Art. no..7150.095 Page 1 of 9 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier 1.2. Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture Ready for use staining solution for the automated serum-albumin-electrophoresis. 1.3. Details of the supplier of the safety data sheet Company name: Street: Place: Post-office box: SARSTEDT AG & Co. Sarstedtstraße 1 D-515 Nümbrecht 1220 D-5152 Nümbrecht Telephone: +49 (0)2293 / 305-0 Telefax:+49 (0)2293 / 305-2470 e-mail: info@sarstedt.com Contact person: Dr. Dagmar Flach Telephone: +49 (0)2293 / 305-4500 Jochen Hoffmann e-mail: sicherheitsdatenblatt@sarstedt.com Internet: Responsible Department: 1.4. Emergency telephone number: SECTION 2: Hazards identification www.sarstedt.com R & D Center 2.1. Classification of the substance or mixture Poison Center in Bonn (Germany): +49 (0)22 / 19240 Indications of danger: Xi - Irritant, N - Dangerous for the environment R phrases: Irritating to eyes, respiratory system and skin. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Classification according to Regulation (EC) No. 1272/200 [CLP] Hazard categories: Skin corrosion/irritation: Skin Irrit. 2 Serious eye damage/eye irritation: Eye Irrit. 2 Specific target organ toxicity - single exposure: STOT SE 3 Hazardous to the aquatic environment: Aquatic Chronic 2 Hazard Statements: Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Toxic to aquatic life with long lasting effects. 2.2. Label elements Hazardous components which must be listed on the label trichloroacetic acid Signal word: Pictograms: Warning GHS07-GHS09
Art. no..7150.095 Page 2 of 9 Hazard statements H315 H319 H335 H411 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Toxic to aquatic life with long lasting effects. Precautionary statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash hands thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P20 Wear protective gloves/protective clothing/eye protection/face protection. P302+P352 IF ON SKIN: Wash with plenty of water. P321 Specific treatment (see Remarks on this label). P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P312 Call a POISON CENTER/doctor if you feel unwell. P305+P351+P33 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P391 Collect spillage. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container to waste disposal site according to legal regulations. 2.3. Other hazards Due to the low ph value the solution is irritating to skin and may cause severe eye demage. SECTION 3: Composition/information on ingredients 3.2. Mixtures Chemical characterization Dark red, aqueous, strong acidic solution ready for use to stain the protein fractions of the automated serum-protein-electrophoresis. Besides trichloracetic acid the solution contains arylsulphonic acid and the protein dye Ponceau S. Hazardous components EC No CAS No Index No REACH No Chemical name Classification according to Directive 67/54/EEC Classification according to Regulation (EC) No. 1272/200 [CLP] Quantity 200-927-2 76-03-9 607-004-00-7 trichloroacetic acid Full text of R-, H- and EUH-phrases: see section 16. C - Corrosive, N - Dangerous for the environment R35-50-53 Skin Corr. 1A, Aquatic Acute 1 (M-Factor = 1), Aquatic Chronic 1 (M-Factor = 1); H314 H400 H410 1 - < 5 % SECTION 4: First aid measures
4.1. Description of first aid measures After inhalation Provide fresh air. Medical treatment necessary. Safety Data Sheet Art. no..7150.095 Page 3 of 9 After contact with skin IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. If skin irritation occurs: Get medical advice/attention. After contact with eyes If product gets into the eye, keep eyelid open and rinse immediately with large quantities of water, for at least 5 minutes. Subsequently consult an ophthalmologist. After ingestion Rinse mouth immediately and drink plenty of water. Call a physician immediately. 4.2. Most important symptoms and effects, both acute and delayed Irritating to eyes, respiratory system and skin. 4.3. Indication of any immediate medical attention and special treatment needed After skin contact: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. After eye contact: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. After swallowing: Rinse mouth immediately and drink plenty of water. SECTION 5: Firefighting measures 5.1. Extinguishing media Suitable extinguishing media Co-ordinate fire-fighting measures to the fire surroundings. 5.2. Special hazards arising from the substance or mixture The product itself does not burn. 5.3. Advice for firefighters Wear a self-contained breathing apparatus and chemical protective clothing. Full protective suit. Additional information Suppress gases/vapours/mists with water spray jet. Collect contaminated fire extinguishing water separately. Do not allow entering drains or surface water. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures Provide adequate ventilation. Do not breathe gas/fumes/vapour/spray. Avoid contact with skin, eyes and clothes. Wear personal protection equipment. 6.2. Environmental precautions Do not allow to enter into surface water or drains. If product reaches waters, soil or sewage systems please inform the responsible authorities. 6.3. Methods and material for containment and cleaning up The product needs to apply neutralizing agents before draining to wastewater treatment plants. Absorb with liquid-binding material (e.g. sand, diatomaceous earth, acid- or universal binding agents). Wear protective gloves. Treat the recovered material as prescribed in the section on waste disposal.
6.4. Reference to other sections See also section and 13. SECTION 7: Handling and storage 7.1. Precautions for safe handling Safety Data Sheet Art. no..7150.095 Page 4 of 9 Advice on safe handling If handled uncovered, arrangements with local exhaust ventilation have to be used. Avoid formation of aerosol. Do not breathe gas/fumes/vapour/spray. 7.2. Conditions for safe storage, including any incompatibilities Requirements for storage rooms and vessels No special requiremets on store rooms. Keep container tightly closed. Advice on storage compatibility Keep away from food. Do not store together with: Strong oxidizing substances. 7.3. Specific end use(s) Ready for use staining solution for the automated serum-albumin-electrophoresis. SECTION : Exposure controls/personal protection.1. Control parameters.2. Exposure controls Appropriate engineering controls If handled uncovered, arrangements with local exhaust ventilation have to be used. Do not breathe gas/fumes/vapour/spray. Protective and hygiene measures Remove contaminated, saturated clothing immediately. Protect skin by using skin protective cream. After work, wash hands and face. When using do not eat or drink. Eye/face protection Wear tightly sealed safety glasses. Hand protection The quality of the protective gloves resistant to chemicals must be chosen as a function of the specific working place concentration and quantity of hazardous substances. Skin protection Personal protective equipment is to be chosen depending on concentration and quantity of the hazardous materials and in consideration of the workplace. The chemical resistance of the protective equipment shall be clarified with the supplier. Respiratory protection Wear breathing apparatus if exposed to vapours/dusts/aerosols. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state: Colour: Odour: liquid dark red characteristic ph-value (at 25 C): < 1,0 Test method Changes in the physical state Melting point:
Initial boiling point and boiling range: Flash point: Flammability Solid: Gas: Lower explosion limits: Upper explosion limits: Auto-ignition temperature Solid: Gas: Vapour pressure: Density (at 20 C): Water solubility: Solubility in other solvents Partition coefficient: Vapour density: Evaporation rate: 9.2. Other information none SECTION 10: Stability and reactivity 10.1. Reactivity 10.2. Chemical stability Safety Data Sheet Solution is stable at room temperature for at least 4 years. Art. no..7150.095 Page 5 of 9 100 C 1,03 g/cm³ completely miscible 10.3. Possibility of hazardous reactions It is pointed out that strong acidic solutions should not be brought in contact with concentrated lyes or amines (strong formation of heat) or with sodium hypochlorite solutions (formation of chlorine gas). 10.4. Conditions to avoid 10.5. Incompatible materials 10.6. Hazardous decomposition products SECTION 11: Toxicological information 11.1. Information on toxicological effects Acute toxicity Experimentally determined, toxicological values of the product itself are not available. However, the following theoretical value can be determined from the values and concentrations of the pure components: LD 50 oral (rat): approx. 20.000 mg/kg
Art. no..7150.095 Page 6 of 9 CAS No Chemical name Exposure routes 76-03-9 trichloroacetic acid oral Method Dose Species Source LD50 3320 mg/kg Rat (IUCLID) Irritation and corrosivity Causes skin irritation. Causes serious eye irritation. Irritating to eyes. Following inhalation: Lung irritation. Coughing. shortage of breath. After skin contact: Irritant. Sensitising effects STOT-single exposure May cause respiratory irritation. Severe effects after repeated or prolonged exposure Carcinogenic/mutagenic/toxic effects for reproduction Aspiration hazard Additional information on tests The classification was carried out according to the calculation method of the Preparations Directive (1999/45/EC). SECTION 12: Ecological information 12.1. Toxicity Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 12.2. Persistence and degradability 12.3. Bioaccumulative potential Partition coefficient n-octanol/water CAS No Chemical name 76-03-9 trichloroacetic acid 1,33 12.4. Mobility in soil 12.5. Results of PBT and vpvb assessment 12.6. Other adverse effects Further information Do not allow to enter into surface water or drains. The classification was carried out according to the calculation method of the Preparations Directive (1999/45/EC). SECTION 13: Disposal considerations 13.1. Waste treatment methods Log Pow
Art. no..7150.095 Page 7 of 9 Advice on disposal Do not allow to enter into surface water or drains. Dispose of waste according to applicable legislation. Contaminated packaging Non-contaminated packages may be recycled. Handle contaminated packages in the same way as the substance itself. SECTION 14: Transport information Land transport (ADR/RID) 14.1. UN number: UN 2564 14.2. UN proper shipping name: 14.3. Transport hazard class(es): 14.4. Packing group: Hazard label: TRICHLOROACETIC ACID SOLUTION III Classification code: C3 Limited quantity: 5 L Transport category: 3 Hazard No: Tunnel restriction code: 0 E Inland waterways transport (ADN) 14.1. UN number: UN 2564 14.2. UN proper shipping name: 14.3. Transport hazard class(es): 14.4. Packing group: III Hazard label: TRICHLOROACETIC ACID SOLUTION Classification code: Limited quantity: Marine transport (IMDG) C3 5 L 14.1. UN number: UN 2564 14.2. UN proper shipping name: 14.3. Transport hazard class(es): 14.4. Packing group: Hazard label: TRICHLOROACETIC ACID SOLUTION III Special Provisions: Limited quantity: EmS: Air transport (ICAO) 223 5 L F-A, S-B
Art. no..7150.095 Page of 9 14.1. UN number: UN 2564 14.2. UN proper shipping name: TRICHLOROACETIC ACID SOLUTION 14.3. Transport hazard class(es): 14.4. Packing group: III Hazard label: Special Provisions: Limited quantity Passenger: IATA-packing instructions - Passenger: IATA-max. quantity - Passenger: IATA-packing instructions - Cargo: IATA-max. quantity - Cargo: 14.5. Environmental hazards ENVIRONMENTALLY HAZARDOUS: A3 A03 1 L yes 52 5 L 56 60 L 14.6. Special precautions for user none 14.7. Transport in bulk according to Annex II of MARPOL73/7 and the IBC Code The mixture is not intended for bulk haulage. SECTION 15: Regulatory information 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture National regulatory information Water contaminating class (D): 15.2. Chemical safety assessment 2 - water contaminating Chemical safety assessments for substances in this mixture were not carried out. SECTION 16: Other information Changes General revision. Relevant R-phrases (Number and full text) 35 Causes severe burns. 50 Very toxic to aquatic organisms. 53 May cause long-term adverse effects in the aquatic environment. Relevant H- and EUH-phrases (Number and full text) H314 Causes severe skin burns and eye damage. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H400 Very toxic to aquatic life. H410 Very toxic to aquatic life with long lasting effects. H411 Toxic to aquatic life with long lasting effects.
Art. no..7150.095 Page 9 of 9 Further Information The information contained herein is based on the present state of our knowledge. It characterizes the product with regard to the appropriate safety precautions. It does not represent a guarantee for the properties of the product. (The data for the hazardous ingredients were taken respectively from the last version of the sub-contractor's safety data sheet.)