Published over 200 peer-reviewed papers, mainly in refereed international scientific journals.

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Personal data Surname & First name Occupational field Clinical Activity Surgical Activity Mortini Pietro, M.D. Professor of Neurosurgery M.D., Specialist in Neurosurgery and ENT Surgery October 1 st 2008 - present Chairman, Neurosurgery Department and Radiosurgery Unit San Raffaele University Hospital and Scientific Institute, Milan October 1 st 2008 - present Professor of Neurosurgery Vita-Salute San Raffaele University, Milan November 1 st 2005 September 1 st 2008 Chairman Neurosurgery Unit Spedali Civili University Hospital, Brescia October 1 st 2005 September 1 st 2008 Consultant Neurosurgeon, Department of Neurosurgery San Raffaele University Hospital and Scientific Institute, Milan 2002 Director Skull Base Surgery Section, Department of Neurosurgery San Raffaele University Hospital and Scientific Institute, Milan 2001 Senior Active Staff member, Department of Neurosurgery San Raffaele University Hospital and Scientific Institute, Milan 1996-2005 Consultant Neurosurgeon at the Department of Neurosurgery Lodi County Hospital, Lodi 1992-2000 Active Staff member, Department of Neurosurgery San Raffaele University Hospital and Scientific Institute, Milan - 1991 Resident in Neurosurgery, Department of Neurosurgery University Hospital, Verona To date: 7374 micro neuro-surgical procedures performed as first operator and specifically 4.169 surgeries for intracranial tumours and vascular malformations, 2.087 transfenoidal procedures for sellar and suprasellar tumours, 1.014 spinal intradural and extradural procedures for tumours, 104 other procedures for hydrocephalus, infectious conditions and biopsy. Stereotactic Gamma Knife radio-surgical procedures on Perfexion equipment. Research Activity Publications Published over 200 peer-reviewed papers, mainly in refereed international scientific journals. Page 1/5

Experimental Activities Director: Unit of Experimental Neurosurgery, San Raffaele Scientific Institute, Milan Pre-Clinical study on olfactory cell transplantation in spinal cord injuries Pre-clinical study on use of collagen scaffold in spinal cord and peripheral nerves injuries (PON #2 RINOVATIS) Collaborations Ongoing Collaborations Scientific Societies Membership Scientific Reviewer 2005 - present Department of Bioengineering - University of Lecce, Harvard Medical School - Boston, Massachusetts Institute of Technology - Boston and Dept. of Neurology - Vita-Salute San Raffaele University Milan : research study on applications of collagen scaffolds for the treatment of nervous system injuries 2000 - present Institute of Medical Genetics University of Milan: research study on cytogenetic of skull base chordomas 1996 - present The Max Plank Istitut für Psychiatrie of Munchen (Germany): research study on pathology of the pituitary tumours 1992 - present The Chair of Maxillo-facial surgery of the University of Milan: research study on new surgical techniques for the treatment of craniofacial malformation and craniofacial tumours 1992 - present Member of the Pituitary Unit (research unit officially recognized by the International Advisory Board of the Neuroscience Department - San Raffaele Scientific Institute) Clinical and Basic Research The George Washington University - Washington D.C. and Harvard Medical School, Boston Massachusetts Institute of Technology Boston Max-Planck-Institut für Psychiatrie, Munchen (Germany) Department of Neurology, Dept. of Neurosurgery, Dept. of ENT Surgery, Dept. of Endocrinology and Dept. of Pathology Vita/Salute San Raffaele University, Milan Department of Maxillofacial Surgery, Institute for Medical Genetics - University of Milan Department of Bioengineering - University of Lecce 1998 2005 Member of the Scientific Committee of the Italian Skull Base Society Congress of Neurological Surgeons European Society for Skull Base Surgery Italian Society for Skull Base Surgery Italian Society for Neurosurgery Pituitary (PITU), Editor-in-Chief Dr. Shlomo Melmed Page 2/5

Member of the editorial board Journal of Neurosurgical Sciences The International Neuroscience Journal Academic appointments and Teaching activity University From 2015 Director, International University Master in Gamma Knife Radiosurgery, Vita- Salute San Raffaele University School of Medicine, Milan 2015 Professor of neurophysiology, Course on Clinical application of Tissue Engineering DHITECH Technology and High-tech district (Lecce) 15/07/2011 to date Member of the Dean Committee of Vita-Salute San Raffaele University School of Medicine, Milan 2010 to date Member of the Technical Commission - Cooperation Agreement between the University of Extremadura (Spain) and Vita-Salute San Raffaele University 2012 to date Member of the Technical Commission - Cooperation Agreement between the George Washington University and Vita-Salute San Raffaele University 2008 to date Director Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan 2008 to date Full time professor, Vita-Salute San Raffaele University, Milan 2007 to date Clinical Professor of Neurosurgery 2005-2008 Director Residency Program in Neurosurgery, University of Brescia 2005-2008 Full time professor, University of Brescia 2004-2005 Associate Professor of Neurosurgery, University of Brescia 2004-2005 Professor of Clinical Neuroanatomy, Vita-Salute San Raffaele University, Milan September 2004 Visiting Professor of Neurosurgery, Residency Program October 2002 Visiting Professor of Neurosurgery, Residency Program 2000-2002 Professor of Clinical Neurosurgery School of Medicine, Vita-Salute San Raffaele University, Milan 2000-2002 Professor of Surgical Anatomy of the Skull and the Brain School of Medicine, Vita-Salute San Raffaele University, Milan Page 3/5

2000-2002 Professor of Clinical Neurosurgery 1995 2000 Tutor of Clinical Neurosurgery 1999 2000 Tutor of Neurosurgery - School of Medicine and Residency Program University of Milan (Policlinic Hospital, San Raffaele Hospital, Sacco Hospital) University of Milan Bicocca/San Gerardo Hospital, Monza 1994-2000 Instructor of Neuroanatomy, Chair of Human Anatomy University of Milan 1992-1996 Instructor of Neuroanatomy 1990 1996 Professor of Neurosurgery School of Nursing - University Hospital in Verona and at San Raffaele University Hospital in Milan Italian Ministry of Health (MoH) 2010-2011 Member of the Joint Commission for cooperation activities among Italy and Malta 2011 Technical advisor for the Italian Ministry of Health for neurosurgery and tissue engineering Organizer, instructor, lecturer in courses in National and International meetings. Education 2000 Diploma as ENT Surgery specialist with top marks - University of Milan, Milan 1991 Diploma as Neurological Surgery specialist with top marks - University of Verona, Verona First class medical degree Cum Laude and university honour, Doctor of Medicine and Surgery - University of Parma, Parma 1980 High School Certificate (Diploma di maturità classica) Classical Lyceum Page 4/5

Additional Licensure and Professional Registrations Italian license to practice medicine and surgery with top marks - University of Parma, Parma 2005 Swiss licence to practice medicine and surgery as specialist in Neurosurgery 2014 Full registration with a licence to practice and entry on Specialist Register/Specialty Neurosurgery General Medical Council (UK) GMC reference number 7480397 Focus Clinical and Research Educational Experiences Other personal skills and Competences 1999 International Fellowship. Research activity at the Minimally Invasive Surgery skull Base Training Center on microsurgical and endoscopic skull base approaches for clival tumours, vascular microsurgical and EC/IC by-pass training. Prof L. N. Sekhar, Department of Neurosurgery, The George Washington University Neurological Institute, Washington D.C. 1995 Training on surgical techniques for the control of vertebral artery in the treatment of vascular and tumoral pathologies of the skull base, the cranio cervical junction and the cervical spine. Prof. B.George, Department of Neurosurgery, Hôspital Lariboisiére, Paris (France) 1989 Experimental and clinical researches on calcium channel blockers in SAH related vasospasm. Prof N. Kassel. Training in Stereotactic radiosurgery, Prof. L. Steiner. Department of Neurosurgery, Virginia University, Charlottesville. Training in Neurotrauma Prof Miller D, Department of Neurosurgery, Western General Hospital, University of Edinburgh, Edinburgh (UK). 2008 Surgical instruments set for microsurgery of skull base. See: K. Storz catalogue Instruments according to Prof. P. Mortini Patents CA 2778238 Collagen Scaffold in nervous system regeneration - 2012 US20120214222 A1 Method for manufacturing a device for regenerating biological tissues, specifically for regenerating tissues of the central nervous system Page 5/5