These programs and quantity limitations may not apply. Check your certificate or other plan information for benefit details.

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FlexRx Standard Utilization Management (PA, QL,) Updates January 1, 2018 How to use this drug list This drug list includes updates to Utilization Management (UM) programs. UM may include a prior authorization (PA) requirement, a step therapy () requirement, and/or quantity limitation (QL). For additional information about the various drug programs, you can refer to Bluecrossmn.com. This information is subject to change. Generic drugs are listed in lowercase boldface (e.g., rabeprazole) Brand name drugs are capitalized (e.g., CREOR) Acronyms PA = Prior Authorization, QL = Quantity Limit per 30 days, = Step Therapy Program ± Unless otherwise noted, prior authorization program and quantity limits applies to both brand and generic. Utilization Management Program discontinued 8/30/17 BERINERT PA QL 10 vials (5,000 IU) CINRYZE PA QL 20 vials (10,000 IU) FIRAZYR PA QL 6 syringes KALBITOR PA QL 4 kits RUCONE PA QL 8 vials Utilization Management Program discontinued 12/31/17- Glucose Strip Step Therapy glucose test strips, all manufacturers except Bayer/Ascensia Changes to Existing Utilization Management Program, Effective 1/1/18 ARMONAIR RESPICLICK QL 1 inhaler BEVYXXA QL 43 caps/42 days COTEMPLA XR ODT 17.3 mg, 25.9 mg QL 60 tabs COTEMPLA XR ODT 8.6 mg QL 30 tabs FIASP, FIASP FLEXTOUCH QL 100 ml FLOLIPID 20 mg/5 ml suspension QL 150 ml FLOLIPID 40 mg/5 ml suspension QL 300 ml HUMALOG JR KWIKPEN QL 100 ml IDHIFA PA QL 30 tabs LYNPARZA 100 mg, 150 mg PA QL 120 tabs TRELEGY ELLIPTA QL 60 blisters TYMLOS PA QL 1.56 ml / 30 days VERZENIO PA QL 60 tabs New Utilization Management Program Effective 1/1/18 glucose test strips, all manufacturers except Bayer/Ascensia QL 204 strips New Utilization Management Program Effective 1/1/18- Oral Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Step Therapy ANAPROX (naproxen) ANAPROX DS (naproxen)

ARTHROTEC (diclofenac/misoprostol) CAMBIA CATAFLAM (diclofenac potassium) CELEBREX (celecoxib) CLINORIL (sulindac) DAYPRO (oxaprozin) EC-NAPROSYN (naproxen) FELDENE (piroxicam) FENOPROFEN cap FENORTHO INDOCIN KETOPROFEN cap ER 200 mg MECLOFENAMATE MOBIC (meloxicam) NALFON NAPRELAN (naproxen) NAPRELAN CR (naproxen ext-release) NAPROSYN (naproxen) PONEL (mefenamic acid) TIVORBEX TOLMETIN VIVLODEX VOLTAREN XR (diclofenac sodium ext-release) ZIPSOR ZORVOLEX New Utilization Management Program Effective 1/1/18- Topical Doxepin Prior Authorization (PA) DOXEPIN 5% cream PA QL 45 g every 30 days a PRUDOXIN 5% cream PA QL 45 g every 30 days a ZONALON 5% cream PA QL 45 g every 30 days a a quantity limit is cumulative across agents New Utilization Management Program Effective 1/1/18- Biologic Immunomodulators Prior Authorization with Quantity Limit (PAQL) ACTEMRA PA QL 4 syringes/28 days ENBREL 25 mg/0.5ml PA QL 8 syringes/28 days ENBREL 25 mg/vial, kit PA QL 8 vials/28 days ENBREL 50 mg/ml SureClick autoinjector PA QL 4 autoinjections/28 days ENBREL 50 mg/ml syringe PA QL 4 syringes/28 days CIMZIA 2x200 mg vial, kit PA QL 2 vials (1 kit)/28 days CIMZIA 2x200 mg/ml syringe, kit PA QL 2 syringes (1 kit)/28 days CIMZIA 6x200 mg/ml syringe starter kit PA QL 1 kit/180 days COSENTYX 150 mg/ml pre-filled syringe PA QL 1 syringe/28 days COSENTYX SENSOREADY PEN 150 mg/ml auto-injector PA QL 1 injector/28 days HUMIRA 10 mg/0.2 ml syringe PA QL 2 syringes/28 days HUMIRA 20 mg/0.4 ml, 40 mg/0.8 ml syringe, kit PA QL 2 syringes/28 days HUMIRA 40 mg/0.8 ml pen, Crohn s Starter kit PA QL 1 kit/180 days HUMIRA 40 mg/0.8 ml pen, kit PA QL 2 pens (kits)/28 days HUMIRA 40 mg/0.8 ml pen, Psoriasis Starter kit PA QL 1 kit/180 days HUMIRA 40mg/0.8 ml syringe, Pediatric Crohn's Starter kit (3 syringes) PA QL 1 kit/180 days HUMIRA 40mg/0.8 ml syringe, Pediatric Crohn's Starter kit (6 syringes) PA QL 1 kit/180 days KEVZARA PA QL 2 syringes per 28 days. KINERET 100 mg syringe PA QL 30 syringes/30 days ORENCIA 125 mg/ml (subcutaneous) PA QL 4 syringes/28 days

ORENCIA 50 mg/0.4 ml, 87.5 mg/0.7 ml PA QL 4 syringes/28 days ORENCIA ClickJect autoinjector PA QL 4 autoinjectors per 28 days SILIQ PA QL 2 syringes/28 days SIMPONI PA QL 1 syringe/28 days ELARA 45 mg/0.5 ml PA QL 1 syringe or vial/84 days ELARA 90 mg/1 ml syringe PA QL 1 syringe/56 days TALTZ PA QL 1 syringe/ 28 days TREMFYA PA QL 1 ml (syringe)/ 56 days XELJANZ PA QL 60 tabs XELJANZ XR PA QL 30 tabs New Utilization Management Program Effective 1/1/18- Otezla Prior Authorization with Quantity Limit (PAQL) OTEZLA 10 mg, 20 mg & 30 mg tablet starter pack (two week) PA QL 1 starter kit of 55 tablets/180 days OTEZLA 10 mg, 20 mg & 30 mg tablet starter pack (four week) PA QL 1 starter kit of 55 tablets/180 days OTEZLA 30 mg tabs PA QL 60 tabs

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