Number of Positive Specimens Percent Positive Number of Positive Specimens National Center for Immunization & Respiratory Diseases 2016-17 Surveillance Overview Lynnette Brammer, MPH Epidemiologist, Influenza Division National Adult and Influenza Immunization Summit May 11, 2017 Influenza Positive Tests Reported to CDC 2016-2017 Season Clinical Laboratories Public Health Laboratories 12000 10000 8000 6000 4000 2000 0 A B Percent Positive % Positive Flu A % Positive Flu B 26 25 24 23 22 21 20 19 18 17 16 15 14 13 12 11 10 9 8 7 6 5 4 3 2 1 0 4,000 3,500 3,000 2,500 2,000 1,500 1,000 500 0 A (subtyping not performed) A (H1N1)pdm09 A (H3N2) H3N2v B (lineage not performed) B (Victoria Lineage) B (Yamagata Lineage) Week Week 2017 National Adult and Influenza Immunization Summit 5/11/2017 1
Sequence Results, by Genetic Group, of Specimens Submitted to CDC by U.S. Public Health Laboratories, Cumulative, 2016-2017 season Influenza Positive Specimens Reported by U.S. Public Health Laboratories, Cumulative, 2016-2017 season 1816 3C.3a 58 5% Influenza A (H3) 1747 4059 339 846 3C.2a 1,031 95% 29804 Influenza A (H3) Influenza A (H1pdm09) Influenza A (subtype unknown) Influenza B Victoria Influenza B Yamagata Influenza B (lineage not determined) Antigenic Characterization of U.S. Influenza Viruses Collected October 1, 2016 to Present A (H1N1)pdm09: 251 of 253 (99.2%) of viruses antigenically characterized using ferret post-infection antisera are A/California/07/2009-like, the H1N1 component of the 2016-17 vaccine A(H3N2): 625 of 647(96.6%) were antigenically characterized as A/Hong Kong/4801/2014-like, the H3N2 component of the 2016-17 vaccine B/Victoria linage: 240 of 267 (89.9%) were antigenically characterized as B/Brisbane/60/2008-like, which is included in both quadrivalent and trivalent influenza vaccines for the 2016-17 season B/Yamagata lineage: All 312 were antigenically characterized as B/Phuket/3073/2013-like, an influenza B virus included in the quadrivalent influenza vaccines for the 2016-17 season 2017 National Adult and Influenza Immunization Summit 5/11/2017 2
% of Visits for ILI Percentage of Visits for Influenza-like Illness (ILI), 2016-2017 and Selected Previous Seasons 8 7 6 2015-16 Season 2014-15 season 2011-12 season 2009-10 season National Baseline 2016-17 season 5 4 3 2 1 0 40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38 Week Laboratory-Confirmed Influenza Hospitalizations Cumulative October 1, 2016 April 15, 2017 2017 National Adult and Influenza Immunization Summit 5/11/2017 3
Pneumonia and Influenza Mortality NCHS Mortality Surveillance System, September 30, 2012 April 8, 2017 Novel Influenza A Virus Infection: United States, 2016-17 Season Human infection with an influenza A virus that is different from currently circulating human seasonal viruses Influenza A (H1N2)v Iowa Not hospitalized, fully recovered Close contact with swine in week prior to illness onset No human-to-human transmission 2017 National Adult and Influenza Immunization Summit 5/11/2017 4
Novel Influenza A Virus Infection: United States, 2016-17 Season Influenza A (H7N2) New York City Not hospitalized, fully recovered Close, prolonged, unprotected exposure to sick cats infected with H7N2 No human-to-human transmission First H7N2 infection in humans in the U.S. since 2003 First known human infection with an influenza virus likely acquired through exposure to a cat Influenza Positives Reported to WHO FluNet, 2016-17 2017 National Adult and Influenza Immunization Summit 5/11/2017 5
Influenza Positives Reported to WHO FluNet, 2016-17 Human H7N9 Infections in China 2017 National Adult and Influenza Immunization Summit 5/11/2017 6
H7N9 in poultry in the United States 2017 HPAI H7N9 detected at 2 commercial poultry farms in Tennessee LPAI H7N9 detected in commercial or backyard poultry in Alabama (6), Georgia (1), Kentucky (2), and Tennessee (3) These are North American lineage H7N9 Different than the Asia H7N9 viruses Summary The 2016-17 influenza season in the United States was moderately severe Influenza A(H3N2) viruses predominated but influenza B viruses were more common in the Spring International picture similar to the United States The majority of viruses were similar to the 2016-17 Northern Hemisphere vaccine components Human infections with avian influenza viruses, most notably H7N9, continue to occur No significant changes in the epidemiology of human cases 2017 National Adult and Influenza Immunization Summit 5/11/2017 7
For more information, contact CDC 1-800-CDC-INFO (232-4636) TTY: 1-888-232-6348 www.cdc.gov The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. 2017 National Adult and Influenza Immunization Summit 5/11/2017 8