EUROHOPE: Hip fracture in Europe are slippery regions different? 25 Sep, 2012 Emma Medin Karolinska Institutet, Stockholm, Sweden
Hip fracture is the most common fracture and associated with increased mortality A hip fracture is a femoral fracture that occurs in the proximal end of the femur (the long bone running through the thigh), near the hip In the vast majority of cases, a hip fracture is a fragility fracture due to a fall or minor trauma in someone with weakened osteoporotic bone Hip fractures are associated with increased mortality rates and patients are at increased risk for premature death for many years after hip fracture (Abrahamsen 2009) Hip fractures, account for 63%-72% of hospital admissions for fracture in patients over the age of 50 years (Johnell et al 2005; Kanis et al 2011) and place a significant burden on the hospital system
The incidence of hip fracture varies across different countries A variety of studies have examined hip fracture rates in different regions of the world (Kanis 2006) The highest risks of hip fracture are seen in Norway, Sweden, Iceland and Denmark Germany, Switzerland, Finland, Greece, The Netherlands, Hungary, Italy, the UK and Portugal have been described as high risk countries defined as having a hip fracture probability that lies between 50% and 75% of the risk that is observed in Sweden
The study aims to identify potential cross country differences and best practices This study is aiming at comparing quality and costs in the treatment of hip fracture in Europe And to explore the reasons behind differences in health outcomes and resource utilisation Treatment practices and guidelines (e.g. time to surgery) Type of surgical procedure used Organisation of health care Patients > 50 years of age that are surgically treated and has one of the following diagnoses are included: Collum fracture (S72.0) Pertrochanteric fracture (S72.1) Subtrochanteric fracture (S71.2) Patients with a hip fracture in the previous 365 days are excluded
The incidence of surgically treated patients was highest in Sweden in 2007, then come Hungary No of patients Total population Incidence (per 100 000 population) Sweden 12 136 3 411 896 355.7 Hungary 11 314 3 677 570 307.6 Finland 5 153 2 016 030 255.6 Across all three countries approx. 30% of patients are men and 70% are women
In Sweden 70% of patients are aged 80 years or above, in Finland 59% and in Hungary 48% 60 50 40 % 30 20 Sweden Finland Hungary 10 0 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 > 90 Age groups The median age is 84 years in Sweden compared to 81 in Finland and 79 in Hungary
Across the board the vast majority of patients are admitted from home and few has suffered a previous hip fracture 84 % of the Swedish patients and 72% of the Finnish patients are admitted from home Patients with a hip fracture within the past 3 years: 4.1% of the Swedish patients 3.4% of the Finnish patients 2.8% of the Hungarian patients
The most important co-morbidities are hypertension and depression Atherosclerosis Stroke COPD and asthma Comorbidity Dementia Coronary artery disease Diabetes mellitus Hungary Finland Sweden Depression Hypertension 0.0 10.0 20.0 30.0 40.0 50.0 60.0 70.0 %
The vast majority of patients suffers from a fracture in the neck of femure 100 % 90 % 10.2 7.0 6.4 80 % 70 % 60 % 48.4 31.0 53.4 50 % 40 % Subtrochanteric Pertrochanteric Neck of femur 30 % 62.0 20 % 41.4 40.2 10 % 0 % Sweden Finland Hungary
Internal fixation with gamma nail is the most common surgical procedure used Internal fixation of fracture of upper femur with screws and sideplate Surgical procedure Internal fixation of fracture of neck of femur with nail or screw Internal fixation of fracture of other parts of femur with plate Primary partial prosthetic replacement of hip joint using cement, other or unspecified Hungary Finland Sweden Internal fixation of fracture of upper femur with gamma nail 0.0 10.0 20.0 30.0 40.0 50.0 60.0 %
Mean mortality rates; 30- day, 90-day and one-year (adjusted for age and sex) 50 % 45 % 40 % 41 % 35 % 30 % 25 % 25 % 24 % 23 % 20 % 15 % 13 % 14 % 12 % 10 % 5 % 8 % 7 % 0 % 30-day 90-day one-year Finland Hungary Sweden
70 % One-year mortality per region by country (adjusted for age and sex, with confidence intervals) 60 % 50 % 40 % 30 % 20 % 10 % FINLAND HUNGARY SWEDEN 0 %
Mean length of stay of first hospital episode 70 D a y s 60 50 40 30 20 Other hospital inpatient care in first hospital admission Surgery admission 10 0 Finland Hungary Sweden
Days Mean leanght of stay during first hospital episode and the first year (adjusted for age and sex) 100 90 80 70 60 87.00 50 45.55 40 30 20 10 22.2 22.4 13.9 16.6 0 Length of first hospital episode Hospital days during the first year Finland Hungary Sweden
Mean length of stay first hospital episode per region by country (adjusted for age and sex, with confidence intervals) 90 Days 80 70 60 50 40 30 20 10 0 FINLAND HUNGARY SWEDEN
So, cross-country differences in quality and resource utilisation exists Differences of incidences are in line with other sources Slippery regions in general don t seem to be different Osteoporosis (and related diseases) that is claimed to be a main comorbidity is only found in less than 2% of the patients Hypertension and depression are the most common comorbidities The share of patients above 80 years is largest in Sweden. Still, one year mortality is the lowest, and And length of stay is the shortest However, at the regional level The mortality rates are similar to them of Finland, and Length of stay is similar to them of Hungary Next steps includes further analyses of reasons behind the identified differences Differences in post- surgical care (e.g. organisation of rehabilitation) Differences in clinical guidelines (e.g. time to surgery)