Test Name Results Units Bio. Ref. Interval

Similar documents
Test Name Results Units Bio. Ref. Interval

Test Name Results Units Bio. Ref. Interval

5/6/ :35:00AM 5/6/ :57:28AM 5/6/2017 3:49:09PM A/c Status. Test Name Results Units Bio. Ref. Interval

6/3/2018 9:37:00AM 6/3/2018 9:39:05AM 6/3/2018 1:44:56PM A/c Status. Test Name Results Units Bio. Ref. Interval Bilirubin Direct 0.

* * Interpretation

* * : : : Final. (Automated Strip Test, Microscopy) Colour Specific Gravity Nil

15/9/2017 4:23:00PM 15/9/2017 4:26:06PM 20/9/2017 4:58:24PM A/c Status. Test Name Results Units Bio. Ref. Interval < >40.00 mg/dl <150.

1/9/ :00:00AM 1/9/ :39:34AM 6/9/2017 9:08:54AM A/c Status. Test Name Results Units Bio. Ref. Interval 70.00

15/9/2017 4:21:00PM 15/9/2017 4:29:07PM 19/9/2017 7:27:01PM A/c Status. Test Name Results Units Bio. Ref. Interval Bilirubin Direct 0.

M-Protien, what to do next? Ismail A Sharif MD, FRCPc Internal Medicine Day 22 nd April 2016

Test Name Results Units Bio. Ref. Interval ALLERGY, INDIVIDUAL MARKER, BANANA, SERUM (FEIA) 0.42 kua/l

Test Name Results Units Bio. Ref. Interval

15/9/2017 4:23:00PM 15/9/2017 4:26:23PM 20/9/2017 5:00:25PM A/c Status. Test Name Results Units Bio. Ref. Interval < >40.00 mg/dl <150.

Case #1. Robert J. Glinert, M.D. David C. Fisher, M.D. Dana Farber Cancer Institute

Forms Revision: Myeloma Changes

Laboratory diagnosis of plasma proteins and plasma enzymes

Hematology 101. Rachid Baz, M.D. 5/16/2014

Separation of Main Proteins in Plasma and Serum

Hematology Case Conference 8/5/03

Smoldering Multiple Myeloma. A Case Study

BIOCHEMICAL REPORT. Parameters Unit Finding Normal Value. Lipase U/L Amylase U/L

ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI CLINICAL RESEARCH CENTER ALDO E FOR CELE RARE DACCO DISEASES ALDO E CELE DACCO

Expanding Spectrum of Diseases Associated with Plasma Cell Dyscrasias

Test Name Results Units Bio. Ref. Interval. Positive

Slide 1: Perioperative Management of Anticoagulation

SWOG ONCOLOGY RESEARCH PROFESSIONAL (ORP) MANUAL RESPONSE ASSESSMENT MYELOMA CHAPTER 11C REVISED: SEPTEMBER 2016

Southern Derbyshire Shared Care Pathology Guidelines. MGUS (Monoclonal Gammopathy of Undetermined Significance)

Monitoring Hepatitis C

Recommendations for Celiac Disease Testing. IgA & ttg IgA

, Malcolm Tait, Barry Frank Jacobson, Evashin Pillay and Susan J. Louw. Elizabeth Sarah Mayne *

Importancia del laboratorio en el seguimiento clínico de pacientes con mieloma múltiple

Chapter 1 Introduction

Tracking Disease Status for Multiple Myeloma

Hamilton Regional Laboratory Medicine Program

2016: Plasma Cell Disorders Pre-HCT Data

Jo Abraham MD Division of Nephrology University of Utah

Serum free light chain (SFLC) assays. Dr Sarah Sasson SydPath Registrar

I have no disclosures relevant to this presentation LIVER TESTS: WHAT IS INCLUDED? LIVER TESTS: HOW TO UTILIZE THEM OBJECTIVES

Plasma Cell Disorders (PCD) Pre-HCT Data

Plasma proteins Quantitatively, proteins are the most important part of the soluble components of the blood plasma.

Interpreting Liver Function Tests

Chemistry Reference Ranges and Critical Values

Chemistry Reference Ranges and Critical Values

Laboratory Examination

Early View Article: Online published version of an accepted article before publication in the final form.

Multiple Myeloma Advances for clinical pathologists & histopathologists

The risk of venous thromboembolic disease in patients with monoclonal gammopathy of undetermined significance

NEW RCPCH REFERENCE RANGES-

Hepatocytes produce. Proteins Clotting factors Hormones. Bile Flow

Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance

Abnormal Liver Chemistries. Lauren Myers, MMsc. PA-C Oregon Health and Science University

Monoclonal Gammopathies and the Kidney. Tibor Nádasdy, MD The Ohio State University, Columbus, OH

Original Research Article

The ABCs of Waldenström s Macroglobulinemia (WM)

Elevation of Plasmin-α2-plasmin Inhibitor Complex Predicts the Diagnosis of Systemic AL Amyloidosis in Patients with Monoclonal Protein

Test Name Results Units Bio. Ref. Interval. Positive

Cancer Research Group Version Date: June 22, 2016 NCI Update Date: November 13, Schema

Hamilton Regional Laboratory Medicine Program

EXAM COVER SHEET. Course Code: CLS 432. Course Description: Clinical Biochemistry. Final Exam. Duration: 2 hour. 1st semester 1432/1433.

CASE STUDIES IN CLINICAL APPLICATIONS OF THERAPEUTIC PLASMA EXCHANGE

A Look at Patient Compliance to INR Testing and Therapeutic Range Management of Patients on Warfarin at Agassiz Medical Center.

FIBRILLARY GLOMERULONEPHRITIS DIAGNOSTIC CRITERIA, PITFALLS, AND DIFFERENTIAL DIAGNOSIS

3rd Pannonia Congress of Pathology. Slide seminar / Gastrointestinal pathology: Case Nr. 1. Lukáš Plank

Turbidos. Design Verification. Contents

TYPE 1 GAUCHER DISEASE PRESENTING AS PERSISTENT THROMBOCYTOPENIA, ASSOCIATED FACTOR XI DEFICIENCY & EMERGENT MYELOMA

Omar Alnairat. Tamer Barakat. Bahaa Abdelrahim. Dr.Nafez

DESIGN DE L ETUDE Environ 406 patients seront randomisés dans l un des 3 bras de l étude selon le schéma cidessous

Tarek ElBaz, MD. Prof. Internal Medicine Chief, Division of Renal Medicine Al Azhar University President, ESNT

Hematology Revision. By Dr.AboRashad . Mob

A Rational Evidence-based Approach to Abnormal Liver Tests

monoclonal gammopathy of undetermin Citation Rheumatology international, 33(1),

Primary Care practice clinics within the Edmonton Southside Primary Care Network.

Case Report A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features

Result Electrophoresis Tests

Challenges in Coagulation

Patterns of abnormal LFTs and their differential diagnosis

HAEMATOLOGY. Test Name Status Result Unit Reference Interval HbA1c (Glycated Haemoglobin) 5.4 % Method : HPLC Sample Type : Whole Blood EDTA

Factor II Mutation (Prothrombin Mutation)

Biochemical Investigations in Liver Disease. Dr Roshitha de Silva Department of Pathology Faculty of Medicine University of Kelaniya

Multiple Myeloma (MM)

BC Biomedical Laboratories Adult Reference Ranges

Multiple Myeloma 101: Understanding Your Labs

Wilson Disease Patient Lab Tracker

Smoldering Myeloma: Leave them alone!

Case Report Obstructive Jaundice as Initial Presentation of Multiple Myeloma: Case Presentation and Literature Review

Jonathan Katz, MD CPMC

HEPETIC SYSTEMS BIOCHEMICAL HEPATOCYTIC SYSTEM HEPATOBILIARY SYSTEM RETICULOENDOTHELIAL SYSTEM

Dr Kirsten Herbert. Dr Melita Kenealy. MBBS(Hons) FRCPA FRACP. Common Blood Tests

Chapter 13. Plasma Proteins and Enzymes. Lecturer: Dr Abeer Shnoudeh. Clinical Chemistry William Marshall

CASE 3 AN UNUSUAL CASE OF NEPHROTIC SYNDROME

EBMT2008_22_44:EBMT :26 Pagina 424 CHAPTER 27. HSCT for primary amyloidosis in adults. J. Esteve

Malcolm P. McTaggart, PhD, 1 Jindriska Lindsay, FRCPath, 2 and Edward M. Kearney, FRCPath 1 ABSTRACT

Instructions for Plasma Cell Disorders (PCD) Post-HCT Data (Form 2116 Revision 3)

REFERENCE INTERVALS. Units Canine Feline Bovine Equine Porcine Ovine

Anaemias and other Pesky Haematology Questions

PROFILES MENU. Page no. 9 Page no. 8 Page no. 7 Page no. 6 Page no. 5. Page no. 2. Page no. 4 Page no. 3

2013 AAIM Pathology Workshop

Disclosures. Overview. Have you ever. The Perioperative Management of Anticoagulants. No financial conflicts of interest to disclose

Lec-14 د.خالد نافع. Medicine. Multiple Myeloma

Transcription:

LL - LL-ROHINI (NATIONAL REFERENCE 135091536 Age 33 Years Gender Male 1/9/2017 120000AM 1/9/2017 105100AM 1/9/2017 25258M Ref By Final LIVER FIBROSIS ANEL ROTHROMBIN TIME STUDIES (hoto optical Clot Detection) Mean Normal rothrombin Time (T) 10.70 sec atient value 17.10 sec 9.57-11.80 rothrombin Ratio (R) 1.60 International Normalized Ratio (INR) 1.59 0.90-1.10 Note 1. INR is the parameter of choice in monitoring adequacy of oral anticoagulant therapy. Appropriate therapeutic range varies with the disease and treatment intensity 2. rolonged INR suggests potential bleeding disorder / bleeding complications 3. Results should be clinically correlated 4. Test conducted on Citrated plasma Recommended Therapeutic range for Oral Anticoagulant therapy INR 2.0-3.0 INR 2.5-3.5 Treatment of Venous thrombosis & ulmonary embolism rophylaxis of Venous thrombosis (High risk surgery) revention of systemic embolism in tissue heart valves, AMI, Valvular heart disease & Atrial fibrillation Bileaflet mechanical valve in aortic position Mechanical prosthetic valves Systemic recurrent emboli Comments rothrombin time measures the extrinsic coagulation pathway which consists of activated Factor VII (VIIa), Tissue factor and roteins of the common pathway (Factors X, V, II & Fibrinogen). This assay is used to control long term oral anticoagulant therapy, evaluation of liver function & to evaluate coagulation disorders specially factors involved in the extrinsic pathway like Factors V, VII, X, rothrombin & Fibrinogen. AST (SGOT), SERUM (IFCC without 5) 69 U/L <50 atientreportscsuperanel.s_general_temlate01_sc (Version 7) age 1 of 5

LL - LL-ROHINI (NATIONAL REFERENCE 135091536 Age 33 Years Gender Male 1/9/2017 120000AM 1/9/2017 105100AM 1/9/2017 25258M Ref By Final ALT (SGT), SERUM (IFCC without 5) GGT;GAMMA GLUTAMYL TRANSETIDASE, SERUM (IFCC) ALKALINE HOSHATASE (AL), SERUM (IFCC) 73 U/L <50 59 U/L <55 243 U/L 30-120 ROTEIN, TOTAL, SERUM (Spectrophotometry) Total rotein 8.20 g/dl 6.40-8.30 Albumin 4.30 g/dl 3.50-5.20 A G Ratio 1.10 0.90-2.00 atientreportscsuperanel.s_general_temlate01_sc (Version 7) age 2 of 5

LL - LL-ROHINI (NATIONAL REFERENCE 135091536 Age 33 Years Gender Male 1/9/2017 120000AM 1/9/2017 105100AM 1/9/2017 25258M Ref By Final BILIRUBIN TOTAL, DIRECT AND INDIRECT, SERUM (DD, Calculated) Bilirubin Total 0.56 mg/dl 0.30-1.20 Bilirubin Direct 0.32 mg/dl <0.20 Bilirubin Indirect 0.24 mg/dl <1.10 atientreportscsuperanel.s_general_temlate01_sc (Version 7) age 3 of 5

LL - LL-ROHINI (NATIONAL REFERENCE 135091536 Age 33 Years Gender Male 1/9/2017 120000AM 1/9/2017 105100AM 1/9/2017 25258M Ref By Final ROTEIN ELECTROHORESIS, SERUM (Capillary Electrophoresis) rotein, Total 8.20 g/dl 6.40-8.30 Albumin 4.08 g/dl 3.50-5.78 Alpha 1 globulin 0.30 g/dl 0.17-0.42 Alpha 2 globulin 0.63 g/dl 0.31-0.87 Beta globulin 1.24 g/dl 0.49-1.35 Gamma globulin 1.95 g/dl 0.62-1.57 A G Ratio 0.99 0.90-2.00 M Spike Not Seen g/dl Interpretation No "M" spike seen. olyclonal increase in gamma globulin. Consistent with Chronic infection / Inflammation. Advised Immunoglobulins IgG, IgA & IgM estimation Comment Serum rotein electrophoresis (SE) is used to identify patients with Monoclonal gammopathies like Multiple Myeloma (MM), Waldenstrom smacroglobulinemia, AL Amyloidosis as well as premalignant conditions like Monoclonal gammopathy of unkown significance (MGUS) and Smoldering Myeloma and other serum protein abnormalities like Nephrotic syndrome, Alpha 1 antitrypsin disorder and inflammatory processes associated atientreportscsuperanel.hbelectro_sc (Version 7) age 4 of 5

LL - LL-ROHINI (NATIONAL REFERENCE 135091536 Age 33 Years Gender Male 1/9/2017 120000AM 1/9/2017 105100AM 1/9/2017 25258M Ref By Final with infection, liver diseases & autoimmune disorders. Monoclonal gammopathies indicate clonal expansion of plasma cells or mature B cells. They are present in 8% of geriatric patients and require further evaluation for monitoring & prognosis. SE can be used for monitoring response to therapy, a decrease or increase of M spike by 0.5 g/dl is considered significant. If SE alone is used as initial diagnostic screen it will be able to detect approximately 88% of all MM, 66% of AL Amyloidosis and 56% of Light Chain Deposition Disease (LCDD) patients. SE has good sensitivity in detecting intact monoclonal protein but has limited sensitivity in detecting monoclonal free light chains (FLC). Diagnosis of Light chain MM, Non secretory MM, about 40% cases of AL Amyloidosis & LCDD patients require more detailed testing which includes SE along with IFE and FLC. Dr. Anil Arora MD (athology) HOD Hemat & Imm Dr Biswadip Hazarika MD (athology) Sr. Consultant athologist Dr Himangshu Mazumdar MD (Biochemistry) Consultant Biochemist Dr. Nimmi Kansal MD (Biochemistry) HOD Biochem & IA -------------------------------End of report -------------------------------- atientreportscsuperanel.hbelectro_sc (Version 7) age 5 of 5