Overview of the Activities of Estonian Pharmacies

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No of inhabitants Overview of the Activities of Estonian Pharmacies Number of Pharmacies There are three types of pharmacies in Estonia: general pharmacies, veterinary pharmacies and hospital pharmacies. Pharmacies may have branch pharmacies and pharmacy-bus as structural units. The licensed general pharmacy can offer the e-pharmacy service. The changes in the total number of pharmacies from 28-28 are shown in following table, which gives the number of pharmacies and their branches at the beginning of the year. Number of pharmacies (incl. branches) in Estonia 28 28 28 29 2 2 22 23 24 25 26 27 28 General pharmacies 59 496 486 477 469 475 478 476 493 49 495 Hospital pharmacies 29 28 26 26 24 25 24 24 24 24 24 Veterinary pharmacies 8 7 7 7 5 4 4 4 4 4 4 *The number of pharmacies (inc. branch pharmacies) as of st of January Activity licences had been issued to 343 general pharmacies which had 52 branch pharmacies at the beginning of 28. The average number of retail pharmacies in Estonia at st of January 27 was one per every 2685 inhabitants. In most counties the number is below average. However, in Tallinn, Narva, Võru County and Harju County the number is above 3 or more residents per pharmacy. The horizontal line illustrates the average in Estonia. The population figures used to calculate the number of people living in each county was obtained from the regional development database of Statistics Estonia. Number of inhabitants per pharmacy in the beginning of 27 in major cities and counties compared to the Estonian average 4 3 5 3 2 5 2 5 5 The number of hospital pharmacies remain the same during last years. There were 24 hospital pharmacies and one of them branch pharmacy in 27. Nine of the hospital pharmacies were located in Harju County, seven of them in Tallinn, three in Ida-Viru County and two in Tartu County. As for other counties there was one hospital pharmacy in each. Valga County and Võru County are the only counties that have no hospital pharmacies. In 23 22 the number of veterinary pharmacies has decreased, the last five years the number of veterinary pharmacies has remained the same. There were four veterinary pharmacies in Estonia in 27: in Tallinn, Tartu, Põlva County and Saare County.

Expenditure in euros Turnover in million euros Turnover of Pharmacies The statistics of pharmacies based on quaterly reports of pharmacies. Since 25 the data are presented all of pharmacies, main and branch pharmacies. Only the turnover of general and veterinary pharmacies includes VAT (value added tax), the turnover of hospital pharmacies without VAT. The total turnover of all pharmacies and their branch pharmacies was 469.3 million euros in 27. The turnover of general pharmacies was 362.6 million euros (77% of total turnover), the turnover of hospital pharmacies was 5.9 million euros (23%) and the turnover of veterinary pharmacies was.77 million euros (.2%) in 27. The proportion of medicines of total turnover in general and hospital pharmacies was 73% and in veterinary pharmacies 47%. Turnover of pharmacies in 28-27 5 45 4 35 3 25 2 5 5 6 96 89 8 78 6 58 6 72 35 363 23 235 235 24 26 28 297 36 28 29 2 2 22 23 24 25 26 27 General pharmacies Hospital pharmacies Veterinary pharmacies The turnover of medicines in general and hospital pharmacies was 34.4 million euros in 27. Dividing the amount by all inhabitants of Estonia the average expenditure on medicines per inhabitant in 27 was 259 euros per year. Expenditure on medicines per inhabitant per year 28-27 3 25 2 5 5 25 259 229 28 23 93 66 7 72 8 97 2 7 78 53 6 36 4 42 42 3 29 3 38 4 43 48 52 54 59 28 29 2 2 22 23 24 25 26 27 Expenditure on medicines In general pharmacies In hospital pharmacies 2

Turnover in million euros Turnover in million euros General Pharmacies In 27 the turnover of general pharmacies was 362.6 million euros, which increased 3.3% compared to previous year. The turnover of medicines of general pharmacies was 263 million euros in 27. The turnover of medicines includes sales of non-prescription medicines, prescription medicines and veterinary medicines. The turnover of non-prescription medicines was 55.7 million euros. The turnover of prescription medicines can in turn be divided into turnover of medicines dispensed on the basis of prescriptions the Estonian Health Insurance Fund (EHIF) compensates for or not. The turnover of medicines dispensed on the basis of prescriptions with discounts is the highest (9 million euros) with approximately 92% of the total turnover from prescription medicines. The turnover of veterinary medicines in general pharmacies is relatively modest and remained in.78 million euros in 27. The turnover of the other goods was 99.7 million euros which increased 8.8% in 27 compared to the 26. Turnover of general pharmacies in 28-27 4 35 3 25 2 5 5 83 74 68 58 48 47 46 5 2 2 3 4 36 36 36 37 4 43 46 49 33 4 43 4 52 56 64 7 92 53 56 6 7 9 9 28 29 2 2 22 23 24 25 26 27 Reimbursed medicines Non-reimbursed medicines Non-prescription medicines Other goods The cost of prescription medicines reimbursed by EHIF divided as follows in 27: ca. 3% paid by the patient and ca. 7% paid by the EHIF. The average cost of a prescription reimbursed by EHIF is influenced by the quantity of reimbursed medicines dispensed as well as the choice of specific discounted medicines, i.e. whether the chosen medicinal product with the same active ingredient is the more expensive or a cheaper option. The average cost of a reimbursed medicine in 27 was 22.4 euros. 2 8 6 4 2 8 6 4 2 Turnover of reimbursed medicines in general pharmacies 28-27 5 5 5 48 5 5 52 55 83 89 92 93 6 2 5 56 58 34 32 28 29 2 2 22 23 24 25 26 27 Reimbursed by EHIF Patients co-payment 3

Turnover in euros The average turnover of general pharmacies was.75 million euros and the average turnover of medicines.55 million euros. When we look at the average turnover of general pharmacies in major cities and counties, shows that the average turnover is strongly affected by the sales of Tallinn, Tartu, Pärnu and Narva pharmacies. 2 Average turnover of general pharmacies in major cities and counties 27 8 6 4 2 Average total turnover Estonian average total turnover Average turnover of medicines Estonian average turnover of medicines A quarter of all general pharmacies are located in Tallinn. Almost 73% of all general pharmacies and their branch pharmacies are located in towns and cities. Pharmacies by counties..28 City/ County Main pharmacy Main pharmacy in the city Main pharmacy in rural areas Branch pharmacy Branch pharmacy in the city Branch pharmacy in rural areas Harju County 24 3 26 7 9 Tallinn 2 2 8 8 Hiiu County 3 2 2 2 Ida-Viru County 9 8 3 3 Narva 8 8 9 9 Jõgeva County 8 3 2 Järva County 8 3 2 2 Lääne County 5 4 4 3 Lääne-Viru County 2 6 5 7 3 4 Põlva County 6 5 7 3 4 Pärnu 6 6 4 4 Pärnu County 2 8 8 7 Rapla County 8 2 6 5 2 3 Saare County 8 3 4 3 Tartu 3 3 3 3 Tartu County 3 4 9 4 3 Valga County 8 2 4 2 2 Viljandi County 3 3 8 2 6 Võru County 7 4 2 Total 343 285 58 52 84 68 Grand total 495 4

The most of general pharmacies located in towns and cities. The turnover of general pharmacies located in cities was 89% of total turnover of all general pharmacies. Only % of medicines has sold in general pharmacies in rural areas. General pharmacies in 27 The turnover of medicines in the cities and rural areas in 27 25% 2% 9% 9% 75% 7% No of general pharmacies in the cities No of general pharmacies in rural areas Non-prescription medicines in the cities Prescription medicines in the cities Non-prescription medicines in rural areas Prescription medicines in rural areas At the same time the distribution of turnover of general pharmacies in cities and general pharmacies in rural areas is similar. The turnover of prescription medicines was the highest, 57% in general pharmacies located in cities and 56% in general pharmacies located in rural areas. The turnover of non-prescription medicines was 5% and 6%. The turnover of the other goods was the same 28% in general pharmacies located in cities and in rural areas. The turnover of general pharmacies in the cities The turnover of general pharmacies in the rural areas 28% 5% 28% 6% 57% 56% Non-prescription medicines in the cities Prescription medicines in the cities Other goods in the cities Non-prescription medicines in rural areas Prescription medicines in rural areas Other goods in rural areas 5

Expenditure in euros The average amount spent by an inhabitant of Estonia on medicines in 27 was 8.2 euros per month, almost 99 euros per year. Compared to 26 the expenditure on non-prescription medicines increased 4.5% and the expenditure on prescription medicines increased 3.5%. Expenditure on medicines per inhabitant per month in 28-27 6 5 4 3 3,9 3,9 3,83 3,73 3,82 3,92 2,69 2,5 2,25 2,26 2,22 2,3 4, 2,89 4,35 3, 4,55 3,37 4,7 3,52 2 28 29 2 2 22 23 24 25 26 27 Expenditure on prescription medicines Expenditure on non-prescription medicines More than million prescriptions were handled by general pharmacies in 27. The largest proportion was medicines dispensed on the basis of prescriptions reimbursed by EHIF (8.5 million prescriptions). The number of prescriptions without discounts was ca..5 million, while the number of EU prescriptions was slightly over three thousand and seven hundred and the number of prescriptions for medicines prepared ex tempore remained nearly 4 thousand. The number of prescriptions of medicines for veterinary purposes was nineteen thousand. Prescriptions handled by general pharmacies in 27 4,8%,6%,9%,4% 84,5%,4% Prescriptions reimbursed by EHIF Non-reimbursed prescriptions Ex tempore prescriptions Veterinary prescriptions EU prescriptions 6

No of medicines 4% of main pharmacies (3 general pharmacies) prepared medicines ex tempore or officinal formulae or divided them up into smaller packages in 27. 2% of main pharmacies prepared medicines as officinal formulae, 34% prepared medicines ex tempore and % of main pharmacies divided medicines up into smaller packages. 64% of main pharmacies did not prepare or divide up any medicines. Almost 3 thousand medicine packages were prepared in general pharmacies in 27, more than 48 thousand of which were prepared ex tempore. The number of medicines prepared ex tempore was highest in Tallinn an Tartu comprising 67% of all medicines prepared ex tempore in general pharmacies in 27. The number of medicines prepared as officinal formulae was highest in Tartu comprising 42% of all medicines prepared as officinal formulae in general pharmacies in 27. There were three counties (Rapla, Tartu and Viljandi County) where no one of pharmacies did not prepared medicines as officinal formulae. The number of medicines divided up into smaller packages was highest in Tallinn. 6 4 2 8 6 4 2 Medicines prepared in general pharmacies in 28-27 28 29 2 2 22 23 24 25 26 27 Prepared as officinal formulae Prepared ex tempore Divided up into smaller packages 2-5 employees usually work in one main pharmacy or branch pharmacy. The number of general pharmacies with more than employees is highest in Tallinn, while the number of general pharmacies with one employee is highest in Tartu County. 39% of all people working in general pharmacies are employed part-time. The proportion of pharmacists is highest and comprise 4% of all general pharmacy employees in Estonia, pharmacist assistants comprise 33% and other employees 26%. General pharmacies divided by the number of employees in 27 2 27 6 Pharmacies with employee Pharmacies with 2-5 employees Pharmacies with 6-9 employees Pharmacies with and more employees 33 7

Turnover in million euros Hospital Pharmacies The total turnover of hospital pharmacies in 27 was 5.9 million euros, of this the turnover of medicines comprised 77.4 million euros (73%). The turnover of hospital pharmacies is calculated without VAT. Turnover of hospital pharmacies in 28-27 2 8 6 4 2 2 2 2 4 38 4 2 24 24 5 54 57 29 28 26 64 68 7 28 77 28 29 2 2 22 23 24 25 26 27 Medicines Other goods The turnover of hospital pharmacies is very versatile. The annual turnover of fourteen hospital pharmacies was less than one million euros. There are six medium-sized hospital pharmacies whose turnover remained between one and five million euros, and there are also four large hospital pharmacies in Estonia whose turnover in 27 exceeded five million euros. In total, the four largest pharmacies comprised 76% of the total turnover of hospital pharmacies. This means that the four largest pharmacies also have a very strong impact on the average annual turnover of hospital pharmacies, which in 27 was 4.4 million euros. When we look at the remaining pharmacies separately from the four largest, we see that the average annual turnover is considerably smaller.2 million euros. The employees in hospital pharmacies are mostly pharmacists. 73 pharmacists, 38 pharmacist assistants and 35 other employees worked in hospital pharmacies at the end of 27. Up to five people work in medium-sized hospital pharmacies and only the largest ones employ more than five people. Hospital pharmacies divided by the number of employees in 27 3 5 Hospital pharmacies with employee 4 Hospital pharmacies with 2-5 employees Hospital pharmacies with 6-9 employees Hospital pharmacies with and more employees 2 8

Number of prescriptions Turnover in thousand euros Veterinary Pharmacies The number of veterinary pharmacies and the total turnover of veterinary pharmacies has decreased until 23. The last five years the number of veterinary pharmacies has remained the same and the turnover has started to increase. There were four veterinary pharmacies operating in Estonia in 27 and the total turnover was.77 million euros and the proportion of medicines was 47%. The veterinarians may purchase veterinary medicines directly from wholesalers. In 27 wholesalers dispensed around 87% of veterinary medicines directly to operating veterinarians or veterinarians representing agricultural undertakings, 6% to veterinary pharmacies, 5% to general pharmacies and 2% to other institutions. Turnover of veterinary pharmacies in 28-27 4 2 248 8 6 4 2 324 73 22 22 37 32 639 66 5 8 244 253 55 524 99 7 94 85 224 22 253 239 277 386 43 388 43 4 28 29 2 2 22 23 24 25 26 27 Other goods Prescription medicines Non-prescription medicines Veterinary pharmacies dispense prescription medicines on the basis of order forms and prescriptions. The number of prescriptions handled by veterinary pharmacies has decreased by 76% in the past ten years. Number of prescriptions handled in veterinary pharmacies in 28-27 4 3 5 3 2 5 2 5 5 3 523 3 576 2 923 496 48 937 92 935 887 845 28 29 2 2 22 23 24 25 26 27 In 27 seven veterinarians worked in four veterinary pharmacies. 9