Presented by: Mariam Boulas Veronica Dascalu Pardis Payami

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Presented by: Mariam Boulas Veronica Dascalu Pardis Payami Introduction Carbohydrates are made up of carbon, oxygen, and hydrogen with this proportion: CH 2 O Major source of energy fuel in the body glucose RDA : 130 g/d for adults Three major types: Monosaccharides (simple sugars cane sugar) Disaccharides (simple sugars lactose) Polysaccharides (complex starches) 1

Introduction Metabolic pathways of carbohydrates : Glycolysis: glucose pyruvate Tricarboxylic acid cycle (TCA): pyruvate Acetyl- CoA TCA Glycogenesis: glucose glycogen Glycogenolysis: glycogen glucose Gluconeogenesis: non-carbohydrate sources glucose The Talk about Carbohydrates and Exercise Carbohydrates have been studied in the aerobic exercise realm for many years Carbohydrates are considered the main fuel for aerobic exercise capacity Carbohydrates are suggested to improve aerobic exercise by decreasing muscle glycogen use, therefore increasing performance Carbohydrates are suggested to replenish muscle glycogen after exercise causing a shorter recovery period 2

Jeukendrup, A. E., Hopkins, S., Arago n-vargas, L. F., & Hulston, C. (2008). No effect of carbohydrate feeding on 16 km cycling time trial performance. European Journal of Applied Physiology, 104, 831 837. Purpose To investigate the effect of carbohydrates ingestion during high intensity exercise performance lasting approximately 25 minutes 3

Methods Subjects: twelve endurance trained male cyclists aged 19 41 Inclusion criteria: Had experience in 16 km time trial (had at least done 5 times in the last 3 years) were training at least three times a week had been involved in competition for at least 2 years Methods Each subject completed 3 simulated 16 km trials. Subjects consumed one time carbohydrate drink and a water placebo drink twice. Time of consumption was 5 minutes before the start and at 25, 50, and 75% of completion of the time trial. Double blind crossover design 4

Results No significant differences were observed in: The time to complete the time trials with either treatment Power output during the time trials Heart rate average Discussion & Conclusion Different mechanisms: In prolonged exercise the role of carbohydrates is to maintain blood glucose level and high rates of carbohydrate oxidation During a short and high intensity exercise the blood glucose concentrations do not decrease, but it may increase because the hepatic glucose is increased 5

Discussion & Conclusion Ingestion of carbohydrate-electrolyte solution did not improve performance during a simulated 16 km cycling time trial compared with a placebo drink. Article s Short Message Carbohydrates do not improve performance in short duration and high intensity exercise. Implication It is important to know that CHO feeding during short duration and high intensity exercise become impractical for athletes. 6

Evaluation (+) Choosing subjects Healthy VO2max test Diet record Activity pattern Well trained Accurate time of trials (-) Cannot be generalized Male subjects Small sample size 23 references (1986-2004) Easy to follow Resistance Exercise & Carbohydrates Past &Recent Hype TRADITIONAL -PAST RT is primarily anaerobic using adenosine triphosphate (ATP), creatine phosphate ADP ATP Muscle glycogenolysis and glycolysis play a minor role is RT PRESENT Carbohydrate use may increase performance and exercise capacity during RT Carbohydrate use may maintain or save muscle glycogen stores during RT Carbohydrate use after exercise may help replenish muscle glycogen loss 7

Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise Brown, V.A., Dumke, C.L., Kang, J., McAnulty, L.S., Mcnulty, S.L., Nieman, D.C., Utter, A.C. (2005). Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise. Journal of Strength and Conditioning Research, 19(4), 939-943. Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise Purpose: The study looked at the relationship between carbohydrate consumption and perceived exertion during a RT workout. Question: Does carbohydrate supplementation increase performance and effort during RT? 8

Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise (cont.) Methods: - 30 male subjects (19-27 yrs.) - Double blind design ( CHO group/placebo group) - Pre-exercise assessment: 1RM and unweighted 10 exercises (4sets/10 reps) - Borg Scale: 6-20 Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise (cont.) Methods (cont.): - CHO (liquid) or placebo consumption 10am, 3pm, 15-30 mins before exercise, and during exercise - Recording of RPE of overall body exertion and muscle specific exertion after exercises in both groups Inclusion Criteria: - minimum of 6 months total body training experience - were able to back squat 1.25 their body mass 9

Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise (cont.) Results: - Carbohydrate supplementation did not effect the RPE between the two groups. Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise (cont.) Discussion & Conclusion: - Carbohydrate supplementation during RT did not effect RPE. - Carbohydrate supplementation during RT bout does not provide any psychological benefit on RPE results. - Other benefits of carbohydrate supplementation should be taken into account, such as an increase in work output and recovery time. 10

Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise (cont.) (-) Evaluation - small sample size - male only - carbohydrate quality and form - overall dietary intake not mentioned - psychological effect - timing of supplementation (+) - strong background information - opportunity for more in-depth research Effects of Supplement Timing and Resistance Exercise on Skeletal Muscle Hypertrophy Cribb, P.J., Hayes, A. (2006). Effects of Supplement Timing and Resistance Exercise on skeletal Muscle Hypertrophy. Medicine & Science in Sports & Exercise, 38(11), 1918-1925. 11

Effects of Supplement Timing and Resistance Exercise on Skeletal Muscle Hypertrophy Purpose: - Examine the effect of supplementation timing on RT muscle hypertrophy, strength, and body composition before and after a workout or at other hours not close to the workout during a 10 week RE program. Effects of Supplement Timing and Resistance Exercise on Skeletal Muscle Hypertrophy (cont.) Methods: - 17 males - single-blind, randomized protocol - Two groups: PRE/POST and MOR-EVE - Assessments completed 1st and 10th week of study: 1RM (3exercises), body composition, and vastus lateralis muscle biopsies for glycogen, creatine, and contractile protein. - Supplementation: protein/creatine/glucose 12

Effects of Supplement Timing and Resistance Exercise on Skeletal Muscle Hypertrophy (cont.) Inclusion Criteria: - no history of anabolic steroid use - 6 months on a training program - no use of ergogenic supplementation in the past 12wks. - agree not to take any supplementation or nonprescription drugs during the study Effects of Supplement Timing and Resistance Exercise on Skeletal Muscle Hypertrophy (cont.) Results: - PRE/POST group showed increased lean body mass and 1RM strength. The change in body composition was supported by an increase in the size of type II fibers and contractile protein. There was also an increase in glycogen after the training program. 13

Effects of Supplement Timing and Resistance Exercise on Skeletal Muscle Hypertrophy (cont.) Discussion & Conclusion: - Although the supplementation was a mixture of protein and CHO, the study suggests that CHO may have helped to spare muscle glycogen thus, enabling greater work capacity during RT or subsequent RT sessions. Effects of Supplement Timing and Resistance Exercise on Skeletal Muscle Hypertrophy (cont.) Evaluation (+) (-) - easy to understand - clear explanations and background information - males only - small sample size - no independent CHO supplementation 14

Take Home Message for Resistance Training Carbohydrates may be used to help spare muscle glycogen allowing increased work capacity/force during workouts and in subsequent workout sessions. Effect of CHO Loading Patterns on Running Performace Chen, Y., Wong, H. S., XU, X., Hao, X., Wong, C. K., & Lam, C. W. (2008). Effect of CHO Loading Patterns on Running Performance. International Journal Sport Nutrition, 29:598-606. 15

Some abbreviation and terminology Isoenergetic: showing equal force or activity Carbohydrates: CHO Glycemic Index: GI Definition: is a ranking of foods based on their actual postprandial blood glucose response as compared to a reference food Glycemic load: GL Definition: measures both quantity and quality of the dietary CHO consumed Purpose To examine the impact of 3-day CHO loading with different GI and GL meals on running performance and subsequent metabolic responses 16

Introduction Fatigue could be a result of prolonged exercise and the depletion of the body s stored muscle glycogen CHO loading: To increase the stored muscle glycogen Has a positive impact on performance during exercise event that lasts over 90 min Methods Subjects: 9 healthy male runners (they performed a 1 hr run at 70% VO2 max followed a 10 km performance run after 3-day diet adaptation) Medical history questionnaires and running ability were obtained No history of diabetes Experiential design: 3 different standardized pre-load treadmill performance runs were completed 3-day CHO loading with different GI and GL meals after a 1-h exhaustive run followed by a standardized preloaded exercise protocol 17

Methods Performed a glycogen-depletion exercise Randomly assigned to 3 trials HH LL HL High GI Low GI High GI High GL Low GL Low GL Methods Completed 3-d food diary record before the 3 d before introducing GI/GL different diets Avoid alcohol & caffeine; performing strenuous exercise a day before the main trial 1 st day 2nd day 3rd day 4th day 1-h exhaustive exercise 3o min run at 80% VO2 max Then, another 30 min at 70% VO2 max Why: to reduce the muscle glycogen Light exercise training: 20 min run at 70% VO2 max on the treadmill Light exercise training: 20 min run at 70% VO2 max on the treadmill Standardized exercise protocol 18

Methods Afterward, subjects were seated in a quiet area in the lab Blood concentration and perceived rating gut fullness were assessed 2-h postprandial Results The performance in the LL trial was improved comparing to HL trail High BS conc. were observed in high CHO trial (HH, LL) during exercise and the recovering period comparing the low CHO trial (HL) No difference in the plasma insulin values were observed in the 3 trails during exercise and recovering period 19

Discussion & Conclusion Improved endurance performance and improved recovery from prolonged exercise were observed when low GI meals were consumed comparing to high GI meal Studies showed that pre-exercise ingestion of HGI CHO produces immediate hyperglycemic responses causing rapid drop in the plasma glucose conc. Discussion & Conclusion Low GI and low GL is more effective in improving endurance performance compared to low CHO diet with High GI and low GL In conclusion, the main factor that has an impact on metabolism and endurance run performance appears to related to the amount rather than the nature of CHO consumed. 20

Implication It is important for endurance runner athletes to consume adequate CHO intake to be able to perform better Evaluation (+) 3 day dietary record was obtained and Registered Dietitian was involved in the process (-) Small no. of subjects. Conclusions are limited to male, could not be generalized to other population 32 references 21

Effects of Carbohydrate Ingestion 15 min before Exercise on Endurance Running Capacity Tokmakidis, S. P., & Karamanolis, I. (2008). Effects of Carbohydrate Ingestion 15 min Before Exercise on Endurance running capacity. Apply Physiology Nutrition Metabolism, 33: 441-449. Purpose To test the effect of pre-exercise glucose ingestion on exercise metabolism and endurance running capacity during prolonged treadmill exercise 22

Introduction Many research studies showed that CHO ingestion before exercise has been shown to affect metabolic response, substrate utilization during performance, and exercise time to exhaustion There is a relationship between the Consumption of glucose and hyperinsulinaemia 30-60 min before strenuous exercise Methods Subjects: 11 recreational runners 10 males and 1 female Insulin sensitivity and insulin secretion were assessed using the oral glucose tolerance test. All subjects had normal response Maximal oxygen consumption (VO2 max) was measured Experiential design: Each subject was involved in 2 running trials on treadmill to exhaustion Glucose (G) and Placebo (CON) solutions were ingest 15 min before the onset of exercise 23

Results Endurance time, oxygen consumption: Subjects who were in the G group ran longer than the CON group Date showed oxygen consumption during exercise was not different between the two trials Results Serum glucose and plasma insulin: After 15 min ingestion, serum glucose levels were significantly higher in the G group vs the CON Serum glycerol and serum FFAs: Serum FFAs was lowered in the G group vs the CON CHO and fat oxidation: Throughout the exercise, there was no difference in CHO oxidation in both trials, but fat oxidation was lowered in the G trial compared to the CON trial 24

Discussion & Conclusion This study agreed with other research that there is a positive relation between CHO ingestion and exercise performance Other studies showed that glucose ingestion before exercise caused hypoglycaemia during the first min of exercise Causes could be possibly due to: The time of glucose supplementation The amount of glucose ingested before the exercise Discussion & Conclusion During this study, none of the subjects were hypoglycemic Researcher suggesting that fatigue was delayed and performance time improved because: Availability of circulating serum glucose which provided extra source of energy Reserved muscle glycogen stores 25

Implication CHO ingestion before exercise is essential To maintain good glycemic control To provide extra energy To help runners to perform better Evaluation (+) (-) Easier to read, follow and understand Included male and female subjects Not enough subjects to relate to other populations 15 references only 26

Conclusion Benefits of carbohydrates in exercise depend on : Amount and time of consumption Type of carbohydrates Duration and intensity of exercise As RDs educating athletes on the essential of carbohydrate intake Higher needs of CHO which help athletes with their physical endurance and metabolism References Brown, V.A., Dumke, C.L., Kang, J., McAnulty, L.S., Mcnulty, S.L., Nieman, D.C., Utter, A.C. (2005). Carbohydrate Supplementation and Perceived Exertion During Resistance Exercise. Journal of Strength and Conditioning Research, 19(4), 939-943. Chen, Y., Wong, H. S., XU, X., Hao, X., Wong, C. K., & Lam, C. W. (2008). Effect of CHO Loading Patterns on Running Performance. International Journal Sport Nutrition, 29:598-606. Cribb, P.J., Hayes, A. (2006). Effects of Supplement Timing and Resistance Exercise on skeletal Muscle Hypertrophy. Medicine & Science in Sports & Exercise, 38(11), 1918-1925. Gropper, S. S., Smith, J. L., & Groff, J. L. (2004). Advanced Nutrition & Human Metabolism 4th edition. United States: Thomson/ Wadsworth. Jeukendrup, A. E., Hopkins, S., Arago n-vargas, L. F., & Hulston, C. (2008). No effect of carbohydrate feeding on 16 km cycling time trial performance. European Journal of Applied Physiology, 104, 831 837. Tokmakidis, S. P., & Karamanolis, I. (2008). Effects of Carbohydrate Ingestion 15 min Before Exercise on Endurance running capacity. Apply Physiology Nutrition Metabolism, 33: 441-449. Volek, J.S. (2004) Influence of Nutrition on Responses to Resistance Training. Medicine and Science in Sports and Exercise, 36(4), 689-696. 27

Any Questions??? 28