PROGRAM. 07 MARCH 16 Sepsis 3.0

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PROGRAM 07 MARCH 16 Sepsis 3.0 09h00-10h30 Sepsis 3.0 Chairmen: Jorge Pimentel Júlio Nóbrega - Our evolving understanding of sepsis - Infection in the ICU: an EPIC issue - Death despite adequate antibiotics 10h30-11h00 Coffee-Break 11h00-12h00 Opening session Chairman: Germano do Carmo - The Infection and Sepsis Group, 20 years later - Dear SIRS, I just knew there was something wrong about you 12h00-13h15 Fluids and sepsis Chairmen: Francisco Esteves Paula Castelões - Fluid balance and clinically relevant outcomes - Timing of vasopressors: how soon is too soon? - Are balanced solutions the way to go? 13h15-13h45 MSD Symposium - Najy Alsayed 13h45-14h30 Lunch 14h30-15h30 Septic shock Chairmen: Paulo Mergulhão Paula Coutinho - Early goal directed therapy is still a valid concept: pro - con debate - Pro: Jukka Takala - Con: Anand Kumar 15h30-16h00 16h00 16h00-16h30 16h30-17h45 17h45-18h15 Early identification remains the key issue. Chairman: Rui Araújo - Marin Kollef Poster Presentation Coffee-Break Heart, vasopressors and inotropes Chairmen: João Ribeiro TBA - Epinephrin or norepinephrine: how to choose wisely - Dobutamine: never without an echocardiogram? - Hyperdynamic vs hypodynamic septic shock Jukka Takala Jean Louis Vincent Marin Kollef João Jaime Sá Jean Louis Vincent Rui Moreno Anand Kumar Michel Slama Miguel Tavares Michel Slama Jukka Takala Optimizing therapy in severe intra-abdominal infection. Chairmen: John Preto Carlos Alves - Anand Kumar

PROGRAM 08 MARCH 16 A new twist on the issue of tissue: focus on foci! 09h00-10h15 10h15-10h45 10h45 10h45-11h15 11h15-12h30 12h30-13h00 13h00-14h15 14h15-15h30 15h30-16h00 16h00 16h00-16h30 16h30-18h00 CAP Chairmen: José Manuel Pereira Luís Telo - Maximizing the efficacy of antibiotic therapy - Immunomodulation in CAP - MDR agents: risk factors and therapeutic strategies De-escalation: Still a believer Chairman: Paulo André Fernandes - José Artur Paiva Poster Presentation Coffee-Break Legionella infection Chairmen: António Sarmento TBA - What is the best AB option? - ECMO for severe Legionella pneumonia - The Portuguese Legionella outbreak: lessons learned Worldwide HAP/VAP consensus guidelines Chairman: Filipe Froes - Antoni Torres Lunch Fungal infection Chairmen: José Neves Cidália Pina-Vaz - Are biomarkers useful to guide therapy? - Aspergillus in respiratory tract of critically ill patients: Dos and don ts. - Role of TDM and de-escalation in antifungal therapy. João G. Pereira Antoni Torres Marin Kollef Filipe Froes Roberto Roncon Paula Rosa Jesús Guinea Gennaro de Pascale Jesús Guinea Innovative thinking Chairman: Rui Moreno - Cerebral monitoring in sepsis. Celeste Dias Poster Presentation Coffee-break New antimicrobials and strategies Chairmen: João Pedro Baptista Rui Veiga - Upcoming options for resistant gram-negative pathogens. - Beta-lactam treatment should be guided by TDM. - Antibiotic dosing during extra-corporeal treatment. Marin Kollef Gennaro De Pascale Patrick Honore 1

PROGRAM 09 MARCH 16 Coming Issues 09h00-09h30 09h30-10h30 10h30-11h00 11h00-12h00 12h00-13h00 13h00-13h30 Innovative thinking Chairmen: TBA - Rapid assessment of resistance patterns and mechanisms. Cidália Pina-Vaz New Portuguese guidelines Chairmen: Helena Ramos Antero Fernandes - Portuguese Sepsis fast-track. - Preventing infection: Novel strategies to tackle the problem. Coffee-break Sepsis in critically ill cancer patients Chairmen: Cristina Sarmento M.J. Bouw - Ethics and guidelines. - Oncology patients coming into the ED with infection. - Should we admit these patients to the ICU? Triage, boundaries and outcomes. Extra-corporeal treatment Chairmen: João Gouveia Armindo Ramos - Polymixin hemoperfusion in gram negative sepsis. - Cytokine removal in early septic shock: what is the evidence? - Markers of prognosis in sepsis induced AKI. Sérgio Gaião João Ribeiro Paulo André Fernandes Paulo Maia Paulo Mergulhão Filomena Faria Gennaro De Pascale Patrick Honore Sérgio Gaião GIS/Astellas scholarship on mycology clinical research 2

Grupo de Infecção e Sepsis thanks Gilead for the unrestricted support of the Fungal Infection Round table.

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