China Orthopedics Implants Medical Devices Market Brief

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China Orthopedics Implants Medical Devices Market Brief By: PIM LTD. August 2017 reproduced for distribution outside the client organization without prior written approval from PIM Ltd. 1

Definition and Classification 1,2 Orthopedics implants medical devices are the clinical orthopedic medical materials used for human skeleton replacing, supporting and repairing. Commonly, there are three main types: joint, spinal and trauma products. Joints Products Shoulder system Elbow system Hip system Tissue-sparing Resurfacing Femoral stem Revision system Upper extremities Limb salvage Knee system Primary total knee System Patient specific Revision knee Source: 1. China Association for Medical Devices Industry 2. PIM Research and analysis Spinal Products Spinal fixator Pedicle screw Coupling device Anterior cervical/ Thoracic/ Lumbar vertebra fixation system Bone plate splint Screw Posterior cervical fixation system Steering pin Cervical spine Locking plate Coupling device Trauma Products Bone plate splint T-Shaped bone plate Golf club-like shape bone plate L-Shaped bone plate Bone remodeling plate Hollow rivet Screw Bone nail Dynamic hip screw 2

Demand Growth 1,2,3 Number of orthopedic patients in China is on the rise Number of osteoporosis patients in China is estimated to increase to 0.2866 billion in 2020. By 2016, China had over 0.2 billion patients with cervical syndromes and had spent around 0.5 billion on it. Number of osteoporotic hip fracture patients in China is projected to be 1.6382 millions in 2020. The index on Chinese knee-joint health is only 64.7 points and nearly 30% are less than 60 points out of 100 in 2017 Source: 1. 2017 BY-HEALTH National Health Report 2. PIM Research and analysis 3. Chinese Journal of Joint Surgery 2014, (3) 3

Market Drivers Government Policies 1, 2 13th Five-Year Science and Technology Innovation Planning At present, the research and application should also focus on bone-like implants and implant devices aspect In the aspect of strategic layout, the new generation of implants medical devices, artificial organs tissue engineered medical products and tissue induced biomedical materials should be key development part. Subject plan for the 12th Five-year Plan of the Medical Device Technology Industry Orthopedics implants products, are listed as national key products development Beef up the spread and application of high-and-mid-end and main popular medical device, intravascular stent and artificial joint that depends on importing The 13th Five-Year Plan High performance medical devices, like high-value medical consumables and diagnostic imaging equipment will be the focus of policy support in the future Source: 1.Ministry of Science and Technology of the PRC 2. Pharmnet.com.cn 3.www.Sohou.com 4

Market Shares on Orthopedics Implants Medical Devices 1,2 350 300 250 200 150 100 50 0 Trauma Implants Market Joint Implants Market 139 24 49 117 22 40 98 19 84 33 17 72 27 55 15 21 46 14 17 39 14 33 20 24 28 24 28 32 38 45 53 61 2010 2011 2012 2013 2014 2015 2016 2017E 2018E 2019E 100 Million CNY Source: 1.PIM research and analysis, August 2017 2.www.chyxx.com 3. * Others= Sports Medicine + Neurosurgery Spinal Implants Market Others 163 192 27 227 29 62 65 71 266 29 77 77 83 311 26 96 91 98 In overall market, the China Orthopedics Implants Medical Devices keep increasing and is estimated to be 31.1 billions in 2019 Every specific orthopedics implants medical devices market is witnessing the increasing situation Trauma Implants Market is always the largest market section from the year 2010 to 2019E The Joint Implants Market grows quicker than the others (Average grow rate of it is more than 20%) 5

Leading Brands 1,2 Worldwide Orthopedics Sales, Market Share & Sales Growth of Leading Brands (2015~2022E) * : J&J and Zimmer Biomet are the leading companies in Orthopedics in 2022 with Zimmer Biomet set to experience strong growth Worldwide Market Share % in 2022 Source: 1. EvaluateMedTech 2. PIM Research and analysis Note: * Bubble size = worldwide sales in 2022 6

Thank you! 谢谢! Building 1 Suite 1362, #59 Mao Ming Nan Lu, Huangpu District Shanghai 200020 China Tel: +86-21-5466 7100 Fax: +86-21-5466 7110 www. pimchina.com