Surgical Off-loading. Reiber et al Goals of Diabetic Foot Surgery 4/28/2012. The most common causal pathway to a diabetic foot ulceration

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Reiber et al. 1999 Surgical Off-loading The most common causal pathway to a diabetic foot ulceration Alex Reyzelman DPM Associate Professor California School of Podiatric Medicine at Samuel Merritt University Co-Director, UCSF Center for Limb Preservation NEUROPATHY + DEFORMITY + MINOR TRAUMA = ULCERATION Reiber et al. Diabetes Care 1999 Goals of Diabetic Foot Surgery Reduction of pressure Prevention of ulceration / amputation Increased function Relief of pain Allow for proper accommodation in shoes 1

Rigid Foot Deformities Any deformity that could not be reduced manually Rigid deformities CANNOT be offloaded Metatarsal Head Resection for Diabetic Foot Ulcers Griffiths et al, Arch Surg 1990; 125; 832-835 Retrospective review of diabetic patients who underwent metatarsal head resections for recalcitrant diabetic foot ulcerations 34 met head resections on 25 patients in 32 operations Mean age 58 19 males / 6 female Indications Non healing ulcers (22) Infected ulcers (5) Transfer lesions (3) Ulcerations after amputations (2) Painful callus (2) 2

Metatarsal Head Resection for Diabetic Foot Ulcers Griffiths et al, Arch Surg 1990; 125; 832-835 Mean time of ulceration pre-op = 9.0 months Mean f/u 13.8 months Mean time for ulcer healing post-op = 2.4 months No recurrence in same area 3 transfer lesions were re-operated Retrospective study of single digital arthroplasties in 31 DM and 33 non- DM patients Purpose was to compare morbidity and outcomes of prophylactic surgery among diabetics and non-diabetics Avg. f/u of 3 yr with no significant difference 96.3 remain ulcer free Retrospective review of outpatient percutaneous flexor tenotomies in diabetic patients with claw toes and ulceration Inclusion Criteria Mild to moderate rigidity Distal ulceration Exclusion Criteria Absence of pulses Cellulitis Results 34 toes in 14 patients 8 male / 6 female 24 ulcers / 10 at risk 3 Osteomyelitis Average duration of ulceration 11 months Mean f/u 13 months Ulcers healed within 3 weeks No complications No recurrence No hyperextension deformities seen 3

Case control study to evaluate the complications and outcomes of 1 st MPJ arthroplasty compared to standard, nonsurgical management of hallux IPJ wounds 21 Surgical patients underwent Keller type arthroplasty 20 age, sexmatched patients receiving standard non-surgical care 6 month f/u Results Ulcer healing 24 days vs. 67 days Ulcer recurrence 5% vs. 35% Infection 40% vs. 38% Retrospective cohort study to evaluate outcomes of operative versus non-operative treatment of ulcerations sub 5 th metatarsal head in people with diabetes 22 patients underwent 5 th met head excision 18 patients received standard non-operative care 6 month f/u Re-ulceration rates 4.5% vs. 28% Prospective, randomized trial addresses: Healing rate in 6 months Duration of healing time Prevalence of recurrence Prevalence of infection Group A (n=20) Non-operative therapy Dressing changes Offloading Group B(n=21) Operative therapy removal of ulcer, removal of bone, closure with sutures 5 days IV abx 4

Conservative Surgical Approach Versus Nonsurgical Management for Diabetic Neuropathic Foot Ulcers: a Randomized Trial Piaggesi et al, Diab Med, 15: 412-17, 1998 Pan Metatarsal Head Resection Giurini et al JAPMA 83(2), 1993 Healing Rate Duration of Healing Recurrence Rate Infection Rate Group A (Non-operative) Group B (Operative) 19/24 (79%) 21/22 (95%) 129 days 47 days 8/19 (41%) 3/21 (14%) **transfer lesions** 3/24 (12.5%) 1/22 (4.5%) 34 panmetatarsal head resection Average follow-up of 20.9 months Overall success rate of 97% Most common complication was regrowth of bone resulting in development of new ulceration Partial Calcanectomy in the Treatment of Recalcitrant Heel Ulcerations Randall et al, JAPMA 95(4); 335-341, 2005 Literature Review 148 cases since 1931 89% healing rates DM and PVD Incisional approaches Retrospective review 8 patients underwent partial calcanectomy for chronic non-healing ulcerations 8 patients / 9 feet 7/9 (78%) healed without recurrence 2 failures: PVD / Improper post-op offloading Ambulatory status unchanged post-op Indications for Surgery Unstable deformity not amenable to bracing Deformity with current non healing ulceration Deformity with potential for recurrent ulceration Surgical Procedures Exostectomy Arthrodesis 5

Charcot Deformity Brodsky and Rouse Clin Ortho 296 Nov, 1993 Achilles Tendon Lengthening Armstrong et al JBJS 81A(4) April 1999 12 patients who underwent exostectomy Average follow-up was 25 months 11 of 12 patients had Type I midfoot involvement 11 of 12 patients remained healed 10 Subjects with DM All UT DM Foot Risk Category 3 All with pre-operative AJ DF <10 degrees TAL Performed Peak plantar forefoot pressure assessments pre and 8-weeks postoperatively Achilles Tendon Lengthening Conclusions Operative Management of Diabetic Foot Ulcers Peak Plantar Forefoot Pressure (N/cm2) 100 90 80 70 60 50 40 30 20 Preoperative Postoperative Reduction in postoperative peak plantar pressure (86.1 ± 9.4 vs. 63.3 ± 13.2 N/cm 2, p < 0.001). Increase in ankle joint range of motion eight weeks, postoperatively (0.4 ± 3.1 vs. 8.7 ± 2.3, p < 0.001). In order to treat wounds, we must understand the factors associated with the etiology of those wounds Healing success is related to the tenants of good wound care EBM exists to support surgical management of appropriately selected patients 6

Thank You 7