PROOF. Advances in Oncology th Annual. September 30 - October 1, 2016 Hyatt Regency Sacramento, CA CONFERENCE DIRECTORS

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17 th Annual Advances in Oncology 2016 September 30 - October 1, 2016 Hyatt Regency Sacramento, CA (The September 25th conference is held at the Cancer Center Auditorium ) CONFERENCE DIRECTORS Helen K. Chew, M.D. Department of Internal Medicine UC Davis School of Medicine PRESENTED BY Scott Chistensen, M.D. Department of Internal Medicine Primo Lara, Jr., M.D. Department of Internal Medicine UC Davis School of Medicine SPONSORED BY: THE MEDICAL EDUCATOR CONSORTIUM

COURSE DESCRIPTION The 17th Annual Advances in Oncology program will bring together academic and community oncologists for the purpose of educating participants on the state-ofthe-art clinical management of a wide variety of solid and hematologic malignancies. The program is designed to update physicians and other cancer healthcare providers on recent advances and new diagnostic and treatment modalities in hematologic, breast, lung, gastrointestinal, and genitourinary cancers. This course is intended for physicians and cancer health care providers, including medical, surgical and radiation oncologists, nurses, physician assistants, pharmacists and other interested health care professionals. The conference includes didactic sessions from national oncology leaders and case-based panel discussions involving academic and community oncologists. EDUCATIONAL OBJECTIVES At the conclusion of this symposium, you should be able to: 1. Discuss advances in prognostic and predictive biomarkers and potential applications in therapeutic decision making. 2. Integrate targeted and traditional therapeutic modalities in the treatment of cancer. 3. Assess newly validated treatment options for patients with solid tumors or hematologic malignancies 4. Apply data from recent clinical trials to determine the optimal course of therapy in defined patient populations, with emphasis on novel agents including mtor inhibitors, ALK inhibitors, monoclonal antibodies, multi-targeted tyrosine kinase inhibitors, and inhibitors of cyclin kinase 4 and 6, among others. NEEDS ASSESSMENT The diagnosis, risk stratification, and multi-modality state-of-the-art treatment of hematologic and solid malignancies are rapidly evolving. The development of molecular prognostic assays and novel targeted therapies provides promising tools for personalized medicine. As a result of prior course participant evaluations and needs assessment surveys, the need for cutting edge information on prognostic markers and appropriate application of novel therapies has been identified. This year s conference will specifically address these needs in the common malignancies identified by past participants as essential to their practice, including solid and hematologic cancers. The timing of this meeting in the fall allows for the latest findings in clinical cancer research from major hematology and oncology conferences to be presented and discussed. This educational activity also meets a unique need for the Northern California Sacramento Valley to provide a group of networked and collaborating oncologists a forum to discuss the most recent developments in oncology care in the context of local treatment approaches, patient populations, and open clinical trials. The course is designed to change physician competence in oncology care. State of the art lectures and panel discussions from local and national oncologists will provide ample discussions on the applications and challenges of new prognostic tools and targeted and cytotoxic therapies. Pre-lecture and post-lecture audience response systems (evaluations) will be used in outcome measures. ACCREDITATION The Medical Educator Consortium is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. CREDIT HOURS The Medical Educator Consortium designates this live activity for a maximum of 8.5 AMA PRA Category 1 Credit(s). Physicians should only claim credit commensurate with the extent of their participation in the activity. DISCLOSURE The Medical Educator Consortium (MEC) adheres to the ACCME Standards for Commercial Support. All persons that will be in a position to control the content of the CME Activity are required to disclose all relevant financial relationships. Faculty disclosure forms outlining this information will be made available to all participants prior to educational activity. MEC has also implemented a mechanism to identify and resolve all conflicts of interest prior to the education activity being delivered to learners. The source of all support from commercial interests will also be disclosed to learners prior to the beginning of the educational activity. NURSING CONTINUING MEDICAL EDUCATION Continuing Medical Education is acceptable for meeting RN continuing education requirements, as long as the course is AMA PRA Category 1 Credits, and has been taken within the appropriate time frames.

Mehrdad Abedi, M.D. Associate Theresa R. Arciniega, LCSW Chief Licensed Clinical Social Worker Department of Clinical Social Services U.C. Davis Health System Mili Arora, M.D. Assistant Kristie Bobolis, M.D. Medical Oncologist Capitol Hematology-Oncology Helen K. Chew, M.D. Scott Christensen, M.D. David Cooke, M.D. Assoc. Program Director, Cardiothoracic Surgery Residency Division of Cardiothoracic Surgery UC Davis Medical Center Megan Daly, M.D. Department of Radiation Oncology David Gandara, M.D. Brian Jonas, M.D., Ph.D. Melissa Kaime, M.D. Medical Oncology Gene Upshaw Memorial Tahoe Forest Cancer Center Hagop Kantarjian, M.D. Department of Leukemia The University of Texas MD Anderson Cancer Center Primo N. Lara, Jr., M.D. Associate Director for Translational Research Benjamin Leavy, M.D. Associate Physician Family and Community Medicine UC Davis Medical Group FACULTY AND PANELISTS Anna Orlowski, JD Chief Health System Counsel UC Davis Health System Chong-Xian Pan, M.D. Associate Professor Ajithkumar Puthillath, M.D. Hematologist-Oncologist Stockton Hematology Oncology Jonathan Riess, M.D. Eve Rodler, M.D. Assistant Adjunct Professor Aaron Rosenberg, M.D. Philip Sardar, M.D. Hematologist/Oncologist Kaiser Permanente Candice Sauder, M.D. of Surgery Division of Surgical Oncology Thomas Semrad, M.D. Medical Oncology Gene Upshaw Memorial Tahoe Forest Cancer Center Samer Shihabi, M.D. Hematologist-Oncologist Mercy Medical Group Sandy Srinivas, M.D. Associate Stanford University Joseph Tuscano, M.D. Richard Valicenti, M.D. Professor and Chair Department of Radiation Oncology Stanley Yap, M.D. Department of Urology

X AGENDA FRIDAY, SEPTEMBER 30TH (FRIDAY ONLY at Cancer Center Auditorium UC Davis Comprehensive Cancer Center - no exhibits available on this day) 12:30 pm Welcome Lunch 1:00 pm Introduction of Keynote Speaker: The Lois O Grady Lectureship (Presentation of award to Dr. Hagop Kantarjian) Ted Wun, M.D. 1:10 pm O Grady Keynote Lecture: Dr. Hagop Kantarjian 1:55 pm Question and Answer session 2:00 pm Chronic Lymphocytic Leukemia: Novel Therapeutics Joseph Tuscano, M.D. 2:20 pm Multiple Myeloma: What are the Optimal Therapies in 2016? Aaron Rosenberg, M.D. 2:40 pm Update on Cellular Therapies for Hematologic Malignancies Mehrdad Abedi, M.D. 3:00 pm Panel Discussion: Practice Changing Developments in Benign and Malignant Hematology Moderator: Brian Jonas, M.D. Panel: Mehrdad Abedi, M.D., Hagop Kantarjian, M.D., Ajithkumar Puthillath, M.D., Aaron Rosenberg, M.D., Joseph Tuscano, M.D. 3:30 pm Q&A (Interactive Audience Participation): Benign and Malignant Hematology 3:35 pm End of Life Option Act: Medical Legal Considerations Anna Orlowski, JD 3:55 pm End of Life Option Act: Ethical Considerations Scott Christensen, M.D. 4:15 pm Panel Discussion: End of Life Option Act Moderator: Scott Christensen, M.D. Panel: Theresa Arciniega, LCSW, Benjamin Leavy, M.D., Anna Orlowski, JD 4:45 pm Adjourn for the day SATURDAY, OCTOBER 1 ST (SATURDAY ONLY at the Hyatt Regency Sacramento exhibits welcomed) 7:00 am Registration, Coffee, Visit Exhibits 7:15 am Breakfast & Learn Symposia (non cme) 8:30 am Welcome Remarks Primo N. Lara, Jr., M.D. and Helen K. Chew, M.D. 8:35 am Pre-session Survey Scott Christensen, M.D. 8:40 am Keynote Lecture #1: The Lois O Grady Lectureship Molecular Targets of Interest in Acute Leukemias Hagop Kantarjian, M.D. 9:20 am State of the Art in Genitourinary Cancers Sandy Srinivas, M.D. 9:40 am Panel Discussion: Challenging Cases in Genitourinary Cancers Moderator: Stanley Yap, M.D. Panel: Primo Lara, M.D., Chong-Xian Pan, M.D., Philip Sardar, M.D., Samer Shihabi, M.D., Richard Valicenti, M.D. 10:10 am Q&A (Interactive Audience Participation): Genitourinary Cancers 10:15 am Advances in Breast Cancer Therapeutics in the Adjuvant and Metastatic Settings Eve Rodler, M.D. 10:35 am Panel Discussion: Optimal Therapies in Breast Cancer Moderator: Helen Chew, M.D. Panel: Mili Arora, M.D., Kristie Bobolis, M.D., Candice Sauder, M.D., Scott Christensen, M.D., Melissa Kaime, M.D., Eve Rodler, M.D. 11:05 am Q&A (Interactive Audience Participation): Breast Cancer 11:10 am Visit Exhibits 11:20 am Lunch & Learn Symposia (non CME) 12:20 pm Coffee & Visit Exhibit 12:40 pm New Developments in Lung Cancer Therapeutics David Gandara, M.D. 1:00 pm Panel Discussion: Translating Results of Trials in Small Cell and Non-Small Cell Lung Cancer into Clinical Practice Moderator: Jonathan Riess, M.D. Panel: David Cooke, M.D., Megan Daly, M.D., David Gandara, M.D., Samer Shihabi, M.D. 1:30 pm Q&A (Interactive Audience Participation): Lung Cancer 1:35 pm Advances in Gastrointestinal Malignancies Thomas Semrad, M.D. 1:55 pm Clinical Updates in Solid Tumor Oncology Johnathan Riess, M.D. 2:15 pm Post-session Survey/Closing Remarks: Scott Christensen, M.D. 2:20 pm Adjourned

REGISTRATION FORM 17 th Annual Advances in Oncology 2016 Register online at www.meccinc.com or FAX to 305/675-2718. September 30 - October 1, 2016 Hyatt Regency Sacramento, CA Name Degree Address City State Zip Telephone ( ) FAX ( ) Email address Specialty Type of Practice: q Private q Academic q Hospital q Resident/Fellow I will be attending q BOTH days September 30 and October 1st q ONLY Friday September 30 at the Cancer Center Auditorium UC Davis Comprehensive Cancer Center q ONLY Saturday, October 1st at the Hyatt Regency Sacramento Registration fee $150 Physicians $ 75 Nurses, Fellows, Residents and Allied Health Care $250 Industry Professionals Refunds must be provided in writing prior to August 15, 2016. After August 15, 2016, No Refunds will be provided. A $50.00 administrative fee is charged on all refunds. Enclosed is my check i/a/o of for registration of this course. I authorize MECC to charge my credit card i/a/o $ for registration of this course using the following credit card. Name on Card Exp. Date Card number CVV Code Authorized signer CONFERENCE LOCATION This conference is held at two locations. No transportation will be provided from the host hotel. Friday, September 30th Saturday, October 1st HYATT REGENCY Cancer Center Auditorium 1209 L Street 4501 X Street Sacramento, CA 95814 Sacramento, CA 95817 Parking is available in the lot adjacent to the Cancer Center. For more information contact: CONFERENCE MANAGEMENT MECC 6619 South Dixie Highway, # 341, Miami, FL 33143 Telephone 305/663-1628 Office Fax 305/675-2718 Or visit our website at www.meccinc.com Email: tvalls@meccinc.com

17 th Annual Advances in Oncology 2016 September 30 - October 1, 2016 MECC, Inc. 6619 South Dixie Highway, # 341 Miami, Florida 33143 HYATT REGENCY 1209 L Street, Sacramento, CA 95814 PRSRT STD U.S. POSTAGE PAID MIAMI, FLORIDA PERMIT NO. 1429