9/28/217 Great Debates Evidence-Based Practice: Specific Methods and/or Therapeutic Relationship? Scott D. Miller and William R. Miller Presentation slides from William Miller Increasing pressure to use evidence-based treatment methods Developing lists of approved specific treatment methods Practice and reimbursement increasingly limited to approved methods This is the norm in medical care 1. When bona fide treatments are directly compared, typically modest or no clinically meaningful outcome differences are found 1 8 6 4 2-2 -1 4 6 7 8 9 1 11 12 13 14 1 CBT MET TSF But do you really believe that: No specific treatment is better than any other? It doesn t matter what we do? Included all (N=361) comparative clinical trials of treatments for alcohol use disorders with 71,936 participants For 46 specific treatments with >3 trials: Computed a cumulative evidence index (CEI) With each study weighted for: 1. Methodological quality of research (1-17) 2. Strength of causal imputation (1-2) 3. Direction of finding (+ or -) Each study contributes + or score to CEI Miller, W. R., & Wilbourne, P. L. (22). Mesa Grande: A methodological analysis of clinical trials of treatment for alcohol use disorders. Addiction, 97(3), 26-277. 1
9/28/217 3 3 2 2 1 1 314 Brief Intv 189 MET 116 11 1 Acamprosate CRA Naltrexone 69 64 9 Social Skills Contracting BSCT 44 33 Beh Marital Case Mgmt - -1-1 -2-2 -3-3 -4-4 Anti-Anx Milieu Flagyil Non-SSRI Video SC -98-12 -13-14 -18 Relaxation -12 Confrontation -192 Psychotherapy -27 General Cslg -284 Alc Education -428 13 concerned family members randomly assigned to one of three interventions (all 12 hrs of contact) To engage unmotivated drinkers in treatment Al-Anon Facilitation Therapy (AFT) Johnson Institute Intervention (JII) Community Reinforcement (CRAFT) Miller, W. R., Meyers, R. J., & Tonigan, J. S. (1999). Engaging the unmotivated in treatment for alcohol problems: A comparison of three strategies for intervention through family members. Journal of Consulting and Clinical Psychology, 67, 688-697. 7 6 4 3 2 1 Al-Anon Johnson CRAFT 64.4 22. 13.6 p<.1 Average time to treatment entry: 47 days 8 76.7 7 6 8.6 4 29 3 2 1 CRAFT CRAFT+ Al-Anon P<.6 CRAFT = CRAFT+ CRAFT > Alabon 1 9 8 7 6 4 3 2 1 86 Sisson 1986 64 74 64 3 3 26 18 14 Miller 1999 Meyers 1999 Kirby 1999 68 Meyers 21 CRAFT Al-Anon Johnson Dutcher 29 67 Roozen 21 2
9/28/217 1. Few outcome differences for specific methods 2. Overall psychotherapy outcomes are good 7 multisite U.S. trials over 4 years (N=8,389) with >12 months of follow-up Remission Status: Continuous abstinence for 12 months 24.1 % Continuous moderation for 12 months 1.4 % Overall % days abstinent: 81.4% For all clients with any drinking: Abstaining on 7% of days Alcohol use decreased by 87% Miller, W. R., Walters, S. T., & Bennett, M. E. (21). How effective is alcoholism treatment in the United States? Journal of Studies on Alcohol, 62, 211-22. Treatment-as-usual is a high standard to beat Re-training can be challenging and expensive Specific treatment effect size often shrinks with dissemination into clinical practice Therapist belief / enthusiasm / style matters Testable question: Is it cost effective to re-train staff in an EBT? 1. Few outcome differences for specific methods 2. Overall psychotherapy outcomes are good 3. Average psychotherapy outcomes have not improved much for years 1 Armor et al. (1978) 8 U.S. Program sites N = 1,34 Uncontrolled treatment as usual 12-month outcomes 69% follow-up rate S.O. confirmation Project MATCH (1997) U.S. Outpatient sites N = 92 Manual-guided and closely supervised treatment 12-month outcomes 94% follow-up rate S.O. confirmation 2 18 16 14 12 1 8 6 4 2 16.7 19 % Abstinent at 12 Months 11.6 12.4 % Moderate at 12 Months.17 Drinks/Drinking Day Armor 1978 MATCH 1997 3
9/28/217.9.9 Percent Days Abstinent.8.7.6..4.3 MATCH Percent Days Abstinent.8.7.6..4.3 MATCH TAU Pre Months 1-3 Months 4-6 Pre Months 1-3 Months 4-6 Westerberg, V. S., Miller, W. R., & Tonigan, J. S. (2). Comparison of outcomes for clients in randomized versus open trials of treatment for alcohol use disorders. Journal of Studies on Alcohol, 61, 72-727 Westerberg, V. S., Miller, W. R., & Tonigan, J. S. (2). Comparison of outcomes for clients in randomized versus open trials of treatment for alcohol use disorders. Journal of Studies on Alcohol, 61, 72-727 1. Few outcome differences for specific methods 2. Overall psychotherapy outcomes are good 3. Outcomes have not improved for years 4. High variability of outcomes for therapists All therapists are equally effective? It doesn t matter who provides treatment? Treatment success is attributable to factors that are common to all therapists? Nine counselors trained and supervised together, all delivering the same manualguided behavior therapy for clients with alcohol use disorders Independently rated by three supervisors for level of accurate empathy (using observation scale developed by Truax & Carkhuff, 1967) Miller, Taylor & West (198) 24 4
9/28/217 Self-Help Condition 6 months 1 year 2 years r=.82 r=.71 r =.1 67% 2% 26% Moyers, T. B., & Miller, W. R. (213). Is low therapist empathy toxic? Miller & Baca (1983) Behavior Therapy 14: 441-448 Psychology of Addictive Behaviors, 27(3), 878-884. 2 26 Client Relapse Rates 4 3 3 2 2 1 1 38 3 29 23 24 2 19 18 1 13 11 6 Months 12 Months 18 Months 24 Months Follow-up Points Low Medium High 22 experienced therapists who treated at least 1 clients Delivering a manual-guided 16-week Combined Behavioral Intervention for alcohol use disorders All trained together and closely supervised Outcome: Average percent days abstinent for each therapist s clients through 12 months of follow-up Journal of the American Medical Association, 26, 29, pp. 23-217 12 1 Clients Outcomes by Therapist in the COMBINE Study Each line represents at least 1 clients Percent Days Abstinent 8 6 4 2 Exposure to pharmacotherapy (naltrexone) Exposure to psychotherapy (CBI) Exposure to specific treatment modules in CBI Mood Management Coping with Craving Social and Recreational Counseling Above-average therapist empathy (independent of specific treatment modules) Mean PDA Baseline Mean PDA Week 4 Mean PDA Week 26 Mean PDA Week 2 Mean PDA Week 68 Moyers, T. B., Houck, J. M., Rice, S. L., Longabaugh, R., & Miller, W. R.(216). Therapist empathy, Combined Behavioral Intervention, and alcohol outcomes in the COMBINE research project. Journal of Consulting and Clinical Psychology, 84(3), 221-229.
9/28/217 Therapists have a large effect on outcome Whether in manual-guided specific treatment or uncontrolled treatment as usual Example therapist factors: Accurate empathy Positive expectancy/hope Compassion / warmth / unconditional regard In fact, evidence-based psychotherapies are inseparable from therapists who provide them Miller, W. R., & Moyers, T. B. (21). The forest and the trees: Relational and specific factors in addiction treatment. Addiction, 11(3), 41-413. What therapist factors (skills / behaviors / attitudes) predict positive client outcomes? Such factors are not common to all therapists, but highly variable Calling them non-specific just means that we have not done our homework Specifiable, reliably measurable, learnable This is what Carl Rogers was searching for more than 6 years ago Well specified attitude and skill Reliably measurable Learnable skill improves with training Initial (at hiring or post-training) level of empathy predicts subsequent in-session level High in-session empathy predicts better client outcomes (e.g., in behavior therapy) Low empathy worse than no therapy Hire empathic therapists! 36 6