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1380 مريم نخشب(. M.D )* قاسم بياني(. M.D )** محمد اسحاقي تيموري(. M.D )*** چكيده سابقه و هدف احمد احمدزاده اميري(. M.D )*** ROP (Retinopathy Of Prematurity) :.. مواد و روش ها : -. ( ) /.. يافتهها : ROP ( / ) / ROP ROP. ROP. ( / ).. ROP Pco2 استنتاج : ROP. ROP واژه هاي آليدي : -.( ) مقدمه (ROP).( ). - - : *** / / : * ** / / : / / : 63 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران

شيوع رتينوپاتي نوزادان نارس ROP.( ) (IC ROP) ( ) ROP.( ).( ) ROP.( ). ROP.( ) ROP : ROP -. ROP.( ) -.( ) ( ) Terry (RLF). ( ).( ) ROP. ( ) ROP ( ).( ) (LBW).( ) ( ) / /.( ) ROP ROP.( ) PDA E RDS Pco2 Pco2 1. Retrolensal Fibroplasia 2. Low Birth Weight 3. Ablation 64 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران

: ROP (. NICU (. ROP. مواد و روش ها. - NICU : (LBW) ( ) (. ( NICU) (.. ( ) ). (.. ). - ROP. ROP.( ). ROP ( ) ]. [.( ) ROP.( ) ROP.( ) 1. Neonatal Intensive care unit. 65 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران

شيوع رتينوپاتي نوزادان نارس.. Z يافتهها. ROP ( / ) ( / ).. pretreshhold plus. IUGR.. ) (ROP ROP ROP.. ROP ROP ROP.. ROP ROP.. ( + +.( ) ROP ROP.( ) CRYO ROP : ROP Hct Pco2 PH Pco2. Ballard LMP..( ) (RDS Score).( ) E..... 66 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران

. ROP. NICU..( ) ( ).( ) ( ).( ). NICU NICU ROP. / ROP ROP. ( ).. PH Pco2. ROP ( P< / ) ( P< / ) ROP ( P< / ) Pco2. : P value * < / < / < / ROP / ± / / ± / / ± / / ± / ( %) ( %) * NonSIGNIFICANT ( ) ROP ± / ± / / ± / / ± ( / %) ( %) / ± / ± / / ± / / ± / / ± / ( / ) ( / %) ( ) ( ) (%) ( ) (mg/dl) PH (mmhg) Pco2 (mmhg) Pco2 n( ) ( ) بحث ROP / ROP / ( ). ROP ( ) Hussain ( ) / ROP.( ) / ( ) 67 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران

شيوع رتينوپاتي نوزادان نارس ROP.( ) ( ) ROP.( ). ROP ROP. ROP..( ) ROP ( ) ROP ROP (goggles).( ).( ) ( ) ROP. ROP ROP. / ( ) Hussain..( ). ROP ROP ROP ROP.. ROP ROP.( ).. ROP ( ROP ) ( ) Rhi Gilbert - ROP ROP ) ( ( ) ROP ROP. AAP (AAP ). 68 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران

ROP. ROP ROP RDS ( ) ROP..( ) ROP ROP.. ROP 1. American Academy of Pediatrics Screening Examination of Premature Infants for Retinopathy of Prematurity- Ped. 2002 Sep; 108(3): 809-811. 2. Fanarroff, Avroy A, Martin Richard J. Neonatal-Perinatal Medicine.7 th ed.missouri: Mosby co; 2002: 1595-1599. 3. Gomella Tricia Lacy Cunningham M. Douglas Eyal Fabien G-A LANGE clinical mannual Neonatology 4 th ed. California: APPLETON & LANGE co; 1998: 520-523. 4. Klaus Marshall H. Fanarroff Avory A. Care of the high risk neonate 5 th ed. Paco2 ) ROP (..( ).( ) ROP co2 Co2.( ) Pericyte.( ) (permissive hypercapnia).( ) (RDS Scoring) فهرست منابع Philadelphia: WB Saunders co; 2001: 246-249. 5. The STOP-ROP-Multicenter Study Group- Supplemental Therapeutic Oxygen for Prethreshhold Retinopathy of prematurity (STOP-ROP), A Randomized, Controled Trial-I: primary outcomes. Pediatrics. 2000 Feb; 105(2): 295-309. 6. Hussain Navid, Clive. Jonathan- Bhandari, Vineet. Current Incidence of Retinopathy of prematurity, 1989-1997- Pediatrics. 1999 Sep; 104(3): 26-38. 7. Yeo Kim Lian, Perlman Max, Hao Yond, Mullaney Paul, outcomes of extremely 69 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران

شيوع رتينوپاتي نوزادان نارس premature infants related to their peak serum Billirubin concentrations and exposure to phototherapy - Ped. 1998 Dec; 102(6): 1426-1430. 8. Mccolm J.R. Fleck B.W. Retinopathy of prematurity: Causations. Seminars in neonatology. 2001 Dec; 6(6): 453-461. 9. Mittal Madhur.Dhanireddy Ramasobbaraddy. Higgins Rosemary D. Candida sepsis and association with Retinopathy of prematurity. Pediatrics. 1998 Apr; 101(4): 654-657. 10. Fielder A.R. Reynolds J.D. Retinopathy of prematurity: clinical aspects. seminars in neonatology. 2001 Dec; 6(6): 461-477. 11. Gilbert C, Rahi J, Eckstein M, Retinopathy of prematurity in middle income countries.lancet.1997;350:12-14. 12. Siatkowski RM, Flynn J T. Retinopathy of prematurity. In: Nelson L, ed. Harleys Pediatric Ophthalmology.4 th ed.philadelphia, PA: W B Saunders & CO; 1998; p 956-958. 13. The committee for the classification of Retinopathy of prematurity: An International classification for Retinopathy of prematurity. Arch Ophthalmology. 1990; 108: 195-204. 14. Palmar EA, Flynn JT, Hardy RJ, Incidence and course of Retinopathy of prematurity. Ophthalmology 1991; 98: 1628-1640... ( ) -.. -. -. - - 17. Savgstad OD. Mechanisms of tissue injury by oxygen radicals: implications for neonatal disease. Acta Paediatr. 1996; 85: 1-4. 18. Belanger S, Lavoie J-C, Chessex P. Influence of Billirubin on the antioxidant capacity of plasma in newborn infants. Biol Neonate. 1997; 71: 233-238. 19. Reynolds JD, Hardy RJ, Kennedy KA, Lack of efficacy of light reduction in preventing Retinopathy of prematurity. N Eng J Med. 1998; 338: 1572-1576. 20. Shohat M, Reisner SH, Krikler R, Retinopathy of prematurity: Incidence and Risk factors. Pediatrics. 1983; 72: 159-163. 21. Mariani G, Cifuentes J, Carlo WA. Randomised trial of permissive hypercarbia in preterm infants. Pediatrics 1999; 104: 1082-1088. 70 مجله علمي- پژوهشي دانشگاه علوم پزشكي مازندران