MAINTENANCE OF CERTIFICATION EXAMINATION IN NEUROMUSCULAR MEDICINE Content Blueprint (October 1, 2018)

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MAINTENANCE OF CERTIFICATION EXAMINATION IN NEUROMUSCULAR MEDICINE 2019 Content Blueprint (October 1, 2018) Number of questions: 170 1. Motor neuron disease (ALS, SMA, infectious/ postinfectious, paraneoplastic, 13-17% focal) 2. Root (cervical/thoracic/l-s [disc, spondylosis, tumor]) 4-6% 3. Plexus (brachial/lumbosacral [inflammatory, infectious, neoplastic, 4-6% trauma, congenital, hereditary, other]) 4. Nerve 28-32% A. Mononeuropathy (cranial, somatic, etc.) B. Mononeuropathy multiplex C. Axonal (drugs/toxins, paraneoplastic, infectious, inflammatory, hereditary, sarcoid, amyloid, porphyria, diabetes, etc.) D. Demyelinating/dysmyelinating disorders (inflammatory, infectious/postinfectious, hereditary, toxic, diabetes, paraprotein, paraneoplastic, etc.) E. Dorsal root ganglia (diabetes, nutritional, toxin, metabolic, inflammatory, hereditary, etc.) F. Autonomic (diabetes, amyloid, hereditary, etc.) 5. NMJ (MG, LEMS, botulism, toxins, congenital MG) 13-17% 6. Muscle (dystrophies [DMD, Becker, FSHD, LGD, myotonic, OPMD], inflammatory [PM, DM, IBM, sarcoid, HIV], metabolic/endocrine, toxic [statins], critical illness, congenital, mitochondrial, channelopathies, rhabdomyolysis [NMS, etc.], hyperckemia, floppy infant) 28-32% TOTAL 100% Note: A more detailed content outline is shown below. Neuromuscular Medicine 1 Posted: October 8, 2018

MAINTENANCE OF CERTIFICATION EXAMINATION IN NEUROMUSCULAR MEDICINE 2019 Content Outline Content Areas 01. Motor neuron disease (ALS, SMA, infectious/ postinfectious, paraneoplastic, focal) 4. Differential diagnosis 2. Pathology (nerve, muscle, skin, other) 6. Immunology 7. Comorbidity screening ii. Assistive devices iii. Assistive technology iv. Braces v. Physical therapy/occupational therapy vi. Pulmonary vii. Speech/swallowing viii. Nutritional management Neuromuscular Medicine 2 Posted: October 8, 2018

a. Initial b. End of life 02. Root (cervical/thoracic/l-s [disc, spondylosis, tumor]) 2. Pathology (nerve, muscle, skin, other) 6. Immunology 7. Comorbidity screening ii. Assistive devices/technology iii. Braces iv. Physical therapy/occupational therapy v. Pulmonary 03. Plexus (brachial/lumbosacral [inflammatory, infectious, neoplastic, trauma, congenital, hereditary, other]) Neuromuscular Medicine 3 Posted: October 8, 2018

2. Pathology (nerve, muscle, skin, other) 6. Immunology 7. Comorbidity screening ii. Assistive devices/technology iii. Braces iv. Physical therapy/occupational therapy v. Pulmonary 04. Nerve A. Mononeuropathy (cranial, somatic, etc.) B. Mononeuropathy multiplex C. Axonal (drugs/toxins, paraneoplastic, infectious, inflammatory, hereditary, sarcoid, amyloid, porphyria, diabetes, etc.) D. Demyelinating/dysmyelinating disorders (inflammatory, infectious/postinfectious, hereditary, toxic, diabetes, paraprotein, paraneoplastic, etc.) E. Dorsal root ganglia (diabetes, nutritional, toxin, metabolic, inflammatory, hereditary, etc.) F. Autonomic (diabetes, amyloid, hereditary, etc.) 1. Clinical a. Natural history/ prognosis b. Symptoms and physical findings Neuromuscular Medicine 4 Posted: October 8, 2018

c. Anatomy d. Epidemiology e. Differential diagnosis 2. Pathogenesis 3. Diagnostic testing a. Physiology/electrophysiology b. Pathology (nerve, muscle, skin, other) c. Genetics d. Imaging e. Laboratory testing f. Immunology g. Comorbidity screening 4. Management acute and chronic a. Symptom management/disease modification i. Pharmacology ii. Rehabilitation aa. Exercise bb. Assistive devices/ technology cc. Braces/orthotics dd. Physical therapy/ occupational therapy ee. Cardiopulmonary ff. Speech/swallowing gg. Nutritional management iii. Surgery aa. Nerve biopsy iv. Quality of life b. Ethics/professionalism c. Counseling 05. NMJ (MG, LEMS, botulism, toxins, congenital MG) Neuromuscular Medicine 5 Posted: October 8, 2018

i. Cholinesterase inhibitors ii. Immunomodulation iii. IV Ig b. Plasma exchange c. Ventilatory support d. Surgery i. Thymectomy ii. Tracheotomy e. Rehabilitation ii. Assistive devices/technology iii. Physical therapy/occupational therapy iv. Pulmonary v. Speech/swallowing vi. Nutritional management f. Quality of life 06. Muscle (dystrophies [DMD, Becker, FSHD, LGD, myotonic, OPMD], inflammatory [PM, DM, IBM, sarcoid, HIV], metabolic/endocrine, toxic [statins], critical illness, congenital, mitochondrial, channelopathies, rhabdomyolysis [NMS, etc.], hyperckemia, floppy infant) 2. Pathology (muscle, skin, other) 6. Ischemic lactate test Neuromuscular Medicine 6 Posted: October 8, 2018

7. Immunology 8. Comorbidity screening ii. Assistive devices iii. Assistive technology iv. Braces v. Physical therapy/occupational therapy vi. Pulmonary vii. Speech/swallowing viii. Nutritional management i. Muscle biopsy ii. Tendon release a. End of life Neuromuscular Medicine 7 Posted: October 8, 2018