Designer drugs and road safety in Japan

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TECHNICAL CONSULTATION ON DRUG USE AND ROAD SAFETY WHO/HQ, GENEVA, SWITZERLAND, SALLE C 17 18 DECEMBER 2014 Designer drugs and road safety in Japan Kazuko Okamura National Research Institute of Police Science

1. Background 2. What is designer drugs? 3. Car crashes under the influence of designer drug 4. Challenge for road safety

Governmental organisations in Japan Cabinet Office Ministry of Health National Police 7 Regional Narcotic Agents National Institute Of Health Sciences National Research Institute of Police Science Research Forensic investigation Training 47 Prefecture Police Dep. Forensic laboratory National Center for Neurology and Psychiatry Ministry of Transport

1.1 Road fatalities 12 10 8 6 4 2 0 Road fatalities per 100 000 population (2012) in selected IRTAD member countries * * ** * 2013, ** 2011 About half fatalities are older people (pedestrians, cyclists, etc.) Low % of alcohol impaired fatal crashes (6%)

1.2 Illicit drugs and psychotropic medicine Lower prevalence of illicit drug use 84% of illicit drug related criminal conviction is due to methamphetamine, followed by cannabis (12%). National Police Agency (2014) Designer drugs NOT included. Lower prevalence of psychotropic medicine except for benzodiazepines (BZD)

Annual prevalence (%) of illicit drug use among the population aged 15 64 Cannabis Amphetamine type stimulants ʺEcstasyʺ Cocaine Opioids Opiates 0.6 0.6 0.5 0.2 0.7 0.03 0.8 0.3 0.7 0.3 0.4 0.5 1.3 0.9 1.6 4.0 5.2 10.8 East/Southeast Asia North America Europe 0 5 10 United Nations Office on Drugs and Crime (2012) World drug report.

Lifetime prevalence (%) of illicit or licit drug use among the Japanese population aged 15 64 Cannabis 1.1 Methamphetamine 0.5 ʺEcstasyʺ 0.3 Organic solvent 1.9 Designer drugs 0.4 % 0 5 10 National Center of Neurology and Psychiatry (2013) Survey on use of alcohol, tobacco, drugs and medication

Comparison of S DDD (defined daily doses for statistical purposes) per 1,000 inhabitants per day BZD (sedativehypnotics) BZD (anxiolytics) Opiod analgesics 45.8 Japan Australia Europe Americas 0 20 40 60 A reflection of inappropriate prescribing patterns and associated abuse International Narcotics Control Board (2011)

1. Background 2.What is designer drugs? 3. Car crashes under the influence of designer drug 4. Implications for road safety

2. What is designer drugs? New psychoactive substances (NPS) Contain new chemically engineered psychoactive substances designed to remain outside international control. UNODC (2012) Mimic the effects of illicit drugs and are produced by introducing slight modification to the chemical structure of controlled substances to circumvent drug control. UCODC (2013)

They are sold under names of. Bath salts, herbal incense, video cleaners, air fresheners, research chemicals, etc. and are packaged in the form of. Seeds Powders Liquids Pills/tablets + Labelled as Not for Human Consumption and sold 10 20 US dollars/euros per gram

What are they made from? Synthetic cannabinoids Effects and chemical structure similar to cannabis Synthetic cathinones Effects and chemical structure similar to illicit stimulants Ketamine Phenethylamines Piperazines Plant based substances (UNODC, 2013; Uchiyama et al., 2014)

Classification of designer drugs Compounds Herbal blends Liquids Powder Synthetic cannabinoids Synthetic cathinones Typical use sex drug rave/party Effects Downer Upper National Center for Neurology and Psychiatry (2013) Often contain more than one substances Unknown psychoactive substances

Designer drugs as a public health concern Warning from public health experts: 40% of abusers experienced acute hallucination/delusion. 60% of inpatients reported previous cannabis use. National Center for Neurology and Psychiatry (2012) Number of emergency ambulance transport after using designer drug Ministry of Internal Affairs and Communications (2014) Number of deaths after using designer drugs National Police Agency (2014)

1. Background 2. What is designer drugs? 3. Car crashes under the influence of designer drug 4. Challenges for road safety

3. Car crashes under the influence of designer drug Media coverage of a crash caused by an intoxicated man resulting in 8 death/injuries in central Tokyo (June 2014) Designer drug crashes became a focus of attention Intoxicated/impaired drivers were often found to be unconscious at the wheel hallucinated or under acute delusion

Designer drugs as a social problem Immediate policy response: transministerial emergency meeting held in July 2014 Appellation changed from quasi licit drug to dangerous drug More resources for prompt drug testing More than 1,400 substances have been scheduled (as of Dec 2014): Analog/generic system (2013 ) Emergency scheduling (2014 )

Designer drug car crashes and other criminal cases 2009 2010 2011 2012 2013 0 0 0 19 40 Number of arrests car crashes possession, use, etc. 2014 Jan June 33 0 100 200 National Police Agency (2014) Average age of the convicted is 34. 80% had no previous drug arrest records unlike meth. 62% purchased designer drugs at street shops.

Random roadside testing Per se laws Systematic post crash drug testing Drug detection on the road and driver prosecution Alcohol Yes Yes (BAC 0.03%) Only with fatal crashes (24 hours) Other impairing substances No No No Impairment based law Yes Yes Applied only when impaired driver injured others

Ratio of alcohol crashes based on impairment law to alcohol crashes based on per se law (2012) Alcohol crashes based on impairment law (n =178) 24 Per se law crashes Breath tests done at traffic controls Crashes with BAC 0.03% (n = 4,363) Breath test positive n 32,000 7

Simple estimation of drug/medication impaired driving (2012) Alcohol crashes based on impairment law (n =178) Crashes with BAC 0.03% (n = 4,363) 24 Drug/medication impaired crashes (n = 69) Crashes equivalent to BAC 0.03% Drug test positive n 12,000 24 7 Breath test positive n 32,000 7

1. Background 2. What is designer drugs? 3. Car crashes after driver taking designer drug 4. Implications for road safety

4. Implications for road safety Major policy response so far More budget allocated to speedy drug identification Tougher enforcement on retailers Publicity campaigns Response from the traffic police: Thorough criminal investigation Publicity campaigns Heavy burden for traffic criminal investigation teams to prosecute each case successfully

Conclusion Unsuspecting people may have started using designer drugs, allured by its seeming non illegal, harmless image. A series of designer drug car crashes prompted political initiatives, but this is confined to actions toward more swift drug identification and testing. This can be a good opportunity to address research needs with regard to drug prevalence on the road and its crash risk.

Thank you for your attention!