Preliminary Agenda. 9:55-10:20 How to overcome TKI resistance? James Chih-Hsin Yang 10:20-10:40 Discussion All 10:40-10:55 Coffee break

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Preliminary Agenda November 7, 2018 14:00-17:00 Registration and check in Satellite Symposia with Dinner 17:00-18:30 Jiangsu Hengrui Medicine Co., Ltd 17:00-18:30 Satellite Symposia with Dinner 17:00-18:30 Satellite Symposia with Dinner 2 November 8, 2018 8:00-8:15 Opening Ceremony 8:15-10:40 8:15-8:40 8:40-9:05 9:05-9:30 9:30-9:55 Plenary Session Crystal Ballroom Past, Present and Future of Targeted Therapy in NSCLC Optimal sequence of EGFR TKI s in patients with EGFR mutations Optimal sequence of ALK TKI s in patients with ALK translocations Clinical application of ctdna in management of oncogenic driven lung cancer The reality of adjuvant/neoadjuvant targeted therapy for resectable lung cancer Speakers Yi-Long Wu, Jie He, Fred R. Hirsch Giorgio Scagliotti, Yi-Long Wu Tony Mok Ignatius Ou Shun Lu Yi-Long Wu 9:55-10:20 How to overcome TKI resistance? James Chih-Hsin Yang 10:20-10:40 Discussion All 10:40-10:55 Coffee break 10:55-11:30 Best abstracts selected from submissions Christian Manegold, Chun-Xue Bai 10:55-11:05 11:05-11:15 11:15-11:30 Discussant Keunchil Park All Satellite Symposiums with Lunch: 12:15-13:45 Shanghai Tongshu Biotechnology Co., Ltd 12:15-13:45 F. Hoffmann-La Roche Ltd. 12:15-13:45 Pfizer Investment Co., Ltd Crystal Ballroom 2

14:00-17:00 Parallel Session 1: Biomarker detection of lung cancer: new techniques and new opinions Zio-Qing Liu, Keunchil Park 14:00-14:25 How reliable is NGS-based genome profiling? Giorgio Scagliotti 14:25-14:50 What is a trustworthy biomarker? Christian Manegold 14:50-15:15 Standardization of molecular testing in China Xu-chao Zhang 15:15-15:40 What is beyond NGS? Shannon Chuai 16:40-17:00 Discussant Jie Hu 14:00-16:20 Parallel Session 2: Brain metastases and leptomeningeal metastasis Yun Fan, Bo Zhu Jian-Hua Chang, Robert Pirker 14:00-14:25 Is MRI a mandatory procedure for diagnosis of CNS Tan Shao Weng Daniel metastasis? 14:25-14:50 Optimal radiotherapy for CNS metastasis in patients with a driver oncogene You Lu 14:50-15:15 Can this drug penetrate the brain? Feng-Ming Kong 15:15-15:40 Diagnosis and management of leptomeningeal metastasis Jin-Ji Yang Tan Shao Weng, Daniel Di Zheng 16:40-17:00 Discussant Yong Song 1400-15:55 Parallel Session 3: Tobacco control, screening and staging in Asia Sumitra Thongprasert, Chang-li Wang 14:00-14:20 Tobacco control in China Xiu-Yi Zhi 14:20-14:40 Lung cancer screening in China Ning Wu 14:40-13:40 Lung cancer screening in Asia Sumitra Thongprasert 15:40-15:20 Lung cancer staging: change and challenge Hisao Asamura 15:20-15:40 Plasma-base molecular testing for early detection of lung cancer Eric Fung 15:40-15:55 Discussion All 15:55-16:10 Coffee break 2

16:10-17:00 Meet the JTO Editor-in-Chief Seiji Niho, Li Zhang 16:10-16:30 How to get your manuscript published in JTO Alex A. Adjei 16:30-16:54 How to write a manuscript Tony Mok 16:54-17:00 Discussion All 17:30-19:00 All Satellite Symposiums with Dinner: Chia Tai Tianqing Pharmaceutical Group Co., Ltd 17:30-19:00 Ascentage Pharma 17:30-19:00 Burning Rock Dx 20:00-22:00 President Dinner November 9, 2018 8:30-10:30 Plenary Session: Crystal Ballroom Immunotherapy for lung cancer Fred R. Hirsch, Shun Lu 8:30-8:55 Walking through the maze of first line immunotherapy for advanced NSCLC Fred R. Hirsch 8:55-9:20 Mechanisms and management of resistance to immune checkpoint therapy Navneet Singh 9:20-9:45 PDL1 expression versus TMB: Which should we use? Gen Lin 9:45-10:10 Development of immunotherapy in China Qing Zhou 10:10-10:30 Discussion All 10:30-10:50 Coffee break 10:50-11:30 Best abstracts selected from submissions James Chih-Hsin Yang, Mei-Lin Liao 10:50-11:00 11:00-11:10 11:10-11:30 Discussant Jiu-Wei Cui 12:15-13:45 All Satellite Symposiums with Lunch: prime Oncology 12:15-13:45 Bristol-Myers Squibb Company 12:15-13:45 Jiangsu Hengrui Medicine Co., Ltd Crystal Ballroom 2 12:15-13:45 Merck 3

14:00-16:20 Parallel Session 1: New strategy for neoadjuvant and adjuvant therapy Paul A. Bunn, Jr, Yong Song 14:00-14:25 New perspectives on neoadjuvant and adjuvant Paul A. Bunn, Jr therapy 14:25-14:50 New perspectives on neoadjuvant and adjuvant targeted therapy Wen-Zhao Zhong 14:50-15:15 New perspectives on neoadjuvant and adjuvant immunotherapy Robert Pirker 15:15-15:40 Predicting and monitoring biomarkers for early stage Seiji Niho NSCLC Navneet Singh, Ming-Fang Zhao 16:40-17:00 Discussant Bao-hui Han 14:00-16:00 14:00-14:25 Parallel Session 2: New strategy for locally advanced NSCLC NSCLC New wine in old bottle Should we apply the old data for stage III oncogenic driven lung cancer 4 Thanyanan Reungwetwattana Jie Wang Fan Yang 14:25-14:50 Immunotherapy for stage III NSCLC Thanyanan Reungwetwattana 14:50-15:15 New surgical techniques for stage III disease Norihiko Ikeda 15:15-15:40 Optimal RT for local advanced NSCLC Min Fan Norihiko Ikeda, Yi Hu 16:40-17:00 Discussant Jie Wang 14:00-16:00 Parallel Session 3: SCLC: developments and challenges Chong Kin Liam, Ying Cheng 14:00-14:25 Novel systemic therapy for SCLC Byoung Chul Cho 14:25-14:50 Genomic study for SCLC: Is this a waste of time? David Carbone 14:50-15:15 Is PCI still indicated Chong Kin Liam 15:15-15:40 Role of surgical resection and chemotherapy for T1-2N0 SCLC Zhen-Fa Zhang

16:20-1700 Best abstracts selected from submissions David Carbone, Ji-Feng Feng 16:40-17:00 Discussant Ying Cheng 17:30-19:00 All Satellite Symposiums with Dinners: 17:30-19:00 Berry Oncology Co., Ltd 17:30-19:00 Shanghai Tongshu Biotechnology Co., Ltd 20:00-22:00 Faculty Dinner November 10, 2018 Chinese Lung Cancer Association Annual Meeting 2018 Sessions will be in Chinese and English 8:30-10:35 Parallel Session 1: Oligomatastasis: what is the optimal treatment? Cai-Cun Zhou, Chun Chen, Qi-Bin Song 8:30-8:55 Oligomatastasis Medical Oncologist Perspective Cai-Cun Zhou 9:20-9:45 Oligomatastasis Surgical Oncologist Perspective Xue-Ning Yang 9:45-10:10 Oligomatastasis Radiation Oncologist Perspective Cong-Ying Xie 10:10-10:35 Discussion All 10:35-10:55 Coffee break 10:55-12:00 8:30-10:35 Satellite Symposium Parallel Session 2: Translational and clinical research in China 5 Cheng Huang, Qing-Hua Zhou, Yun-Chao Huang 8:30-8:55 Translational research in early stage NSCLC Huai-Quan Chen 8:55-9:20 Biomarker testing: where we are and where do we go from here? Bob T. Li 9:20-9:45 Translational research in late stage NSCLC Cheng-Ping Hu 9:45-10:10 Clinical Research in China Zhi-Yong Ma 10:10-10:35 Discussion All 10:35-10:55 Coffee break 10:55-12:00 8:30-10:35 Satellite Symposium Parallel Session 3: Diagnosis and treatment for small nodule in China Wei-Ming Mao, Qun Wang, Qiong Zhao 8:30-8:55 Early stage lung cancer: SBRT vs. surgery Zheng-Fei Zhu 8:55-9:20 New surgical technique for early stage lung cancer Gui-Bin Qiao

9:20-9:45 Genomic study for lung cancer in China Hong-Bing Shen 9:45-10:10 How to deal with multiple pulmonary nodules Wei-Min Li 10:10-10:35 Discussion All 10:35-10:55 Coffee break 10:55-12:00 Satellite Symposium Language: The official language of this conference on November 8 9 is in English. No simultaneous translation will be available. Official languages on November 10 th will be in English and Chinese. 6