Accession # 07-112125 5 ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX 389662, Tukwila, WA 98138-0662 Tel: (425) 251-0596 CLIA License # 50D0630141 s For: DENISE FAZ Age: 45 Sex:Female Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Dx Code:Not Provided BAKERSFIELD CA 93313 USA Tel: 661-834-2446 Fax: 1-661-322-9313 Patient's Tel: 661-706-8012 Specimen Collected:12/22/2007 Test Description Ref Values ASI TAP * Adrenal Stress Index Free Cortisol Rhythm 01:00-03:00 AM 4 Normal 4-19 nm 07:00-09:00 AM 9 Depressed 13-24 nm 11:00-01:00 PM 6 Normal 5-10 nm 03:00-05:00 PM 1* Depressed 3-8 nm 07:00-09:00 PM 1 Depressed 3-7 nm Cortisol Burden: 21 28-68 The cortisol burden reflects the area under the cortisol curve. This is an indicator of overall cortisol exposure, where high values favor a catabolic state, and low values are sign of adrenal deterioration. Further investigation is warranted Figure 2. The Cortisol release inducers fall into 4 broad categories shown in the adjacent flowchart. Long term adrenal axis maintenance and restoration, require optimization of all the cortisol inducers. Remarks: Depressed morning cortisol, < 13 nm, is suggestive of marginal HPA (Hypothalamic-Pituitary-Adrenal) performance. Normal rhythms exhibit highest cortisol value for the day at 7-8 AM. 30 25 20 15 10 5 0 Figure 1. Circadian Cortisol Profile 1-3 AM 8 AM Noon 4 PM 7 PM Reference Ranges Patient s Figure 2. 1 Copyright DTI 1989-2008
Accession: 07-112125 Test Description Ref Values DHEA Dehydroepiandrosterone 1 Depressed DHEA Adults (M/F): 3-10 ng/ml 30 25 Figure 3. Cortisol-DHEA Correlation 3 2 1 Figure 3 shows your cortisol-dhea correlation was in: Zone 4 - Maladapted phase II This zone represents a marginal cortisol output with reduced DHEA levels reflecting a minimal adrenal reserve. The production of the precursor pregnenolone is usually limited and the adrenal cortex may show hypertrophic changes. Under stress most patients in maladaptation phase II will have a suboptimal response to stress. This suboptimal response is any response not consistent with a normal diurnal cortisol production pattern. This condition is usually the outcome of chronic and protracted stress exposure. 20 15 10 5 4 Reference 6 7 5 0 2 4 6 8 10 12 14 16 18 20 DHEA CORTISOL-DHEA CORRELATION ZONES 1. Adapted to stress. 2. Adapted with DHEA slump. 3. Maladapted Phase I. 4. Maladapted Phase II. 5. Non-adapted, Low Reserves 6. High DHEA. 7. Adrenal Fatigue. ISN Insulin Fasting 6 Normal Normal: 3-12 uiu/ml Figure 4b. Serum Insulin - Time Curve Shaded area is optimal period of post-prandial collection. 2 Copyright DTI 1989-2008
Accession: 07-112125 Test Description Ref Values P17-OH 17-OH Progesterone 34 Normal Adults Optimal: 22-100 pg/ml Borderline: 101-130 pg/ml Elevated: >130 pg/ml Figure 5. Adrenal Steroid Synthesis Pathway Figure 5. MB2S Total Salivary SIgA 10 Depressed Normal: 25-60 mg/dl Borderline: 20-25 mg/dl A depressed mucosal SIgA may be attributed to one or Basic Facts About SIgA more of the following reasons: 1. Secretory IgA (SIgA) is secreted by the various mucosal 1- Excessive chronic cortisol output causes a reduction surfaces. It is mostly a dimeric molecule. Less than 2% of Saliva is in the number of SIgA producing immunocytes. of serum origin. The secretory component of SIgA stabilizes it Appropriate restorative treatments have been shown to against enzymatic and bacterial degradation. produce incremental improvements in SIgA. 2. The main functions of SIgA include Immune Exclusion, Viral 2- Excessive sympathetic activity causes inhibition of and Toxin Neutralization, Plasmid Elimination, and Inhibition of SIgA release from the mucosal immunocytes. Bacterial Colonization. SIgA immune complexes are not 3- Chronic deficits in cortisol and/or DHEA levels. inflamatory to the mucosal surfaces. 4- Possible systemic deficit in capacity to produce IgA - an inherited problem. Rule out possibility with a serum 3. Production of SIgA is adversely affected by stress which is IgA test. A normal finding rules out this possibility. mediated by increased cortisol and/or catecholamine levels. FI4 Gliadin Ab, SIgA 4 Negative Borderline: 13-15 U/ml Positive: >15 U/ml Notes on Gliadin Ab Test Gliadins are polypeptides found in wheat, rye, oat, barley, and other grain glutens, and are toxic to the intestinal mucosa in susceptible individuals. Healthy adults and children may have a positive antigliadin test because of subclinical gliadin intolerance. Some of their symptoms include mild enteritis, occasional loose stools, fat intolerance, marginal vitamin and mineral status, fatigue, or accelerated osteoporosis. Scan. J. Gastroenterol. 29:248(1994). 3 Copyright DTI 1989-2008
Accession: 07-112125 Test Description Ref Values 4 Copyright DTI 1989-2008
Accession # 07-112125 5 ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX 389662, Tukwila, WA 98138-0662 Tel: (425) 251-0596 CLIA License # 50D0630141 s For: DENISE FAZ Age: 45 page: 1 Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Gender:Female PHP1. BAKERSFIELD CA 93313 USA Tel: 661-834-2446 Fax: 1-661-322-9313 Postmenopausal Hormone panel -- Short Patient's Tel: 661-706-8012 Specimen Collected: 12/22/2007 Copyright DTI 1994-2008 Hormone Notes Reference Ranges TTF - Testosterone 9 Normal Borderline: 5-7 pg/ml Normal: 8-20 pg/ml E1 - Estrone 14 Normal for Age 40-49: 38-68 pg/ml E2 - Estradiol 11 Postmenopause-No HRT: 1-4 pg/ml HRT Target Range: 5-13 pg/ml Follicular: 5-13 pg/ml Luteal: 7-20 pg/ml E3 - Estriol 13 Postmenopause-No HRT: 7-18 pg/ml HRT Target Range: 14-38 pg/ml Cycling Female: 12-25 pg/ml P1 - Progesterone >1000 Postmenopause-No HRT: 5-95 pg/ml HRT Target Range: 100-300 pg/ml Follicular: 20-100 pg/ml Luteal: 65-500 pg/ml More interpretation and the action plan on following pages. Diagnosis Code: Not Provided To The Lab. Please Note: All examples of patient treatment or therapy are for illustrative and/or educational purpose. Use this report in context of the clinical picture before initiating hormone or other therapies.
Accession: 07-112125 Breast Proliferation Index (BPI) TM 40 6 5 3 35 TM Uterine Proliferation Index (UPI) 400 6 5 1 350 page: 2 30 25 20 15 10 5 0 7 8 4 Optimal ZONE 5 10 15 20 25 30 35 40 1. Enhanced Proliferation. 2. High Proliferative Potential. 3. Hormone Overload. 4. Pro-Proliferative. 2 1 PrA (EA + P1 Activity) 5. Mild Androgen Dominance. 6. Frank Androgen Excess. 7. Female Hormone Deficit. 8. Hypogonadism with Atrophy. Legend Patient PrA - Proliferative Activity EA - Estrogenic Activity 300 250 200 150 100 50 0 7 8 3 Optimal ZONE 5 10 15 20 25 1. Enhanced Proliferation. 2. High Proliferative Potential. 3. Potentially Proliferative. 4. Accentuated Hormone Imbalance. 4 2 EA (E2 Equivalents) 30 5. Mild Imbalance. 6. Pre-Atrophic. 7. Pro-Atrophic. 8. Atrophic. Copyright DTI 1994-2008
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Accession # 07-112125 5 ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX 389662, Tukwila, WA 98138-0662 Tel: (425) 251-0596 CLIA License # 50D0630141 Subject: DENISE FAZ Age: 45 Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Gender:Female BAKERSFIELD CA 93313 USA Tel: 661-834-2446 Fax: 1-661-322-9313 Patient's Tel: 661-706-8012 Specimen Collected: 12/22/2007 Code Test Name Values Provisional Ranges STP Saliva Thyroid Study ftsh Thyroid stimulating hormone 41 Normal Borderline Low: 20-25 niu/ml Normal: 26-85 niu/ml Borderline High: 86-120 niu/ml ft4 L-Thyroxine 0.19 Normal Normal: 0.17-0.42 ng/dl ft3 Triiodo-thyronine 0.32 Normal Borderline Low: 0.21-0.27 pg/ml Normal: 0.28-1.10 pg/ml TPO Thyroid Microsomal Ab, SIgA Negative Normal: Negative The Saliva Thyroid tests are intended for research use only and not as stand alone diagnostic tests. Additional tests may be required. s should be contextualized into the over all clinical picture. These values reflect unbound "Tissue-Delivery" concentrations which may not neccessarily correlate with serum hormone levels. 1 Copyright DTI 1999-2008
Accession # 07-112125 5 ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX 389662, Tukwila, WA 98138-0662 Tel: (425) 251-0596 CLIA License # 50D0630141 s For: DENISE FAZ Age: 45 Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Gender:Female BAKERSFIELD CA 93313 USA Tel: 661-834-2446 Fax: 1-661-322-9313 Patient's Tel: 661-706-8012 Specimen Collected: 12/22/2007 Code Test Name / Notes Reference Values/Key CS3 Diagnosis Code: Fungal Cu. Isol. & I.D. Not Provided To The Lab. Source not specified: Swab culture +1 trace amount of Candida albicans isolated. +1=Trace +2=Light +3=Moderate +4=Abundant +5=Confluent Please Note: All examples of patient treatment or therapy are for illustrative and/or educational purpose. Use this report in context of the clinical picture before initiating hormone or other therapies. 1 Copyright DTI 1999-2008