Southern African HIV Clinicians Society Conference 2018 programme subject to change 2 P a g e

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CONFERENCE PROGRAMME WEDNESDAY, 24 OCTOBER 2018 08h00 18h00 Registration OFFICIAL MEETING COMMENCES 14h00 15h30 Session 1A Adolescent cases - Teen pregnancy and breast feeding - Previously on PrEP, now pregnant. What to do? (Tshidi Sebitloane) - Teen adherence (Juliet Houghton) Session 1B Adult cases (Michelle Venter, tba) - Adherence - Mental health - STIs - Opportunistic Infections - TB - Drug Interactions Panel discussion (Gary Maartens, Yunus Moosa, Francesca Conradie) Jeremy Nel 15h30 16h00 Refreshments, exhibition and posters 16h00 17h30 Session 2: Open Session Debate: Undetectable = Untransmittable - Yes (Annemarie Wensing) - No (Graeme Meintjes) Yunus Moosa 17h40 19h00 Session 3: Opening Plenary Official conference opening Mechanism of resistance (Douglas Richman) HIV drug resistance: are we about to win the war? (John Mellors) Annemarie Wensing 19h00 21h00 Opening Cocktail Function Session 1C Skills building - Nurse cases - Cases primary healthcare, rural doctors (Ndiviwe Mphothulo, Jenny Nash) - Cases nurses (Talitha Crowley, Gloria Mthombeni) - Panel discussion: Integration; Restarting (Ndiviwe Mphothulo, Talitha Crowley, Gloria Mthombeni, Jenny Nash Gloria Maimela 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 2 P a g e

THURSDAY, 25 OCTOBER 2018 07h30 08h15 Session 4A Stock outs and medicine availability - Stop Stockouts Project - Essential medicines to add to the formulary - TB 08h20 10h15 10h15 10h30 10h30 12h00 12h00 13h30 Session 5: Plenary Session 90-90-90 - How are we doing with HIV self-screening? (Francois Venter) - How are we doing with Universal test and treat? - How are we doing with viral suppression? (Sergio Carmona) Refreshments, exhibition and posters Session 6A PrEP consult - How to administer PrEP: a typical clinical consultation (Muhangwi Mulaudzi) - How to bill PrEP coding (Siraaj Adams) - The experience of a treating physician (Eric Hefer) Moeketsi Mathe Lunch, exhibition and posters Session 6B Skills building session Infant testing - Swallowing tablets (Leon Levin) - Optimising formulations (Carol Ruffell) - The latest on infant testing, and how to access - Switching in children (Helena Rabie) - Weight and age (Helena Rabie) James Nuttall Session 4B Ethics and research - The informed consent process (Lucy Allais and Mary Carman) Session 6C Ethics and the Law - Whistle-blowing in the health-sector - Mandatory testing - Ethics on how health budgets are split (Marije Versteeg-Mojanaga) - Q&A Lucy Allais Satellite Session 7 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 3 P a g e

GlaxoSmithKline session 13h30 15h00 15h00 15h30 15h30 17h00 Session 8A Cancer treatment models - Kaposi Sarcoma (Zainab Mohamed) - Lymphoma - Role of pap smears in the HIV world - Update on cancer treatment (Adam Nosworthy) Moosa Patel Refreshments, exhibition and posters Hall 5 Session 9A An update on - Integrase inhibitors (Francois Venter) - Protease Inhibitors (Sipho Dlamini) - NRTIs (Yunus Moosa) - NNRTIs (Michelle Moorhouse) - Drug-drug interaction (Gary Maartens) Session 8B Resistance - Viral resistance first-line and second-line (Graeme Meintjes) - At which detectable viral load should we switch? (Lucas Hermans) - Third-line treatment. Feedback on outcome of patients on national third-line regimen (Michelle Moorhouse) - Transmitted drug resistance: surveillance, implications, future (Cloete van Vuuren) Theresa Rossouw Session 9B What s coming / What s missing in paediatrics - Integrase inhibitors (James Nuttall) - Protease Inhibitors (Leon Levin) - Drug interactions (Mohendren Archary) Session 8C Prevention - Non-biomedical approaches (Sue Goldstein) - Condoms (Mags Beksinska) - Update on trials of vaccines and monoclonals in SA; how PrEP could augment these approaches (Fatima Laher) - Voluntary medical male circumcision (Limakatso Lebina) - Treatment as prevention (Francois Venter) Session 9C Modelling and scale-up - What are the numbers telling us - How the epidemic informs resource planning Cost effectiveness of TLD versus TEE 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 4 P a g e

17h10 18h40 18h50 20h20 Karen Cohen Session 10A Session 10B Skills building session Skills building session Resistance Counselling - Third-line (Leon Levin) - How to deliver HIV risk - Paediatric third-line reduction counselling in 2018 (Moherndran Archary) (Janan Dietrich) - Stanford database - how to - Integrating HIV prevention with interpret resistance test other services (Natasha Davies) results (Robert Shafer) Pierre Brouard Cloete van Vuuren Session 11: Debate (Open Session) Hall 4 Implications of scarcer resources for 90:90:90 (Gloria Maimela) - Panel: Elliot Raizes, Annemarie Wensing, Yunus Moosa, Jean Nachega, Francois Venter FRIDAY, 26 OCTOBER 2018 07h30 08h15 Southern African HIV Clinicians Society AGM 08h30 10h00 10h00 10h30 Session 12: Plenary Our current understanding of antibodies (Nono Mhkize) Why do we need cure (John Mellors) How do you measure cure (Monique Nijhuis) Management of patients with advanced HIV (Graeme Meintjes) Moeketsi Mathe Refreshments, exhibition and posters Session 10C Skills building session - Basic science (Carole Wallis, Gillian Hunt, Tendesayi Kufa-Chakezha) Gillian Hunt 10h30 12h00 Session 13A Session 13B Session 13C 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 5 P a g e

12h00 13h30 Opportunistic infections - An approach to intracranial mass lesions in HIV patients - Pneumocystis pneumonia - Endemic mycoses in HIV patients (Jade Mogambery) - An approach to chronic diarrhoea (Sipho Dlamini) Colin Menezes Lunch, exhibition and posters HIV and TB in children and adults - Paediatric TB diagnosis and management (Ashendri Pillay) - TB in children and HIV-TB coinfection - TB in adults and HIV-TB coinfection (Ndiviwe Mphothulo) - TB and HIV co-infection including IRIS Key populations and mobile populations - Injecting drug users in the region (Andrew Scheibe) - Sex workers including satellite clinics; peer support (Naomi Hill) - Engaging in care (Naomi Hill) - Testing in taxi ranks (Thandeka Khosa) Satellite Session 14 GILEAD session 13h30 15h00 15h00 15h30 15h30 17h00 Session 15: Plenary Botswana Dolutegravir experience (Ava Avalos) Could good point-of-care testing revolutionise issues in the region? (Peter Manyike) Balancing politicians, ministries of health, communities and donors Refreshments, exhibition and posters Session 16A Session 16B Session 16C Skills building Clinical skills building (Henry Sunpath, Yunus Moosa) TB - Should the private sector be treating TB? Yes No Kogie Naidoo Update on PMTCT - Where are we with PMTCT, including epidemiology (Landon Myer) - Transmission of HIV in breastfeeding (Ameena Goga) - Pregnant women on ART programmatic issues (Coceka Mnyani) 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 6 P a g e

17h10 18h40 Session 17A Hall 4 DTG in pregnancy and breastfeeding - Contraception, clinical issues, MPTs and new technologies (Helen Rees) Tshidi Sebitloane 19h00 22h30 Celebratory Dinner (RSVP only additional fee applies) SATURDAY, 27 OCTOBER 2018 07h30 08h15 Session 18A Meet the Professor / Clinician How did I start my academic / research career? (Dave Spencer; Francois Venter; Francesca Conradie; Yunus Moosa; Gary Maartens) Moeketsi Mathe 08h30 10h00 Session 19: Plenary Vaccinations - Overview (Benjamin Kagina) - Influenza vaccines (Shabir Madhi) - HIV vaccines - SAHCS vaccination guidelines (Sipho Dlamini) Rudzani Muloiwa 10h00 10h30 Refreshments, exhibition and posters 10h30 12h00 Session 20A Session 20B Noncommunicable diseases - Inflammation (Dave Spencer) - Hypertension Session 18B Adolescent health c/o Wits RHI Ethics and technology - Electronic medical records (Sandile Mhlongo) Session 20C Sexually transmitted infections - Strategies to achieve STI control in South Africa (Remco Peters) 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 7 P a g e

12h00 13h30 - Obesity (Denasha Reddy) - Mental health - Injection drug use, HIV and hepatitis (Moeketsi Mathe) Lunch, exhibition and posters - Digital database and the PoPI act (Siraaj Adams) - Ethico-legal framework for biobank research in SA (Safia Mahomed) Funeka Bango - Hepatitis C (Andrew Scheibe) - Update on vaginal microbiome and HIV (Jo-Ann Passmore) - In context of PrEP (Sinead Delany- Moretlwe) - Management of STIs in HIV+ population case-based (Ranmini Kuluratne) Helen Rees Satellite Session 21 Johnson & Johnson session 13h30 15h00 15h10 16h40 16h50 18h15 Session 22A Advanced HIV Management - Care of aging patients - Cryptococcal meningitis (Charlotte Sriruttan) - Palliative care (Dave Spencer) Dave Spencer Session 23A Skills building Guidelines: all new (Sipho Dlamini, James Nuttall, Natasha Davies, Michelle Moorhouse) Moeketsi Mathe Session 24: Closing Plenary Big challenges in public health Session 22B Treatment optimisation - (Polly Clayden, Francois Venter, Gary Maartens, Michelle Moorhouse, Graeme Meintjes, Landon Myer) Polly Clayden Session 23B Adherence - Adherence (Catherine Orrell) - Adherence clubs - Role of viral load testing in adherence Maria Sibanyoni Session 22C Best abstracts session Moeketsi Mathe Session 23C Quality Improvement c/o the Aurum Institute 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 8 P a g e

18h15 18h20 Big challenges in TB preventative therapy Big challenges in introducing and scaling up new prevention technologies (Helen Rees) Gary Maartens Conference closing Moeketsi Mathe 2018.07.05 Southern African HIV Clinicians Society Conference 2018 programme subject to change 9 P a g e