% population have renal stone Commonest age group: 50-59 years (worldwide) Usually Male more than Female in ratio 3:1 (worldwide)

Renal Stone (Nephrolithiasis) Crystallization of minerals inside urine, which act as the nidus for more sedimentation and finally the formation of a stone within the kidney.

Types of Kidney Stones (mentioned in the IVU tutorial) Calcium-containing stone (Radiopaque) Calcium Oxalate Calcium Phosphate Uric acid stone (Radiolucent) Cysteine stones (Light Radiopaque)

Signs and Symptoms of renal stone NO symptom Pain: sudden or severe pain, nausea, vomiting Renal colic Frequent and painful urination, hematuria Urinary tract infection: Block the urinary tract

Diagnosis Abdominal X-ray Intravenous Urogram (IVU) Ultrasound CT

CT Plain X-ray http://zh.wikipedia.org/w/index.php?title=image:kub_stone.jpg&variant=zh-tw http://www.medison.ru/uzi/img/p287.jpg Ultrasound

Treatment (Small Stones) For Stone < 5mm : Drink more water ->help to flush the stone out Medicine (e.g. calcium channel/alphablockers) No progress -> other treatments

Treatments ESWL Percutaneous nephrolithotomy (PCNL) Ureteroscopy (URS) / URSL Open surgery **Depend on size, number, location, kind of stone and patient type.

ESWL Indication Stones of less than 2 cm in the kidney or Stones of less than 1 cm in the ureter (usually proximal ureteric stone) Why?

Contra-indication Relevant coagulation problems Lung tissue in shock wave path Tumors in shock wave area Aneurysms Polyarthritis (difficult to positioning) Active pyelonephritis Pregnancy Relative contraindication: Untreated hypertension

What is ESWL? Use focusing Shock Waves to breakdown a stone into small pieces. Shock waves are acoustic pulses. Pass through better in water and solid but not in air. Introduce in 1980 by Dornier which is a supersonic aircraft company

Early ESWL Dornier HM-3 Placed in water tank http://www.mwstone.com/stones/equipment.htm

Nowadays ESWL

Basic Components of lithotripsy machine 1) A shockwave generator 2) A focusing system 3) A coupling system 4) An imaging/localization units

Shockwave generator and focusing system (TMS) F1: shockwave generator F2: Target (Stone) http://www.tmsuro.com/eng/physicians/swl/1a_vision_device.htm The shockwave is generated by electromagnetic generator.

Coupling system Provide a air-free contact In the propagation and transmission of a wave, energy is lost at interfaces with differing densities. A coupling system is needed to minimize the dissipation of energy of a shockwave as it traverses the skin surface

Coupling system TMS Dornier

Imaging units Fluoroscopy Ultrasound

The fracture mechanism of stone in ESWL Several models of mechanism were discussed in different articles Fragmentation need stress and strain ESWL pulse create pressure gradient to the stone Thus, resulting in stress and strain within the stone Effective when focus diameter is small than the stone. **The mechanisms of stone fragmentation is ESWL

Focal dimension Focal dimension is depends on the energy level. The higher energy level the larger the focal dimension. The focal dimension of around 3mm to 6mm

Video In vitro experiment of ESWL http://www.youtube.com/watch?v=huyr7 ktym7q Ureteral Stone under ESWL http://www.youtube.com/watch?v=l6uen FVo-oM

ESWL procedures

Preparation 1) Check preliminary KUB to find out the location of stone 2) Fasting 3) Take the blood pressure 4) Check the cardiac physical exam result to ensure patient s physical condition suit for exam (done by nurse) 5) Pre-medication (pain relief) by nurse 6) Check LMP for female patients 7) Brief the details of the treatment to the patient **

Patient co-operation is important! The feeling during the treatment (What is the feeling?) Shallow breathing (Why?) Any uncomfortable after positioning? Keep the posture for ~1 hour Raise out concern

Procedures 1) Lie the patient on the table (Supine oblique or prone?) Avoid the shockwave path pass through spine and pelvis!!! (Why?)

Procedures (localization using floro) 1) Compare with the previous KUB image 2) Using LCM, iliac crest and the spine as landmark 3) Move the patient in the mid level of the removable broad

Procedures (localization using floro) 4) Remove the broad 5) Screening in PA view (optional) 6) Apply gel to the coupling cushion 7) Move the coupling cushion to treatment position 8) Increase the coupling pressure and touch the patient skin 9) Apply soft pad or sand bag on the opposite side of the patient (immobilize the patient)

Procedures (localization using floro) 10) Screening in PA view 11) Move the table to locate the stone in the center 12) Screening in CC view

Procedures (localization using floro) 13) Adjust the height of the table to locate the stone in center 14) Instruct to the patient 15) Call doctor to confirm the position and start the treatment

Procedures (localization using US) **Renal stone only, Why? 1)Apply gel to coupling and attach to the patient skin 2) Position the ultrasound transducer on the patient in the longitudinal section

Procedures (localization using US) 3)Move the table in green arrow plane

Procedures (localization using US) 4) Move the table in green arrow plane 5) Center the stone in target

Procedures (localization using US) 6) Turn the transducer 90 degree and scan in transverse plane

Procedures (localization using US) 7) Instruct to the patient 8) Call doctor to confirm the position and start the treatment

During the treatment Select the suitable parameters 1) Power of shockwave (start from low energy level to high energy level) 2) The frequency of shockwave (ECG gated for patients with cardiac pacemakers or those with arrhythmias who regularly take anti-arrythmic drugs 3) Total energy of shockwave (Renal stone < Ureteric stone) High energy level + high frequency = shorter treatment time Low energy level + low frequency =longer treatment time

During the treatment Monitor the patient condition (e.g. Blood pressure, heart rate, pain) Any abnormality => Stop shock wave! Monitor the position and the progress of stone (floro or US) Move far away from the center => Stop shock wave and make adjustment!

Before ESWL After ESWL

Post Treatment Patient is being observed for at least an hour in Day ward. Follow up 2 weeks later with X-ray (KUB) Remaining Stone => ESWL again Other treatment

Complications Hematomas Risk of hemorrhage Hyperventilation tetany Blockage of urinary tract The higher the total energy, the higher risk

Advantages Non-invasive Safe No General anaesthesia Short treatment time Convenience

Disadvantages May require repeat procedures Not suitable for all types of stones Cause complications Painful

Reference 1) Presentation powerpoint by Beatrice Pang and Connie Li, 2011 2) Dornier Medtech. Operating Manual of Dornier Gemini. 2012 3) JS Rodman et al. No more kidney stones. 2007 4) SWH Chan et al. A report on randomly sampled questionnaire survey about renal stone disease in Hong Kong. HK Med J. 2008 5) B Sturtevant et al. Fracture mechanics model of stone comminution in ESWL and implications for tissue damage. Phys Med Biol. 2000 6) W Eisenmenger. The mechanisms of stone fragmentation in ESWL. Ultrasound in Med. & Biol. 2001 7) http://zh.wikipedia.org/w/index.php?title=image:kub_stone.j pg&variant=zh-tw 8) http://www.medison.ru/uzi/img/p287.jpg 9) http://www.mwstone.com/stones/equipment.htm 10) http://www.tms-uro.com/eng/physicians/swl/1a_vision_device.htm 11) http://www.dornier.com/emea/clinicalsolutions/urology/kidney-stones/ 12) http://emedicine.medscape.com/article/444554-overview

Questions

Question 1 What size of renal stone can be treat by ESWL? a. <5mm b. 5mm to 2cm c. >2cm Answer: B

Question 2 What is the sequence of priority to treat following stones? 1. Renal Stone (upper pole) 2. Renal Stone (lower pole) 3. Ureteric Stone (above iliac crest) 4. Ureteric Stone (below iliac crest) a) 1>2>3>4 b) 4>3>2>1 c) 3>4>1>2 d) 2>1>4>3 Answer : B

Question 3 Which stone require prone position during ESWL? a) Renal Stone (upper pole) b) Renal Stone (lower pole) c) Ureteric Stone (above iliac crest) d) Ureteric Stone (below iliac crest) Answer: D

Question 4 Which following components are important in ESWL? 1) A shockwave generator 2) A focusing system 3) A coupling system 4) An imaging/localization units a) 1, 2, 3 b) 1, 3, 4 c) 2, 3, 4 d) All of above Answer: D

Question 5 Which of following stones are not suitable for US localization? 1) Renal Stone (upper pole) 2) Renal Stone (lower pole) 3) Ureteric Stone (above iliac crest) 4) Ureteric Stone (below iliac crest) a) 1, 2 b) 1, 3 c) 2, 3 d) 3, 4 Answer : D

Question 6 Which are the advantages of US localization? 1) No ionizing radiation 2) Continuous monitoring of stone positioning 3) Operator dependent 4) Suitable for all renal stones a) 1, 2 b) 1, 2, 3 c) 1, 2, 4 d) All of above Answer : C

Question 7 During the treatment, patient is complaint of severe pain. What will you do? a) Use X ray to check to stone b) Call nurse to communicate to the patient c) Call doctor to communicate to the patient d) Stop shock wave Answer : D

Question 8 During the treatment(only use floro, No US), the stone is no longer seen under screening after 80% of total energy was delivered. What will you do? a) Stop shock wave b) Keep treatment until the total target energy c) Consult doctor Answer: B

Question 9 During the treatment, the patient is moved. You stop the shock wave and try to localize the stone again, but u can t find it. What will you do? a) Continue the treatment b) Using the previous screening images to help in re-localize the position c) Consult doctor to end the treatment Answer: C

Acknowledgement Ms Connie Li (PPT 2011) Ms Beatrice Pang (PPT 2011) Ms Gwendo Yiu Lithotripsy center in Ward C1, TMH