International Society of Intraoperative Neurophysiology (ISIN)

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7 th Congress and Educational Course November 1-3, 2018 Madrid, Spain Educational Course: Brain surgery neuromonitoring November 1-3, 2018 Day 1, November 1 12:00 13:00 Registration 13.00-13.20 Welcome and Introduction: Local organizing committee Beatriz Arranz and Julio Prieto, Spain ISIN President Francisco Soto, Chile Course Overview Javier Urriza, Spain ISIN Education Committee Page 1 of 6 18-April-25

Day 1, November 1 BACK TO BASICS: INTRODUCTORY COURSE ON IONM (Part I) Chairman: Vedran Deletis 13.20-13.45 (25'): Basic principles of neurophysiology Isabel Fernandez-Conejero, Spain 13.45-14.15 (30'): Safety in the OR Jay Shils, US 14.15-14.40 (25'): Anesthesia 14.40-14.50 (10'): Discussion 14.50-15.15 (25'): MEP & CoMEP Francisco Soto, Chile 15.15-15.40 (25'): SEP Elif Aydinlar, Turkey 15.40-16.05 (25'): EEG David MacDonald, Saudi Arabia 16.05-16.15 (10'): Discussion 16.15-16.45 (30'): Coffe break BACK TO BASICS: INTRODUCTORY COURSE ON IONM (Part II) Chairman: Sedat Ulkatan 16.45-17.05 (20'): EMG Julian Prell, Germany 17.05-17.25 (20'): Reflexology Maria Tellez, US 17.25-17.45 (20'): BAER Charles Dong, Canada 17.45-18.05 (20'): VEP Javier Urriza, Spain 18.05-18.30 (25'): Mapping techniques Beatriz Arranz, Spain 18.30-18.45 (15'): Discussion 18.45-19.30 (45'): Magistral lecture 19.30-21.30 (2h): Welcome reception Social event ISIN Education Committee Page 2 of 6 18-April-25

Day 2, November 2 International Society of Intraoperative Session I: Vascular brain surgery TALKING ABOUT ANATOMY --- Chairman: Karl Kothbauer 8.00-8.30 (30'): Functional vascular anatomy Olga Mateo, Spain TALKING ABOUT SURGERY --- Chairman: Karl Kothbauer 8.30-9.00 (30 ): Surgery of intracranial aneurysms & AVM Kunihiko Kodama, Japan 9.00-9.25 (25'): Surgery of carotid endarterectomy 9.25-9.35 (10'): Discussion TALKING ABOUT NEUROMONITORING --- Chairman: Francesco Sala 9.35-10.05 (30'): Neuromonitoring in intracranial aneurysms & AVM Andrea Szelènyi, Germany 10.05-10.35 (30'): Neuromonitoring in carotid endarterectomy Michael Malcharek, Germany 10.35-11.05 (30'): Neuromonitoring in endovascular procedures Sedat Ulkatan, US 11.05-11.20 (15'): Discussion 11.20-11.50 (30'): Cofee break & exhibitors Session II: Epilepsy surgery TALKING ABOUT ANATOMY --- Elif Aydinlar 11.50-12.20 (30'): Seizures semiology and new classification Gea Drost, The Netherlands TALKING ABOUT SURGERY --- Elif Aydinlar 12.20-12.50 (30'): Epilepsy surgery TALKING ABOUT NEUROMONITORING --- Elif Aydinlar 12.50-13.20 (30'): Neuromonitoring of epilepsy surgeries David MacDonald 13.20-13.30 (10'): Discussion 13.30-14.30 (1h): Lunch & exhibitors 14.30-15.15 (45'): DG - Rotation 1 15.15-16.00 (45'): DG - Rotation 2 16.00-16.30 (30'): Coffe break & exhibitors 16.30-17.15 (45'): DG - Rotation 3 17.15-18.00 (45'): DG - Rotation 4 Session III: Discussion groups* (Part I) Social programme ISIN Education Committee Page 3 of 6 18-April-25

Day 3, November 3 Session I: Brain tumor surgery TALKING ABOUT ANATOMY --- Chairman: Jeff Arle 8.00-8.30 (30'): Functional anatomy of cortical areas & tracts Lanjun Guo, US TALKING ABOUT SURGERY --- Chairman: Jeff Arle 8.30-8.55 (25'): Surgery of tumors in motor areas Klaus Novak, Austria 8.55-9.20 (25'): Tumors in the insula & deep brain Karl Kothbauer, Switzerland 9.20-9.45 (25'): Brain surgery in children Franceso Sala 9.45-10.15 (30'): Awake surgeries Andreu Gabarros, Spain 10.15-10.30 (15'): Discussion 10.30-11.00 (30') Cofee break & exhibitors TALKING ABOUT NEUROMONITORING --- Chairman: Sedat Ulkatan 11.00-11.25 (25'): VEP monitoring Kunihiko Kodama, Japan 11.25-11.55 (30'): Technical aspects of electrical cortical stimulation Jay Shils, US 11.55-12.20 (25'): MEP monitoring under general anesthesia Kyung Park, South Korea 12.20-12.35 (15'): Discussion 12.35-13.00 (25') Cortical Motor and sensory mapping under general anesthesia Isabel Fernendez-Conejero, Spain 13.00-13.20 (20') Subcortical mapping under general anesthesia Kathleen Seidel, Switzerland 13.20-13.30 (10') Discussion 13.30-14.30 (1h) Lunch & exhibitors Session II: Discussion groups* (Part II) 14.30-15.40 (40'): DG - Rotation 5 15.45-16.25 (40'): DG - Rotation 6 16.25-16.55 (30'): Coffe break & exhibitors 16.55-17.35 (40'): DG - Rotation 7 17.40-17.20 (40'): DG - Rotation 8 17.20-17.30 (10'): Break ISIN Education Committee Page 4 of 6 18-April-25

17.30-18.00 (10'): Course evaluation (7'): Adjourn: Local organizing committe (7'): Presentation of 8 th Congress and Educational Course 2019 (5'): Adjourn: ISIN President Final remarks ISIN Education Committee Page 5 of 6 18-April-25

Discussion groups distribution DG Topic Faculty 1 Set-up of brain tumor surgeries Ulkatan and Urriza 2 Technical parameters and troubleshooting Shils, Drost and Arranz 3 Anesthesia for optimal brain surgery Malcharek and Local 4 Monitoring vascular procedures Szelenyi, Perez-Fajardo and Kodama 5 Monitoring epilepsy surgery MacDonald and Simon 6 Monitoring brain tumor surgery Seidel, Aydinlar and Soto 7 Monitoring awake brain surgery Guo and Fernandez-Conejero 8 Considerations for pediatric brain surgery Kothbauer & Sala Rotations Day 1 Day 2 1 2 3 4 5 6 7 8 DG1 A B C D E F G H DG2 B C D E F G H A DG3 C D E F G H A B DG4 D E F G H A B C DG5 E F G H A B C D DG6 F G H A B C D E DG7 G H A B C D E F DG8 H A B C D E F G ISIN Education Committee Page 6 of 6 18-April-25