The Overarching of Pressure Injuries: The 3 legged stool - Wound Care

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The Overarching of Pressure Injuries: The 3 legged stool - Wound Care Barbara Delmore PhD RN CWCN MAPWCA IIWCC-NYU NPUAP 2017 Biennial Conference, New Orleans March 10, 2017 2017 National Pressure Ulcer Advisory Panel www.npuap.org Objectives Participants will: Define the principles of wound healing Describe the importance of wound bed preparation before treating a pressure injury 2 1

Successful Wound Healing Need a Plan Systematic wound bed preparation approach to address: Underlying causes of a wound Patient-centered concerns & care Reality of healing Encourages: Treating wounds with an EVB & interprofessional approach 3 Sibbald & colleagues. Wound Bed Preparation 2014 Update. Advances in Skin & Wound Care March 2014 Wound Bed Preparation Identify/Prevent/ Treat the Cause Person with a Pressure Injury Local wound care (Healable, maintenance, non-healable) Patient/Family Centered Concerns R.G. Sibbald, E.A. Ayello and H. Smart 2014 Debridement Inflammation/ Infection Moisture Balance 4 Edge Effect Sibbald & colleagues. ASWC. 2011 & 2014 2

What caused this pressure injury? Because..For successful healing or preventing recurrence, the cause has to be corrected 5 6 Identify/Prevent/Treat the Cause Consider--- Comprehensive wound assessment Blood flow adequate? What are the co-morbidities/co-factors Nutrition? Glycemic control? Medications? Smoking? Pain? Pressure/Shear!!!! Identify/Prevent/ Treat the Cause 3

Case Exemplar NYULMC 2014 98 year-old female Admitted to hospital for pneumonia, anorexia, & dehydration Bedbound Unstageable pressure injury on admission 7 Wound Bed Preparation Identify/Prevent/ Treat the Cause Person with a Wound Local wound care (Healable, maintenance, non-healable) R.G. Sibbald, E.A. Ayello and H. Smart 2014 Patient/Family Centered Concerns Debridement Inflammation/ Infection Moisture Balance 8 Edge Effect Sibbald & colleagues. ASWC. 2011 & 2014 4

Family wants everything done for the patient. NYULMC 2014 Sibbald & colleagues, Advances in Skin & Wound Care, 2011 & 2014 9 Patient/Family Centered Concerns Interprofessional approach Referrals as needed Individualize care Support systems Environmental factors Patient/Family Centered Concerns 10 5

Wound Bed Preparation Person with a Wound R.G. Sibbald, E.A. Ayello and H. Smart 2014 Identify/Prevent/ Treat the Cause Patient/Family Centered Concerns Local wound care (Healable, maintenance, non-healable) Debridement Inflammation/ Infection Moisture Balance 11 Edge Effect Sibbald & colleagues. ASWC. 2011 & 2014 Reality of Wound Healing Healable Wound Underlying cause can be corrected + adequate blood supply to heal 12 6

13 Reality of Wound Healing Maintenance Wounds The cause can be corrected- but: Clinical impediment Debridement Smoking cessation Glycemic control Lack of adherence System resources Addressing social/financial situation Reality of Wound Healing Non-healable Inadequate systemic or local factors for healing 14 7

Case Exemplar Patient/Family Centered Care Family discussions: Patient not a flap candidate NYULMC 2014 15 Wound Bed Preparation Identify/Prevent/ Treat the Cause Person with a Wound Local wound care (Healable, maintenance, non-healable) R.G. Sibbald, E.A. Ayello and H. Smart 2014 Patient/Family Centered Concerns Debridement Inflammation/ Infection Moisture Balance 16 Edge Effect Sibbald & colleagues. ASWC. 2011 & 2014 8

Case Exemplar Family plan Take patient home & heal wound with dressing changes Surgeon plan Debrided wound at bedside NYULMC 2014 17 Topicals- Maintenance Wounds Impaired capacity to heal Address wound characteristics & maintenance wound situation Consider topicals to control bacteria but preserve cells (non-cytotoxic) Antimicrobials, absorbent dressings, selective enzymatic debrider 18 Sibbald et al., 2011, 2014 9

Topicals Nonhealable Wounds No capacity to heal Address wound characteristics & patient/family centered concerns Consider topicals to control bacteria Cytotoxicity is less important Providone Iodine, odor control, high absorbency dressings, medical grade honey 19 Case Exemplar Endpoint Given rapid decline while in hospital, focus became end-of-life care Patient expired while in hospital NYULMC 2014 20 10

NUTRITION 3/14/2017 Objectives Re-visited Participants have: Defined the principles of wound healing Described the importance of wound bed preparation before treating a pressure injury 21 Treatment of Pressure Injuries The 3-Legged Stool Dr. Nancy Munoz DCN, MHA, RDN, FAND 22 11

Disclosures Nancy Munoz No financial disclosures 23 Learning Objectives Understand the impact of malnutrition on risk for pressure injury development and treatment Define the National Pressure Ulcer Advisory Panel (NPUAP) Nutrition Clinical Practice Guideline for the prevention and treatment of pressure injury Implement appropriate nutrition interventions for the prevention and treatment of pressure injuries 24 12

2017 National Pressure Ulcer Advisory Panel www.npuap.org Nutrition and Health Nutrition Determinant of health Promotes physiological wellbeing Also contributes to social, cultural, and psychological quality of life Promotes functionality Effective disease management approach Lessens chronic disease risk, slows disease progression, and reduces disease symptoms Risk for developing pressure injuries Treatment of pressure injury 26 13

Nutrition and Health To promote health Meet macronutrient needs Protein Carbohydrates Fat Ensure Micronutrient are provided in sufficient amount to sustain body functions Vitamins Minerals Eat Nutrients Not Numbers 27 Malnutrition 2017 National Pressure Ulcer Advisory Panel www.npuap.org 14

What is the nutrition status of our patients? Hospital Inpatients Protein-calorie malnutrition was the most common type of malnutrition In 2013, there were 1.95 million hospital stays that involved malnutrition 1.25 million malnutrition-related stays (63.9%) were categorized as protein-calorie malnutrition 21.6%- malnourished due to weight loss or failure to thrive 29 Reference: Statistical Brief #210. Healthcare Cost and Utilization Project (HCUP). September 2016. Agency for Healthcare Research and Quality, Rockville, MD. www.hcup-us.ahrq.gov/reports/statbriefs/sb210-malnutrition- Hospital-Stays-2013.jsp. What is the nutrition status of our patients? Other malnutrition related hospital stay types: 8.3% cachexia 4.4% underweight 1.7% postsurgical non-absorption 1% nutritional neglect Reference: Statistical Brief #210. Healthcare Cost and Utilization Project (HCUP). September 2016. Agency for Healthcare Research and Quality, Rockville, MD. www.hcup-us.ahrq.gov/reports/statbriefs/sb210-malnutrition-hospital-stays-2013.jsp. 30 15

Cachexia Definition a multifactorial syndrome characterized by severe body weight, fat and muscle loss and increased protein catabolism due to underlying disease(s) Increases patients morbidity and mortality Compared to other types of malnutrition, individuals with cachexia had the highest in hospital mortality 11.7% Reference: Statistical Brief #210. Healthcare Cost and Utilization Project (HCUP). September 2016. Agency for Healthcare Research and Quality, Rockville, MD. www.hcup-us.ahrq.gov/reports/statbriefs/sb210-malnutrition-hospital-stays-2013.jsp. 31 Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) cachexia-anorexia in chronic wasting diseases and nutrition in geriatrics. file:///users/nancymunoz/downloads/350_0_nl_8.pdf Cachexia Cannot be reversed with nutrition interventions Even if the patient ingests more calories than needed, lean body mass will be lost 32 Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) cachexia-anorexia in chronic wasting diseases and nutrition in geriatrics. file:///users/nancymunoz/downloads/350_0_nl_8.pdf 16

What is the nutrition status of our patients? Long Term Care Setting 20% nursing home residents presents with some form of malnutrition Prevalence ranged from 1.5-66.5% Due to variable malnutrition definitions Reference: Bell CL, Lee AS, Tamura BK. Malnutrition in the nursing home. Curr Opin Clin Nutr Metab Care. 2015 Jan;18(1):17-23. doi: 10.1097/MCO.0000000000000130. Review. PubMed PMID: 25394167. 33 Nutrition Risk for Developing Pressure Injuries Unintended weight loss Undernutrition Increased nutrient needs Malnutrition Dehydration Low BMI Inadequate food and fluid intake Inability to feed self 34 17

Nutrients and Wound Healing Malnutrition: insufficient calories, protein, or other nutrients needed for tissue maintenance and repair. Reference: References 1. White JV, Guenter P, Jensen G, et al. Consensus statement of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition: Characteristics recommended for the identification and documentation of adult malnutrition (undernutrition). J Acad Nutr Diet. 2012;112(5):730-738. 2017 National Pressure Ulcer Advisory Panel www.npuap.org Nutrients and Wound Healing 36 Nutrients: Essential to support health, skin integrity, and pressure injury healing Carbohydrates Provide glucose to support normal cellular activities Protein synthesis Secretion of hormones and growth factors Calories are needed to support the inflammatory process, angiogenesis, collagen deposition Prevent protein breakdown as an energy source 18

Nutrients and Wound Healing 37 Nutrients: Essential to support health, skin integrity, and pressure injury healing Protein Immune system: Initiate healthy inflammatory response process for wound healing Activate macrophages (clean the wound), release cytokines to trigger reactions essential for wound healing Protein Calorie Malnutrition can contribute to increased susceptibility to infection, decreased collagen and granulation tissue development during proliferative stage of wound healing Nutrients and Wound Healing Nutrients: Essential to support health, skin integrity, and pressure injury healing Fats Dense source of calories Essential component of cell membranes Essential fatty acid deficit interferes with the body's ability to have a normal immune response 38 19

Nutrients and Wound Healing Nutrients: Essential to support health, skin integrity, and pressure injury healing Vitamins and Minerals: Vitamin C Immune response Cell division (mitosis) Monocyte movement into wound tissue -- Macrophages during inflammatory phase Deficiency: Produces capillary fragility and decreased wound strength 39 Nutrients and Wound Healing Nutrients: Essential to support health, skin integrity, and pressure injury healing Vitamins and Minerals: Vitamin A Important for cell mediated immune function, collagen synthesis, and cross linking Counteracts delay in wound healing seen in presence of steroid use, diabetes, and radiation damage Deficiency: can contribute to increased susceptibility to infection, decreased collagen and granulation tissue development during proliferative stage of wound healing 40 20

Nutrients and Wound Healing Nutrients: Essential to support health, skin integrity, and pressure injury healing Vitamins and Minerals: Vitamin B Essential co-factors in enzyme activity Thiamine, riboflavin, vitamin B 12, and pyridoxine Important in collagen matrix synthesis Deficiency Have an indirect effect on wound healing by contributing to host resistance impaired antibody formation and white blood cell function increases susceptibility to infections 41 Nutrients and Wound Healing Nutrients: Essential to support health, skin integrity, and pressure injury healing Vitamins and Minerals: Vitamin E and K Vitamin E can interfere with the role of Vitamin A Vitamin K deficiency can contribute to decreased coagulation, thus impairing the inflammatory phase of healing 42 21

Nutrients and Wound Healing Nutrients: Essential to support health, skin integrity, and pressure injury healing Vitamins and Minerals: Iron Iron is essential for improving tissue perfusion Transporting oxygen to the tissues Necessary for collagen synthesis Iron deficiency can contribute to increased tissue ischemia impaired collagen cross-linking Decreased wound strength 43 Nutrients and Wound Healing Nutrients: Essential to support health, skin integrity, and pressure injury healing Vitamins and Minerals: Zinc Stimulates the activity of more than 100 enzymes Necessary for membrane stability Maturation of collagen in the proliferative and remodeling phases of wound healing Deficiency can decrease rates of fibroplasia and collagen synthesis wound strength impair immune response, increasing susceptibility to recurrent infections 44 22

Pressure Injury Prevention and Treatment Nutrition Guidelines 2014 2017 National Pressure Ulcer Advisory Panel www.npuap.org 2014 NPUAP-EPUAP & Pan Pacific Injury Alliance Clinical Practice Guidelines Nutrition Recommendations Nutrition screening Nutrition assessment Care planning Energy intake Protein intake Hydration Vitamins and minerals 46 23

NPUAP Pressure Injury Prevention Take Home Message 47 Clinical Characteristics of Malnutrition Academy of Nutrition and Dietetics ASPEN Malnutrition: Any type of nutrition imbalance Undernutrition» lack adequate calories, protein, or other nutrients needed for tissue maintenance and repair Over nutrition Reference: Hand RK, Murphy WJ, James A. Lee JA, Parrott JS, Ferguson M, Skipper A, Steiber A. Validation of the Academy/A.S.P.E.N. Malnutrition Clinical Characteristics. 2016. Journal of the Academy of Nutrition and Dietetics; 116 (5), Pages: 856-864 NPUAP Pressure Injury Prevention Take Home Message Hospitalized patients are at risk undernutrition NPO Disease process Unplanned weight change/ insidious weight loss Accurate height and weight Healthy Meal Pattern and adequate fluids Food first Oral nutrition supplements 48 24

Resources 2017 National Pressure Ulcer Advisory Panel www.npuap.org Offloading Preventing and Treating Arthur Stone, DPM Board Member NPUAP 2017 National Pressure Ulcer Advisory Panel www.npuap.org 25

62 Disclosures NPUAP Board Member Consultant Dabir Surfaces Consultant/Speaker Smith & Nephew 63 26

Objectives Discuss Why Off-loading is Important Discuss Risk Factors Discuss the NPUAP-EPUAP 2014 International Pressure Ulcer(Injury) Prevention & Treatment Guidelines Discuss evidence-based pressure injury prevention and treatment 64 Common Areas for Pressure Injuries 65 27

Risk factors 66 67 28

68 69 29

70 71 30

Repositioning and Early Mobilization Underlying cause of Pressure Injuries cannot form without loading, Frequency Repositioning Techniques Devices Mobilization International GuidelIne: Pgs. 91-101 72 General Off-Loading Techniques Reposition ALL individuals at risk or with existing pressure injuries, unless contra-indicated Consider support surface selection Repositioning Bed/Seated individuals International Guideline: Pgs. 91-101 73 31

74 Prevention Dressings 75 32

76 International NPUAP/EPUAP Prevention and Treatment of Pressure Ulcers(Injuries): Clinical Practice Guideline Repositioning and Mobilization Repositioning to Prevent and Treat Heel Pressure Ulcers(Injuries) Support Surfaces International Guideline: Sections, Repositioning and Early Mobilization/Prevent and Treat Pressure Ulcers/Support Surfaces 77 33