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Title: Endotracheal intubation following the bag valve mask (BVM) when assisting ventilations for a pediatric patient. Reported by: Martha Helmers 2 nd Party appraiser: Clinical Scenario: Two medics were dispatched to a baseball diamond for a ten-year-old female patient who had been struck on the back of the head with a baseball. The patient was reported to not be breathing. Upon arrival the paramedics found the young patient apneic with a strong carotid pulse. The ALS paramedic immediately preformed endotracheal intubation (ETI) on the young patient and the BLS paramedic followed this and performed assisted ventilations with the bag valve mask (BVM). The patient was transported to a nearby hospital. The young patient was discharged from the hospital within the month. Had this patient not been treated with ETI, but BVM only, would she have had the same outcome? P-I-C-O (Population Intervention Comparison- Outcome) Question: In pediatric patients, does addition of endotracheal intubation following the BVM when assisting ventilations provide superior care in the pre-hospital setting compared to using BVM alone? Search Strategy: (Child OR Children OR kids OR kid OR paediatric OR paediatrics OR pediatric OR pediatrics OR youth OR adolescents OR teens) AND (BVM OR bag valve mask OR pocket mask OR bagging) AND (ETI OR endotracheal intubation OR Endotracheal tube OR Endotracheal OR Intubation) *Reproducible search strategy found at the end* Search outcomes: 81 Results were found and reviewed; however, only 3 articles were deemed relevant on completion of reviewing the titles and the abstract of the articles found from Medline and Cinahl

Author & Date Gausche et al (2000) Relevant Papers: Population: Sample characteristics 830 patients age 12 years or younger Weighing less than 40kg Requiring airway management Design Outcomes Results Strengths / Weaknesses Controlled Clinical Trial Survival and neurological outcomes at hospital discharge No significant differences between the two methods were found ETI &BVM group: 110/416 (26% survival) BVM group: 123/404 (30% survival) ETI & BVM group 85/416 (20% good neurological outcome) BVM group 92/404 (23% good neurological outcomes) Strengths: -Total number of patients for the population size was large enough to conduct an effective study -Training was completed specific to the study; therefore all paramedics were conducting the procedures in very similar manners. Weaknesses: -the study was restricted to only two counties -The study was conducted in only urban areas where long transport times were not taken into account for survival rates. -For the procedural training for this study, only mannequins where used. -This could create a flaw in how well paramedics practiced ETI or creating a proper and affective mask seal on the patients.

Ehrlich et al (2004) 2,907 trauma patients Ages 19 and younger Retrospectiv e study Effectiveness of field ETI in rural pediatric trauma patients 105 out of 2,907 patients met study criteria 155 ETI s attempted on 105 children (1 to 6 per patient) 57% were attempted in the field. 22% attempted in transfer to hospital. 21% attempts in Trauma Center. Strengths: -large population size -Study was conducted in Rural West Virginia. This gives insight into ETI and its affectedness in a rural trauma transport in pediatric patients. -observations on the pediatric airway anatomy -Study was conducted over a long period of time to identify patients that fit criteria Successful intubation in the field 67% Successful intubation in the hospital 69% Subsequent failures 50% in the field 0% in the hospitals -Airway complications/multipl e ETI lead to transport delay lower GCS longer hospital stay Weaknesses: -Not limited to paramedics/pre-hospital preforming of endotracheal intubation -Flight RN s, ED physicians and anesthesiologist -Multiple failed attempts at ETI were recorded associated with longer transport time. -There was no specification on how the patient was being transported. -Multiple ETI attempts (complications) limited advantage over the BVM -possibly affect the outcome Stockinger and 5,773 trauma patients Retrospectiv e study The survival benefit of 5,773 patients enrolled in the study Strengths: -Population size is high

McSwain (2004) transported to the trauma center who had received ETI or BVM preforming pre-hospital endotracheal intubation on trauma patients of these patients 533 would receive ETI or BVM Age range included 2-97 years Receiving ETI - 316(5.5%) Receiving BVM 217(3.8%) Found that ETI patients experienced an increase in the transport time (22.0 vs 20.1 minutes p = 0.0241) -Study was conducted through a long period of time creating an advantage for accurate results -The study looked at several outcomes that could provide information based on the superiority of ETI -Focused on the Mortality and Mechanism of injury as well as pre-hospital time Weaknesses: -The groups for either receiving BVM and ETI could have been possibly different population groups -The ETI group could have been made upon a selection bias because of the more significant trauma associated with this population. Comments: Consideration should be made towards the fact that while this PICO question is based on pediatric patients only, the final article does not focus on pediatric patients but on all trauma patients. Furthermore, there was not much to be found in regards to pediatrics and ETI; but overall, the main study conclusions were that there should be a consideration that ETI causes more harm than good as well as increased scene time. Consider: Why would you not change practice based on this article? Considering that there are not many studies done on the topic of ETI in pediatric patients, further research is required before a definitive conclusion can be made. For the moment, there is therefore not enough evidence to change current practices in pre-hospital airway management. Clinical Bottom Line: Because of the minimal amount of research on ETI and the pediatric population, further studies should be conducted in order to get a concrete decision on whether ETI is a superior method over use of the bag valve mask on its own. References:

Ehrlich, P. F., Seidman, P. S., Atallah, O., Haque, A., & Helmkamp, J. (2004) Endotracheal intubations in rural pediatric trauma patients. Journal of Pediatric surgery 39 (9) DOI: 10.1016/j.jpedsurg.2004.05.010 Gausche, M., Lewis, R. J., Stratton, S. J., Haynes, B. E., Gunter, C. S., Poore, P. D., Seidel, J. S. (2000). Effect of out-of-hospital pediatric endotracheal intubation on survival and neurological outcome. Caring for the Critically Ill Patient, 283(6). DOI: 0.1001/jama.283.6.783 Stockinger, Z. & T., McSwain, N. E. (2004). Prehospital endotracheal intubation for trauma does not improve survival over bag-valve-mask ventilation. The Journal of Trauma, Injury, Infection, and Critical Care, 56 (3). DOI: 10.1097/01.TA.0000111755.94642.29 Reproducible search strategy: Searching: MEDLINE, CINAHL Search Search Terms Actions ID# S23 View Results (81) S11 AND S16 AND S22 S22 View Results (87,145) S17 OR S18 OR S19 OR S20 OR S21 S21 View Results (78,071) intubation S20 View Results (24,125) endotracheal S19 View Results (10,668) endotracheal tube S18 View Results (15,886) endotracheal intubation S17 View Results (1,244) ETI S16 View Results (1,307) S12 OR S13 OR S14 OR S15 S15 View Results (541) bagging S14 View Results (82) pocket mask S13 View Results (553) bag valve mask S12 View Results (258)

S11 S10 S9 S8 S7 S6 S5 S4 S3 S2 S1 BVM S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 adolescents youth pediatrics pediatric peadiatrics peadiatric kid kids children child View Results (2,945,292) View Results (208,616) View Results (81,268) View Results (753,837) View Results (753,837) View Results (65) View Results (158) View Results (13,522) View Results (12,208) View Results (1,447,614) View Results (2,257,292)