MANAGEMENT OF ASTHIVAHA SROTODUSHTI WSR TO OSTEO- ARTHRITIS AN APPRAISAL

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Review Article International Ayurvedic Medical Journal ISSN:2320 5091 MANAGEMENT OF ASTHIVAHA SROTODUSHTI WSR TO OSTEO- ARTHRITIS AN APPRAISAL NR NavodayRaju 1, S Deepika 2, Kekuda TRPrashanth 3 1,2 PG Scholar, 3 Associate Professor, Department of KriyaShareera, SDM College of Ayurveda and Hospital, Hassan, Karnataka, India ABSTRACT In Ayurveda internal transportation system of the body is explained by the concept of Srotas,which means the structure through which Sravana takes place. Vata being aggravated will vitiate the AsthivahaSrotas leading to the degeneration of the joints including articular cartilage and subchondral bone because of Asthivaha Srotodushti leading to Osteo-arthritis. Osteoarthritis is the disease of Asthivahasrotass featured with symptoms like breaking pain, edema and limitamen and 18% in tion of movements of the joints etc., with worldwide prevalence of 9.6% in women at the age of 60 years. It is the highest ranking disease among Musculo-skeletal can be adopted for the better management of this ailment. diseases. Tikta Samyukta Ksheera SarpiBasti Key words: Asthi, Asthivaha, Srotas, Dushti, Osteoarthritis, Basti, TiktaKsheeraBasti, Calcium. INTRODUCTION In Ayurveda internal transportation system of the body is explained by the conmeans the cept of Srotas(channel) which structure through which Sravana (i.e. Ooz- ing) takes place. Among all the Srotas, As- thivahasrotas is having its own importance with its susceptibility to get vitiated (Dushti) and giving rise to different disorders. Oswith world- teoarthritis is one among them wide prevalence of 9.6% in men and 18% in women at the age of 60 years. It is the high- diseases.srotodushti(vitiation) is of four est ranking disease among Musculo-skeletal types like Atipravrutti, Sanga, VimargaGabeing aggra- mana and Siragranthi. Vata vated at the age of 50-60 years will cause AsthivahaSrotodushti leading to the degene- including ration of the joints (Asthidhatu) articular cartilage and subchondral bones (Osteoarthritis). Ashraya- AshrayeebhavaSambandha of Vata and Asthidhatu having its own role in the disease causation. AsthivahaSrotodushtiLakshanas includes AsthiVriddhi and KshayaLakshanas. We can observe the similarities in the symptoms of Osteoarthritis with AsthivahaSroto- inflamma- dushtilakshanas like heaviness, tion in the joints, pain, and deformity in the joints and crepitus in movements. So Os- as a Vikaraof teoarthritis can be considered AsthivahaSrotodushti and treatment prin- like ciples mentioned for AsthidhatuVikaras Panchakarma procedures especially Tikta- can be adopted Samyukta KsheeraSarpiBasti for better management. The mode of action of drug in this procedure can be interpreted by using the concepts like Panchamahabhu- Dravyasused for the procedure with their tas, Ashraya- AshrayeebhavaSambandha, Gunas(attributes) and concept of Kalaa (like AsthidharaKalaa is nothing but Pureeshad-

918 harakalaa). In contemporary science also it is proved that intestines only regulate the absorption of calcium which is very essential for healthy bones. In this way Osteoarthritis can be better managed with Ayurvedic approach in a scientific manner. MATERIALS AND METHODS Review of literature of concepts related to AsthivahaSrotodushtiVikara, Osteoarthritis and analysis and interpretation of probable mode of action of TiktaSamyuktaKsheera- SarpiBasti. AIMS AND OBJECTIVES: 1.To interpret symptoms of AsthivahaSrotodushti with Osteo-Arthritis. 2. To analyze critically the Probablemode of action of TiktaSamyuktaKsheeraSarpiBasti for the management. LITERATURE REVIEW Asthidhatu: It is the fifthdhatu(tissue) among the Saptadhatumentioned by the Acharyas,formed frommedodhatu. Dehadharana(supporting the body) is the prime function of Asthidhatu. It can be comparable with osseous tissues i.e.bones, cartilages and teeth. AsthidhatuVriddhi leads to the excessive growth of bones and teeth and over growth (one above the other). Its Kshaya causes pricking pain in the bones, falling of tooth, nail and hairs. Asthi becomes so porous and get fractured even with little strain or accidents 1. Srotas: Internal transportation system of the body is explained by the concept of Srotas which cannot be compared exactly with any modern terminology. The term Srotas is derived from the main Sanskrit root Srusrawane which means the structure to exudate, to ooze, to filter and to permeate 2. It is neutral in gender. The Srotas are numerous but for the convenience and easy understanding AcharyaCharakahas described 13 types of Srotaswhich includes Prana, Udaka, Anna, Rasa, Rakta, Mamsa, Medo, Asthi, Majja, Shukra, Mutra, Sweda and Pureeshavahasrotas 3.But AcharyaSushrutahas described 11 pairs of Srotas excludingasthi,majja, Swedavahasrotasand adding Artavavahasrotas 4. Asraya- AshrayeebhavaSambandha: Vata- Dosha resides in the Asthidhatu, Pitta Dosha resides in the Rakthadhatu and Kapha- Dosha in the rest of the Dhatu.WhenDosha residing in a Dhatuincreases, the particular Dhatuwill also get increased. But this rule is just reverse in case of Vataand Asthii.e. the aggravated Vatawill cause the depletion of Asthidhatu 5. Asthivahasrotas: Channels of transportation for Asthaayi (Poshaka, Sukshma)Asthidhatu to their destination are Asthivahasrotas 6. According to contemporary view, Asthivahasrotas may be compared with nutrient artery of bone which carries essential nutrients to it. Charaka mentionsmulasthanaof AsthivahasrotasasMedasand Jaghana(groin region/flat pelvic bones). Medas is the fourth Dhatu and Asthi is formed fromasthiposhakamshaof Meda i.e. AsthaayiMedodhatu.Nutrition of Asthidhatu depends on proper nourishment of Medodhatu. SoMeda is the Mulasthanaof Asthi. Any abnormality in structure and function ofjaghana i.e. groin or pelvic regions leads to disturbance in the upright position of living body because they are the pillars of the body, doing the Dharana Karma, which is the primefunction of Asthidhatu; so,medasand Jaghana are rightly said as root of Asthivahasrotas 7. AsthivahaSrotodushti: Components of the body cannot undergo any change i.e. Kshayaor Vriddhi without any involvement of thesrotas 8.Srotodushti i.e. deformity or malfunctioning will takes place when vi-

919 tiated Dosha get localized in the Srotas.Atipravrutti(Excessive flow), Sanga(Obstruction), Siragranthi(Extra growths) and VimargaGamana(Reverse flow) are the types of Srotodushti 9.Exercise, involving excessive irritation and rubbing of bones and intake of Vata provoking food will lead to Sanga and VimargaGamana types of Srotodushti in Asthivahasrotas.It will lead to Vriddhi(Adhyasthi, Adhidantha,Danta,AsthiBheda) or Kshaya(Shoola, Vivarnatha of Dantha and Asthi, deformity of Kesha, Loma, Nakha and Smasru)of Asthidhatu 10. Khavaigunya in SandhiSthana leads to accumulation of Vata (Sthana Samshraya). At this stage, Dosha Dushya Sammurchhana takes place leading to destructive changes in Asthi and diminution of SleshakaKapha, further leading to appearance of symptoms of SandhigataVata like the joint feels as an air filled bag (VataPurnadritisparsha) and pain during flexion and extension (Akunchana- PrasaranaPravrittiSavedana) 11. OSTEOARTHRITIS VIS-À-VIS SAND- HIGATA VATA Osteoarthritis is a condition of synovial joints characterized by focal loss of articular hyaline cartilage with proliferation of new bone and remodeling of joint structure. It is the most common type of arthritis. Cartilages are slippery tissues covering ends of bones and allow bones to glide one over another. After cartilage degeneration, bones rub together causing pain, swelling and loss of motion of joints or limitation of movements resulting in joint stiffness which may be caused by synovitis with effusionor osteophyte formation(as in Heberden s nodes). Deep achy pain that worsens with use, morning stiffness, crepitus and limitation of range of movement are characteristic features 12. We can observe the similarities in the features of Osteoarthritiswith AsthivahaSrotodushtilikeheaviness, inflammation in the joints, pain, crepitation in movements and deformity in the joints. So it can be considered as AsthivahaSrotodushtiVikara. TREATMENT PRINCIPLE Considering as an AsthivahaSrotodushtiVikara, treatment mentioned for AsthiDhatuVikaras i.e. TiktaSamyuktaKsheeraSarpiBastican be adopted for Osteoarthritis. DISCUSSION Osteoarthritis is an Asthivaha Srotodushti Vikara, X-ray findings in Osteoarthritis like joint space narrowing, subchondralsclerosis, formation of osteophytes and subchondral cysts also gives us an idea about AsthivahaSrotodushtiLakshanas. A number of analgesics, antiinflammatory drugs as well as steroids are available for it. However, a permanent relief is not provided by any of these and the same is still under research. Ayurveda can provide such treatment which controls pathogenesis and prevent the patient from developing complications and surgical treatment. Asthivaha SrotodushtiVyadhi can be treated by Basti procedure of Panchakarma by taking TiktaSamyuktaKsheeraBasti added with Sarpi 13. For the purpose of interpreting the probable mode of drug action four concepts are utilized here under: Concept of Dosha Concept of PureeshadharaKalaa Concept ofguna Concept of Panchamahabhutas Calcium metabolism in Large intestines

PROBABLE MODE OF DRUG AC- TION: Vata is the dominant involved Dosha in the causation of Osteoarthritis so Basti (Anuvasana) is the specific choice of treatment 14. Importance of Basti in this context also can be interpreted using the concept of ofkalaa. PureeshadharaKalaa and AsthidharaKalaa are one and the same 15 i.e. if PureeshadharaKalaa is nourished (by Basti) thereby it will nourish the AsthidharaKalaa (Asthidhatu). Hence Basti is the treatment mentioned in the management of Asthidhatu Vikaras. A drug which is having Snigdha, Shoshana and Khara Gunas only can nourish the Asthidhatu but unfortunately no single Dravya is available having all these 3 properties so Acharyas explained to use the combination of Dravyas having all three properties to act at Dhatu level by the combination of Tikta Rasa Dravya, Ksheera and Sarpi. Tikta rasa havingkhara, ShoshanaGunas and SnigdhaGuna is the quality of Ksheera and Sarpi, Which will aid in the successful nourishment of Asthidhatu 16. Panchabhoutikatwa of Tikta Rasa is Vayu and Akashabecause of which it can easily penetrate through and capable of reaching deeper Dhatu i.e. Asthidhatu having similar Composition and it will act as a medium for Ksheera and Sarpi to reach Asthi thereby nourishing it 17. Even Ksheera and Sarpi surely have their role in pacifying the VataVardhaka property of Tikta Rasa 18. Calcium metabolism which is very essential for the rigidity of bones is regulated by the intestine by adjusting the absorption of calcium 19. Cow milk composed of maximum Calcium which is used in TiktaSamyuktaKsheeraSarpiBasti procedure. Calcium is being absorbed both actively and passively in the Large intestine there by expected to help the healthy growth and rejuvenation of osseous tissue 20. CONCLUSION Osteoarthritis which can be comparable with Asthivahasrotodushti Janita Vyadhi which can be better managed with Ayurvedic special modality treatment Basti i.e. Tikta Samyukta Ksheera Sarpi Basti. REFERENCES 1. Paradakara HSS. AshtangaHrudaya with : ChaukambhaOrientalia; 2005. p. 184-85. 2. Sharma RK and Das B. Agnivesa scharakasamhita based on Cakrapanidutta s 2009.Vol 1 p.595. 3. Sharma RK and Das B. Agnivesa scharakasamhita based on Cakrapanidutta s 2009.Vol 2 p.173. 4. Sharma PV.SusruthaSamhita Sutra Sthana.Reprint ed.varanasi:chaukhambhavisvabharati; 2010.p.220. 5. Paradakara HSS. AshtangaHrudaya with :ChaukambhaOrientalia; 2005. p. 186-87. 920

921 6. Kumar AK, PrabhaAS.Compendium views on SrotoShareera. 1 st ed. Varanasi: Chaukhambha Ayurveda Pratishthan;2008.p. 57-8. 7. Sharma RK and Das B. Agnivesa scharakasamhita 2009.Vol 2 p.174. 8. Kumar AK, PrabhaAS.Compendium views on SrotoShareera. 1 st ed. Varanasi: Chaukhambha Ayurveda Pratishthan;2008.p. 57-8. 9. Sharma RK and Das B. Agnivesa scharakasamhita 2009.Vol 2 p.174-76. 10. Paradakara HSS. AshtangaHrudaya with :ChaukambhaOrientalia; 2005. p. 184-5. 11. Sharma RK and Das B. Agnivesa scharakasamhita 2009.Vol 5 p.30. 12. Golwalla AF and Golwalla SA. Golwalla s Medicine.23 rd ed.mumbai:national;2011.p. 900. 13. Sharma RK and Das B. Agnivesa scharakasamhita 2009.Vol 1 p.579. 14. Paradakara HSS.AshtangaHrudaya with :ChaukambhaOrientalia; 2005. p. 211-12. 15. Acharya JT. Sushruta Samhita with Nibandha Sangraha commentry of Dalhanacharya. Reprint ed. Varanasi: Chaukhamba Sanskrit Sansthan;2013. p. 574. 16. Paradakara HSS. AshtangaHrudaya with Sarvangasundara commentary of Arunadatta :ChaukambhaOrientalia; 2005. p. 187-88. 17. Sharma RK and Das B. Agnivesa scharakasamhita 2009.Vol 1 p.463. 18. Paradakara HSS. AshtangaHrudaya with Sarvangasundara commentary of Arunadatta :ChaukambhaOrientalia; 2005. p. 67-68, 73-4. 19. Chaudhuri SK. Concise medical physiology, Reprint 2 nd ed.calcutta: New Central Book Agency; 1994.p.297. 20. Felix B,Danielle P. Nutrional Aspects of Calcium Absorption. JN.1999 Jan 1[cited 2015 Feb 22]; 129(1): about 4 pages.available from: http//intljn.nutrition.org. CORRESPONDING AUTHOR Dr. N R NavodayRaju PG Scholar, Department of KriyaShareera, SDM College of Ayurveda and Hospital, Hassan, Karnataka, India Email:drnrnraju@gmail.com Source of support: Nil Conflict of interest: None Declared