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Material Safety Data Sheet MSDS Update: 04/17/2012 Version: 1.0 Date Printed: SECTION 1 - Chemical Product & Company Identification Product Name Solubility and Stability Screen HT Product Number HR2-072 Company Hampton Research Street Address 34 Journey City, State, Zip, Country Aliso Viejo, CA 92656-3317, U.S.A. Technical Phone 949 425 1321 Fax 949 425 1611 Emergency Phone 949 425 1321 For CHEMTREC Assistance, call: 800 424 9300 For International CHEMTREC Assistance, call: 703 527 3887 SECTION 2 - Composition / Information on Ingredient Substance Name Formula M r CAS # EC No SARA RTECS LD50 (2-Hydroxypropyl)-β-cyclodextrin 1,396 128446-35-5 420-920-1 No 1,2-Propanediol C 3 H 8 O 2 76.09 57-55-6 200-338-0 No TY2000000 1-Butyl-3-methylimidazolium chloride 1-Ethyl-3-methylimidazolium acetate C 8 H 15 ClN 2 174.67 79917-90-1 No C 8 H 14 N 2 O 2 170.21 143314-17-4 No 4-Aminobutyric acid (GABA) C 4 H 9 NO 2 103.12 56-12-2 200-258-6 No ES6300000 5-Aminovaleric acid C 5 H 11 NO 2 117.15 660-88-8 211-544-5 No 20,000 mg/kg 50-300 mg/kg 12,680 mg/kg 6-Aminohexanoic acid C 6 H 13 NO 2 131.18 60-32-2 200-469-3 No MO6300000 14,300 mg/kg 6-O-α-D-Maltosyl-β-cyclodextrin C 54 H 90 O 45 1,459.27 104723-60-6 No Acetamide C 2 H 5 NO 59.07 60-35-5 200-473-5 Yes AB4025000 Adipic acid C 6 H 10 O 4 146.14 124-04-9 204-673-3 AU8400000 7,000 mg/kg 11 g/kg Ammonium acetate C 2 H 7 NO 2 77.08 631-61-8 211-162-9 No AF3675000 Ammonium chloride NH 4 Cl 53.49 12125-02-9 235-186-4 Yes BP4550000 1,650 mg/kg Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 1 of 13

(CONTINUED) - SECTION 2 - Composition / Information on Ingredient Substance Name Formula M r CAS # EC No SARA RTECS LD50 Ammonium sulfate H 8 N 2 O 4 S 132.14 7783-20-2 231-984-1 Yes BS4500000 Benzamidine hydrochloride C 7 H 8 N 2 HCl 156.62 1670-14-0 216-795-4 No CV6260000 Intraperitoneal - mouse - 580 mg/kg Betaine monohydrate C 5 H 11 NO 2 H 2 O 135.16 590-47-6 203-490-6 No Cadmium chloride hydrate CdCl 2 xh 2 O 183.32 654054-66-7 233-296-7 Yes Calcium chloride dihydrate CaCl 2 2H 2 O 147.01 10035-04-8 233-140-8 No EV9810000 Cesium chloride CsCl 168.36 7647-17-8 231-600-2 No FK9625000 2,600 mg/kg Cholin acetate C 7 H 17 NO 3 163.22 14586-35-7 No Cobalt(II) chloride hexahydrate CoCl 2 6H 2 O 237.93 7791-13-1 231-589-4 Yes GG0200000 D-(+)-Trehalose dihydrate C 12 H 22 O 11 2H 2 O 378.33 6138-23-4 202-739-6 No DL-Malic acid ph 7.0 C 4 H 6 O 5 134.09 6915-15-7 230-022-8 No ON7175000 D-Sorbitol C 6 H 14 O 6 182.17 50-70-4 200-061-5 No LZ4290000 766 mg/kg 4,600 mg/kg 1,600 mg/kg 15,900 mg/kg Ethylammonium nitrate C 2 H 9 N 2 O 3 108.11 22113-86-6 Ethylene glycol C 2 H 6 O 2 62.07 107-21-1 203-473-3 Yes KW2975000 Ethylenediamine dihydrochloride C 2 H 8 N 2 2HCl 133.02 333-18-6 206-369-6 No KV3850000 Ethylenediaminetetraacetic acid disodium salt dihydrate C 10H 14 N 2 Na 2 O 8 2H 2 O 372.24 6381-92-6 205-358-3 No AH4410000 Formamide CH 3 NO 59.07 75-12-7 200-842-0 No LQ0525000 Gadolinium(III) chloride hexahydrate Cl 3 Gd 6H 2 O 371.70 13450-84-5 233-386-6 No LW4050000 Glutaric acid C 5 H 8 O 4 132.12 110-94-1 203-817-2 No MA3740000 4,700 mg/kg 1,620 mg/kg > 2,000 mg/kg 5,577 mg/kg Intraperitoneal - mouse - 669 mg/kg 6,000 mg/kg Glycerol C 3 H 8 O 3 92.09 56-81-5 200-289-5 No MA8050000 Glycine C 2 H 5 NO 2 75.07 56-40-6 200-272-2 No MB7600000 7,930 mg/kg Gly-gly C 4 H 8 N 2 O 3 132.12 556-50-3 209-127-8 No Gly-gly-gly C 6 H 11 N 3 O 4 189.17 556-33-2 209-122-0 No GSH (L-Glutathione reduced) GSSG (L-Glutathione oxidized) C 10 H 17 N 3 O 6 S 307.33 70-18-8 200-725-4 No MC0556000 C 20 H 32 N 6 O 12 S 2 612.64 27025-41-8 200-578-6 No 5,000 mg/kg > 5,000 mg/kg Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 2 of 13

(CONTINUED) - SECTION 2 - Composition / Information on Ingredient Substance Name Formula M r CAS # EC No SARA RTECS LD50 Guanidine hydrochloride CH 5 N 3 HCl 95.53 50-01-1 200-002-3 No Hydroxyectoine C 6 H 10 N 2 O 3 158.16 165542-15-4 No Hypotaurine C 2 H 7 NO 2 S 109.15 300-84-5 No L-Argininamide dihydrochloride C 6 H 15 N 5 O 2HCl 246.14 14975-30-5 200-659-6 Yes L-Arginine C 6 H 14 N 4 O 2 174.20 74-79-3 200-811-1 No CF1934200 L-Arginine ethyl ester dihydrochloride C 8 H 18 N 4 O 2 2HCl 275.18 36589-29-4 No L-Glutamic acid C 5 H 9 NO 4 147.13 56-86-0 200-293-7 No L-Histidine C 6 H 9 N 3 O 2 155.16 71-00-1 200-745-3 No MS3070000 Lithium chloride LiCl 42.39 7447-41-8 231-212-3 No OJ5950000 Lithium citrate tribasic tetrahydrate C 6 H 5 Li 3 O 7 4H 2 O 281.99 6080-58-6 213-045-8 No Lithium nitrate LiNO 3 68.95 7790-69-4 232-218-9 No QU9330000 > 30,000 mg/kg > 15,000 mg/kg 526 mg/kg L-Proline C 5 H 9 NO 2 115.13 147-85-3 205-702-2 No TW3584000 L-Serine C 3 H 7 NO 3 105.09 56-45-1 200-274-3 No VT8100000 Magnesium chloride hexahydrate MgCl 2 6H 2 O 203.3 7791-18-6 232-094-6 No OM2975000 8,100 mg/kg Magnesium sulfate hydrate MgSO 4 aq 120.37 22189-08-8 231-298-2 No Methyl-β-cyclodextrin 1320 128446-36-6 No Methyl α-d-glucopyranoside C 7 H 14 O 6 194.18 97-30-3 202-571-3 No N-Ethylurea C 3 H 8 N 2 O 88.11 625-52-5 210-898-8 No YT2335000 N-Methylformamide C 2 H 5 NO 59.07 123-39-7 204-624-6 No LQ3000000 4,000 mg/kg N-Methylurea C 2 H 6 N 2 O 74.08 598-50-5 209-935-0 No YT7175000 Non Detergent Sulfobetaine 195 (NDSB-195) Non Detergent Sulfobetaine 201 (NDSB-201) Non Detergent Sulfobetaine 211 (NDSB-211) Non Detergent Sulfobetaine 221 (NDSB-221) C 7 H 17 NO 3 S 195.3 160255-06-1 No C 8 H 11 NO 3 S 201.2 15471-17-7 239-491-3 No C 7 H 17 NO 4 S 211.28 38880-58-9 254-176-0 No C 9 H 19 NO 3 S 221.3 160788-56-7 No Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 3 of 13

(CONTINUED) - SECTION 2 - Composition / Information on Ingredient Substance Name Formula M r CAS # EC No SARA RTECS LD50 Non Detergent Sulfobetaine 256 (NDSB-256) C 12 H 19 NO 3 S 257.4 81239-45-4 No Oxalic acid dihydrate C 2 H 2 O 4 2H 2 O 126.07 6153-56-6 205-634-3 No Pentaerythritol ethoxylate (15/4 EO/OH) C 7 H 18 O 6 ~ 797 30599-15-6 500-071-2 No Polyethylene glycol 200 (C 2 H 4 O) n H 2 O ~ 200 25322-68-3 500-038-2 No TQ3600000 Polyethylene glycol 3,350 Polyethylene glycol 8,000 Polyethylene glycol monomethyl ether 550 Polyethylene glycol monomethyl ether 750 Polyethylene glycol monomethyl ether 1,900 (C 2 H 4 O) n H 2 O (C 2 H 4 O) n H 2 O 3,300-3,400 7,000-8,000 25322-68-3 500-038-2 No 25322-68-3 500-038-2 No TQ4105000 CH 3 (OCH 2 CH 2 ) n OH ~ 550 9004-74-4 215-801-2 No PE8271000 ~ 750 9004-74-4 ~ 1,900 9004-74-4 Polypropylene glycol P 400 C 3 H 8 O 2 25322-69-4 500-039-8 No TR5250000 Polyvinylpyrrolidone K 15 (C 6 H 9 NO) n ~ 10,000 9003-39-8 201-800-4 No TR8370000 Potassium chloride KCl 74.55 7447-40-7 231-211-8 No TS8050000 30,200 mg/kg > 50,000 mg/kg 39800 ul/kg > 2,000 mg/kg 100000 mg/kg Potassium phosphate dibasic K 2 HPO 4 174.18 7758-11-4 231-834-5 No Potassium thiocyanate KSCN 97.18 333-20-0 206-370-1 No XL1925000 Sodium benzenesulfonate C 6 H 5 NaO 3 S 180.16 515-42-4 208-198-2 No DB7350000 Sodium bromide NaBr 102.89 7647-15-6 231-599-9 No VZ3150000 Sodium chloride NaCl 58.44 7647-14-5 231-598-3 No VZ4725000 854 mg/kg 9,378 mg/kg 3,500 mg/kg 3,000 mg/kg Sodium malonate ph 7.0 C 3 H 4 O 4 104.06 141-82-2 205-503-0 No OO0175000 Sodium phosphate monobasic monohydrate NaH 2 PO 4 H 2 O 137.99 10049-21-5 231-449-2 No Sodium p-toluenesulfonate CH 3 C 6 H 4 SO 3 Na 194.18 657-84-1 211-522-5 No XT7350000 Sodium sulfate decahydrate Na 2 SO 4 10H 2 O 322.2 7727-73-3 231-820-9 No 1310 mg/kg Intravenous - mouse - 1,700 mg/kg Spermidine C 7 H 19 N 3 145.25 124-20-9 204-689-0 No EJ7000000 Spermine tetrahydrochloride C 10 H 26 N 4 4HCl 348.19 306-67-2 206-189-8 No EJ7230000 Succinic acid ph 7.0 C 4 H 6 O 4 118.09 110-15-6 203-740-4 No WM4900000 2,260 mg/kg Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 4 of 13

(CONTINUED) - SECTION 2 - Composition / Information on Ingredient Substance Name Formula M r CAS # EC No SARA RTECS LD50 Sucrose C 12 H 22 O 11 342.30 57-50-1 200-334-9 No WN6500000 29,700 mg/kg Tacsimate ph 7.0 Taurine C 2 H 7 NO 3 S 125.15 107-35-7 203-483-8 No WX0175000 TCEP hydrochloride C 9 H 15 O 6 P HCl 286.65 51805-45-9 No Tetraethylammonium bromide (CH 3 CH 2 ) 4 NBr 210.16 71-91-0 200-769-4 No BS5950000 5,000 mg/kg 3,500 mg/kg 2,000 mg/kg Trichloroacetic acid Cl 3 CCOOH 163.39 76-03-9 No Triethylene glycol C 6 H 14 O 4 150.17 112-27-6 203-953-2 No YE4550000 Trimethylamine N-oxide dihydrate C 3 H 9 NO 2H 2 O 111.14 62637-93-8 214-675-6 No YH2850000 17,000 mg/kg 8,700 mg/kg Tryptone 91079-40-2 293-428-4 No Urea CH 4 N 2 O 60.06 57-13-6 200-315-5 No YR6250000 8,471 mg/kg Water Xylitol C 5 H 12 O 5 152.15 87-99-0 201-788-0 No α-cyclodextrin C 36 H 60 O 30 972.86 10016-20-3 233-007-4 No 16,500 mg/kg Intravenous - rat - 788 mg/ kg β-alanine C 3 H 7 NO 2 89.09 107-95-9 203-536-5 No β-cyclodextrin C 42 H 70 O 35 1,134.98 7585-39-9 231-493-2 No 18,800 mg/kg = NOT AVAILABLE SECTION 3 - Hazards Identification HMIS RATING HAZARD RATINGS HEALTH HAZARD: 0 0 - LEAST FLAMMABILITY: 0 1 - SLIGHT REACTIVITY: 0 2 - MODERATE 3 - HIGH NFPA RATING 4 - EXTREME HEALTH HAZARD: 0 FLAMMABILITY: 0 REACTIVITY: 0 For additional information on toxicity, please refer to SECTION 11. Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 5 of 13

SECTION 4 - First Aid Measures GENERAL ADVICE Consult a physician. Show this safety data sheet to the doctor in attendance. ORAL EXPOSURE If swallowed, wash out mouth with water provided person is conscious. DO NOT INDUCE VOMITING. Call a physician. INHALATION EXPOSURE If inhaled, remove to fresh air. If breathing is difficult, GIVE OXYGEN. Call a physician. DERMAL EXPOSURE In case of contact, immediately wash skin with soap and copious amounts of water for at least 15 minutes. Take off contaminated clothing and shoes immediately. Call a physician. EYE EXPOSURE In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician. SECTION 5 - Fire Fighting Measures FLASH POINT AUTOIGNITION TEMPERATURE FLAMMABILITY EXTINGUISHING MEDIA Suitable: Water spray, Carbon dioxide, dry chemical powder, or appropriate foam. FIREFIGHTING Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Specific Hazard(s): SECTION 6 - Accidental Release Measures PROCEDURE(S) OF PERSONAL PRECAUTIONS Exercise appropriate precautions to minimize direct contact with skin or eyes and prevent inhalation of dust. Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 6 of 13

(CONTINUED) - SECTION 6 - Accidental Release Measures PROCEDURE(S) OF PERSONAL PRECAUTIONS Exercise appropriate precautions to minimize direct contact with skin or eyes and prevent inhalation of dust. METHODS FOR CLEANING UP Wash spill site with soap solution. Flush spill area with copious amounts of water. Place in appropriate container. Ventilate area and wash spill site after material pickup is complete. SECTION 7 - Handling & Storage HANDLING User Exposure - Ensure adequate inhalation. Avoid inhalation. - Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure. STORAGE Suitable: Keep container tightly closed. Store between minus 20 and 4 C -20 C - Best if used within 12 months of receipt. See User Guide for additional storage options SECTION 8 - Exposure Controls / PPE ENGINEERING CONTROLS Contains no substances with occupational exposure limit values. Safety shower and eye bath PERSONAL PROTECTIVE EQUIPMENT Respiratory: Use respirators and components tested and approved under appropriate government standards such as (NIOSH) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dust are desired, use type N95 (US) or type (P1) (EN 143) dust masks. Hand: Handle with protective gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Eye: Tightly fitting safety goggles. Face shield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Skin and Body Protection: Complete suit protecting against chemicals, Flame retardant antistatic protective clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Hygiene Measures: Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. GENERAL HYGIENE MEASURES Wash thoroughly before and after handling. Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 7 of 13

SECTION 9 - Physical / Chemical Properties APPEARANCE PHYSICAL STATE: Solution PROPERTY VALUE AT TEMPERATURE OR PRESSURE MP / MP Range Freezing Point Vapor Pressure Vapor Density Saturated Vapor Concentration SG / Density Bulk Density Volatile % VOC Content Water Content Solvent Content Evaporation Rate Viscosity Surface Tension Partition Coefficient Decomposition Temperature Flash Point Explosion Limits Flammability Autoignition Temperature Refractive Index Optical Rotation Miscellaneous Data Solubility = NOT AVAILABLE SECTION 10 - Stability & Reactivity STABILITY Stable: Stable under recommended storage conditions. See SECTION 7 regarding suitable storage. HAZARDOUS DECOMPOSITION PRODUCTS No data available. HAZARDOUS EXOTHERMIC REACTIONS Will not occur. HAZARDOUS POLYMERIZATION Will not occur. Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 8 of 13

SECTION 11 - Toxicological Information ACUTE TOXICITY No data available. IRRITATION AND CORROSION No data available. SENSITISATION No data available. CHRONIC EXPOSURE No data available. ROUTE OF EXPOSURE Skin Contact: May cause skin irritation Skin Absorption: May be harmful if absorbed through the skin. Eye Contact: May cause eye irritation. Inhalation: Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled. Ingestion: May be harmful if swallowed. SIGNS & SYMPTOMS OF EXPOSURE To the best of our knowledge, the chemical, physical, and toxicological properties have NOT been thoroughly investigated. SECTION 12 - Ecological Information No data available. SECTION 13 - Disposal Considerations APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and a scrubber. Observe all federal, state, and local environmental regulations. SECTION 14 - Transportation Information DOT (US) UN- Number: 3316 Class: Proper Shipping Name: Chemical kits or First aid kits Non-Hazardous for Transport: This substance is considered to be non-hazardous for transport. IATA UN- Number: 3316 Class: Proper Shipping Name: Chemical kits or First aid kits Non-Hazardous for Transport: Non-hazardous for air transport. Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 9 of 13

SECTION 15 - Regulatory Information OSHA HAZARDS TSCA STATUS EU ADDITIONAL INFORMATION Substance Name CAS # HAZARD Code R-Phrase S-Phrase (2-Hydroxypropyl)-β-cyclodextrin 128446-35-5 3 1,2-Propanediol 57-55-6 1 1-Butyl-3-methylimidazolium chloride 79917-90-1 T, N 25-36/37/38-51/53 26-45-61 3 1-Ethyl-3-methylimidazolium acetate 143314-17-4 3 4-Aminobutyric acid (GABA) 56-12-2 Xi 36/37/38 26-36 2 5-Aminovaleric acid 660-88-8 22-24/25 3 6-Aminohexanoic acid 60-32-2 Xi 36/37/38 26-36 2 WGK Germany 6-O-α-D-Maltosyl-β-cyclodextrin 104723-60-6 Acetamide 60-35-5 Xn 40 36/37 1 Adipic acid 124-04-9 36/37/38 Ammonium acetate 631-61-8 1 Ammonium chloride 12125-02-9 Xn 22-36 22 1 Ammonium sulfate 7783-20-2 1 Benzamidine hydrochloride 1670-14-0 36/37/38 Betaine monohydrate 590-47-6 1 Cadmium chloride hydrate 654054-66-7 T+, N 45-46-60-61-25-26-48/23/25-50/53 53-45-60-61 3 Calcium chloride dihydrate 10035-04-8 Xi 26 36 1 Cesium chloride 7647-17-8 2 Cholin acetate 14586-35-7 3 Cobalt(II) chloride hexahydrate 7791-13-1 T, N 49-22-42/43-50/53 53-22-45-60-61 3 D-(+)-Trehalose dihydrate 6138-23-4 2 DL-Malic acid ph 7.0 6915-15-7 Xn 22-37/38-41 26-39 3 D-Sorbitol 50-70-4 2 Ethylammonium nitrate 22113-86-6 Xi 36/37/38 24/25/37/39 Ethylene glycol 107-21-1 Xn 22 1 Ethylenediamine dihydrochloride 333-18-6 Xn 22-36/37/38-42/43 22-26-36/37-45 2 Ethylenediaminetetraacetic acid disodium salt dihydrate 6381-92-6 2 Formamide 75-12-7 T 61 53-45 1 Gadolinium(III) chloride hexahydrate 13450-84-5 Xi 36/37/38 26-36 3 Glutaric acid 110-94-1 Xi 36 26 1 Glycerol 56-81-5 1 Glycine 56-40-6 22-24/25 1 Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 10 of 13

(CONTINUED) - SECTION 15 - Regulatory Information EU ADDITIONAL INFORMATION Substance Name CAS # HAZARD Code R-Phrase S-Phrase Gly-gly 556-50-3 Xi 36 26 3 Gly-gly-gly 556-33-2 3 GSH (L-Glutathione reduced) 70-18-8 2 GSSG (L-Glutathione oxidized) 27025-41-8 Xi 36/37/38 26-36 2 Guanidine hydrochloride 50-01-1 Xn 22-36/38 22 2 Hydroxyectoine 165542-15-4 Xi 36/37/38 26-36 1 Hypotaurine 300-84-5 Xi 36/37/38 26-36 3 L-Argininamide dihydrochloride 14975-30-5 T 20/21/22-39/23/24/25 1 L-Arginine 74-79-3 1 L-Arginine ethyl ester dihydrochloride 36589-29-4 3 L-Glutamic acid 56-86-0 1 L-Histidine 71-00-1 1 Lithium chloride 7447-41-8 Xn 22-36/37/38 26-36/37/39 3 Lithium citrate tribasic tetrahydrate 6080-58-6 Xi 36/37/38 26-36 1 Lithium nitrate 7790-69-4 Xi, O 8-36/37/38 22-26-36/37/39 3 L-Proline 147-85-3 1 WGK Germany L-Serine 56-45-1 Magnesium chloride hexahydrate 7791-18-6 1 Magnesium sulfate hydrate 22189-08-8 1 Methyl-β-cyclodextrin 128446-36-6 3 Methyl α-d-glucopyranoside 97-30-3 3 N-Ethylurea 625-52-5 22-24/25 2 N-Methylformamide 123-39-7 T 61-21 53-45 1 N-Methylurea 598-50-5 22 22-36 3 Non Detergent Sulfobetaine 195 (NDSB-195) 160255-06-1 C 34 26-36/37/39-45 3 Non Detergent Sulfobetaine 201 (NDSB-201) 15471-17-7 22-24/25 3 Non Detergent Sulfobetaine 211 (NDSB-211) 38880-58-9 C 34 26-36/37/39-45 Non Detergent Sulfobetaine 221 (NDSB-221) 160788-56-7 C 34 26-36/37/39-45 1 Non Detergent Sulfobetaine 256 (NDSB-256) 81239-45-4 3 Oxalic acid dihydrate 6153-56-6 Xn 21/22 24/25 1 Pentaerythritol ethoxylate (15/4 EO/OH) 30599-15-6 3 Polyethylene glycol 200 25322-68-3 1 Polyethylene glycol 3,350 25322-68-3 1 Polyethylene glycol 8,000 25322-68-3 1 Polyethylene glycol monomethyl ether 1,900 9004-74-4 Polyethylene glycol monomethyl ether 550 9004-74-4 Polyethylene glycol monomethyl ether 750 9004-74-4 Polypropylene glycol P 400 25322-69-4 1 Polyvinylpyrrolidone K 15 9003-39-8 Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 11 of 13

(CONTINUED) - SECTION 15 - Regulatory Information EU ADDITIONAL INFORMATION Substance Name CAS # HAZARD Code R-Phrase S-Phrase WGK Germany Potassium chloride 7447-40-7 22-24/25 Potassium phosphate dibasic 7758-11-4 22-24/25 3 Potassium thiocyanate 333-20-0 Xn 20/21/22-32-52/53 13-61 1 Sodium benzenesulfonate 515-42-4 Xn 22-36/37/38 26 3 Sodium bromide 7647-15-6 1 Sodium chloride 7647-14-5 1 Sodium malonate ph 7.0 141-82-2 Xn 20/22-41 26-36/39 1 Sodium phosphate monobasic monohydrate 10049-21-5 1 Sodium p-toluenesulfonate 657-84-1 Xi 36/37/38 26-36 1 Sodium sulfate decahydrate 7727-73-3 1 Spermidine 124-20-9 C 34 26-36/37/39-45 3 Spermine tetrahydrochloride 306-67-2 Xi 36/38 26-36 3 Succinic acid ph 7.0 110-15-6 Xi 37/38-41 26-36/37/39 1 Sucrose 57-50-1 2 Tacsimate ph 7.0 Taurine 107-35-7 Xi 36/37/38 26-36 2 TCEP hydrochloride 51805-45-9 C 34 26 27 36/37/39 2 Tetraethylammonium bromide 71-91-0 Xi 36/37/38 26-37 3 Trichloroacetic acid 76-03-9 C, N 35-50/53 26-36/37/39-45-60-61 2 Triethylene glycol 112-27-6 Xi 36/37/38 26-36 1 Trimethylamine N-oxide dihydrate 62637-93-8 Xi 36/38 26-36 2 Tryptone 91079-40-2 3 Urea 57-13-6 1 Water Xylitol 87-99-0 2 α-cyclodextrin 10016-20-3 3 β-alanine 107-95-9 3 β-cyclodextrin 7585-39-9 2 = NOT AVAILABLE UNITED STATES REGULATORY INFORMATION SARA LISTED: SARA LISTED: For additional information on toxicity, please refer to SECTION 2. TSCA INVENTORY ITEM: CANADA REGULATORY INFORMATION WHMIS Classification: This product has been classified in accordance with the hazard criteria of the CPR, and the MSDS contains all the information required by the CPR. Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 12 of 13

SECTION 16 - Other Information DISCLAIMER For R&D use only. Not for drug, household, or other use. WARRANTY The above information is believed to be correct but does no purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of this product. Hampton Research Corp., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. License granted to make unlimited paper copies for internal use only. 1991-2012 Hampton Research Corp. Solubility and Stability Screen HT - HR2-072 www.hamptonresearch.com Page 13 of 13