PRODUCT TECHNICAL DOSSIER L-HISTIDINE HCl Product Code: P08100 Raw Material Full Name: L-Histidine Raw Material Full Botanical/Chemical/Latin/Trade Name/Synonyms: (S)-2-Amino-1H-imidazole-4-propionic acid monohydrochloride monohydrate This material is Food Grade Assay: 98.5 101.0% Identification: Conforms to the EP CAS Number: 5934-29-2 Molecular Formula for the raw material: C 6 H 9 N 3 O 2 H 2 O Average Molecular weight: 209.63 g/mol Solubility in Water: 16.8 (20 o C); 29.6 (40 o C);47.5 (60 o C) Solubility in Alcohol: This product is practically insoluble in alcohol. Particle Size: 20 Mesh
Percentage passed through: 90% pass through ph: 3.0-5.0 Loss on Drying: 7%-10% Residue on Ignition (Sulphated): Max 0.10% Sulphates (SO 4 ): Max 0.030% Chloride (Cl): 16.66% to 17.08% Specific Rotation [a] 20 D: +9.2-10.6 State of Solution: Clear & colourless Ammonium (NH 4 ): Max 0.02% Other Amino Acids: Conforms Country of Origin: China Country of Origin of the Manufacture: China Base Source/Start Material: Duck Feathers
What is the extraction/processing used? What solvents are used and at what ratio s? Hydrolysis Material is: 100% Compound Ingredients: None Shelf Life from Date of Manufacture: 2 Years Storage Conditions: Store under room temperature, keep container sealed and protect from sunlight Appearance: Crystal/ Crystalline Powder Colour: White/Off White Flavour/Taste: Slightly acid and bitter taste. Aroma: Characteristic Metals Heavy Metals: Max 10ppm Iron (Fe): Max 10ppm Arsenic (As): Max 1pm Lead (Pb): Max 3ppm
Mercury (Hg): Max 0.1ppm Cadmium (Cd): Max 1ppm Microbiology Total Plate Count: Max 1,000cfu/g Coliforms: Negative E Coli: Negative Yeast & Moulds: Max 100cfu/g Salmonella spp: Negative Pharmacopeia Standard Used: EP There are no nuts in this recipe and are no nuts on site, however we cannot guarantee that the raw materials entering the site are nut free.
INTOLERANCE DATA If No please give details Free from All Animal Products (Beef, Pork, Poultry or other) NO Duck Feathers Free from Bovine Products or Derivatives by using hormones to increase milk yield in cows Free from Bone Meal Free from Peanuts and Peanut Derivatives (including possible cross contamination) Free from other Nut and Nut Derivatives Free from Nut Derived Oil Free from Sesame Seeds and Sesame Seed Derivatives Free from Poppy Seeds and Poppy Seed Derivatives Free from Sunflower Seeds and Sunflower Seeds Derivatives Free from other Seeds and Seed Derivatives Free from Milk and Milk Derivatives (including lactose) Free from Egg and Egg Derivatives Free from Cereals containing Gluten (wheat / rye / oats / barley/ spelt/ kamut or their hybridised strains) and Derivatives Free from Soya and Soya Derivatives Free from Maize and Maize Derivatives Free from Corn and Corn Derivatives Free from Lupin and Lupin Derivatives Free from Yeast and Yeast Derivatives Free from Cotton Seeds (Flour) and Cotton Seed Derivatives Free from Rice and Rice Derivatives Free from Mustard and Mustard Derivatives Free from Celery or Celery Derivatives Free from Celeriac or Celeriac Derivatives Free from Fruit and Fruit Derivatives Free from Vegetable and Vegetable Derivatives Free from Carrot and Carrot Derivatives Free from Legumes / Pulses Free from Fish and Fish Derivatives Free from Crustaceans / Molluscs and their Derivatives Free from Additives Free from Added Salt Free from Added Sugar Free from Antioxidants Free from Artificial Glutamates Free from Aspartame Free from Azo and Coal Tar Dyes Free from Benzoates (E210 / E219) Free from BHA / BHT (E320 / E321) Free from Caffeine Free from Cinnamon Free from Cocoa Free from Colours (Artificial / Nature Identical / Natural / Smoked) Free from Dextrose Free from Dioxins Free from Ethanol
INTOLERANCE DATA If No please give details Free from Ethylene Oxide Free from Flavourings (Artificial / Nature Identical / Natural / Smoked) Free from Garlic Free from Gelatine Free from Glutamates (E620 to E625) Free from Histamine Free from Hickory Free from Honey Free from Lactose Free from Latex Free from MSG (Added and Naturally Occurring E621) Free from Nucleotides (E627, E630, E631, E635) Free from Polyols Free from Preservatives Free from Starch Products (Including Maltodextrin) Free from Sorbic Acid (E200, E203) Free from Sulphur Dioxide and Sulphites at levels above 10mg/kg or 10mg/litre expressed as SO 2 Free from Sulphites (E220, E228) Free from Sweeteners Free from Vannillin Suitable for Diabetics Suitable for Coeliacs Suitable for Ovo-Lacto Vegetarians NO Duck Feathers Suitable for Vegans NO Duck Feathers Kosher Certified NO Not Certified Halal Certified NO Not Certified
CONFIRMATION OF BSE/TSE STATUS This is to certify that this product complies with all relevant current UK and EU Legislative requirements in regard to Transmissible Spongiform Encephalopathies (TSE) and Bovine Spongiform Encephalopathy (BSE) for human food, and so is free of TSE/BSE. This is also to certify that, during the course of their manufacture, the above-mentioned product did not come into contact with any materials, which could be derived from TSE/BSE risk materials. CONFIRMATION OF GM STATUS This is to certify that this product is not manufactured from GM raw materials and is therefore not subject to labelling under regulations 1829/2003/EC and 1830/2003/EC. CONFIRMATION OF NON IRRADIATION STATUS This is to certify that this product, whole or in part, has not been subjected to Ionising Radiation as per European Directives 1999/2/EC and 1000/3/EC. CONFIRMATION OF NANDROLONE STATUS This is to certify that this product, whole or in part, has not come into contact with Nandrolone or any of its precursors in any way. CONFIRMATION OF IOC PRODUCT STATUS This is to certify that this product, whole or in part, has not come into contact with any product/s, which is banned by the IOC (International Olympics Committee). CONFIRMATION OF ANIMAL TESTING STATUS This is to certify that all the products sold by Cambridge Commodities have not been tested on animals in any part of its manufacture in accordance with regulation 86/609/EEC. CONFIRMATION OF PESTICIDES STATUS This is to certify that the above-mentioned product complies with the regulation (EC) No.396/2005 of 23 rd February 2005 and commission Regulation (EU) No. 559/2011 of 7 th June 2011 amending annexes II and III of the above Regulation.
Product Flow Chart Duck Feathers Mother liquid Extraction Desalination Adsorption Decolor Ion Exchange Concentrate, crystallize Centrifuge, drying Finished product
MATERIAL SAFETY DATA SHEET Section 1 Description Product Name: Product Code: Supplier: L-HISTIDINE MONOHYDROCHLORIDE P08100 Cambridge Commodities Limited 78 Lancaster Way, Ely, Cambridgeshire, CB6 3NW. Tel: 01353 667258. Email: QC@c-c-l.com Section 2 Ingredients/Identity Information Components % in Product CAS Number Formula L-Histidine 100 5934 29-2 C 6 H 9 N 3 O 2 H 2 O Section 3 Possible Hazards Eye Contact: Skin Contact: Inhalation: Ingestion: No adverse effects expected but dust may cause mechanical irritation. No adverse effects expected. May cause mild irritation and redness. Not expected to be a health hazard. Can cause breathing difficulty if inhaled in large amounts. Not expected to be a health hazard via ingestion. Large amounts may produce gastric upset. Section 4 Emergency and First Aid Procedures Eyes Skin Swallowing Inhalation If symptoms develop, move individual away from exposure and into fresh air. Rinse with plenty of water for at least 15 minutes while holding eyelids apart. Seek medical attention if irritation persists. Wash affected area with soap and copious amounts of water. If irritation persists, seek medical attention. Wash out mouth and drink water if conscious. Never give anything by mouth to an unconscious person. Seek medical attention if feeling unwell. Remove to fresh air. Rinse mouth with water. If breathing is difficult, administer oxygen and seek medical attention.
Section 5 Fire and Hazard Data Fire and Explosion Hazards Extinguishing Media Flammability Fire Fighting Instructions Not expected to be a fire hazard. Water spray Non-Flammable Wear a self-contained breathing apparatus with a full-face piece operated in the positive pressure demand mode. Use chemical resistant personal protective equipment. Equipment should be thoroughly decontaminated after use. Section 6 Accidental release measures Procedures of personal precaution Use personal protection. See section 8 Environmental precautions Cleaning up Methods Avoid run-off into waterways and sewers. Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete. Section 7 Precautions for Safe Handling and Storage Handling Avoid creating dust. Avoid contact with eyes, skin and clothing, avoid prolonged or repeated exposure. Storage Keep containers tightly closed in a cool and dry place. Avoid humidity sunlight and high temperatures. Section 8 Control Methods/Personal Protection Hand/Body Protection Eye Protection Avoid contact and prolonged or repeated exposure. Wear resistant gloves such as rubber. Wash thoroughly after handling. Protective clothing recommended. Wear safety glasses in compliance with OSHA regulations.
Section 9 Physical and Chemical Properties Physical state Crystals/Crystalline Powder Colour White /Off White Melting point 287 o C (Decomposes) Solubility 3.84 g/100ml H 2 O (20 C) ph 7.0 8.5 (1.0g in 50 ml of H 2 O) Section 10 Stability and Reactivity Chemical Stability Stable under conditions mentioned in section 7 Section 11 Toxicological Information Acute Toxicity Data LD50 (ORAL RAT): >15 g/kg Carcinogenicity NTP: NO IARC: NO ZLIST: NO See Registry of Toxic Effects of Chemical Substances (RTECS) for complete information Skin Contact Eye Contact Inhalation Ingestion Chronic Exposure Section 12 Ecological Information May cause skin irritation Causes eye irritation May be harmful if inhaled, material is an irritant to mucous membranes and upper respiratory tract. Harmful if swallowed in large amounts Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting No Data Available Section 13 Disposal Considerations No Data Available
Section 14 Transport Information Not a DOT controlled substance Section 15 Regulatory Information No Data Available Section 16 Other Information This advice is given by Cambridge Commodities Ltd who accept no legal liability for it. The information contained herein is based on the present state of our knowledge and is intended to describe our products from the point of view of safety requirements. It should not therefore be construed as guaranteeing specific properties. Individuals working with chemicals should consider all chemicals to be potentially hazardous even if their individual hazards may be uncharacterised or unknown. We confirm that the information above is sourced from the original manufacturers/suppliers Material Safety Data Sheet. Version No: 4