Ali Mohammad Saleh Al- Amri

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Ali Mohammad Saleh Al- Amri Professor Personal Data Nationality Saudi Date of Birth 28/11/1962 Department Internal Medicine Official UoD Email amalamri@ud.edu.sa Office Phone No. +96613-8966741 Language Proficiency Language Read Write Speak Arabic Yes Yes Yes English Yes Yes Yes Academic Qualifications (Beginning with the most recent) Date Academic Degree Place of Issue Address 4/5/2002 Medical oncology fellowship- UBC Saudi Council for Health Saudi Arabia qualified as Saudi Fellowship Specialties 6/30/2001 Medical Oncology Fellowship- UBC University of British Columbia, Canada Vancouver Cancer Center 5/5/1997 Arab Board in Internal Medicine (ABIM) equal to Saudi board and PHD Saudi Council for Health Specialties Saudi Arabia 9/16/1995 Arab Board in Internal Medicine (ABIM) King Faisal University Saudi Arabia 10/4/1989 MBBS King Faisal University Saudi Arabia 3/7/1996 Medical Council of Canada Evaluating Examination for graduates of International Medical schools 7/20/1998 MRCP1 Ottawa, Ontario Canada

PhD, Master or Fellowship Research Title: (Academic Honors or Distinctions) Fellowship Winner of the prize of The Best Poster presentation by fellow at Resident Research Day. May 23/ 2001 Vancouver Cancer Center, BC Professional Record: (Beginning with the most recent) Job Rank Place and Address of Work Date From To Associate professor of medicine and medical oncology Medicine/Medical Oncology/ Internal Medicine University of Dammam/Saudi Arabia 2/17/2010 Present Assistant Professor of Medicine and Medical Oncology Consultant Internist/ Medical Oncologist Fellow in Medical Oncology Specialist (Senior Registrar) Chief Resident in internal medicine Resident in internal medicine Intern, rotating internship Medicine/Medical Oncology/ Internal Medicine Medicine/Medical Oncology/ Internal Medicine Medical oncology Internal Medicine Medical Oncology Medical Oncology Medical Oncology University of Dammam/Saudi Arabia University of Dammam/Saudi Arabia University of British Columbia/Vancouver Cancer Center KFU/King Fahd Hospital of the University KFU/King Fahd Hospital of the University KFU/King Fahd Hospital of the University KFU/King Fahd Hospital of the University 2005 2010 2001 2005 1999 2001 1996 1999 1995 1996 1990 1995 1988 1989 Scientific Achievements Published Refereed Scientific Researches (In Chronological Order Beginning with the Most Recent) # Name of Investigator(s) Research Title Publisher and Date of Publication 1 Abdullah K. Al- Hwiesh, Nadia Aloadh, Ibrahiem S. Abdul- Rahman, Bander Al- Dhafery,Ali M. Al- Amri, Fahad A. Almuhanna. Transport Characteristic of patients on automated peritoneal dialysis may not affect their lipid profile. Saudi Journal of Medicine & Medical Sciences 2013;1(2): 82-87 * 2 Al- Amri AM. Future Saudi doctors and cancer patients agree cancer patients should be informed about their cancer. 3 Al- Amri AM. Management of metastatic breast cancer (MBC). Asia Pac J Clin Oncol. 2013 ;9(4):342-8 * Gulf Journal of Oncology 2013;13:61-66. * 4 Alenzi FQ, Al- Amri AM, Alanazi FG, Cellular and molecular responses of J Ayub Med Coll Abbottabad

# Name of Investigator(s) Research Title Publisher and Date of Publication Tammimi W, Alanazi A et al. saudi cml patients to imatinib 2012;24(2):122-8. * (sti571); ten year experience. 5 Ibrahim Saeed Abdulrahman, Al- Amri AM. Castle man disease, review article. Korean J Hematol 2012;3(47):163-177. * 6 Ali M. Al- Amri. Pattern of thyroid cancer in the eastern province of Saudi Arabia: Journal of cancer therapy 2012; 3:187-191. * University hospital experience. 7 Ali M. Al- Amri. False belief about etiology of cancer. Life Sci J 2012;9(3):2280-2282. * 8 Ali M. Al- Amri, Shawarbi MA, Al- Hassan AY, Al- Johi KS. Gastrointestinal stromal tumors (GISTs): Case report and review of the literature. 9 Ali M. Al- Amri. Attitude of Saudi medical students toward the disclosure of information on cancer in eastern Saudi Arabia. 10 Ali M. Al- Amri. Breast carcinoma in pregnancy and lactation: Adiagnostic and therapeutic dilemma. 11 Ali M. Al- Amri. Middle Saudi cancer patient s attitude toward disclosure of cancer information. 12 Ali M. Al- Amri. Long term survival of gastric adenocarcinoma without therapy: Case report. 13 Ali M. Al- Amri, Abdulrahman IS, K. Q. Ghallab. 14 Ali M. Al- Amri, Mohammad A. Shawarby, Sana M. Al- Solami, Khalda S. Al- Johi. 15 Dalal M. Al- Tamim, Philip S. Bernard, Mohamed A. Shawarby, Ali M. Al- Amri, Castleman s disease:a study of a rare lymphoproliferative disorder in a university hospital. Evaluation of HER- 2 overexpression of breast cancer at teaching hospital. Maha Abdel Hadi. Distribution of Molecular Breast Cancer Subtypes in Middle Eastern- Saudi Arabian Women: A Pilot Study. 16 Ali M. Al- Amri, Mir Sadat Ali. Cancer chemotherapy induced osteoporosis: How common is it among Saudi cancer survivors. 17 Ali M. Al- Amri. Shiraz E Phase I safety and clinical activity of thymoquinone in patients with metastatic carcinoma. 18 Ali M. Al- Amri. WHO Cancer patients desire for information: results from study in KSA teaching hospital. 19 Samir H. Al- Mueilo, Ali M. Al- Renal failure in patient with multiple Amri. myeloma: a single center experience. Gulf Journal of Oncology 2011;1(9):57-60. * J Family and Community Med 2011;18(2):54-58. * IJCRIMPH 2011;3(7):542-548. * East J Cancer 2010;1(14):175-180. * Oman Medical Journal 2010;25(4):303-305. * Gulf Journal of Oncology. 2010;7:25-36. * The Breast J 2010;16(2)211-212 Ultrastruct Pathol 2009; 33(4):141-50. Indian Journal of cancer 2009;46(4)331-334 Medical Journal. 2009;10(3):107-111. Eastern Mediterranean Health Journal 2009;15(1):19-24. Saudi Med J; 2008;29(3):466-8. 20 Ali M. Al- Amri, Abdulaziz A. Al- Coexisting malignant lymphoma of Saudi Med J 2007;28(3):463-

# Name of Investigator(s) Research Title Publisher and Date of Publication Quorain. the duodenum and adenocarcinoma 464. of the colon: Case Report. 21 Faris Q. Alenzi, Saleh M. Al- Ghamdi, Waleed G. Apoptosis role of FAS/FAS ligand system in regulation of myelopiosis. Yale Journal of Biology and Medicine 2005; 78(1):25-26. Tamimi,Abdulaziz M. Al- Sebiany, Iman M. El- Nashar, Iman El- Tounsi,Mohammad S. Bamaga, Maher M. Al- Enazi, Ali S. Al- Amri, Iman H. Al- Sheikh. 22 Ali M. Al- Amri. Prevention of breast cancer. J Family and Community Med 2005; 2(2):71-74. 23 Ali M. Al- Amri, Joseph M. Connors, Nicholas J.S. Voss, Randy D. Gascoyne, Alan A. Weiss. 24 Mohammad I. Quadri, Iman H. Al- Sheikh, Ahmad Al- Faraj, Hadi Al- Awami, Ali M. Al- Amri. 25 Ezzeldin M. Ibrahim, Fatima A. Al- Mulhim, Fahd Al- Muhanna, Ali M. Al- Amri. 26 Ezzeldin M. Ibrahim, Fatima A. Al- Mulhim, Ali M. Al- Amri,Fahad Al- Muhanna, Adnan A. zzat, Robert K. Stuart, Dahish Ajarim. Therapeutic outcome of gastric mucosa lymphoid tissue lymphoma: Review of 15 years experience. Splenic lymphoma with Villous Lymphocytes: Report of the three cases. Effect of G- M CSF on chemotherapy induced oral mucositis in non- neutropenic cancer patient. Breast cancer in the Eastern Province of Saudi Arabia. *Papers published after promotion to Associate Professor Refereed Scientific Research Papers Accepted for Publication The Canadian Journal of Gastroenterology 2001 (Abstract). Annals of Saudi Medicine 2000; 20(2):137-141. J Family and Community Med 1998; 5(1):37-43. Medical Oncology 1998; 15:241-247. # Name of Research Title Journal Acceptance Date Investigator(s) 1 Ali M. Al- Amri Clinical presentation and Journal of family and February 10 2015 causes of breast cancer diagnosis delay of patients with pregnancy associated breast cancer community medicine 2 Ali M. Al- Amri 'Surgical management of thyroid tumor; Single institutional experience of Eastern province of Saudi Arabia' Korean Journal of Clinical Oncology, MN: KJCO- 14-056 December 29, 2014 3 Ali M. Al- Amri Disclosure of cancer information among Saudi cancer patients Indian Journal of Cancer, MN: IJC_491_13 January 17, 2015 4 Ali M. Al- Amri Gestational trophoblastic Life Science Journal. July 20 2014

# Name of Investigator(s) Research Title Journal Acceptance Date neoplasia: clinical presentations and outcome of therapy MN: 20299_life_2030817. Completed Research Projects # Name of Investigator(s) (Supported by) 1 Ali M. Al- Amri Faris Al- Enezi (Non- budgeted) 2 Ali M. Al- Amri Abdullah Bamosa (KACST) 760x10 3 3 Dalal Al- Tamimi Philip S. Bernard Mohmed A. Shawarby Ali M. Al- Amri Maha Abdelhadi Research Title Cellular and molecular responses of Saudi CML patients to imatinib 10years experience Phase I clinical trial of thymoquinone in patients with advanced cancer resistant to standard therapy. Differential genetics and epigenetic insight backgrounding the immunoprofile of breast carcinoma: a predictive and prognostic biomarkers university hospital- based study Report Date December 2012 May 2009 Current Researches # Research Title Name of Investigator(s) 1 PIK3CA Mutation analysis in Head and Neck Squamous cell carcinoma Ali M. Al- Amri, Tariq Hashim, Cyril Cyrus Chittibabu Vatte 2 Intra- operative radiotherapy for breast cancer Maha Abdelhadi, Ali M. Al- Amri, Sami Al- Badawi. Contribution to Scientific Conferences and Symposia # Conference Title Place and Date of the Conference Extent of Contribution 1 Conference on clinical, pathologic & Al- Khobar 15-19,2015 Participant molecular medicine 2 13 th Saudi gastroenterology association Al- Khobar 25-27/11/ 2014 meeting &2 nd SALT meeting 3 Bioregional oncology meeting Dubai may 23-25/2014 Participant 4 Breast cancer: workshop and Al- Baha- July 3, 2013 Symposium meeting 5 ESMO Dammam May 2012 6 Breast Cancer Symposium for primary care physicians: Outreach Program Bisha February 27, 2013 7 Beyond convention: New perspectives In Dammam February 19, 2013 Participant

# Conference Title Place and Date of the Conference Extent of Contribution NSCLC 8 The power of multidisciplinary team Jeddah January 8, 2013 approach 9 Hepatology update on hepatitis b Al- Khobar May8-9, 2013 infection 10 The 4 th annual international breast Jeddah October3-4, 2012 cancer conference 11 The best of ASCO Dammam September12-13, 2012 Participant 12 23 rd scientific meeting in internal medicine on hematology and oncology Al- khobar November28-29, 2012 Participant, speaker and posters presenter 13 11 th update in internal medicine on Al- Khobar November23-24, 2011 Participant pulmonary and critical care 14 Hepatology update on hepatitis c Al- khobar May19, 2011 infection 15 Update in hematological malignancies Al- khobar November20-21, 2011 Participant 16 2 nd international breast health education Al- khobar March14-17, 2011 Participant program: A multidiscplinary approach to breast disease 17 European multidisciplinary cancer Stockholm September23-27, 2011 congress 18 Lung cancer symposium Al- khobar March21, 2010 19 10 th update in internal medicine Al- khobar December29-30, 2010 Participant 20 Breast cancer symposium Al- khobar October8, 2009 21 Update on breast cancer Saad specialist hospital May 26 2009 22 9 th update in internal medicine on Al- khobar December9-10, 2009 endocrine, diabetes and metabolic disorders 23 4 th Best of ASCO Lebanon- Beirut July10-11 2009 Participant 24 3 rd international scientific conference on Al- khobar April 29-30 2009 Genitourinary cancer 25 Tutorials on neuropathology Al- khobar March31- April 2, 2009 26 Two more minutes: Breast Cancer Maternity and Children s hospital, Symposium. Al- Ahsa, Saudi Arabia - 9 December 2008 27 Two more minutes Breast Cancer King Abdulla Hospital, Bisha, Saudi Symposium. Arabia, 21 August 2008 28 Update in osteoporosis course King Fahd Specialist Hospital, Dammam, Saudi Arabia 14 May 2008 29 8 th update in internal medicine on nephrology Al- khobar November 12-13 2008 30 7 th Update in Internal Medicine on Colorectal Diseases. King Fahd Hospital of the University (KFHU), Al- Khobar, Saudi Arabia. 21-22 November 2007. 31 2 nd International Scientific Conference( Gulf Meridien Hotel, Al- Khobar,

# Conference Title Place and Date of the Conference cancer forum 2007) Saudi Arabia 21-22 November 2007. 32 6 th Update in Internal Medicine on KFHU, Al- Khobar, Saudi Arabia Cardiology and Hypertension. 29-30 November 2006 33 International Day Awareness of Al- Khobar, Saudi Arabia Lymphoma. 15 September 2006. 34 Non- Hodgkin Lymphoma Symposium. Al- Khobar, Saudi Arabia 14 August 2006 35 AFME oncology/infectious Diseases Joint Cairo, Egypt Meeting 16-17 March 2006. 36 Nursing Oncology Course. Saudi Cancer Foundation, Al- Khobar, Saudi Arabia 15 March 2006. 37 Advances in Blood Transfusion. KFHU, Al- Khobar, Saudi Arabia 1 February 2006 38 5 th update in internal medicine on KFHU, Al- Khobar, Saudi Arabia - 7-8 Endocrinology and Rheumatology Dec 2005. 39 Non- Hodgkin Lymphoma Symposium. Al- Khobar, Saudi Arabia 19 May 2005. 40 Innovation in cancer: advance in therapy Rome, Italy with proteosome inhibition and 18 March 2005. supportive care. 41 International conference in clinical Oncology. Riyadh Armed Forces Hospital, Saudi Arabia 9-11 April 2005. Al- Khobar, Saudi Arabia 16-17 February 2005. Dubai, UAE 8-9 January 2005. KFHU, Al- Khobar, 15-16 December 2004. 42 First Scientific Conference on Gastrointestinal malignancies. 43 First Novartis Middle East and Africa Oncology Submit. 44 4 th Update in internal medicine on Pulmonary and Infectious Diseases. 45 Breast Cancer Workshop. Al- Khobar, Saudi Arabia December15 2004. 46 Local excision of rectal cancer. Al- Khobar, Saudi Arabia 6 October 2004. 47 Annual Oncology Update Seminar King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia 6 May 2004. 48 First Scientific Meeting on Hematological Malignancies. Al- Khobar, Saudi Arabia 14 April 2004. 49 Hematology and Oncology Meeting of Al- Khobar, Saudi Arabia Eastern Province. 22 March 2004. 50 Update of Breast Disease. KFHU, Al- Khobar, Saudi Arabia March3-4 2004. Extent of Contribution... 51 Second Roche Middle East Oncology Dubai, UAE

# Conference Title Place and Date of the Conference Extent of Contribution Conference. 14-15 January 2004. 52 Treatment of Metastatic Breast Cancer. Al- Khobar, Saudi Arabia Workshop for Primary Care Physician. January 2004. 53 Update in Internal Medicine on KFHU, Al- Khobar, Saudi Arabia Nephrology and Critical Care Medicine. 15-16 October 2003 54 Diabetes and Hypertension Symposium. KFHU, Al- Khobar 13-15 November 2001 55 3 day course on Diabetes and Al- khobar November 13-15 2001 hypertension 56 Hematology- oncology club symposium, Al- khobar October 29 2001 eastern province 57 Hematology and Oncology Club Al- khobar October 29 2001 58 7 th Annual Resident Research Day. 23 May 2001 Presented a poster. University of British Columbia, Canada. 59 7 th Annual Resident Research Day. 23 May 2001. University of British Columbia, Canada. 60 ASCO 2001 37 th Annual Meeting and 12-15 May 2001 Educational Symposium. San Francisco, CA, USA 61 Comprehensive Review of Clinical 10-11 May 2001, San Francisco, CA, Cancer Genetics. USA 62 Visiting Professor Program 8 March 2001 Vancouver Cancer Center, BC, Canada 63 Canadian Digestive Diseases Week. 21-28 February 2001 Presenter of a poster. Banff- Alberta, Canada 64 First Update in Internal Medicine 17-18 February 1999 KFHU, Al- Khobar 65 The 5 th Saudi Gastroenterology KFHU, Al- Khobar Association Meeting. 19-20 November 1997 66 Third Saudi Oncology Symposium 21-23 October 1996 Cancer Year of 1996 Riyadh 67 The Principle of Magnetic Resonance Imaging 26-27 October 1988, KFHU, Al- Khobar Membership of Scientific and Professional Societies and Organizations - International: Associate Member, American Society of Clinical Oncology (ASCO), USA, 2001 Representative in the Saudi commission for health specialty for oncology fellow program, health specialty for oncology fellow program, Riyadh, KSA, 2014 - National: Administrative member, Saud cancer Foundation, Al- Khobar, KSA, 2007 Reviewer, KACST, Riyadh, KSA, 2007

Teaching Activities Undergraduate # Course/Rotation Title 1 Introduction to Medicine Course 2 5th- year Clerkship Course in Medicine 3 6th Year Clerkship Course in Medicine No./Code (MDMD 451) (MDMD 501) (MDMD 601) 4 Nursing Course (MDMD 318) Extent of Contribution (no. of lectures/tutorials. Or labs, Clinics) A 6 credit- hour course that extends over a 6- week period and is offered to the 4th- year medical students for 4 rotations per year. The course emphasizes history- taking and physical examination. A 6- credit- hour course that is taught over a 6- week period and given to the 5th- year medical students for 6 rotations per year. The course objectives are to teach basic skills and the main subjects in Internal Medicine. A 10- credit- hour course in Medicine that lasts over 9 weeks and is offered to 6th year medical students for 4 rotations per year. The course concentrates on patients management, follow- up and principles of therapeutics. A 9- credit- hour course in Nursing; The Department of Internal Medicine gives lectures for this course including oncology lectures. Brief Description of Undergraduate Courses Taught: (Course Title Code: Description) 1 Breast cancer 2 Lymphoma Postgraduate # Course/Rotation Title 1 Data interpretation 2 Case study 3 Review No./Code Extent of Contribution (no. of lectures/tutorials. Or labs, Clinics) Brief Description of Postgraduate Courses Taught: (Course Title Code: Description) 1 Full participation in postgraduate training and evaluation of Internal Medicine interns, junior and senior residents, and demonstrators. It involves bedside clinical teaching, lectures, clinico- pathological meetings, tutorials, seminars and tumor board meeting (2001 - present). 2 Active participation in the Residency Training Program of the Saudi Board and Arab Board Internal Medicine. The program is a 4- year residency training and certified candidates are equated to those who hold other postgraduate degrees (2001 - present). 3 Active participation in the teaching of the MSc Occupational Medicine and Hygiene course (MDFM 8109) conducted by the Department of Family & Community Medicine, College of Medicine, University of Dammam. This is a 4- credit hour course and I was responsible for giving lectures on medical oncology. Course Coordination

# Course Title and Code Coordinatio n Co- coordination Undergra d. 1 MDMD601 Coordinator Undergrad uate 2 Master course in Coordinator aviation medicine Postgrad. From to Postgradua te 2013 2014 2013 2014 Administrative Responsibilities, Committee and Community Service (Beginning with the most recent) Administrative Responsibilities # From To Position Organization 1 Jan. 2014 Feb. 2015 Tumor board chairman KFHU 2 June. 2014 Aug.2014 6 th year exam. Coordinator KFHU 3 1995 Chief Resident in internal medicine KFHU Committee Membership # From To Position Organization 1 2014 2015 Clinical investigating committee KFHU 2 2007 2012 Blood transfusion and blood bank KFHU Volunteer Work # From To Type of Volunteer Organization 1 July 3 2013 July 4 2013 Breast cancer: workshop and Symposium meeting Saudi cancer foundation Al- Baha 2 February 27 2013 February 29 2013 Breast Cancer Symposium for primary care physicians: outreach Program Saudi cancer foundation Bishah 3 December 12 2012 December 13 2012 Two more minutes: Breast Cancer Symposium Saudi cancer foundation Al- Hafof Personal Key Competencies and Skills: (Computer, Information technology, technical, etc.) 1 Management and follow- up of patients with malignant diseases including chemotherapy, immunotherapy, hormonal therapy and bisphosphonate therapy. 2 Management and follow- up of patients with chronic leukemia and multiple myeloma 3 Excellent expertise in performing and interpreting liver biopsy specimens. 4 Excellent expertise in performing and interpreting bone marrow biopsy and aspiration specimens. 5 Excellent expertise in performing and interpreting pleural tab and pleural biopsy specimens and performing pleurodesis with chemotherapy. 6 Excellent expertise in performing and interpreting peritoneal tab and performing therapeutic peritoneal para- centasis of cancer patients. 7 Excellent expertise in performing and interpreting lumber puncture specimens and performing intra-

thecal chemotherapy. 8 Care of patients with advanced cancer who need best supportive care and palliative therapy. 9 Follow- up of patients with cancer on an outpatient as well as inpatient basis. 10 Management of patients with cancer and complications including febrile neutropenia, fungal infections and metabolic complications as hyponatremia. 11 Acute care including night calls for patients with tumor lysis syndrome. Last Update 12 February, 2015