Evolution of the individualized treatment landscape for advanced NSCLC

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IASLC Asia Pacific Lung Cancer Conference (APLCC 2016) 13-15 May 2016, Chiang Mai, Thailand Evolution of the individualized treatment landscape for advanced NSCLC Chaired by Tony Mok Empress Grand Hall, 3rd floor, Empress Convention Center Friday 13th May 11:00 12:00 This program is made possible thanks to independent educational sponsorship from Eli Lilly and Company

Contents 3 Learning objectives 3 Program 4 Welcome message 5 Faculty biographies Tony Mok 6 Faculty biographies Ross Soo 7 Faculty biographies Giorgio Scagliotti 8 Symposium information 9 Notes Evolution of the individualized treatment landscape for advanced NSCLC IASLC Asia Pacific Lung Cancer Conference (APLCC 2016)

Learning objectives After attending this symposium, learners will be able to: Assess the new treatment paradigms for non-mutated advanced and metastatic non-squamous NSCLC, and explain how to best apply them to individualized patient care in their daily practice Describe the rapidly expanding and complex range of treatment options for advanced and metastatic squamous NSCLC, and explain how to best apply them to individualized patient care in their daily practice Program 11:00 11:05 Welcome and introduction Tony Mok (Hong Kong) 11:05 11:30 How best to manage patients with non-squamous NSCLC without EGFR/ALK mutations Ross Soo (Singapore) 11:30 11:55 Therapeutic options for patients with advanced squamous NSCLC Giorgio Scagliotti (Italy) 11:55 12:00 Closing remarks Tony Mok (Hong Kong) Springer Healthcare IME 3

Welcome message Dear Colleagues, Welcome to Thailand and thank you for attending this satellite symposium entitled Evolution of the individualized treatment landscape for advanced NSCLC at the IASLC Asia Pacific Lung Cancer Conference (APLCC 2016). Chiang Mai, Thailand s northern capital, provides a historic and culturally vibrant host city for this conference that brings together a unique community of medical professionals from across the Asia Pacific region. The aim of this symposium is to facilitate the management of squamous and nonsquamous NSCLC, and the implementation of new discoveries in clinical practice. It will also address the challenges facing clinicians in the Asia Pacific region in an increasingly complex treatment landscape. During this session, the expert Faculty will guide us through this complexity by placing the latest developments in advanced NSCLC into the context of treatment. They will provide their insights into how we can use our biological knowledge not only to improve treatment pathways, but also on how to maximize treatment outcomes by understanding different approaches. We hope that you find this symposium educational and that it will further your understanding of this evolving field. Accordingly, we aim to provide maximum interaction and discourse between Faculty and audience so that we may work together to optimize patient outcomes. We would be grateful if you would kindly provide your feedback by completing the evaluation form provided with this booklet. Yours faithfully, Tony Mok Tony Mok Chair Evolution of the individualized treatment landscape for advanced NSCLC IASLC Asia Pacific Lung Cancer Conference (APLCC 2016)

Faculty biographies Tony Mok (Symposium Chair) The Chinese University of Hong Kong, Hong Kong Tony Mok was trained at the University of Alberta and subsequently completed a fellowship in medical oncology at the Princess Margaret Hospital. After working as a community oncologist in Toronto for seven years, he returned to Hong Kong in 1996 to pursue an academic career. Professor Mok is the Li Shu Fan Medical Foundation Named Professor of Clinical Oncology and Chairman of Clinical Oncology at The Chinese University of Hong Kong. His main research interest focuses on biomarker and molecular-targeted therapy in lung cancer. He co-founded the Lung Cancer Research Group, and has led a number of important multinational clinical trials, which include the IPASS (IRESSA Pan-Asia Study), a landmark study that established the role of first-line gefitinib in patients with EGFR mutations. Professor Mok has contributed to over 200 articles in international peer-reviewed journals, including The New England Journal of Medicine, Science, The Lancet and Journal of Clinical Oncology, and has also contributed to multiple editorials and textbooks. He is also active and experienced in serving academic societies. He is the Past President of the International Association for the Study of Lung Cancer (IASLC), Past Chair of the American Society of Clinical Oncology (ASCO) International Affairs Committee, a member of the ASCO Publications Committee and Vice Secretary of the Chinese Society of Clinical Oncology (CSCO). He is closely affiliated with the oncology community in China and has received an Honorary Professorship at Guang Dong Province People s Hospital, Guest Professorship at Peking University School of Oncology, Visiting Professorship at Shanghai Jiao Tong University and West China School of Medicine/West China Hospital, Sichuan University. He is an Editor on thoracic oncology for the Journal of Clinical Oncology. He has also authored eight books in Chinese and hosted three television series in Hong Kong. Springer Healthcare IME 5

Ross Soo National University Cancer Institute, Singapore Ross Soo is a Senior Consultant for the Department of Hematology Oncology at the National University Cancer Institute, Singapore (NCIS), where he specializes in lung cancer and head and neck cancer, and leads the Lung Tumor Group. Additionally, he is an Adjunct Principal Investigator for the Cancer Science Institute of Singapore and belongs to several professional societies and associations, such as the American Society of Clinical Oncology (ASCO), the International Association for the Study of Lung Cancer (IASLC), and the Singapore Society of Oncology. Dr Soo received his medical degree from Monash University and underwent specialist training in Melbourne and Sydney. He subsequently became a fellow of the Royal Australasian College of Physicians and the Academy of Medicine in Singapore. Dr Soo maintains an international presence in oncology, as he has been invited to speak and present his research findings at many international meetings and has published more than 90 papers in scientific journals including Cell, Nature Medicine, Cancer Research and Science Translational Medicine. Dr Soo s research interests are in lung cancer and nasopharyngeal cancer. Dr Soo also sits on various committees, including the IASLC Communications Committee, National Healthcare Group Domain-Specific Ethics Review Board, the Ministry of Health Drug Advisory Committee, and the Medical Oncology Specialist Training Committee. Evolution of the individualized treatment landscape for advanced NSCLC IASLC Asia Pacific Lung Cancer Conference (APLCC 2016)

Giorgio Scagliotti University of Torino, Italy Giorgio Scagliotti is currently Head of the Department of Oncology and Professor of Oncology at the University of Torino. He is also Chief of the Medical Oncology Division at the S. Luigi Hospital. He earned his medical degree and completed his postgraduate training in Respiratory Medicine, Internal Medicine and Medical Oncology at the University of Torino. Professor Scagliotti is a member of several scientific societies, including the Italian Society of Respiratory Medicine, the European Respiratory Society, the American Society of Clinical Oncology (ASCO), and the International Association for the Study of Lung Cancer (IASLC). From 2003 2007 he was an Executive Board member of the IASLC. He is also Associate Editor for the Journal of Thoracic Oncology, International Editor for Clinical Lung Cancer and the author or co-author of more than 280 publications in peer-reviewed journals. Alongside this, he is the International Editor of the 4th Edition of Lung Cancer: Principles and Practice and co-editor of the IASLC textbook Multidisciplinary Approach to Thoracic Oncology. Springer Healthcare IME 7

Symposium information Organizers This educational activity has been planned and independently implemented by Springer Healthcare IME. Springer Healthcare IME is the Independent Medical Education group of the Springer Nature global publishing group. Filming and photography Springer Healthcare IME may film or take photographs at the symposium that may be used in publicity and marketing materials. Your attendance at the meeting may mean you are featured in such photographs and films. Unless you notify a member of the Springer Healthcare IME team of your objection to this your consent will be implied. Educational sponsorship This program is made possible thanks to independent educational sponsorship from Eli Lilly and Company. Evolution of the individualized treatment landscape for advanced NSCLC IASLC Asia Pacific Lung Cancer Conference (APLCC 2016)

Notes Springer Healthcare IME 9

Notes Evolution of the individualized treatment landscape for advanced NSCLC IASLC Asia Pacific Lung Cancer Conference (APLCC 2016)

Notes Springer Healthcare IME 11

This program is made possible thanks to independent educational sponsorship from Eli Lilly and Company