MATRIX-INDUCED AUTOLOGOUS CHONDROCYTE IMPLANTATION PHYSICAL THERAPY PRESCRIPTION

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UCLA OUTPATIENT REHABILITATION SERVICES! SANTA MONICA! WESTWOOD 1000 Veteran Ave., A level Phone: (310) 794-1323 Fax: (310) 794-1457 1260 15 th St, Ste. 900 Phone: (310) 319-4646 Fax: (310) 319-2269 FOR APPTS, CALL: (310) 794-1323 FAX: (310) 794-1457 MATRIX-INDUCED AUTOLOGOUS CHONDROCYTE IMPLANTATION PHYSICAL THERAPY PRESCRIPTION Diagnosis: s/p ( LEFT / RIGHT ) Matrix-Induced Autologous Chondrocyte Implantation (Femoral Condyle) Location: Additional Procedures: Date of Surgery: Pre-opeartive Rehabilitation -Patient education on the surgical procedure, tissue maturation, and relevance to post-operative activity progression -Physical preparation of the patient and knee N/A Promote full active ROM to reduce preoperative contractures N/A FORMCHECKBOX Lower-limb resistance and joint ROM exercises to improve bilateral strength, mobility, balance, and general function of muscles and connective tissue FORMCHECKBOX Upper-limb and trunk resistance exercises to assist early post-operative weight-transfer activities and crutch ambulation FORMCHECKBOX Cardiovascular exercise to improve general health, promoting weight reduction and a faster recovery from surgery Phase 1 (0-7 days post-surgery) -Avoid excessive WB (>20% BW) -Avoid shear forces generated across the articular surface -Maintain lower-limb mobility, muscle tone, and circulation -Reduce post-operative pain and edema Patient is NWB, 0% of BW through the operated limb Passive and active assisted knee ROM from 0 to 30

Protective brace set at 0 to 30, worn 24 hours per day FORMCHECKBOX Passive and active assisted knee flexion and extension ROM exercises (0 to 30 ) FORMCHECKBOX CPM (0 to 30 ) 12 to 24 hours post-surgery for a minimum of 1 hour daily FORMCHECKBOX Active ankle dorsilflexion and plantar flexion FORMCHECKBOX Isometric contraction of the quadriceps, hamstrings, adductors, and gluteal musculature FORMCHECKBOX Instruction and practice in proficient non WB ambulation (0% BW) using 2 crutches Phase 2 (2-3 weeks post-surgery) -Pain-free knee flexion to 90 -Pain-free and full passive knee extension -Proficient heel-toe gait at 20% BW with 2 crutches -Regain active quadriceps control -Reduce post-operative pain and edema -Proficiency in undertaking home exercise program Progress from 0% of BW (weeks 1 and 2) to 20% BW (week 3) Passive active knee ROM from 30 (week 2) to 90 (week 3) Knee brace 0 to 30 (week 1) to 0 to 45 (week 3) FORMCHECKBOX Continue phase 1 exercises FORMCHECKBOX Patellar mobilization in all directions FORMCHECKBOX CPM employed if possible FORMCHECKBOX Isometric quadriceps and quadriceps-hamstring cocontraction activities with and without the use of NMES FORMCHECKBOX Introduce SLR activities (hip, flexion, abduction, adduction, extension) FORMCHECKBOX Introduce hydrotherapy, deep-water walking (forward, backward, sideways), heel raises, squats, straight-leg hip flexion, extension, abduction, and circumduction (to begin at week 3) Phase 3 (4-6 weeks post-surgery) -Pain-free knee flexion to 125 -Proficiency in performing all home-based exercises, including an SLR -Pain-free gait using 1 crutch and 50% BW through operated limb Progress from 20% of BW (week 4) to 50% BW (week 6) Progress active knee ROM from 110 (week 4) to 125 (week 6) Knee brace 0 to 60 (week 4) to full flexion permitted (week 6)

FORMCHECKBOX Continue phase 1 and 2 exercises FORMCHECKBOX Increase demand of plinth-based exercises, including SLR with external hip rotation, sidelying gluteal exercises in knee flexion FORMCHECKBOX Introduce hamstring and calf stretches FORMCHECKBOX Introduce seated or standing machine-based exercises, including standing calf raises (dependent on WB status), weighted hip abduction and adduction, trunk strengthening (supine sit-ups, weight-supported trunk flexion) FORMCHECKBOX Introduce recumbent cycling (week 5) FORMCHECKBOX Hydrotherapy: continue phase 2 exercises, plus active knee flexion (with resistive devices), shallow-water walking (waist-depth), heel raises, step-ups/step-downs, lunges, cycling, scissor kicks, lower-limb flexibility and proprioception exercises Phase 4 (7-12 weeks post-surgery) -Pain-free and full active knee ROM with anatomical limits -Pain-free 6-minute walk test without the use of walking aids -Pain-free upright cycling without a protective knee brace -Proficiency in performing home and clinic-based exercise for the independent continuation of post-discharge rehabilitation Progress from 50% of BW (week 7) to full WB (week 8), pending clearance from orthopaedic specialist Progress to full active knee ROM (weeks 7-8) Full flexion permitted FORMCHECKBOX Continue phase 2 and 3 exercises FORMCHECKBOX Further knee flexion through intensive quadriceps stretching and passive rowing ergometry FORMCHECKBOX Introduce bridging exercises and weighted knee flexion (week 8) FORMCHECKBOX Introduce proprioceptive WB exercises FORMCHECKBOX Introduce upright stationary cycling (weeks 9-12) FORMCHECKBOX Continue phase 2 and 3 hydrotherapy exercises, plus pattern kicking (weeks 11-12) Phase 5 (3-6 months post-surgery) -Normal gait pattern without pain, walking aids, or a knee brace -Ability to negotiate stairs and mild gradients without pain -Return to work (dependent on occupational demands) -Proficiency in performing all full WB strengthening and proprioception activities Full WB, no crutches Full and pain-free active knee ROM No brace

FORMCHECKBOX Continue phase 3 and 4 exercises FORMCHECKBOX Introduce modified non-wb exercises (eg. terminal leg extension), dictated by graft location and size FORMCHECKBOX Introduce modified WB exercises (eg. single-leg heel raises, leg press, squats, lunges, steps) FORMCHECKBOX Increase duration and intensity of stationary and outdoor road cycling FORMCHECKBOX Introduce rowing ergometry and elliptical trainers FORMCHECKBOX Hydrotherapy generally not required, pool may be used for ongoing cardiovascular exercise Phase 6 (6-9 months post-surgery) -Hamstring and calf strength within 90% of the contralateral limb -Ability to tolerate pain-free walking distances of more than 5 to 10 km -Ability to effectively negotiate uneven terrain and soft sand -Return to preoperative low-impact recreational activities Full WB, no crutches Full and pain-free active knee ROM No brace FORMCHECKBOX Continue phase 3 to 5 exercises FORMCHECKBOX Ongoing progression of WB and non-wb activities with respect to duration, intensity, proprioceptive component, and overall complexity FORMCHECKBOX Exercises employed should begin to replicate what is required for the patient s individual activity goals Phase 7 (9-18 months post-surgery) -Quadriceps strength within 90% of the contralateral limb -Ability to perform all activities of daily living pain free -Ability to commence a progressive running program at 9 to 12 months -Resumption of dynamic recreational and sporting activities; however, sports that generate high compression, shear, and torsional loads should be avoided until 12 to 18 months postsurgery Full WB, no crutches Full and pain-free active knee ROM No brace FORMCHECKBOX Continue phase 3 to 6 exercises pertinent to the patient s individual activity goals FORMCHECKBOX Ongoing progression of WB activities with respect to duration, intensity,

proprioceptive component, and overall complexity FORMCHECKBOX Introduction of agility and plyometric drills relevant to the patient s individual activity goals Treatment: times per week Duration: weeks Home Program **Please send progress notes. Physician s Signature: Date: Kristofer J. Jones, M.D., Attending Orthopaedic Surgeon MACI PAGE \* MERGEFORMAT 4 MACI PAGE \* MERGEFORMAT 1 Place label here NAME OF PATIENT: MRN: Kristofer J. Jones, M.D. Sports Medicine, Shoulder Surgery and Cartilage Restoration UCLA Department of Orthopaedic Surgery David Geffen School of Medicine at UCLA 10833 Le Conte Avenue, 76-143 CHS Los Angeles, CA 90095-6902 Phone: (310) 825-6095 Fax: (310) 825-1311 CA License: A126262

Kristofer J. Jones, M.D. UCLA Department of Orthopaedic Surgery