FOCIS goes South: ADVANCES IN TRANSLATIONAL AND CLINICAL IMMUNOLOGY

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FOCIS Center of Excellence Millennium Institute on Immunology and Immunotherapy & The Federation of Clinical Immunology Societies, FOCIS WORKSHOP FOCIS goes South: ADVANCES IN TRANSLATIONAL AND CLINICAL IMMUNOLOGY May 15 th -17 th 2017, Santiago de Chile 1

MEETING PROGRAM May 15 th 9h00-17h30. Coffee break at 10h30, Lunch from 13h00-13h45h and Coffee break at 15h15. Advances and Future Prospects in Immunology. Dr. Abul Abbas, University of California San Francisco, USA. 9h00 9h30 10h30 11h00 12h00 13h00 13h45 14h30 15h15 15h45 16h45 Introduction to the Immune System Innate Immunity Break Antigen Presentation, T Cell Activation and Costimulation CD4 T Cell Subsets, Cytokines Lunch B Cells and Antibodies T Cell Regulation and Tolerance I. Central and Peripheral Tolerance Break T Cell Regulation and Tolerance II. Regulatory T Cells, Failure of Tolerance Tumor Immunity 17h30. Adjourn May 16 th 8h00-8h40. 8h40-8h50. 8h50-9h00. Session 1. Registration Welcome words and Presentation of the FOCIS Center of Excellence Millennium Institute on Immunology and Immunotherapy. Dr. Alexis. Kalergis, Director of the FCE Millennium Institute on Immunology and Immunotherapy. Welcome words and Presentation of the Federation of Clinical Immunology Societies (FOCIS). Dr. Abul Abbas, Member of the board of FOCIS. 2

9h00-9h30. The Treg IL-2R as a target for immunotherapy. Dr. C. Garrison Fathman, Stanford University FCE, School of Medicine, USA. 9h30-10h00. The intestinal lamina propria is a unique niche for regulatory T cells. Dr. Terri Laufer, University of Pennsylvania FCE, USA. 10h00-10h30. Mapping of the functional dynamics of regulatory T cells. Dr. Ciro Piccirillo, Montreal Diabetes Research Center, Montreal General Hospital, McGill, Montreal University, Canada. 10h30-11h00. Coffee break, poster and exhibitors viewing. Session 2. 11h00-11h30. Establishing determinants of human immune variability as a path towards personalized medical approaches. Dr. Milena Hasan. Pasteur Institute FCE, Paris, France. 11h30-12h00. Phase 2 and 3 clinical trials of a single dose virus attenuated tetravalent dengue vaccine. Dr. Jorge Kalil, University of São Paulo FCE, Brazil. 12h00-12h30 Unforeseen functions for CD43 (sialophorin). Dr. Yvonne Rosenstein, Departamento de Medicina Molecular y Bioprocesos, Universidad Autónoma de México, Cuernavaca, México. 12h30-12h40. New and old drugs to control inflammation, Centre for Translational Immunology. Dr. Marcelo Hill, Instituto Pasteur de Montevideo, Montevideo, Uruguay 12h40-13h40. Lunch, poster and exhibitors viewing. Session 3. 13h40-14h10. Tolerogenic dendritic cell therapy in humans: application to kidney transplantation. Dr. Maria Cristina Cuturi, Nantes University and INSERM FCE. 14h10-14h20. Mucosal inflamamtion in the gut. Dr. Guillermo Docena, Universidad de la Plata, La Plata, Argentina. 3

14h20-14h30 1 oral presentation (10 min) from abstracts. 14h30-15h00. CD8 + Tregs in rodent and human models of organ transplantation and GVHD. Dr. Ignacio Anegon, Nantes University and INSERM FCE. 15h00-15h30. Coffee break, poster and exhibitors viewing Session 4. 15h30-16h00. Melanoma Cancer and Immunotherapy Dr. Flavio Salazar, FCE Millennium Insititute on Immunology and Immunotherapy, Universidad de Chile. 16h00-16h30. 3 oral presentations (10 min each) from abstracts. 16h30 17h00. Using SLE risk alleles to understand pathogenesis. Dr. Betty Diamond, The Feinstein Institute for Medical Research FCE, Northwell Health, USA. 17h00-17h15. Closing words: Dr. Alexis Kalergis, Director of the Millennium Institute on Immunology and Immunotherapy. 17h15-17h45. Coffee break, poster and exhibitors viewing. 17h45-19h00. Short walk around the premises and visit to the nearby Cerro Santa Lucía. May 17 th 9h30-17h00. Coffee break at 11h, Lunch from 12h30-14h and Coffee break at 15h30. Flow Cytometry Course 4

Local Organizing Committee: Organizers: Dr. Alexis Kalergis, Director of the FCE Millennium Institute on Immunology and Immunotherapy; Full Professor, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile. Dr. Ignacio Anegon, Director of FCE Nantes University and Multinational FCEs, INSERM 1064- CRTI. Dr. Pablo González, Associate Investigator, FCE Millennium Institute on Immunology and Immunotherapy; Assistant Professor, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile. Contact: Virna Salazar, vsalazar@bio.puc.cl Pablo González, pagonzalez@bio.puc.cl Meeting web site: www.imii.cl This workshop is supported by the Vicerrectoría de Investigación of the Pontificia Universidad Católica de Chile 5