Downloaded from irje.tums.ac.ir at 9:18 IRDT on Saturday September 15th 2018

Similar documents
. Neuropsychiatric Inventory (NPI) :

Development of a Caregiver Burden Questionnaire for the Patients with Dementia in Iran

Behavioral and psychological symptoms of dementia characteristic of mild Alzheimer patients

Gerardo Machnicki 1, Ricardo F. Allegri 1,2 *, Carol Dillon 1, Cecilia M. Serrano 1,2 and Fernando E Taragano 2 SUMMARY INTRODUCTION

Screening and Management of Behavioral and Psychiatric Symptoms Associated with Dementia

Factors related to Caregiver Burden in Caregivers of Patients with Parkinson s disease in Mumbai, India.

Caregiver Burden In Dementia: A Study In The Turkish Population

A wide range of neuropsychiatric disturbances commonly

Reliability of the Brazilian Portuguese version of the Neuropsychiatric Inventory (NPI) for patients with Alzheimer s disease and their caregivers

Clinical Trial Designs for RCTs focussing on the Treatment of Agitation in people with Alzheimer s disease

Neuropsychiatric symptoms and associated caregiver stress in geriatric patients with Parkinson s disease

The Neuropsychiatric Inventory Questionnaire: Background and Administration

Range of neuropsychiatric disturbances in patients with Parkinson s disease

Anosognosia, or loss of insight into one s cognitive

Coordinating Care Between Neurology and Psychiatry to Improve the Diagnosis and Treatment of Parkinson s Disease Psychosis

Neuropsychiatric Syndromes

Supplementary Online Content

Neuropsychiatric Inventory Nursing Home Version (NPI-NH)

Ian McKeith MD, F Med Sci, Professor of Old Age Psychiatry, Newcastle University

City, University of London Institutional Repository

Responsiveness of the QUALID to Improved Neuropsychiatric Symptoms in Patients with Alzheimer s Disease

World Journal of Pharmaceutical and Life Sciences WJPLS

CSF Aβ1-42 predicts cognitive impairment in de novo PD patients

Parkinsonian Disorders with Dementia

Behavioral and Psychological Symptoms of Dementia

Estimating the Validity of the Korean Version of Expanded Clinical Dementia Rating (CDR) Scale

Practice Concepts. Copyright 2006 by The Gerontological Society of America

DEMENTIA WITH LEWY bodies (DLB) is the

NEUROPSYCHOMETRIC TESTS

Psychiatric Morbidity in Dementia Patients in a Neurology-Based Memory Clinic

School of Health Science & Nursing, Wuhan Polytechnic University, Wuhan , China 2. Corresponding author

NeuroPharmac Journal ISSN: Alzheimer s Disease: Pharmacotherapy of noncognitive symptoms Aslam Pathan; Abdulrahman M.

Factors Contributing to Institutionalization in Patients with Huntington s Disease

Dementia is a common neuropsychiatric disorder characterized by progressive impairment of

The course of neuropsychiatric symptoms in dementia. Part II: relationships among behavioural sub-syndromes and the influence of clinical variables

DEPRESSIVE SYMPTOMS IN ADULT CHILD CAREGIVERS OF VERY OLD MEXICAN AMERICANS: A STUDY OF THE HEPESE

COPING STRATEGIES OF THE RELATIVES OF SCHIZOPHRENIC PATIENTS

Carers for older people with co-morbid cognitive impairment in general hospital: characteristics and psychological well-being

Across the Cognitive Impairment Continuum Increasing Patient Dependence is Associated with an Increase in Caregiver Burden

Acute Care Utilization by Dementia Caregivers Within Urban Primary Care Practices

Prevention, health promotion & early intervention in dementia

Discussion paper Convergence and Divergence of Apathy and Depression

Livia Pfeifer, 1 Reinhard Drobetz, 1 Sonja Fankhauser, 1 Moyra E. Mortby, 2 Andreas Maercker 1 and Simon Forstmeier 1.

ORIGINAL CONTRIBUTION. Response of Patients With Alzheimer Disease to Rivastigmine Treatment Is Predicted by the Rate of Disease Progression

The place for treatments of associated neuropsychiatric and other symptoms

Validation of apathy evaluation scale and assessment of severity of apathy in Alzheimer s diseasepcn_

N europsychiatric symptoms can induce marked disability

Quality of life of patients with Alzheimer s disease: Differential perceptions. between spouse and adult-child caregivers

The Reliability and Validity of the Korean Instrumental Activities of Daily Living (K-IADL)

Factors Influencing Satisfaction with Life in Female Nursing College Students with Irritable Bowel Syndrome

Behavioural Problems and Patterns of Psychopharmacological Treatment given in Elderly Patients with Dementia

PDF hosted at the Radboud Repository of the Radboud University Nijmegen

Samantha K. Holden, MD East 17th Avenue Campus Box B185 Aurora, CO Phone:

White matter hyperintensities correlate with neuropsychiatric manifestations of Alzheimer s disease and frontotemporal lobar degeneration

Number of Items. Response Categories. Part V: Specific Behavior Scales-Sleep Scales. Based on past month

Cognitive Reserve and the Relationship Between Depressive Symptoms and Awareness of Deficits in Dementia

The world is graying: Dementia is an alarming issue

Downloaded from umj.umsu.ac.ir at 20: on Friday March 22nd

C holinomimetic drugs constitute the first line of treatment

RESEARCH SNAPSHOT. Disability Care-giving dynamics and futures planning among ageing parents of adult offspring with intellectual disability

Behavioral and Psychologic Symptoms in Different Types of Dementia

Comment on administration and scoring of the Neuropsychiatric Inventory in clinical trials

Outcome measures in dementia care research

NEXT-Link DEMENTIA. A network of Danish memory clinics YOUR CLINICAL RESEARCH PARTNER WITHIN ALZHEIMER S DISEASE AND OTHER DEMENTIA DISEASES.

Dysphoric symptoms in relation to other behavioral and psychological symptoms of dementia, among elderly in nursing homes

Kinship and cohabitation in relation to caregiver burden in the context of Alzheimer's disease: a 24-month longitudinal study

The neuropsychiatry of dementia : psychometrics, clinical implications and outcome Kat, M.G.

Neuropsychiatric Symptoms of Patients With Progressive Supranuclear Palsy and Parkinson s Disease

Quality of Life in Patients with Parkinson s Disease

Application of World Health Organization Quality of Life Instrument, Short Form (WHOQOL-BREF) in measuring quality of life in patients with cataract

Cognitive impairment in Parkinson s disease: impact on quality of life of carers

Effect of neuropsychiatric symptoms of Alzheimer's disease on Chinese and American caregivers

Caregiver burden is increased in Parkinson s disease with mild cognitive impairment (PD-MCI)

PRESCRIBING FOR PEOPLE WITH DEMENTIA; SELECTED FINDINGS FROM POMH-UK QUALITY IMPROVEMENT PROGRAMMES (QIPS)

IT IS WELL known that individuals with dementia. Classifying eating-related problems among institutionalized people with dementia.

The effect of rehabilitation education program on family caregivers of stroke patients

CIC Edizioni Internazionali

Research Article The Natural History of Depression in Parkinson s Disease within 30-Month Follow-Up

Defense Mechanisms in Psychological Health and Sport Success of Athletes

Effects of two-year treatment with the cholinesterase inhibitor rivastigmine on behavioural symptoms in Alzheimer s disease

Effect of Dependency on Self-esteem among People with Dementia at the Dementia Day Care Centre.

T he prevalence of Parkinson s disease (PD) is nearly 1% in

Behavioural disturbances in dementia patients and quality of the marital relationship

Burden of behavioral and psychiatric symptoms in people screened positive for dementia in primary care results of the DelpHi-study René Thyrian

Songklanagarind Journal of Nursing Vol. 34, Supplement, January - April Sadee Hamilton* Abstract

Neuropsychiatric Manifestations in Vascular Cognitive Impairment Patients with and without Dementia

Disclosure statement

Neuropsychiatric disturbances such as delusions,

A pan-european study on outcome measures for psychosocial intervention research in dementia

Introduction ABSTRACT. Key words: dementia, Alzheimer s disease, neuropsychiatric symptoms, depression, apathy, agitation, neuropsychiatric inventory

Predicting Lewy Body Pathology in a Community-Based Sample With Clinical Diagnosis of Alzheimer s Disease

Research Article Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment

Cognitive Function in Early and Advanced Parkinson s disease

RESEARCH AND PRACTICE IN ALZHEIMER S DISEASE VOL 10 EADC OVERVIEW B. VELLAS & E. REYNISH

Investigating the correlation between personal characteristics and health status of Community- Living Elders and Intensity of Fear of Falling

Nature, prevalence and clinical significance. Barcelona, Spain

Joel Sadavoy MD, FRCP, Founder Geriatric Psychiatry Professor of Psychiatry and Pencer Chair in Applied General Psychiatry, Director Reitman Centre

Guidelines for the Management of Behavioural and Psychological Symptoms of Dementia (BPSD) Summary document for Primary Care

Known as both a thief and murderer,

MODERATORS OF THE RELATIONSHIP BETWEEN FAMILY CAREGIVER PROXY RATINGS AND PERSON WITH DEMENTIA SELF-RATINGS OF QUALITY OF LIFE

Transcription:

.5159 :2 7 1390 : 88989123 4 3 2 1 1 : 2 3 4. :. :. 84 : Burden Iranian Version of Caregiver.. Neuropsychiatric Inventory ().. 85. 2/4 39/3 : ebrahemen@gmail.com : 89/10/4 : 89/8/26: :. : 40 (116 58). : (1) ( ) (35) ). () ( (36).(1) ( ) (23) ().(4)

.(5) 95.(61012) ()..(7) (891011).(12) ) ( ) (......(11131415).. (Delusion)..(10) ().(10).(16). ) (. 84 ) (() 1388. Iranian Version of Caregiver Burden Neuropsychiatric Inventory.(1718) (Demographic).. (content) (construct) ) (Inter Rater (Frequency) %79 (Severity) %86.(61015) 3. )

: 3/ (. 12.(15) 1) (4 1) (3..(101518) Iranian Version of Caregiver Burden. 29 ) (. ) ( 98/6 99/3 100. ICC 97 94. 29) ( 4) (0 116 ) 0 (116.(17). Caregiver Burden 2. T test (ANOVA) (Correlation) ) (.. Dummy» «.» «. 84 ) (. 48 36) (. ) ( (6/7) 76/5 (4/9) 4/8. ) ( ) ( 10/7 45/1. 2/76 4/6. 85/7) (. 1. 58/85 96 102) (6 40 116) (58. 39/3 34/5 2/4 8/3 85. 1. Bi variate

/54 ( ) 1 12 (%14/3) 43 (%51/2) 30 (%23/8) 9 (%10/7) 53/54(8/11) 7212 10/24(5/2) 45/1 (32) 66 (%78/6) 12 (%14/3) 3 (%3/5) 3 (%3/5) 27 (%32/1) 39 (%46/4) 8 (%9/5) 10 (%12) 23 61 (777482) 926282 ( n =84) 1388 76/5(6/7) 48(57/1%) 36(42/9%) 4/8(4/9) 6 (%7/2) 12 (%14/3) 66 (%78/5) 10/7 (1/75) 2/76 4/6 (1/9) 50 (%59/6) 1 (%1/2) 30 (%35/7) 3 (%3/5) 62 (73/8) 16 (%19) 6 (%7/2) 16 68 14/83 (13/5) () ( /) () () ( /) ( ) () * 58/85 (25). *

: 5/ 1 84 ) (. (Pvalue <0/006) 0/302).(r= 2 Bivariate. 2 84 1388 (S.D) Pvalue r 14 (1/3) 0/55 (3/7) 1/47 0/040 0/229 25 (1/4) 0/85 (2/7) 1/5 0/604 0/058 24 (1/5) 0/76 (2/7) 1/27 0/185 0/149 33 (1/7) 1/25 (4/2) 2/7 0/293 0/118 18 (1/3) 0/64 (2/6) 1/13 0/943 0/008 28 (1/8) 1/2 (3/7) 2/21 0/032 0/239 19 (1/5) 0/77 (2/7) 1/24 0/034 0/237 17 (1/5) 0/75 (2/9) 1/42 0/046 0/222 2 (0/3) 0/05 (1/7) 0/2 0/843 0/024 21 (1/6) 0/85 (3/4) 1/66 0/032 0/238 29 (1/8) 1/25 (3/5) 2/26 0/521 0/072 7 (0/9) 0/3 (1/4) 0/38 0/306 0/115 * (13/5) 14/83 0/006 0/302 *

/6 (Pvalue <0/006). 21/7 (Pvalue <0/005) 27/8 25/6.(Pvalue<0/008). ( ) P Bivariate. 1/5 (P value<0/025).(pvalue<0/022) 1/7 3 (β) β 95 β t < 0/001 90/ 180 139/ 214 114/ 698 9 / 346 (Constant) 0/228 0/ 137 4/ 430 18/ 275 6/ 922 1/ 218 ( ) 0/232 0/ 114 21/ 547 8/ 182 12/ 929 1/ 206 0/372 0/ 089 21/ 547 8/ 182 6/ 683 0/ 898 0/710 0/ 050 15/ 953 10/ 924 2/ 515 0/ 374 0/008 0/ 439 44/ 166 7/ 001 25/ 584 2/ 750 0/593 0/ 077 30/ 027 17/ 314 6/ 357 0/ 536 0/168 0/ 150 31/ 891 5/ 681 13/ 105 1/ 394 0/006 0/ 433 36/ 999 6/ 355 21/ 677 2/ 826 0/005 0/ 337 46/ 877 8/ 753 27/ 815 2/ 915 0/056 0/ 199 5/ 812 0/ 077 2/ 867 1/ 945 0/025 0/ 233 0/ 191 2/ 765 1/ 478 2/ 295 0/022 0/ 213 0/ 243 3/ 076 1/ 659 2/ 340 < 0/001 0/ 366 16/ 141 4/ 835 10/ 488 3/ 706

: 57/ Backward ) (. Variance Inflation Factor(VIF) ) VIF 3 3/6 1/7 (. (co linearity). 3. 0/542 ) (.(R 2 =0/542).(5). ) (....(21).(10).(16) 14/8 (411).(615) 85...(6710) Bivariate....» «.» «21/7 27/8. 13/1. ).(Pvalue=0/168).(19)

... ) (.. 25/5.(Pvalue =0/008). (5620) ) (...(56192122) ) (..... Bivariate ) (2. ) (. ).(3. ) (.. ) (..» «. 116) (58 40

59/ :.. 8803279165 1. Bruns A and Iliffe S. Alzheimer s disease BMJ, 2009; 338: 46471. 2. Garre Olmo J, Herna ndez Ferra ndiz M and Lozano Gallego M. Burden and quality of life in carers of patients with Alzheimer type dementia. Rev Neurol. 2000; 31: 522 7. 3. Alzheimer s Association Report 2010, Alzheimer s disease facts and gures Alzheimer s Association, Alzheimer s & Dementia. 2010; 6:158 94. 4. CondeSala JL, GarreOlmo J, Turro Garriga O, Lo pez Pousa S and VilaltaFranch J. Factors related to perceived quality of life in patients with Alzheimer s disease: the patient s perception compared with that of caregivers, Int J Geriatr Psychiatry 2009; 24: 585 94. 5. SerranoAguilar PG, Lopez BJ and YanesLopez V. Impact on HealthRelated Quality of Life and Perceived Burden of Informal Caregivers of Individuals with Alzheimer s Disease. Neuro epidemiology 2006; 27 :136 42. 6. Allegri RF, Sarasola D, Serrano CM, Taragano FE, Arizaga RL, Butman J, et al. Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer s disease, Neuropsychiatric Disease and Treatment 2006; 2: 105 10. 7. Daniel I, Kaufer MD, et al. Assessing the Impact of Neuropsychiatric Symptoms in Alzheimer's Disease: The Neuropsychiatric Inventory Caregiver Distress Scale, Journal of the American Geriatrics Society. 1998; 46: 21015. 8. Cummings JL, Victoroff JI. Noncognitive neuropsychiatric syndromes in Alzheimer's disease. Neuropsychiatry Neuropsychol Behav Neurol 1990; 3: 14058. 9. Mendez MF, Martin RJ, Smyth KA, et al. Psychiatric symptoms associated with Alzheimer's disease. J Neuropsychiatry Clin Neurosci, 1993; 2: 2833. 10. Jeffrey L and Cummings MD. The Neuropsychiatric Inventory: Assessing psychopathology in dementia patients, Neurology,1997; 48. 11. Aarsland D, Jeffrey L. Cummings and Jan PL. Neuropsychiatricdiferencesbetweenparkinson sdisease withdementiaandalzheimer's Disease, Int. J. Geriatr. Psychiatry,2001; 16 :184 91. 12. Aarsland D, Brønnick K, Ehrt U, De Deyn PP, Tekin S, Emre M. et al. Neuropsychiatric symptoms in patients with Parkinson s disease and dementia: frequency, profile and associated. care giver stress, J. Neurol. Neurosurg. Psychiatry 2007; 78: 3642. 13. Steele C, Rovner B, Chase GA and Folstein M. Psychiatric problems and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry. 1990; 147: 104951. 14. Mangone CA, Sanguinetti RM, Baumann PD et al. Influence of feelings of burden on the caregiver's perception of the patient's functional status. Dementia. 1993; 4: 28793. 15. Choi SH et al, The Korean version of the Neuropsychiatric Inventory: A scoring tool for Neuropsychiatric Disturbance in Dementia Patient, J Korean Med Sci. 20000; 15: 60915. 16. Gauthier S, Wirth Y and Mobius HJ. Effects of memantineon behavioural symptoms in Alzheimer s disease patients: an analysis of the Neuropsychiatric Inventory () data of two randomised, controlled studies, Int J Geriatr Psychiatry. 2005; 20: 459 64. 17. Abdollahpour I, Nedjat S, Noroozian M, Golestan B and Majdzadeh R. Development of a Caregiver Burden Questionnaire for the Patients with Dementia in Iran, Int J Prev Med. 2010; 1: 233241. 18. Neuropsychiatric Inventory, Available at: www.pddoc.org/linkclick.aspx?fileticket= lc2rkzvhdt0%3d Accessed: 15/12/2009 19. Karlikaya G, Yukse G and Varlibas F. Caregiver Burden In Dementia: A Study In The Turkish Population. The Internet Journal of Neurology. 2005; 4. 20. Papastavrou E, Kalokerinou A, Savvas S. Papacostas, Tsangari H and Sourtzi P. Caring for a relative with dementia: family caregiver burden. journal of Advanced Nursing. 58; 5: 446 57. 21. Ana MG, Mingot M, Gomez X, Soler T, Torres G, Sacristan O, et al. Use of the Zarit Scale for assessing caregiver burden and collapse in caregiving at home in dementias. Int. J. Geriatr. Psychiatry 2007; 22: 957 62. 22. Annerstedt L, Elmstahl S, Ingvad B and Samuelsson SM. Family Caregiving in Dementia:An Analysis of the Caregiver's Burden and the "BreakingPoint" When Home Care Becomes Inadequate,Scand J Public Health. 2000; 28: 2331.

8 / Abstracts Iranian Journal of Epidemiology 2011; 7(2): 5159. Original Article Psychiatric Symptoms in Patients with Dementia: Prevalence and their Relationship with Caregiver Burden Abdollahpour I 1, Noroozian M 2, Nedjat S 3, Majdzadeh R 4 1 Master of epidemiology, Boukan Health Network. Urmia University of Medical Science, PhD Candidate in Epidemiology, Epidemiology and Biostatistics Department of Public Health School, Tehran University of Medical Sciences, Tehran, Iran 2 Associate Professor of Neurology, Tehran University of Medical Science, Tehran, Iran 3 Epidemiology and Biostatistics Department of Public Health School, Knowledge Utilization Research Center, Tehran University of Medical Sciences, Tehran, Iran 4 Professor, Epidemiology and Biostatistics Department of Public Health School, Knowledge Utilization Research Center, Tehran University of Medical Science, Tehran, Iran Corresponding author: Abdollahpour I., ebrahemen@gmail.com Background & Objectives: Although it is important to study the association between caregiver burden and individual with dementia, a little has been paid attention to this issue in Iranian population therefore the aim of study was to investigate the frequency of psychiatric symptoms and patients with dementia and caregiver burden associated with individual with dementia. Methods: In this study 84 patients who had referred to Iran Alzheimer s Association, along with their caregivers were included in our study. Iranian Version of Caregiver Burden and questionnaires were employed. Factors affecting factors on burden was analyzed by multivariate linear regression. Results: Our findings showed that there was at least one psychiatric disorder in all patients. Among all psychiatric symptoms delusion and elation had the highest and lowest rates with 39.3 and 2.4 percentages, respectively. Linear regression indicated that indifference and irritability symptoms were the effective psychiatric symptoms on the amount of burden placed on the caregivers. Conclusion: The symptom frequency of irritability and other symptoms showed a statistically significant positive correlation with caregiver's D score. These findings suggest that improvement of treatments for delusions, irritability among dementia patients may reduce caregiver burden. Keywords: Dementia, Psychiatric symptoms, Caregiver burden, Prevalence, Iran