FRiSCy Oxford Fracture Prevention Service

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FRiSCy Oxford Fracture Prevention Service MK Javaid Lecturer in Metabolic Bone Disease, University of Oxford Hon Consultant Rheumatologist, Nuffield Orthopaedic Centre Lead Clinician for FRiSCy

Declaration These views are my own In last five years received honoraria, travel and/or subsistence expenses from: Amgen, Eli Lilly, Medtronic, Norvartis, Proctor and Gamble, Servier, Shire

Mapping to Public Health Responsibilities making the public healthier by encouraging discussions, advising government and supporting action by local government, the NHS and other people and organisations supporting the public so they can protect and improve their own health protecting the nation s health through the national health protection service, and preparing for public health emergencies sharing our information and expertise with local authorities, industry and the NHS, to help them make improvements in the public s health researching, collecting and analysing data to improve our understanding of health and come up with answers to public health problems reporting on improvements in the public s health so everyone can understand the challenge and the next steps helping local authorities and the NHS to develop the public health system and its specialist workforce

Mapping to Public Health Priorities helping people to live longer and more healthy lives by reducing preventable deaths and the burden of ill health associated with smoking, high blood pressure, obesity, poor diet, poor mental health, insufficient exercise, and alcohol reducing the burden of disease and disability in life by focusing on preventing and recovering from the conditions with the greatest impact, including dementia, anxiety, depression and drug dependency

Lifetime fracture risk in 50 white men and women Men (%) Women (%) Hip 10.7 22.9 Clinical vertebral 8.3 15.1 Distal forearm 4.6 20.8 Humerus 4.1 12.9 Any of above 22.4 46.4 Lifetime risk for Wrist/ Hip or vertebral is 30-40% (similar to CHD)

After a HIP fracture: More bed days than heart attack and stroke combined 50% require care home admission 1:10 dead 1 month 1:3 dead by 12 months 2.3 billion in hip fracture costs alone per year

2.3 billion / years more bed days than heart attack and stroke combined 340,00 fragility fractures last year > 68,000 Hip fractures last year > Each hip fracture costs 30K/2 years (NHFD 2010) DoH 13081 2009

2.3 billion / years more bed days than heart attack and stroke combined 340,00 fragility fractures last year > 68,000 Hip fractures last year > Each hip fracture costs 30K/2 years (NHFD 2010) 50% have already had a fracture Drugs cost from 11 per year RCT demonstrate reduced risk of re-fracture by 20 70% DXA scan costs 69 DoH 13081 2009

Relatives Carers Patients with fragility fracture Live longer Independence Medicine waste Step change in local and national care Fewer fractures in your constituency MORE resource to spend on UNavoidable illness Fewer care home beds Lower demand for Community Physiotherapy Fewer GP visits Fewer Delayed Discharges Fewer NHS trust admissions Free up Ambulance time Lower A&E waiting times

Primary or secondary prevention

Limited resource: maximize value ORTHOGERIATRICS 16% population 50% FLS FALLS 74% population 50%

50% hip fracture patients have already had a fragility fracture A fragility fracture Doubles risk of fracture After the first fracture, act to prevent the second

Less than 50% of fracture patients are assessed for osteoporosis AND YET Less than 50% of patients who start treatment are still on it at 1 year Treml 2012

Achieving the outcome Find them Assess them Decide which treatment Make sure they stay on it Norman 2008

High value GP Hospital EVERY ONE CONTRIBUTES > 3mth delay > 30% DNA RATE > 50% Non adherence

Delivered within Primary care: QOF 2012/13 300,000 closed fractures per year 250,000 fragility % Osteoporotic 125,000 > 75 years 100% 125,000 Osteoporotic 62,500 64-75 years 31,250 Osteoporotic 62,500 60-74 years 50% 25% 15,630 Osteoporotic 171,880 Osteoporotic 42,242 patient found 60-100% on treatment MISSED treatment in 129,880-146,534 (72-85%) of eligible patients

The NHS pathway Trauma surgeon Geriatrician Fragility Fracture Hospital Rheumatology GP Clinical Chemistry Endocrinology Secondary Fracture Prevention Already paying for finding and treating Hip fracture best practice tariff Un-provided other inpatient fracture (50%) & all outpatient fracture patients

The Effective Service Fragility Fracture Hospital Dedicated Fracture Prevention Service Secondary Fracture Prevention Minimally disruption healthcare Public health, primary or secondary care led but must be patient focused

A therapy for every patient (annual cost) ORAL Alendronate 70 mg weekly ( 11.44) Risedronate 35mg weekly ( 15.21) Ibandronate 150 mg monthly ( 18.98) Strontium 2g nocte ( 353) Calcium replete Vitamin D replete Zoledronate 5mg iv annually (day case rate) Denosumab 60mg sc 6m ( 366) Treatment adherence options with parenteral therapy Teriparatide 20mcg od s.c ( 3263)

Fracture Reduction in South Central PolicY group A network of every bone clinician/ Nurse AIM: Every patient with a fragility fracture over the age of 50yr in South Central is: 1. Identified 2. Assessed 3. Treated effectively for at least five years for both bone and falls health Fracture Liaison Service > Fracture Prevention Service POSITIVE LIBERTY- We choose the scope of what we can decide

Case find Assessment Treat initiation Monitoring Minimize patient burden Interface service Trauma case finding + community monitoring Transfer care from high cost specialist settings to lower cost community settings Integrated care Cost effective Safety Patient Experience

Trauma ward patient Trauma clinic patient Pelvic fracture Medical patient Spine fracture General patient Hospital based Community based UNDER 75 years OVER 75 years DXA Assess & Treat Assess & Treat Recommend to Patient and GP Falls & Generations Game Care Home Dementia Renal Care 3 & 12 months Monitor

1. Performance PCT 2. Finance 3. IT database 4. PDSA Project manager Clinical lead Nursing Lead 1 Admin OP non FPS 1. Clinical pathway 3. Training 3 nurses 0.5 Aux nurse 1.5 Admin 600,000 population 2 hospitals 1. Case finding 2. Assessment - Questionnaire 3. Assessment - examination 4. Assessment - blood results 5. Treatment pathway 6. Monitoring assessment 1. Case finding 2. Phlebotomy 6. Monitoring assessment 1. Appointments 2. GP / patient letters 3. Monitoring assessments

Number of Patients Secondary fracture assessments by month 300 250 200 150 100 50 0 J F M A M J J A S O N D J F M A M J J A S O N D J F M A M J J A S O N D J F 600,000 population 2 hospitals 2011 (151/mth) 2012 (186/mth) (2,226) N= 5786 2013 (224/mth) (2,689)

Percentrage of treated patients Fracture Prevention Specialist Nurse Recommendation (n=3,680) 80% 70% 60% 50% 40% 30% 2011 2012 2013 2014 20% 10% 0% Alendronate Denosumab Risedronate Strontium Zoledronate PTH

Percentage of Patients Outcome of monitoring 100 80 60 40 78% 56% 3m (n=945) 12m (n=292) 20 0

Mapping to public health Responsibilities making the public healthier by encouraging discussions, advising government and supporting action by local government, the NHS and other people and organisations supporting the public so they can protect and improve their own health protecting the nation s health through the national health protection service, and preparing for public health emergencies sharing our information and expertise with local authorities, industry and the NHS, to help them make improvements in the public s health researching, collecting and analysing data to improve our understanding of health and come up with answers to public health problems reporting on improvements in the public s health so everyone can understand the challenge and the next steps helping local authorities and the NHS to develop the public health system and its specialist workforce

Mapping to public health Priorities helping people to live longer and more healthy lives by reducing preventable deaths and the burden of ill health associated with smoking, high blood pressure, obesity, poor diet, poor mental health, insufficient exercise, and alcohol reducing the burden of disease and disability in life by focusing on preventing and recovering from the conditions with the greatest impact, including dementia, anxiety, depression and drug dependency

Set the outcome: need to ensure all fragility fracture patients over 50 years have 4 steps TOP Find them Assess them Decide which treatment Make sure they stay on it BOTTOM Champion network: Work out how much and how to do this for the locality

Summary Set the standards and priorities Population approach across 4 steps High value interventions Bone health and falls to reduce fracture

Kerri Rance Sally Hope Sarah James Terri Morgan Carol Weeks Rachael Knight Tracy Dobbin Rhys Davies Suzanne Jones/ Sylvie Thorn Professors Cooper, Wass, Willett, Arden, Carr D Prieto Alhambra, A Judge, R Batra, G Round, A Kiran, K Leyland, A Soni, R Warne And all the FRiSCy team! Stephen, Colin, Annie, Gill, Mark ElevenInformatics: John, Naveed & Joanna Adam Dawroski / Antoinette Broad