Medicated Assisted Treatment

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Medicated Assisted Treatment Enhancing the Potential for Recovery Part I Diana Padilla Program Manager NeC-ATTC

2 Diana Padilla, RCR, CASAC-T padilla@ndri.org Diana Padilla is a program manager at NDRI-USA, Inc., and a senior staff trainer for the Northeast & Caribbean Addiction Transfer Technology Center Network (NeC ATTC). Ms. Padilla has a 20 year history of public health service which include direct service delivery predominantly to communities of color, disseminates research to practice in curricula development, conducts evaluation activities of substance abuse treatment programs and problem solving courts, engages in chronic disease research and prevention, and instructs behavioral health professionals, prevention specialists, and drug court practitioners on addiction and recovery support practices. This webinar training is provided under New York State Office of Alcoholism and Substance Abuse Services (OASAS) Education and Training Provider Certification Number 0115. Training under a New York State OASAS Provider Certification is acceptable for meeting all or part of the CASAC/CPP/CPS education and training requirements.

3 Important Information about CASAC, CPP, CPS Hours Everyone must attend both sessions - don t leave early! Participants will receive a link for an evaluation after the 2 nd session When we receive the evaluation, we will generate a certificate for 3 CASAC, CPP, CPS hours in 3-5 business days We cannot give partial hours if you only complete one session or partial sessions If some of you are sharing computers, please type everyone s name in the Q & A (instructions on next slide) & fills out an evaluation

4 Webinar Logistics: Control Panel Raise your hand Q & A Now is when you should type in the names of persons sharing a computer, later all need to fill the evaluation to receive a certificate.

5 Regional ATTCs

6 International ATTCs

7 Goals To inform on how medicated assisted treatment works (MAT), and the factors to consider when supporting and communicating its benefits to clients/patients

8 Part I - Objectives Part I The Science and Perspectives Review current statistics and regional patterns of alcohol and opioid use Identify and address misconceptions and stigma to MAT Identify ways of how substance use affects neurological processes and resulting in consequent compulsiveness of use Review the impact of negative and positive reinforcement on the reward pathway Define bi-phasic responses of alcohol consumption List behavioral indicators of use and withdrawal from alcohol and opioids

9 Part II - Objectives May 11 th Part II The Evidence Base of MAT and Recovery Pathway List barriers to MAT List goals of medicated assisted treatment and different medications available Describe how MAT addresses the physiological symptoms of alcohol and opioid use disorders Describe how MAT facilitates pathways to recovery and how to communicate MAT benefits to clients

10

Medicated Assisted Treatment (MAT) 11 Most effective treatment for Opioid and Alcohol Use Disorders, (OUD, AUD) Methadone and buprenorphine have a strong evidence base supporting their clinical effectiveness.

Myths and Misconceptions of MAT

13 Myth #1 MAT is just a substitution of one addiction for another The dosage of medication used does not get a person high, it helps reduce opioid cravings and withdrawal. NIDA, Opioid Use Disorder Affect Millions, https://www.drugabuse.gov/publications/effective-treatments-opioidaddiction/effective-treatments-opioid-addiction

14 Myth #2 Once on Methadone, you can never get off of it Relapse rates are high following cessation of heroin and/or methadone White, W., Mojer-Torres, L., ROMM, Recovery Oriented Methadone Maintenance, http://williamwhitepapers.com/pr/ books/full_texts/2010recovery_orientedmethadon emaintenance.pdf

15 Myth #3 MAT blunts the emotions (i.e., methadone mummies) Persons on MAT report increased capacity to acknowledge and express emotion White, W., Mojer-Torres, L., ROMM, Recovery Oriented Methadone Maintenance, http://williamwhitepapers.com/pr/ books/full_texts/2010recovery_orientedmethadon emaintenance.pdf

16 Myth #4 Methadone hurts your health, (i.e., rots your bones and teeth) The safety of methadone is well established in scientific studies White, W., Mojer-Torres, L., ROMM, Recovery Oriented Methadone Maintenance, http://williamwhitepapers.com/pr/ books/full_texts/2010recovery_orientedmethadon emaintenance.pdf

17 Myth #5 Methadone makes you fat Weight gain is common among MAT patients and is a product of increased food intake and overall health. White, W., Mojer-Torres, L., ROMM, Recovery Oriented Methadone Maintenance, http://williamwhitepapers.com/pr/ books/full_texts/2010recovery_orientedmethadon emaintenance.pdf

18 Myth #6 MAT is a tool of political pacification of poor communities of color Methadone makes a positive contribution to poor communities of color White, W., Mojer-Torres, L., ROMM, Recovery Oriented Methadone Maintenance, http://williamwhitepapers.com/pr/ books/full_texts/2010recovery_orientedmethadon emaintenance.pdf

19 Myth #7 MAT is addicting Prolonged use of methadone may induce physical dependence but not addiction White, W., Mojer-Torres, L., ROMM, Recovery Oriented Methadone Maintenance, http://williamwhitepapers.com/pr/ books/full_texts/2010recovery_orientedmethadon emaintenance.pdf

The Epi of Substance Use

21 Terminology When referring to alcohol or drug problems, which term do you use, Addiction or Substance Use Disorder? Does it make a difference which term you use? Why or why not? Familiarity with terminology in how substance use and other disorders are referenced is essential to appropriate documentation in screening and assessment, and potential referral to treatment. Using recovery based language is empowering for clients.

22 How is Addiction Defined? NIDA and other entities (APA, ASAM, etc.) define addiction as a chronic, relapsing brain disease characterized by compulsive drug seeking and use, despite harmful consequences. SAMHSA and NYS OASAS uses the same definition but refers to addiction as, Substance Use Disorder, which aligns with the changes of diagnostic terms in the DSM5, (Diagnostic Statistical Manual 5). NYS Office of Alcoholism and Substance Abuse Services (OASAS), https://www.oasas.ny.gov, NIDA, The Science of Drug Abuse and Addiction: The Basics, https://www.drugabuse.gov/publications/media-guide/science-drug-abuse-addictionbasics,

23 Prevalence of Substance Use The National Survey of Drug Use and Health estimates that of the 20.1 million people who needed substance use treatment, only 10.6% received treatment. Stated another way, 1 in 23 adolescents, 1 in 7 young adults, and 1 in 15 adults aged 26 or older had an SUD in the past year. Results from the 2016 National Survey on Drug Use and Health: Summary of National Findings, https://www.samhsa.gov/data/sites/default/files/nsduh-dr-ffr2-2016/nsduh-dr-ffr2-2016.htm.

DSM5 Diagnosis: Technical Support (800) 263-6317 24 Substance Use Disorders Changes from DSM4-TR: Replaced abuse & dependence Includes 11 criteria Rates severity Deleted legal Added craving

Diagnostic Criteria: Technical Support (800) 263-6317 2 or more out of 11 in the past year Impaired Control 1. Use is longer and more over a period of time 2. Unable to stop 3. Substantial time using the substance 4. Craving Social Impairment 5. Failed roles at work/school 6. Social problems 7. Decrease in activities (i.e. work, childrearing) Risky Us 8. Hazardous use 9. Use despite physical problems Pharmacological Criteria 10. Tolerance 11. Withdrawal Diagnosis is made separately for each substance 25

Severity Along a Technical Support (800) 263-6317 26 Continuum of Substance Use # of criteria severity rating 2-3 Mild 4-5 Moderate 6+ Severe Continuum of Substance Use and Abuse, Stages of Use, http://alcoholrehab.com/drug-addiction/continuum-of-substance-use-and-abuse

27 Models of Substance Use Moral model - poor morals and lifestyle, lack of will power, a choice Disease or Medical model - belief that substance use disorder is a chronic and progressive brain disease Social or Sociocultural model - cultural standards of a society and its negative effects on individual behavior can cause substance use disorder (SUD) Biological model - emphasis is on brain structure and genetic factors as causes of SUD

28 Bio-Psycho-Social-Spiritual Model Genetic predisposition Personality traits Mental illness Stress Biological Psychological Negative influences from family, peers, environment Socio-Cultural Spiritual Sense of self Accessibility of illicit substances Lack of positive experiences

29 Brain Structure Hind Brain (Stem) o Bodily Functions Mid-Brain (Limbic) o Emotions and rewards Frontal Lobe (Prefrontal Cortex) o Judgement and reason

30 Neuron Activity

31 Neurotransmission Neurotransmission (synaptic transmission) is communication between neurons accomplished by the movement of chemicals or electrical signals (neurotransmitter) across a synapse.

32 Neurotransmitters Dopamine Affects motor movement, involved in pleasure Norepinephrine Affects heart rate, blood pressure, sweating Dilates pupils and constricts blood vessels Serotonin Affects sleep and mood

33 Biology of Motivation

Substance Use Technical Support (800) 263-6317 34 Overrides the Reward Pathway

Alcohol and Opioid Use Disorders

36 Alcohol Use Disorder (AUD) Problem drinking that becomes severe is given the medical diagnosis of alcohol use disorder or AUD if symptoms meet the criteria of the DSM5. AUD is a chronic disease characterized by uncontrolled drinking and preoccupation with alcohol and diagnosed as per the Approximately 6.2 percent or 15.1 million adults in the United States ages 18 and older had AUD in 2015. National Institute on Alcohol Abuse and Alcoholism, NIAAA, Alcohol Use Disorder https://www.niaaa.nih.gov/alcohol-health/overview-alcohol-consumption/alcohol-usedisorders

Short Term Effects of Alcohol 37 Foundation for a Drug Free World, https://www.drugfreeworld.org/drugfacts/alcohol/short-term-long-termeffects.html

38 Long Term Effects of Alcohol Binge drinking and continued alcohol use in large amounts are associated with many health problems, including: Unintentional injuries such as car crash, falls, burns, drowning Intentional injuries such as firearm injuries, sexual assault, domestic violence Increased on-the-job injuries and loss of productivity Increased family problems, broken relationships Alcohol poisoning High blood pressure, stroke, and other heart-related diseases Liver disease Nerve damage Foundation for a Drug Free World, https://www.drugfreeworld.org/drugfacts/alcohol/short-term-long-termeffects.html

39 AUD Treatment Considerations Medication assisted treatment such as Acamprosate, Naltrexone or Disulfiram (Antabuse) should be used in patients with alcohol use disorder, moderate to severe subtype, who: Have current, heavy use and ongoing risk for consequences from use Are motivated to reduce alcohol intake Prefer medication along with or instead of a psychosocial intervention Do not have medical contraindications to the individual drug UpToDate, Pharmacotherapy for alcohol use disorder, https://www.uptodate.com/contents/pharmacotherapy-for-alcohol-use-disorder

40 Opioid Overdose Crisis In 2015, an estimated 2 million people in the US suffered from substance use disorders related to prescription opioid pain medicines (including fentanyl), and 591,000 suffered from a heroin use disorder (not mutually exclusive) The CDC estimates that drug overdoses killed 64,070 people in the US in 2016, a rise of 21% over the 52,898 drug overdose deaths recorded in 2015 NIDA, Research on the Use and Misuse of Fentanyl and Other Synthetic Opioids https://www.drugabuse.gov/about-nida/legislative-activities/testimony-tocongress/2017/research-use-misuse-fentanyl-other-synthetic-opioids, Opioid Overdose Crisis, https://www.drugabuse.gov/drugs-abuse/opioids/opioid-overdose-crisis

41 Opioid Use Disorder (OUD) Opioids activate opioid receptors on nerve cells and in the brain and can produce drowsiness, euphoria, perception of pain relief, mental confusion, nausea, constipation, and, depending upon the amount of drug taken, can depress respiration. Opioid Use Disorder, (OUD) is a physical reliance on opioids including heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone (OxyContin ), hydrocodone (Vicodin ), codeine, morphine, and many others. NIDA, Opioids, https://www.drugabuse.gov/drugs-abuse/opioids,, Opioid Use Disorder (OUD), https://www.samhsa.gov/disorders/substance-use, American Society of Addiction Medicine, ASAM, https://www.asam.org/docs/defaultsource/advocacy/opioid-addiction-disease-facts-figures.pdf

42 OUD & AUD Treatment Options Methadone Buprenorphine (Suboxone and Subutex) Naltrexone (Vivitrol)

43 Barriers to MAT Stigma Insufficient institutional support Insufficient physician knowledge Office staff stigma Low demand Counselors attitudes that drug free is the only way to have recovery Patient s failure to comply with taking medications Payment issues

Homework Technical Support (800) 263-6317 44 What are some of the behavioral indicators or observable signs that indicate possible withdrawal from alcohol? What are some of the behavioral indicators or observable signs that indicate possible withdrawal from opioids?

45 For those sharing a computer, have you typed in your names in the Q & A box? Otherwise you will not receive the evaluation link which you need to receive a certificate of completion. (Clyde, please launch the evaluation link)

46 Medicated Assisted Treatment Enhancing the Potential for Recovery End of Part One Part II will take place next Friday, May 11 th Presenter: Diana Padilla, RCR, CASAC-T Program Manager/Senior Trainer Organizer: Clyde Frederick Technologist/Program Support A follow-up email will be sent to your in-box one hour after part 2 on March 30, 2018. Please complete your evaluation to receive your OASAS Certificate of Completion. It will only take a few minutes. This course provides 3 CASAC hours. Your certificate will be issued in 3-5 business days.