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CAMBRIDGE INTERNATIONAL EXAMINATIONS Cambridge Ordinary Level MARK SCHEME for the October/November 2015 series 5090 BIOLOGY 5090/21 Paper 2 (Theory), maximum raw mark 80 This mark scheme is published as an aid to teachers and candidates, to indicate the requirements of the examination. It shows the basis on which Examiners were instructed to award marks. It does not indicate the details of the discussions that took place at an Examiners meeting before marking began, which would have considered the acceptability of alternative answers. Mark schemes should be read in conjunction with the question paper and the Principal Examiner Report for Teachers. Cambridge will not enter into discussions about these mark schemes. Cambridge is publishing the mark schemes for the October/November 2015 series for most Cambridge IGCSE, Cambridge International A and AS Level components and some Cambridge O Level components. IGCSE is the registered trademark of Cambridge International Examinations.

Mark schemes will use these abbreviations: Page 2 Mark Scheme Syllabus Paper ; separates marking points / alternatives () contents of brackets are not required but should be implied R reject A accept (for answers correctly cued by the question, or guidance for examiners) I ignore (for incorrect but irrelevant responses) AW alternative wording (where responses vary more than usual) AVP alternative valid point (where a greater than usual variety of responses is expected) ORA or reverse argument underline actual word underlined must be used by candidate (grammatical variants excepted) max indicates the maximum number of marks that can be given + statements on both sides of the + are needed for that mark

Page 3 Mark Scheme Syllabus Paper 1 (a) (cell) membrane / cytoplasm / nucleus ; pulled / moved away from (cell) wall / plasmolysed ; vacuole ; reduced in size / smaller / AW ; [max. 3] (b) ref. direction of water potential / concentration gradient / AW ; osmosis / diffusion ; (movement of) water out of cells ; ref. partial permeability AW of (cell) membrane ; [max. 3] [Total: 6]

Page 4 Mark Scheme Syllabus Paper 2 (a) X right ventricle ; pulmonary artery ; Y left ventricle ; aorta ; [4] (b) (i) line decreases (lowest at capillaries) followed by increase ; vein diameter drawn to be higher than artery ; [2] (ii) ref. heart / ventricle + pump / source of pressure ; pressure relates to distance from heart / pump ; resistance / friction ; narrow lumen (in artery) ; A arteries take blood from / are close to heart ORA for vein thick / muscular / elastic walls (in artery) ; generation of tissue fluid in capillaries ; [max. 4] (c) (i) valve ; prevents backflow of blood / allows flow in one direction only ; [2]

Page 5 Mark Scheme Syllabus Paper (ii) muscle(s) ; contract ; put pressure + wall of vein / blood in vein ; [max. 2] [Total: 14]

Page 6 Mark Scheme Syllabus Paper 3 (a) (i) discontinuous ; [1] (ii) no intermediate values / distinct / separate categories ; [1] (iii) (63 / 100) 10 ; 6.3 million / 6 300 000 / 6.3 10 6 ; [2] award 2 marks for correct answer alone (b) (i) 4 (%) ; [1] (ii) ref. alleles / genes ; each person has two (for blood group) ; different (allele / gene) frequency in different populations ; ref. inbreeding (of separate groups) AW ; [max. 2] A example of inbreeding e.g. geographical isolation / culture (c) blood transfusion / tissue (A blood donor) / organ transplant ; clotting with ref. to blood / prevent rejection ; A if ref. is to donor or recipient A ORA to check paternity ; [max. 2] (d) I A I o + I B I o ; A + B ; [2] [Total: 11]

Page 7 Mark Scheme Syllabus Paper 4 (a) (i) 11 / 12 day(s) ; A 11 th or 12 th day 13 / 14 day(s) ; [2] (ii) day 14 ; [1] (iii) progesterone (concentration) falls / not maintained ; ref. figure day 24 28 ; progesterone needed to maintain lining / pregnancy ; [max. 2] (b) FSH ; development of follicle / maturation / release of egg / ovum ; stimulates production of oestrogen ; oestrogen ; repairs / builds up / thickens / develops uterus lining ; maturation of egg / ovum ; inhibits production of FSH ; stimulates production of LH ; LH ; ovulation / release of egg / ovum ; [1] [max. 1] [1] [max. 1] [1] [1] [max. 4] [Total: 9] A oestradiol for oestrogen throughout

Page 8 Mark Scheme Syllabus Paper 5 (a) wilting: root hairs removed / roots damaged ; stem / xylem damaged ; less water absorbed ; R no water absorbed plant loses water / transpires ; cells lose water / cells become flaccid ; recovery: root (hairs) regrow ; allow max.3 marks for wilting answers (more) water absorbed ; cells gain water again / become turgid ; [max. 4] (b) carbon dioxide + water oxygen ; [1] accept words or chemical formulae or a correctly balanced symbol equation I light / chlorophyll (c) (i) P = (lower) epidermal cell / epidermis / epidermal layer ; Q = guard cell ; R = stoma / stomata ; [3] (ii) fewer / no stomata / guard cells ; reduce / stop water loss / transpiration ; (appears) shiny / bright / ref. to cuticle ; [max. 2] [Total: 10]

Page 9 Mark Scheme Syllabus Paper 6 (a) molecules large + must be converted to smaller ; insoluble + need to be converted to soluble / non-diffusible to diffusible AW ; to be absorbed ; from (small) intestine / ileum ; A across intestine wall / into villi into blood / capillaries / lymph / lacteals ; [max. 3] (b) bile from + liver / gall bladder / bile duct ; ref. emulsification ; increased surface area ; ref. provision of optimum ph / alkaline conditions ; small intestine / duodenum ; lipase ; from pancreas ; fatty acids ; glycerol ; [max. 7] [Total: 10]

Page 10 Mark Scheme Syllabus Paper 7 (a) ciliary muscles ; relax ; suspensory ligaments ; tighten / become taut / pulled AW ; increased tension / pull on lens ; lens long + thin / flatter / less fat / convex ; light refracted / bent (by lens) ; R bent more (light) converges / (produces image) on retina / fovea ; [max. 6] (b) nervous system quicker AW / hormones slower ; example of relevant situation ; electrical / impulses ; via neurones / nerve cells ; hormones are chemical ; carried / transported via blood ; [max. 4] [Total: 10]

Page 11 Mark Scheme Syllabus Paper 8 1 red blood cells + transport / absorb / carry oxygen AW ; 2 no nucleus / biconcave / doughnut shape AW + increased surface area ; A any three components named for 1 mark max. if no marks awarded for lack of accompanying explanations 3 (oxy)haemoglobin ; 4 ref. (oxygen) diffusion into tissues / red blood cells ; 5 white blood cells / named + immunity / immune system / destroy pathogens / bacteria / viruses / named pathogen ; I germs / foreign bodies 6 phagocytes / phagocytosis ; 7 antibodies / anti-toxins ; 8 ref. tissue rejection ; 9 plasma + transport / carry ; 10 dissolved / in solution ; 11 two named chemicals transported ; A urea, CO 2, vitamins, etc. 12 heat transported ; 13 platelets + blood clotting / plug hole ; 14 fibrinogen + to fibrin ; [max 10] [Total: 10]

Page 12 Mark Scheme Syllabus Paper 9 (a) removal from organism / body ; toxic / poisonous ; waste (products) ; from metabolism ; [max. 3] (b) 1 blood from patient to machine / returned to patient ; 2 using partially permeable membrane / tubes AW ; 3 ref. dialysis fluid ; 4 ref. relative concentrations AW ; 5 filters / removes substances from + blood / unwanted out / wanted in ; 6 by diffusion ; 7 urea / nitrogenous products / toxins / poisons ; 8 salt(s) / ions / small molecules ; 9 excess water / ref. osmoregulation ; 10 large molecules / proteins stay in blood ; 11 practical aspect e.g. bubble trap / repetition / frequency / duration of procedure / dialysis fluid frequently changed / temperature ref / counter flow ; [max. 7] [Total: 10]