Traumatic Brain Injury Pathway, GCS 15 Closed head injury

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Traumatic Brain Injury Pathway, GCS 15 Closed head injury Plus Any One of the Following Mild TBI 2010 Consensus Definition of TBI from CDC, NINDS, NIDDR, VA, DVBIC, DCoE Plus Any One of the Following New Orleans Criteria (NOC) for Head CT with GCS 15 1. Headache 2. Vomiting 3. Age older than 60 years 4. Drug or Alcohol Intoxication 5. Persistent Anterograde Amnesia 6. Visible trauma above the clavicle 7. Seizures YES NO Acute Finding CT Head No Acute Finding ADMISSION See Minimal TBI Pathway, and/or TBI Pathway, GCS 9-15 D/C with Head Injury Instruction packet Follow-up: If postconcussive symptoms, then Trauma NP Clinic

Minimal Traumatic Brain Injury Pathway Positive Head CT Blunt Trauma GCS = 15 without seizures at Trauma Consultation Pre-injury Anticoagulants or Antiplatelet agents? NO YES Isolated pneumocephalus With/without Non-displaced Skull Fracture Q4h Neurological checks For 24h post-injury Surgery OK 12h post-injury Speech-Cognition Consult Post-TBI Seizure/DVT Protocols Traumatic SAH present With/without Non-displaced Skull Fracture Q2h Neurological checks For 24h post-injury Surgery OK 12h post-injury Speech-Cognition Consult Post-TBI Seizure/DVT Protocols Concerns &/or Other Findings (e.g., IPH, EDH, SDH, Non-traumatic SAH, Displaced skull fracture) Neurosurgery Consultation New/Progressive CT Findings Any Decline in Neurologic Exam Unexplained GCS decline New focal neurologic sign or Seizure Abnormal pupillary exam New Delirium New Agitation STAT Head CT

Traumatic Brain Injury Pathway, GCS 9-15 Positive CT Head Failed Minimal TBI Pathway or GCS 9-15 (any mechanism) on initial evaluation ADMISSION Consult Neurosurgery Consult Speech-Pathology 7d Seizure prophylaxis protocol CBC, PT/INR, PTT Consider Repeat Imaging within 6-24h, if any of following: High Risk CT Features: 1. Subdural 2. Epidural 3. Intracerebral hemorrhage Clinical Deterioration Anticoagulant/Antiplatelet Use Consultant request

Traumatic Brain Injury Pathway, GCS < 9 ADMISSION WITH POSITIVE HEAD CT Consult Neurosurgery Consult Speech-Pathology 7d Seizure prophylaxis protocol CBC, PT/INR, PTT Intubation Keep PaCO 2 35-40, PaO 2 >60 HOB > 30 degrees or reverse Trendelenberg SBP > 90 mm Hg If ICH, SDH, EDH à FFP/Platelets for INR<2.0 / Platelet > 100K Establish central access, arterial line; Maintain euvolemia Optimize Sedation and Analgesia Low threshold for Hyperosmolar Therapy If ICP Monitor Placed Note: TICU attending may request with direct discussion with NSU attending If EVD, then drain CSF Contact TICU attending or fellow Contact Neurosurgery (decompressive craniectomy) Monitor Intra-abdominal pressures Consider pentobarbital coma with Neurology consult (Continuous EEG) Consider Palliative care consult CPP<60 1 st line: Phenylephrine 2 nd line: Norepinephrine CPP<60 Hyperosmolar Therapy 3% NaCl @ 30-50 ml/hr CVP High: Mannitol bolus q6h CVP low: 3% NaCl bolus q6h Q6h BMP, Osm Max: Na 160, Osm 320 Persistent and/or CPP < 60

Mild TBI References Haydel. Clinical decision instruments for CT scanning in minor head injury. JAMA (2005) vol. 294 (12) pp. 1551-3 Haydel. The Canadian CT Head Rule. Lancet (2001) vol. 358 (9286) pp. 1013-4 Haydel et al. Indications for computed tomography in patients with minor head injury. N Engl J Med (2000) vol. 343 (2) pp. 100-5 Jagoda. Mild traumatic brain injury: key decisions in acute management. Psychiatr Clin North Am (2010) vol. 33 (4) pp. 797-806 Joseph B, Pandit V, Haider AA, et al. Improving Hospital Quality and Costs in Nonoperative Traumatic Brain Injury: The Role of Acute Care Surgeons. JAMA Surg (2015) vol 150(9) pp. 866-72 Menon et al. Position Statement: Definition of Traumatic Brain Injury. Arch Phys Med Rehabil (2010) vol. 91 (11) pp. 1637-1640 Thurman and Guerrero. Trends in hospitalization associated with traumatic brain injury. JAMA (1999) vol. 282 (10) pp. 954-7 Severe TBI Carney N, Totten AM, O Reilly C, et al. Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery 2016;80(1):6 15. Feinstein et al. Resuscitation with pressors after traumatic brain injury. J Am Coll Surg (2005) vol. 201 (4) pp. 536-45 Marshall et al. Pentobarbital coma for refractory intra-cranial hypertension after severe traumatic brain injury: mortality predictions and one-year outcomes in 55 patients. J Trauma (2010) vol. 69 (2) pp. 275-83 Patel MB, Guillamondegui OD. Severe Traumatic Brain Injury: Medical and Surgical Management. Section: Head Injury. In: Papadakos P, Gestring M, editors. Encyclopedia of Trauma Care. Heidelberg, Berlin: Springer-Verlag; 2015. p. 1711 6. Vella M, Crandall MA, Patel MB. Acute Management of Traumatic Brain Injury. Surgical Clinics of North America. 2017; 97(5):1015-1030. PMCID: PMC5747306. Wakai et al. Mannitol for acute traumatic brain injury. Cochrane Database Syst Rev (2007) (1) pp. CD001049