ADVANCED CLINICAL CANNABINOID PROVIDER EXAM ACCP Page 1 1. In what year did the possession and transfer of cannabis for recreational use become illegal in the United States? A. 1937 B. 1941 C. 1933 2. In what year were cannabis and cannabis-based products removed from the US Pharmacopeia A. 1943 B. 1944 C. 1937 3. Cannabis is an herb which is a member of what family? A. Marijuana B. Hemp C. Cannabinoid 5. Which plant(s) are cultivated for medical use? A. Hybrids B. Male C. Female 6. Where are trichomes clustered? A. On the stems B. On female flowers C. On the receptors 7. The oil oozed by trichomes is called A. Cannabinoid Oil B. Terpenes C. THC 8. THC and CBD come from what part of the plant? A. Terpenes B. Flowers C. Trichomes 9. Female cannabis plants produce: A. Seed B. Pollen C. Hemp 10. What are the three major strains of cannabis? A. Indica, Sativa, THC B. THC, CBD, Sativa
C. Indica, Sativa, Hybrid* Page 2 11. The best strain to prescribe for seizures is: A. CBD B. Sativa C. Indica 12. The best strain to prescribe for depression is A. Sativa B. Indica C. CBD 13. The best strain to prescribe for pain is A. THC B. Indica C. Sativa 13. The most common delivery method is: A. Inhalation B. Ingestion C. Ointment 15. One key advantage to vaporization over smoking is A. Indigestion B. Avoiding toxins released during combustion C. Slower release into system 16. During vaporization, beneficial ingredients are extracted? A. THC and CBD B. CBD and Terpenes C. THC and Sativa 17. Which delivery method provides the most specific dosage control? A. Free-basing B. Edibles C. Tinctures and liquids 18. Which delivery method takes longest to take effect? A. Edibles B. Ointments C. Inhalation 19. Two types of inhalation include: A. Snorting and Vaporizing
B. Snorting and Smoking C. Smoking and Vaporizing Page 3 20. Potential pain management by cannabinoid treatments relies on A. Cb1 AND Cb2 receptors B. Deep inhalation of vapors C. Delivery method 21. CB1 receptors are concentrated in the A. Brain B. Spinal Cord C. Nervous system 22. CB2 receptors are focused in areas controlling A. Immune functions B. Bowel Movements C. Depth perception 23. Because the brain stem lacks cannabinoid receptors, there is no danger of A. Decreased metabolism B. Respiratory distress C. Ocular pressure 24. Most studies on the use of cannabis are based on which delivery method? A. Truck B. Injection C. Smoking 25. Improper usage of cannabis can result in A. Dry Mouth B. Nausea C. Both 26. The endocannabinoid system is: A. A chemical system in the brain responsible for homeostasis B. A system of receptors in the body responsible for breathing C. A system of nerves in the body responsible for breathing, digestion and homeostasis 27. Manipulation of ECS through introduction of cannabinoids may determine the body s: A. Breathing rate B. Distance perception B. Disease response 28. The endocannabinoid system is the key between: A. Body and mind
B. Spinal cord and limbs C. Nervous system and limbs Page 4 29. The endocannabinoid system is a signaling system composed of: A. CB1 and cannabinoids B. CB1 and CB2 receptors C. CB2 and tissue level enzymes 30. The body produces cannabinoids such as: A. Tetrahydrocannabinol B. THC C. Anandamide and 2-arachidonoylglycerol 31. Cannabidiol is also known as A. CBD B. CBN C. CB1 and CB2 32. Cannabidiol produces: A. Direct, psychoactive effects B. Indirect, psychoactive effects C. Indirect, non-psychoactive effects 33. Cannabinol is also known as A. CBD B. CB2 C. CBN 34. Cannabinol is the key to: A. CB1 receptors B. CB2 receptors C. CB1 and CB2 receptors 35. CB2 receptors are predominantly located in the: A. Peripheral organs and immune system cells B. Brain Stem C. Spinal column 36. CBN is: A. Extremely psychoactive B. Non-psychoactive C. Mildly psychoactive 37. Three cannabis-based drugs used in clinical practice are: A. Dronabinol, Marinol and Sativinol B. Sativinol, Marinol and Nabilone C. Dronabinol, Nabilone and Sativex
Page 5 38. An important chemical characteristic of the cannabinoid molecule s carboxylic group is: A. Increase upon drying or heating B. Decrease upon drying or heating C. Elimination upon drying or heatin 39. Which chemotype is known for having very low CBDA/THC ratio: A. Chemotype I B. Chemotype III C. Chemotype IV 40. Which chemotype is known for very high CBDA/THCA ratio: A. Chemotype I B. Chemotype III C. Chemotype II 41. Which chemotype contains approximately equal amounts of CBDA and THCA: A. Chemotype II B. Chemotype I C. Chemotype V 42. CB1 receptors include subtypes: A. CB1A and CB1B B. CBA and CBB C. CB1A1 and CB1A2 43. CB1 receptors are localized in the: A. Brain Stem B. Spinal Column C. Nervous System 44. CB1 receptors are: A. Not located in some organs and peripheral tissues B. Located in some organs and peripheral tissues to a lesser extent C. Located only in the brain 45. CB1 receptors: A. Reduce neuronal cell activity B. Increase neuronal cell activity C. Have no impact on neuronal cell activity 46. CB1 receptors: A. Have no impact on serotonin B. Interfere with release of serotonin
C. Increase levels of serotonin and GABA Page 6 47. CB1 receptors: A. Interfere with release of histamine B. Increase levels of histamine C. Have no impact on histamine 48. CB2 receptors are: A. Not located in the brain B. Predominately located in the brain C. In the brain in in low amounts 49. CB2 receptors may be found in the brain in: A. Procaryote B. Mycroglial cells C. Eukaryote 50. CB2 receptors have potent anti-inflammatory effects, releasing: A. Terpenes B. Histamines C. Cytokines