May Clinical Director, Peninsula Trauma Network (Edited for PTN)

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Network Policy Traumatic vascular injuries Guidelines Purpose Date May 2015 Version Following the national introduction of Regional Trauma Networks, Major Trauma Networks (MTN s) are required to have a policy for Vascular Trauma. The purpose of this policy is to provide direction and guidance for actions from key individuals and organisations within The Peninsula Trauma Network to improve the patient pathway and ensure that patients are transferred to the definitive point of care as quickly and safely as possible. Who should read this document? PTN and Trauma Network Clinical and Governance Directors TU and MTC Clinical Leads for Major Trauma Trauma Team Leaders Acute Trust Lead Nurses Key messages V1 Accountabilities Production Review and approval Ratification Dissemination Compliance Mr WD Neary (Consultant Vascular Surgeon) Dr N Collin (Consultant interventional radiologist) for the Severn MTN PTN Clinical Advisory Group PTN Executive Board All PTN acute Trusts, All Parties Links to other policies and procedures PTN Trauma Team Activation Policy PTN Safe Transfer of the Critically Ill Patient PTN Secondary Transfer Policy Version History V1 Dr Mark Jadav Clinical Director, Peninsula Trauma Network (Edited for PTN) Last Approval Due for Review 1 year

Management of bleeding and acute ischaemia following trauma Aims: Guide the management of bleeding and acute ischaemia secondary to traumatic vascular injury. Fewer than 10% of patients with polytrauma have associated vascular injuries but these can cause significant mortality and morbidity. Major uncontrolled bleeding remains the leading cause of preventable death in trauma patients (ref 1). A high degree of suspicion of vascular injury and specific exclusion by the trauma team is required. These guidelines include specific recommendations from the European guideline from the multidisciplinary task force for advanced bleeding care in trauma (ref 2) One third of all trauma patients with bleeding arrive in hospital with a coagulopathy (acute trauma coagulopathy (ref 3) and the management of this must be in parallel with the control of anatomical vascular injuries. Vascular injuries may have significant sequel, acute haemorrhage may be overt, contained (muscle compartment) or concealed (e.g. pleural cavity). It may be immediate or delayed with rebleeding. A contused artery may be initially patent but later thrombose and so ischaemia may be acute or delayed. Control of haemorrhage and restoration of perfusion are key to the resolution of vascular injury. Diagnosis History- the mechanism of injury, blood loss prior to hospital and underlying previous vascular disease should be sought when possible. Examination Assessment should be carried out according to ATLS principles and life threatening conditions should be managed. Vascular injuries may present with hard or soft signs Hard signs Soft signs Active pulsatile bleeding Shock with ongoing bleeding Absent distal pulses Signs and symptoms of acute ischaemia Expanding haematoma Thrill or Bruit History of severe bleeding Diminished distal pulse Injury of anatomically related structure Multiple fractures and extensive soft tissue injury Injury in anatomical area of major blood vessel

Extensive soft tissue swelling may make evaluation difficult but a diminished or reduced distal pulse is due to arterial occlusion until proven otherwise. A concern raised of significant vascular injury from the mechanism, assessment or investigations should prompt contact with the on call vascular consultant via switchboard. Management principles in haemodynamically stable patients with suspected peripheral vascular injuries Patients with a normal vascular examination and Ankle brachial pressure index of >0.9 may be discharged if otherwise well. Patients with an abnormal vascular physical examination or an ABPI < 0.9 require arterial imaging Once vessel injury with distal circulation compromise is detected the on call vascular surgeon should be contacted. Patients with hard signs of arterial injury need the network on call vascular surgeon contacting as soon as possible, further imaging may not be required to confirm management Patients with hard signs of arterial injury (pulsatile bleeding, bruit thrill, expanding haematoma should be surgically explored and repaired, restoration of perfusion to an extremity with an arterial injury must be performed in less than six hours, faciotomies should be performed liberally if there is any significant concern that compartment syndrome may occur (prolonged ischaemia or significant soft tissue injury) Investigations CT angiography is used as the primary diagnostic study in patients with a suspected vascular injury Patients whose mechanism of injury or pre hospital history includes hard signs of vascular injury should be discussed early with the on call vascular consultant as soon as possible so that plans to access theatres may get underway in readiness for the patients arrival. Patients in whom the vascular injury becomes evident on clinical assessment or imaging and is life or limb threatening should be discussed with the on call vascular consultant through switchboard.

Major trauma patients with massive haemorrhage at vascular spoke hospitals (as per local agreements) 1. Patients presenting with life threatening post trauma haemorrhage will not bypass their local hospital that has the capacity to stop it. Their life threatening haemorrhage will be treated in the first major hospital they pass, after this has been dealt with they will be admitted to the Major trauma and arterial centre for ongoing management. 2. If the patient has been admitted to their local hospital and their haemorrhage only becomes evident whilst an inpatient the availability of a surgeon with vascular expertise should not prolong haemorrhage- the priority is control of bleeding 3. Recommended treatment consists of rapid laparotomy (if intra-abdominal) and control of haemorrhage using direct pressure or arterial clamps until a local surgeon with vascular experience arrives. 4. The role of the local surgeon with vascular experience is to repair, reconstruct or ligate the artery or vein that is bleeding (veins are usually safer ligated) 5. The on call vascular surgeon should be contacted and will either: Offer advice; bleeding can be profuse without injury to a major vessel. Many vessels can be simply ligated and this is well within the remit of a surgeon of any speciality Attend in person: Unless there is a vascular surgeon on site Transfer Patient: This only becomes an option once the haemorrhage is controlled and the patient is haemodynamically stable Principles of resuscitation and prevention of further bleeding The time between injury and procedure to stop the bleeding should be minimalized. (Over half of trauma deaths occur within 24 hours of injury (ref 4)) Tourniquets can be used to stop life threatening haemorrhage pre surgery, This is a simple and effective method to acutely control haemorrhage, the time span for there removal should be as short as possible but can be 2-4 hours. Especially with mangled extremities they are superior to pressure bandages (ref 5)

The physician should clinically assess the extent of traumatic haemorrhage using mechanism of injury, patients physiology, anatomical injury pattern and patients response to resuscitation Patients with haemorrhagic shock and an identified bleeding source need immediate bleeding control unless resuscitation is successful Patients with haemorrhagic shock and an unidentified bleeding source require immediate assessment of the chest, abdominal cavity and pelvis both clinically and with X-ray of chest, pelvis and abdominal sonography (FAST scan). If CT is readily available it may replace the above investigations (ref 3) Patients who are stable haemodynamically but have thoracic and abdominal injuries need early FAST scan and those who have fluid detected need CT. Patients who are suspected clinically of having thoracic or abdominal bleeding who have a high risk mechanism of injury require CT Initial haematocrit level has a low sensitivity of detecting those patients needing surgical intervention, it should be performed but normal value must not reassure the clinicians. Serum lactate and base deficit should also be taken. Post traumatic coagulopathy is common and should be assessed using thromboelastogram based methodology where available. Close liason with the haematologist with the use of massive transfusion protocol should occur. Patients with pelvic ring disruption in haemorrhagic shock require immediate pelvic stabilisation. Patients bleeding from the pelvis despite stabilisation require early pre peritoneal packing. Ongoing abdominal, pelvic or thoracic bleeding that CT assessment suggests is treatable endovascularly should receive this intervention rapidly. Hard signs of intra thoracic bleeding require thoracotomy, if done as an emergency by the general or vascular surgeons at the MTC then the thoracic surgeons should be informed via switchboard and will attend as soon as possible. Thoracic arterial injuries that become evident on CT imaging should be discussed with the on call vascular, interventional radiology and thoracic surgical consultants. If

considering transfer from the trauma unit, first call the MTC Trauma Team Leader who will coordinate a timely response. If abdominal bleeding is not treatable endovascularly or if there are other abdominal injuries requiring surgery then early control should be with abdominal packing and damage limitation surgery. Ongoing active bleeding intraoperatively despite packing is an indication for aortic cross clamping.

Reference 1. Vascular Trauma Chapter 10 Vascular and Endovascular Surgery A companion to specialist surgical practice. Jacobus van Marle and Dirk a. le Roux 2. Management of bleeding following : an updated European guideline Critical Care 2010 14:R52 http;//ccforum.com/content/14/2/r52 Rosaint et al 3. Standards of practice and guidelines for trauma radiology in severely injured patients The Royal college of radiologists Dec 2010 4. Epidemiology of urban trauma deaths; a comprehensive reassessment 10 years later. World J Surg 2007 31;1507-1511 Cothren CC, More EE, Hedegaard HB, Meng K 5. 5. Tourniquets for haemorrhage control on the battlefield; a 4 year accumulated experience J Trauma 2003 54 S221-225 Lakstein D et al. 6. Bristol Bath Weston Vascular Network Statement of Clinical Advice. Major vessel injury. Brooks, M Mitchell D, Collin N 2014