US National Standards & Guidelines Capnography for Emergency Care

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US National Standards & Guidelines 2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Part 7.1: Adjuncts for Airway Control and Ventilation Even when the endotracheal tube is seen to pass through the vocal cords and tube position is verified by chest expansion and auscultation during positive-pressure ventilation, rescuers should obtain additional confirmation of placement using an end-tidal CO 2 or esophageal detection device (Class II a). There is a high risk of tube misplacement, displacement, or obstruction, especially when the patient is moved. Circulation 2005;112;51-57; originally published online Nov 28, 2005; ISSN: 1524-4539. Copyright 2005 American Heart Association. All rights reserved. Print ISSN: 0009-7322. To reduce the risk of unrecognized tube misplacement or displacement, providers should use a device such as an exhaled CO 2 detector or an esophageal detector device to confirm endotracheal tube placement in the field, in the transport vehicle, on arrival at the hospital, and after any subsequent movement of the patient. Part 7.4: Monitoring and Medications Although end-tidal CO 2 serves as an indicator of cardiac output produced by chest compressions and may indicate return of sponttaneous circulation (ROSC), there is little other technology available to provide real-time feedback on the effectiveness of CPR. End-tidal CO 2 monitoring is a safe and effective non-invasive indicator of cardiac output during CPR and may be an early indicator of ROSC in intubated patients. End-tidal CO 2 monitoring during cardiac arrest can be useful as a non-invasive indicator of cardiac output generated during CPR (Class II a). In the patient with ROSC, continuous or intermittent monitoring of end-tidal etco 2 provides assurance that the endotracheal tube is maintained in the trachea. End-tidal CO 2 can guide ventilation, especially when correlated with the PaCO 2 from an arterial blood gas measurement. Circulation 2005;112;78-83; originally published online Nov 28, 2005; Copyright 2005 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Pediatric Exhaled CO 2 detection is the recommended primary technique to confirm correct endotracheal tube placement when a prompt increase in heart rate does not occur after intubation. Monitor exhaled CO 2, especially during transport and diagnostic procedures. Insert a gastric tube to relieve and help prevent gastric inflation. Neonatal Exhaled CO 2 detection is effective for confirmation of endotracheal tube placement in infants, including very low birth weight infants (LOE 5). Except for intubation to remove meconium, exhaled CO 2 detection is the recommended method of confirmation. (Class II a) 2005; American Heart Association (AHA) Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC) of Pediatric and Neonatal Patients. American Heart Association Pediatrics 2006; 117; 989-1038.

US National Standards & Guidelines Emergency Department 2005 Emergency Nurses Association (ENA) Patients undergoing sedation and analgesia require frequent assessments of their vital signs such as heart rate, blood pressure, respiratory rate, and pulse oximetry; cardiopulmonary status including cardiac monitoring, breath sounds, skin color, oxygen saturation, and exhaled carbon dioxide. Emergency Nurses Association Position Statement Procedural Sedation and Analgesia in the Emergency Department. Revised and Approved by the ENA Board of Directors: July, 2005. ACEP (American College of Emergency Physicians) ACEP Policy Statement Revised and approved by the ACEP Board of Directors April 2009. End-tidal carbon dioxide detection is the most accurate technology to evaluate endotracheal tube position in patients who have adequate tissue perfusion. Properly placed endotracheal tubes may become displaced due to movement of patients and/or equipment. Continuous assessment of correct endotracheal tube placement with continuous end-tidal carbon dioxide monitoring is ideal. 2008 American College of Emergency Physicians (ACEP) Among pre-hospital providers, reports of missed intubations range between 0-5%, although a recent study demonstrated a substantially higher rate (25%) of misplaced endotracheal tubes when patients intubated in the field were re-evaluated upon presentation to the emergency department. Pulse oximetry alone is inadequate because desaturation as a marker for a misplaced endotracheal tube can be a late finding depending on the amount of pre-oxygenation the patient has undergone. End-tidal CO 2 detection approaches 100% sensitivity and specificity in the patient with spontaneous circulation. Several professional organizations including the American Society of Anesthesiologists, the National Association of EMS Physicians, and the American Heart Association recommend utilizing secondary tube confirmation techniques such as end-tidal CO 2 measurements. American College of Emergency Physicians; Practice Resources. Policy Resource and Education Paper; an explication of the Policy Statement: Verification on Endotracheal Tube Placement http://www3.acep.org/practres.aspx?id=29940 ACEP (American College of Emergency Physicians) Godwin SA, Caro DA, Wolf SJ, Jagoda AS, Charles R, Marett BE, Moore J, American College of Emergency Physicians. Clinical policy: procedural sedation and analgesia in the emergency department. Ann Emerg Med 2005 Feb;45(2):177-96. Capnometry is a technique used to monitor etco 2 and, therefore, may detect early cases of inadequate ventilation before oxygen desaturation takes place. An increase in etco 2 might be the only clue to hypoventilation and potential respiratory compromise. The authors conclude that in the presence of etco 2 monitoring, these identifiers may allow more rapid identification of hypoventilation than pulse oximetry alone. In the study, pulse oximetry would have identified only 11 of the 33 patients meeting the predetermined definitions for respiratory depression of an oxygen saturation less than 90%, etco 2 of greater than 50 mm Hg, or an absent waveform.interventions and practices considered: Pulse oximetry and capnometry if indicated How should respiratory status be assessed? Consider capnometry to provide additional information regarding early identification of hypoventilation.

US National Standards & Guidelines 2005 American College of Emergency Physicians (ACEP) Standard physical examination methods, such as auscultation of lungs and epigastrium, visualization of chest movement and fogging in the tube, are not sufficiently reliable to exclude esophageal intubation in all situations. End-tidal CO 2 detection, either qualitative, quantitative or continuous, is the most accurate and easily available method to monitor correct endotracheal tube position in patients who have adequate tissue perfusion. Pulse oximetry and esophageal detector devices are not as reliable as end-tidal CO 2 determinations in patients who have adequate tissue perfusion. For patients in cardiac arrest and for those with markedly decreased perfusion, direct visualization or other methods of confirmation should be done when end-tidal CO 2 does not confirm tracheal intubation. American College of Emergency Physicians; Verification of Endotracheal Tube Placement; August, 2005. Emergency Medical Services (EMS) 2007 National Association of EMS Physicians In the patient with a perfusing rhythm, end-tidal CO 2 detection is the best method for verification. In the absence of a perfusing rhythm, capnography may be extremely helpful, and may be superior to colorimetric methods. The esophageal detector device may be unreliable in certain clinical setting and should be used as an adjunct to other confirmatory methods. Verification of Endotracheal Tube Placement Following Intubation. Robert E. O Connor, MD, MPH, Robert A. Swor, DO, for the National Association of EMS Physicians Standards and Clinical Practice Committee; Approved 2/99; Reaffirmed 2/07. National Highway Traffic Safety Administration National Emergency Medical Services Education Standards, Jan 2009 Safely and effectively perform all psychomotor skills within the National EMS Scope of Practice Model and state Scope of Practice at this level. Airway and Breathing: etco 2 monitoring Guidelines for emergency tracheal intubation immediately following traumatic injury The intubation protocols and study conclusions indicate that carbon dioxide monitoring should be performed during emergency tracheal intubation. Carbon dioxide monitoring is recommended for emergency tracheal intubation in trauma patients by multiple professional organizations. These groups include the National Association of Emergency Medical Technicians, the American College of Emergency Physicians, the National Association of EMS Physicians, the Italian Societies of Neurosurgery and Anesthesia and Intensive Care, the American College of Surgeons, Committee on Trauma, the American College of Emergency Physicians, and the National Association of EMS Physicians. The American College of Surgeons Committee on Trauma requires a capnography device for Level I-IV trauma center verification. EAST Practice Management Guidelines; 2002, Eastern Association for the Surgery of Trauma; http://www.east.org/tpg/intubation.pdf

US National Standards & Guidelines FDNY (Fire Department City of New York) New York City Office of Medical Afairs; Policy and Procedure for performing continuous end tidal waveform capnography According to the New York State Department of Health, the new standard of care for all patients intubated by paramedics in the prehospital setting is monitoring with continuous end-tidal waveform capnography to confirm advanced airway device placement. Patients with pre-existing advanced airways (e.g., advanced nursing facilities patients) requiring mechanical ventilation must have continuous EtCO 2 waveform capnography monitoring during treatment / transport. North Carolina College of Emergency Physicians 2009 NCCEP Standards for EMS Equipent Monitoring and Defibrillation: Capnography (etco 2 ) monitoring, continuous. Baseline equipment required in all systems (including Specialty Care Transport Programs), with EMS personnel credentialed at the specified level--emt, EMT-I, EMT-P. It is not required but highly recommended that all EMS Systems at all levels work to have waveform Capnography capability at the scene of every emergency event. Orange County EMS System Protocol Airway Management - Adult Following intubation with ETT, LMA, or Combitube, confirm proper placement: Record end-tidal CO 2 and monitor continuously. Patients should not have a step down in the method used to record end-tidal CO 2. For instance, if the patient is initially monitored with a capnographic waveform (e.g. LifePak 12), this should not be switched to colorimetric device for monitoring end-tidal CO 2. The Ohio Board of Emergency Medical Services The service has continuous end- tidal CO 2 monitoring capabilities or waveform capnography. Ohio EMS Board Statement Regarding Rapid Sequence Induction (RSI) for endotracheal intubation, October, 2008. The Regional Emergency Medical Services Council of New York City The Regional Emergency Medical Advisory Committee (REMAC) of New York City Prehospital Treatment Protocols; Revision, November, 2009 All patients with endotracheal tube placement require continuous end-tidal waveform capnography to confirm advanced airway device placement. When available, the use of waveform capnography should accompany the use of alternative advanced airway devices (i.e. Combitube, King Airway, LMA) Westchester Regional EMS Council (New York) All patients who require endotracheal intubation MUST have WFC (waveform capnography) in place at time of intubation and continuously thereafter, effective January 1, 2009. The WFC device must be able to print and/or store data either at the hospital, at the end of the EMS call, or later, for QA/QI purposes. Update to Advisory Statement 02-01: Secondary confirmation of ETT. October 2, 2008 www.wremsco.org State of New York; State Emergency Medical Advisory Committee The SEMAC has endorsed and recognized as a standard of care that all out of hospital adult and pediatric patients who require ETT intubation must have waveform capnography in place at the time of intubation and throughout the entire time the ETT is in place. This advisory becomes effective state-wide on June 1, 2009. Advisory 08-01; Confirmation of ETT Required Capnography; 1/2/09

US State standards & guidelines = Protocols set at Regional/Local Level or No state protocols found Q = etco2 Detector/Capnometry M=Mandate R=Recommend S=Standard Y=Mention W=Waveform Capnography Regional Councils No Protocol Found ETT Placement Verification/Post intubation monitoring Pediatric ETT placement Verification All Other Advanced Airways, LMA, EOA, King, & Blind Insertion Rapid Sequence Intubation (RSI- DAI) Medications )Not RSI( Head Trauma Altered Mental Status Oxygen, Hypoxic COPD/Bronchospastic Disease CPAP Mechanical Ventilation Hypoventilation ROSC IV Lidocaine, Nitroglycerine Shock Chest pain/chf Hypothermia Induced Hypothermia Toxicology Required Equipment Required Skill Alabama Q WY WY mw Alaska Arizona Arkansas Q California Colorado QWS Connecticut wr Deleware District of Columbia Florida Georgia QS Hawaii

US State standards & guidelines = Protocols set at Regional/Local Level or No state protocols found Q = etco2 Detector/Capnometry M=Mandate R=Recommend S=Standard Y=Mention W=Waveform Capnography Regional Councils No Protocol Found ETT Placement Verification/Post intubation monitoring Pediatric ETT placement Verification All Other Advanced Airways, LMA, EOA, King, & Blind Insertion Rapid Sequence Intubation (RSI- DAI) Medications )Not RSI( Head Trauma Altered Mental Status Oxygen, Hypoxic COPD/Bronchospasttic Disease CPAP Mechanical Ventilation Hypoventilation ROSC IV Lidocaine, Nitroglycerine Shock Chest pain/chf Hypothermia Induced Hypothermia Toxicology Required Equipment Required Skill Idaho Illinois Indiana Iowa Q Q Kansas Kentucky Lousiana Maine Maryland Massachusetts WR Michigan Minnesota

US State standards & guidelines = Protocols set at Regional/Local Level or No state protocols found Q = etco2 Detector/Capnometry M=Mandate R=Recommend S=Standard Y=Mention W=Waveform Capnography Regional Councils No Protocol Found ETT Placement Verification/Post intubation monitoring Pediatric ETT placement Verification All Other Advanced Airways, LMA, EOA, King, & Blind Insertion Rapid Sequence Intubation (RSI- DAI) Medications )Not RSI( Head Trauma Altered Mental Status Oxygen, Hypoxic COPD/Bronchospasttic Disease CPAP Mechanical Ventilation Hypoventilation ROSC IV Lidocaine, Nitroglycerine Shock Chest pain /CHF Hypothermia Induced Hypothermia Toxicology Required Equipment Required Skill Mississippi QS Missouri Q Montana Nevada Nebraska New Hampshire New Jersey New Mexico new york QUM North Carolina North Dakota

US State standards & guidelines Regional Councils No Protocol Found ETT Placement Verification/Post intubation monitoring Pediatric ETT placement Verification All Other Advanced Airways, LMA, EOA, King, & Blind Insertion Rapid Sequence Intubation (RSI- DAI) Medications )Not RSI( Head Trauma Altered Mental Status Oxygen, Hypoxic COPD/Bronchospasttic Disease CPAP Mechanical Ventilation Hypoventilation ROSC IV Lidocaine, Nitroglycerine Shock Chest pain/chf Hypothermia Induced Hypothermia Toxicology Required Equipment Required Skill Ohio Oklahoma Oregon x Pennsylvania Q Q Q Q Rhode Island South Carolina* South Dakota x Tennessee Texas Utah x * Medical Control Committee Minutes, August 30, 2007. A motion was made by Dr. Sorell that real time, continuous digital capnography and oxygen saturation should be mandatory for all airway interventions where intubations are used. Dr. Norcross seconded the motion. It was determined by the Committee that January 1, 2010 would be the implementation date. However, the service may begin as soon as they have the ability to do so.

US State standards & guidelines = Protocols set at Regional/Local Level or No state protocols found Q = etco2 Detector/Capnometry M=Mandate R=Recommend S=Standard Y=Mention W=Waveform Capnography Vermont Virginia Washington West Virginia Wisconsin Wyoming Regional Councils No Protocol Found ETT Placement Verification/Post intubation monitoring Pediatric ETT placement Verification All Other Advanced Airways, LMA, EOA, King, & Blind Insertion Rapid Sequence Intubation (RSI- DAI) Medications )Not RSI( Head Trauma Altered Mental Status Oxygen, Hypoxic COPD/Bronchospasttic Disease CPAP Mechanical Ventilation Hypoventilation ROSC IV Lidocaine, Nitroglycerine Shock Chest pain/chf Hypothermia Induced Hypothermia Toxicology Required Equipment Required Skill WY Q Q Q QY QY x

International guidelines & standards Country / Region Environment Guidelines Issue European Union EMS/ED ERC Guidelines 2005 Correct tube placement Clinical signs of correct tube placement (condensation in the tube, chest rise, breath sounds on auscultation of lungs, and inability to hear gas entering the stomach) are not completely reliable. Secondary confirmation of tracheal tube placement by an exhaled carbon dioxide or oesophageal detection device should reduce the risk of unrecognized esophageal intubation. European Union EMS/ED Pediatric ERC Guidelines 2005 Correct tube placement Pediatric life support The anatomy of a child s airway differs significantly from that of an adult; hence, intubation of a child requires special training and experience. Check that tracheal tube placement is correct by clinical examination and end-tidal capnography. The tracheal tube must be secured, and monitoring of the vital signs is essential. European Union EMS/ED ERC Guidelines 2005 Cardiac output Indicator End-tidal CO 2 monitoring is a safe and effective non-invasive indicator of cardiac output during CPR and may be an early indicator of ROSC in intubated patients. European Union EMS/Transport European Committee on Standardization Requirements for equipping of road ambulances used for the transport and care of patients. CEN 1789:2007 is the European Union standard for ambulances and medical transportation vehicles. This European standard specifies requirements for the design, testing, performance and equipping of road ambulances used for the transport and care of patients. UK EMS The Joint Royal Colleges Ambulance Liaison Committee Measurement of exhaled CO 2 should be used if possible to ensure correct tracheal tube placement if the child has been intubated. UK Ambulance Service Clinical Practice Guidelines (2006) Paediatric ALS Guidelines - Correct ET tube placement

International Standards & Guidelines Country / Region Environment Guidelines Issue UK, Ireland ICU/ED/EMS The Association of Anaesthetists of Great Britain and Ireland, May 2006 transfer of patients with brain injury Monitoring should include:.capnography Essential equipment to go with the patient in the ambulance: Portable battery powered multifunction monitor to include: capnography.. UK, Ireland ICU/ED/EMS The Association of Anaesthetists of Great Britain and Ireland, 2007 Guidelines for the management of a Malignant Hyperthermia Crisis. Diagnosis - consider MH if: 1. Unexplained, unexpected increase in end-tidal CO2 together with 2. Unexplained, unexpected tachycardia together with 3. Unexplained, unexpected increase in oxygen consumption monitor: ECG, SpO 2, end-tidal CO 2,, invasive arterial BP, CVP, core and peripheral temperature, urine output and ph Ireland ED The Irish Association for Emergency Medicine Standards for Emergency Department Design and Specification for Ireland 2007 Each Resuscitation Area patient space must: Have full individual physiological monitoring including ECG, NIBP, Oxygen saturation, core temperature, invasive monitoring, end-tidal CO 2 monitoring etc. Ireland ED The Irish Association for Emergency Medicine Guidelines for Equipment and Supplies for Paediatric Patients Adapted from Care of Children in the Emergency Department: Guidelines for Preparedness. American Academy of Pediatrics Monitoring equipment: End- tidal CO 2, monitor Method to monitor endotracheal tube and placement May be satisfied by a disposable CO 2 detector of appropriate size for infants and children. For children 5 years or older who are >20kg in body weight, an oesophageal detection bulb or syringe may be used in addition.

International Standards & Guidelines Country / Region Environment Guidelines Issue Australia EMS/ED Australian resuscitation council Guideline 11.7 Feb 2006 Prehospital airway management. Capnography or CO 2 detection after initial intubation is recommended to confirm tracheal placement with realisation that CO 2 excertion cannot occur without pulmonary blood flow. Lack of CO 2 detection implies non-tracheal intubation or lack of pulmonary blood flow or both. Monitoring: End-tidal CO 2 (Classe A): Studies of CO 2 detection during a perfusing cardiac rhythm and during resuscitation at cardiac arrest have a high level of sensitivity and specificity for tube position. End-tidal CO 2 (PetCO 2 capnography) or other modes of CO 2 detection are recommended to confirm every tracheal intubation and during mechanical ventilation to guard against inadvertent eosopheal intubation and inadvertent extubation, particulary when the intubated patient undergoes transport to within or between hospitals... Scandinavia EMS the Scandinavian Society of Anaesthesiologists Prehospital airway management. End-tidal carbon dioxide (EtCO 2 ) monitoring is a standard, obligatory adjunct in the modern anaesthetic and critical care setting. EtCO 2 monitoring provides non-invasive information regarding CO 2 production, pulmonary perfusion, alveolar ventilation and respiratory patterns. The absence of EtCO 2 indicates either a misplaced or dislodged ET (oesophageal intubation or accidental extubation) or absent/decreased CO 2 production as in cardiac arrest. EtCO 2 can be detected or measured by the following methods colometric, capnometry and capnography. MM0450A