Case Presentation: Indications for orbital decompression in TED: Modern surgical techniques for orbital decompression in TED: Inferomedial

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Case Presentation: Jonathan W. Kim, MD Director, Oculoplastic Surgery Stanford Medical Center 61 year old man with active Graves orbitopathy Visual acuity 20/30 OD 20/50 OS Left RAPD Bilateral optic disc edema Treated with oral prednisone for 6 months Orbital radiotherapy Visual acuity unchanged 8 weeks after radiotherapy Indications for orbital decompression in TED: Compressive optic neuropathy Vision 20/50 or worse Failed course of systemic steroids Failed course of orbital radiation Diabetic patient, unilateral proptosis Stable orbitopathy with significant proptosis?congestive orbitopathy Kikkawa et al. ASOPRS 2010 CAS score improved from 6.4 to 1.14 ( 3 months) Modern surgical techniques for orbital decompression in TED: Inferomedial Caruncular approach + inferior fornix Endoscopic Lateral wall Upper lid crease Lateral canthotomy Combination of the two approaches (e.g. Balanced decompression)

Inferomedial decompression: Caruncular approach: Decompression of posterior orbital floor and medial wall Transcaruncular approach -Hidden incision -exposes medial wall, orbital floor, roof Shorr et al. Ophthalmol 2000 Surgeon s view: Bony Landmarks in medial orbit: A) Orbital strut B) Ethmoidal artery

Posterior bony landmarks: Posterior inferomedial decompression through trans-caruncular incision: Attributes: -hidden, non-cutaneous incision -shortened surgery times vs lateral wall -Diplopia may occur in 10% of cases Indications: -Compressive optic neuropathy -Stable proptosis Compressive Optic Neuropathy: Inferomedial orbital decompression:

Lateral wall decompression: surgical results Deep lateral wall: anatomy 2000 Perry JD, Goldberg RA 19 patients undergoing lateral wall decompression 4.5 mm mean proptosis reduction 7% new onset diplopia 2004 Simon BG, Goldberg RA 201 decompressions performed at UCLA 3.4 mm proptosis reduction 2.6% new onset primary position diplopia Critical anatomic landmarks: Elements of successful lateral wall decompression: Preoperative planning CT scan Two assistants Equipment High speed drill 2, 3 mm burrs (acorn cutting, diamond polishing) Advantage: Lower rate of diplopia vs inferomedial approach Disadvantage: Not effective for compressive optic neuropathy

Summary: My recommendations Surgical options for decompression in 2010 Inferomedial through trans-caruncular or endoscopic approach Useful for both compressive optic neuropathy and stable orbitopathy Deep lateral wall lower diplopia rates Useful for stable orbitopathy Balanced decompression with both approaches when >4 mm of proptosis reduction needed Orbital fat decompression: Lacrimal keyhole: Olivari N. PRS 1991 6 cc of fat removed resulting in avg 5.9 mm of proptosis reduction (3.5% rate of new diplopia) Trokel et al. Ophthalmology 1993 Only 1.8 mm of avg proptosis reduction Wu, et al AJO 2008 Average 3.6 mm of proptosis reduction (2.8% diplopia) Currently used to augment results when combined with bony decompression Trans-caruncular - Inferomedial compartment Lateral wall inferolateral compartment Not recommended for inflamed orbits.

Diplopic space in greater wing of sphenoid bone: Deep lateral wall: greater wing of sphenoid bone Inferior orbitotomy: transconjunctival approach Useful surgical planes Septal plane, between fat pads and orbicularis Within the fat pads Commitment to a precise surgical plane is the key Surgical Plane= Color Change

Transconjunctival Approach: Achieving wide exposure Utilize a wide open sky incision Caruncle to canthus Visualize the periorbita at the orbital rim Anatomical Danger areas: Cornea Lid margin Canaliculus Medial fat pad Inferior oblique muscle Transconjunctival approach: Surgical Pearls Intra-septal plane: To maintain the same plane during dissection, follow the arc of the orbital fat pads Aim slightly anterior as dissect toward orbital rim Avoid skin perforation near orbital rim

Combined skin-skin/muscle flap: