Comparison of organ doses estimations in radiology with PCXMC application based on MIRD phantoms and CALDose-X application based on voxel phantoms

Similar documents
FAX, A FEMALE ADULT VOXEL PHANTOM FOR RADIATION PROTECTION DOSIMETRY

A Real-Time Monte Carlo System for Internal Dose Evaluation Using an Anthropomorphic Phantom with Different Shapes of Tumors Inserted

Measurement of organ dose in abdomen-pelvis CT exam as a function of ma, KV and scanner type by Monte Carlo method

Assessment of effective dose in paediatric CT examinations

Radiation Dosimetry for CT Protocols

Assessment of radiation risk to pediatric patients undergoing conventional X-ray examinations

CALDose_X a software tool for absorbed dose calculations in diagnostic radiology

CT Radiation Dosimetry Study Using Monte Carlo Simulation and. Computational Anthropomorphic Phantoms

CT Dose Estimation. John M. Boone, Ph.D., FAAPM, FSBI, FACR Professor and Vice Chair of Radiology. University of California Davis Medical Center

Machine Learning Powered Automatic Organ Classification for Patient Specific Organ Dose Estimation

Introduction and Background

MT09 - Normal Human Tissue Microarray, FDA

Use Of MCNP With Voxel-Based Image Data For Internal Dosimetry Applications

Cone Beam CT Protocol Optimisation for Prostate Imaging with the Varian Radiotherapy OBI imaging system. Dr Craig Moore & Dr Tim Wood

Calculation of Normalised Organ and Effective Doses to Adult Reference Computational Phantoms from Contemporary Computed Tomography Scanners

Posture-specific phantoms representing female and male adults in Monte Carlo-based simulations for radiological protection

IMPC phenotyping SOPs in JMC

MAX06 and FAX06: Update of two adult human phantoms for radiation protection dosimetry

Determination of the conversion factor for the estimation of effective dose in lungs, urography and cardiac procedures

Skyscan 1076 in vivo scanning: X-ray dosimetry

Impact of ICRP-89 Based Models on Dose Estimates for Radiopharmaceuticals and CT Exams

Whole-body biodistribution and radiation dosimetry estimates for the β-amyloid radioligand [ 11 C]MeS-IMPY in non-human primates

Estimating Testicular Cancer specific Mortality by Using the Surveillance Epidemiology and End Results Registry

Dosimetry of recently introduced CBCT Units for Oral and Maxillofacial Radiology

Impact of ICRP-89 Based Models on Dose Estimates for Radiopharmaceuticals and CT Exams. Stabin MG, Kost SD, Clark JH, Pickens DR, Price RR, Carver DE

JHM-IRB Guidelines for Radiation Statements

An Assessment of Organ and Effective Dose of Patients who Undertake CT Examinations in two Teaching Hospitals of Mashhad&Isfahan

[Setawati et. al., Vol.4 (Iss10): October, 2017] ISSN: DOI: /zenodo

Out-of-field organ doses from therapeutic irradiation during childhood: is there an excess risk for second cancer induction?

Austin Radiological Association Ga-68 NETSPOT (Ga-68 dotatate)

MONTE CARLO SIMULATIONS FOR HOMELAND SECURITY USING ANTHROPOMORPHIC PHANTOMS. A Thesis Presented to The Academic Faculty.

Estimation of Effective Doses for Radiation Cancer Risks on ISS, Lunar and Mars Missions with Space Radiation Measurements

ICRP Recommendations Evolution or Revolution? John R Cooper Main Commission

Equivalent dose to organs and tissues in Hysterosalpingography calculated with the FAX (Female Adult voxel) phantom

ICRP Perspective on Internal Dosimetry OIR and Radiopharmaceuticals

Estimated Radiation Dose Associated With Low-Dose Chest CT of Average-Size Participants in the National Lung Screening Trial

A REVISED MODEL FOR DOSIMETRY IN THE HUMAN SMALL INTESTINE. Final Progress Report

Measurement of Kidneys Dose in Three Hospitals during Chest and Abdomen Radiographic Examinations

A more accurate method to estimate patient dose during body CT examinations with tube current modulation

Amira K. Brown, Ph.D. Molecular Imaging Branch, NIMH Bldg. 1 Rm. B3-10

Use of Monte Carlo Simulation Software for Calculating Effective dose in Cone Beam Computed Tomography

Radiological Protection Countermeasures after TEPCO Fukushima NPP Accident -Who should play the role of risk communication-

RADIOLOGIC TECHNOLOGY (526)

A Probabilistic Approach for the Assessment of Internal Dose to Chronic Lymphocytic Leukemia Precursor Cells

Multi-normal human tissues, FDA, 96 samples, 35 organs/sites from three individuals (1.5mm)

Evaluation of the doses delivered to premature babies in the Belgian Neonatal Intensive Care Units

Radiation exposure of the Yazd population from medical conventional X-ray examinations

Medical Physics and Informatics Original Research

Comparison of absorbed fraction of Gamma and Beta rays of I-124 and I-131radio-isotopes in thyroid gland with Monte Carlo Simulation

A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs

The impact of SID and collimation on backscatter in radiography

Austin Radiological Association Nuclear Medicine Procedure PET SODIUM FLUORIDE BONE SCAN (F-18 NaF)

Colour on-line figures None Colour print figures None

OVARIES URETER FALLOPIAN TUBES BLADDER UROGENITAL OPENINGS (BOTH SEXES) PENIS VAGINA UTERUS

2005 RECOMMENDATIONS OF ICRP

Radiation Safety Information for Students in Courses given by the Nuclear Physics Group at KTH, Stockholm, Sweden

ICRP = International Commission on. recommendations and guidance on. Functioning since 1928.

PHY138Y Nuclear and Radiation

Prof. Dr. Doğan BOR Ankara University Institute of Nuclear Science

Overview of Anatomy & Physiology

Epidemiology in Texas 2006 Annual Report. Cancer

Doses Received by Patients during Thorax X-Ray Examinations

Attention. Therefore, all the data and statements made in this presentation are preliminary and might change in the future.

Recent Progress in Radiation Dosimetry for Epidemiology and Radiological Protection. John Harrison ICRP Committee 2

Patti Edwards, Senior Radiographer, West Herts Hospitals, UK. February Radiation Safety

CALDose_X online: Web-based, real time Monte Carlo calculations for patient dosimetry in X-ray diagnosis

Radiation Protection Program Update: The Details. July 2010

Non-target dose from radiotherapy: Magnitude, Evaluation, and Impact. Stephen F. Kry, Ph.D., D.ABR.

Estimating Patient Radiation Dose from Computed Tomography

Patient effective dose evaluation for chest X-ray examination in three digital radiography centers

The Management of Imaging Procedure Dose Nuclear Medicine Dose Indices

Accuracy Requirements and Uncertainty Considerations in Radiation Therapy

Cancer survival in Shanghai, China,

Organ Dose Variability with Gender, Age and BMI

Calculation methods in Hermes Medical Solutions dosimetry software

Dosimetric Consideration in Diagnostic Radiology

Effective Dose Conversion Coefficients for X-ray Radiographs of the Chest and the Abdomen

Online VM Study Group. RoadMap

Nervous System. Skeletal System. Muscular System. Reproductive System. Circulatory System. Endocrine System. Respiratory System. Integumentary System

Review of the Radiobiological Principles of Radiation Protection

Study of the Influence of Radionuclide Biokinetic Distribution in Human Body on the Efficiency Response of Lung Counters

Pricelist Human Models HUMAN MODELS FUNCTIONAL MODELS ACUPUNCTURE MODELS ANATOMY MODELS DENTAL - MODELS

Welcome to ANAT 10A! What is Anatomy? Different levels of Anatomy The Language of Anatomy Pearson Education, Inc.

7/4/2018. Key Objectives. A and P 2401 Lecture 2 TWO MECHANISMS USED TO MAINTAIN HOMEOSTASIS. Negative Feedback Examples. Review of Homeostasis

Radiology CPT. CPT copyright 2011 American Medical Association. All rights reserved.

3 rd International Symposium on the System of Radiological Protection Seoul, October John Harrison

HEALTHFIRST 2011 RADIOLOGY PROGRAM CODE LIST

Application of 3D Printing to Molecular Radiotherapy Phantoms. Nick Calvert Nuclear Medicine Group The Christie NHS Foundation Trust, Manchester

State of the art and future development for standardized estimation of organ doses in CT

Body Systems Notes. Nervous, Integumentary, Immune/Lymphatic, Circulatory, Skeletal, Respiratory, Digestive, Excretory, Endocrine, Reproductive

HIP RADIOLOGY PROGRAM CODE LISTS

DEPARTMENT OF ANATOMY FIRST M.B.B.S. (BATCH ) TEACHING PROGRAMME (January March 2018) 1.00pm 2.00 pm (Demo) Batch A Dr. Uma Batch B Dr.

ICRP Symposium on the International System of Radiological Protection

Cancer survival in Seoul, Republic of Korea,

Longevitology Toronto Canada Questions. A: Two compulsory questions: B: 102 Questions

Lu-DOTATATE PRRT dosimetry:

Introduction. Measurement of Secondary Radiation for Electron and Proton Accelerators. Introduction - Photons. Introduction - Neutrons.

Radiation Doses in Radiology: Influence of Standards and Regulations

A. DeWerd. Michael Kissick. Larry. Editors. The Phantoms of Medical. and Health Physics. Devices for Research and Development.

Transcription:

Comparison of organ doses estimations in radiology with PCXMC application based on MIRD phantoms and CALDose-X application based on voxel phantoms G. Gialousis 1, Z. Pappouli 2, A. Dimitriadis 2, E. Karavassilis 2, E. Georgiou 2 and E. Yakoumakis 2 1 IASO Hospital, Medical Physics Department, 37-39 Kifissias Str., Maroussi 15123, Athens, Greece 2 Medical Physics Department, Medical School, University of Athens, Greece * Presenting author : gialousis@med.uoa.gr

Purpose The estimation of organ doses in Radiology is a complicated procedure. The difficulty initially depends on the recording of the geometrical parameters of the examinations, such as X-ray field limits on the patient and focus surface distance. Also, challenging step is the estimation of organ doses which depends on the X-ray spectrum and the absorption of photons within the body. The purpose of current study is to estimate doses with software packages PCXMC and CALDose-X and to examine differences.

Monte Carlo simulation by PCXMC [1] simulates body with hermaphrodite MIRD mathematical phantoms. MIRD phantoms have been widely used for many years in numerous studies. CALDose-X [2] application uses 2 tomographic phantoms, the male MAX06 and female FAX06 [3], consisted of 1.2mm cubic voxels and anatomical data in accordance to ICRU 70 and 89. These phantoms are used in standard predefined examinations projections and geometries. Field sizes represent commercial x-ray film formats. Both applications give the abillity to create x-ray energy spectrum and further to take into account the x-ray output of the radiological unit. Adult s radiological examinations were simulated, with the x-ray geometry and x-ray output settings sellected by CALDose-X. Cases examined at chest, abdomen, pelvis and lumbar spine. 1. M. Tapiovaara et al. PCXMC: A PC-based Monte Carlo program for calculating patient doses in medical x-ray examinations, report STUK-A139, (Helsinki: Finnish Centre for Radiation and Nuclear Safety) 1997. 2. R. Kramer et al. CALDose-X - a software tool for the assessment of organ and tissue absorbed dose, effective dose and cancer risks in diagnostic radiology. Phys. Med. Biol. 53, 6437-6459, 2008. 3. R. Kramer et al. MAX06 and FAX06: update of two adult human phantoms for radiation protection dosimetry. Phys.Med Biol. 51 3331-3346, 2006.

Graphical interface of PCXMC

Graphical interface of CALDOSE-X

Chest RLAT PCXMC CALDose-X male CALDose-X female CALDose-X average male- female PCXMC vs average CALDose-X organ (msv/mgy) (msv/mgy) (msv/mgy) (msv/mgy) Ovaries 3 Active bone marrow 0.085 0.17 0.26 0.215-153% Skeleton 0.162 surface bone cells 0.66 1.12 0.89 Lungs 0.32 0.15 0.28 0.215 33% Lower large intestine - colon 0.004 0.05 0.1 0.075-1775% Stomach 0.036 0.08 0.11 0.095-164% Liver 0.571 0.41 0.59 0.5 12% Thyroid 8 0.03-11% Oesophagus 0.125 0.06 0.09 0.075 40% Breasts 0.372 0.59 0.35 0.47-26% Urinary bladder 0.003 Skin 0.146 1.65 1.52 1.585-986% Adrenals 0.14 0.11 0.16 5 4% Kidneys 0.178 0.08 0.18 27% Pancreas 0.085 0.1 0.15 0.125-47% Small intestine 0.063 0.03 0.07 0.05 21% Upper large intestine -colon 0.106 0.05 0.1 0.075 29% Spleen 0.04 0.03-50% Thymus 0.141 0.08 0.23 0.155-10% Total Body 0.14 0.16 0.15-15%

Abdomen PA PCXMC CALDose-X male CALDose-X female CALDose-X average male- female PCXMC vs average CALDose-X organ Ovaries 0.354 0.38 Testes 0.164 0.04 Active bone marrow 0.656 0.12 0.18 0.15 77% Skeleton 0.155 surface bone cells 0.77 0.8 0.785 Lungs 3 57% Lower large intestine - colon 0.354 0.59 0.56 0.575-62% Stomach 0.594 0.44 0.42 0.43 28% Liver 0.386 0.19 0.23 0.21 46% Oesophagus 1 9% Breasts 0.008-25% Urinary bladder 0.686 0.48 0.43 0.455 34% Skin 0.174 1.45 1.41 1.43-722% Adrenals 0.083 0.14 0.12-57% Kidneys 0.095 0.22 0.18 0.2-111% Pancreas 0.248 0.36 0.32 0.34-37% Small intestine 0.415 0.64 0.59 0.615-48% Spleen 0.153 0.31 0.29 0.3-96% Total Body 0.18 0.19 0.22 0.21-14.5

Pelvis PA PCXMC CALDose-X male CALDose-X female CALDose-X average male- female PCXMC vs average CALDose-X organ Ovaries 0.34 0.42 0.21 38% Testes 1.157 0.855 0.4275 63% Active bone marrow 0.047 0.17 0.31 0.24-411% Skeleton 0.095 surface bone cells 0.87 0.95 0.91 Lower large intestine - colon 0.351 0.19 0.35 0.27 23% Stomach 0.046 5 67% Liver 8 0.005 82% Urinary bladder 0.727 0.5 0.55 0.525 28% Skin 0.164 1.46 1.53 1.495-812% Adrenals 0.005 50% Kidneys 6 0.03 0.07 0.05-92% Pancreas 4 5-7% Small intestine 0.342 0.35 0.44 0.395-15% Upper large intestine -colon 0.426 0.19 0.35 0.27 37% Spleen 2 5-25% Uterus 0.426 0.35 0.175 59% Gall bladder 0.082 prostate 0.41 0.205 Total Body 0.148 12%

Dose values in organs out of x-ray limits which were almost zero or had large relative errors (greater than 15%) were not included. Also it should be mentioned that the two application do not use the same number of organs. In the majority of the organs differences are significant. In the organs at the limits of the X-ray field results show that there is large difference in doses for the same field dimensions, however not monotonically, approaching 90% or larger. The difference is smaller (25% on average) in the averaged whole body dose

s s Differences on organ dose were expect because of the type and dimensions of phantoms, however mostly depend on whether or not the organ is included within the x-ray field. PCXMC and CALDose-X applications are useful tools for dose estimation, regarding the simlicity in their usage.