Strategies to Manage The Opioid Crisis

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Strategies to Manage The Opioid Crisis Matt Feehery, LCDC Senior Vice President & CEO PaRC (Prevention & Recovery Center) Behavioral Health Services February 1, 2018

A Pill for Your Pain But my doctor prescribed it, so it can t be bad. We started on this whole thing because we were on a mission to help people in pain, states Dr. Jane C. Ballantyne, a Seattle pain expert. But the long-term outcomes for many of these patients are appalling, and it is ending up destroying lives. The use, overuse and misuse of prescription opioids continues to rise. (Source: New York Times 2012)

A Pill for Your Pain Rx Pain Killers: $57 Billion Global Annual Sales 1 in 12 US doctors receive payments from opioid makers All in all, more than 68,000 physicians received more than $46 million between 2013 and 2015 in non-research payments from drugmakers that create pain-killing opioids or medication-assisted opioid treatments like buprenorphine, according to a study published in the American Journal of Public Health. Although researchers found the doctors received an average payment of $15, the top 1 percent of physicians received 82 percent of all opioid drugmaker payments. (Source: IMS Health, 2015) (Modern Healthcare, August 2017)

A Pill for Your Pain Opioid Makers Sued for Stoking Addiction Ohio filed suit against five drug companies, alleging they fueled the opioid addiction crisis by misrepresenting the addictive risks of their painkillers. South Carolina filed suit against Purdue Pharma LP, which manufactures OxyContin. New Hampshire, Mississippi, Missouri, Oklahoma and West Virginia have filed similar suits. Cities of Cincinnati and Birmingham filed public nuisance suits against wholesale drug distributors for dumping millions of dollars worth of prescription opioids into the communities. We are obligated to take action as South Carolinians fall victim to Purdue s deceptive marketing. South Carolina Attorney General Alan Wilson The companies were dishonest with doctors and the public about their painkillers risks. Ohio Attorney General Mike DeWine (Source: Wall Street Journal, June 1 & August 16, 2017)

Opioid Overuse, Misuse and Addiction: A Public Health Crisis Drug overdose is the leading cause of accidental death in the US 47,055 lethal drug overdoses in 2014 52,400 in 2015 (33,000 involved opioids) 63,600 in 2016 (42,200 involved opioids) 67,000 in 2017 (estimated) Over 65% of accidental overdose deaths are due to opioids (prescription pain relievers and heroin) While cumulative pain levels remained constant among Americans, sales of prescription pain relievers in 2010 were four times those in 1999. In 2012, 259 million prescriptions were written for opioids, which is more than enough to give every American adult their own bottle of pills. (This upward trend is now decreasing.) Four in five (80%) new heroin users started out misusing prescription painkillers. 94% of respondents in a 2014 survey of people in treatment for opioid addiction said they chose to use heroin because prescription opioids were far more expensive and harder to obtain. (Source: ASAM Opioid Addiction 2016 Facts and Figures, NIDA, SAMHSA)

SAMHSA NSDUH Data 2011-2013, CDC Infographic

The Opioid Crisis On an average day More than 650,000 opioid prescriptions are dispensed1 3,900 people initiate nonmedical use of prescription opioids2 580 people initiate heroin use2 91 people die from an opioidrelated overdose*3 Economic Impact 55 billion in health and social costs related to prescription opioid abuse each year1 20 billion in emergency department and inpatient care for opioid poisonings2 Source: 1. CDC, MMWR, 2015; 64;1-5; 2. CDC Vital Signs, 60(43);1487-1492; Pain Med. 2011;12(4):657-67.1 2013;14(10):1534-47.2 *Opioid-related overdoses include those involving prescription opioids and illicit opioids such as heroin Source: IMS Health National Prescription Audit1 / SAMHSA National Survey on Drug Use and Health2 / CDC National Vital Statistics System3

The Opioid Crisis

Texas Drug Overdose Deaths 2015 9.4 deaths per 100K 2,588 deaths

DEA: 2016 National Drug Threat Assessment Controlled Prescription Drugs (CPDs) distributed nationwide Source: US Department of Justice, Drug Enforcement Administration National Drug Threat Assessment Summary, November 2016 11

DEA: 2016 National Drug Threat Assessment Methods and sources for users obtaining pain relievers Source: US Department of Justice, Drug Enforcement Administration National Drug Threat Assessment Summary, November 2016 12

Impact on Hospitals and Communities 1,000 people each day are treated in emergency departments for not using prescription opioids as directed. (CDC) The cost of an overnight opioid overdose hospital admission in Texas is $35,908. (AHRQ HCUP 2013) $1,964,000,000 Texas health care costs associated with opioid abuse, about $73 Per-Capita. (Matrix Global Advisors, April 2015) Neonatal Abstinence Syndrome (NAS) NAS babies in NICU - withdrawal inpatient costs hospitals an average of $66,000 for four months. Healthy babies costs hospitals around $4,000 during the first four months of life. (NPR 1/09/17) 27,315 babies were diagnosed with newborn drug withdrawal syndrome in 2013, a five-fold increase from a decade earlier. (Nationwide Hospital Reporting) Life expectancy in the US dropped for the second year in a row in 2016, nudged down again by a surge in fatal opioid overdoses. (NPR 12/21/17)

Opioid Overuse, Misuse and Addiction: A Public Health Crisis Overarching community and public health responses are focused reducing overdose incidence and overdose deaths, transmission of infectious diseases (HIV, Hep C) and related criminal behavior. Associated Prevention, Intervention and Treatment efforts are focused on interrupting the cycle that leads to these dangerous consequences and on restoring people s lives. Hospitals and physicians are engaged in changing treatment approaches and prescription practices to reduce the use of opioids.

Opioid Prescription Guidelines Texas has PMP (Prescription Monitoring Program)

Support Training & Purchase of Naloxone Naloxone (Narcan, Evzio) - A medication that blocks or counters the effects of opioids, especially in overdose to reverse respiratory depression. Often used in emergency situations by first responders, law enforcement, hospitals, treatment centers and families of opioid dependent individuals. States can use their Federal Substance Abuse Prevention and Treatment (SAPT) Block Grant to fund Naloxone education and purchase Naloxone for community distribution.

MAT Common medications used to treat opioid dependence MAT (Medication-Assisted Treatment) is a tool that works best in combination with counseling, therapy, intensive behavioral treatment and support programs. An antagonist is a drug that blocks opioids by attaching to the opioid receptors without activating them. Antagonists cause no opioid effect and block full agonist opioids. Examples are naltrexone and naloxone. Examples of full agonists are heroin, oxycodone, methadone, hydrocodone, morphine, opium and others. Buprenorphine is a partial agonist meaning, it activates the opioid receptors in the brain, but to a much lesser degree than a full agonist. Buprenorphine also acts as an antagonist, meaning it blocks other opioids, while allowing for some opioid effect of its own to suppress withdrawal symptoms and cravings.

Effective Treatment includes Prevention and Intervention Suggested practices in Hospital EDs & Urgent Care Centers Develop a substance use screening process (SBIRT) No replacement prescriptions for controlled substances that are lost, destroyed, or stolen Discourage administration of intravenous or intramuscular opioids No prescriptions for long-acting or controlled-release opioids When opioids are prescribed, provide patient counseling on proper usage, storage, and disposal of opioids Write prescriptions for the shortest duration possible (3 days) Refer patients with acute exacerbations of chronic pain to PCP and reduce prescriptions to no more than 3-5 days, if issued Require proper photo ID to issue prescriptions Consult the Prescription Monitoring Program (PMP) before writing opioid prescriptions for acutely painful conditions Develop way to track patients who may be seeking opioids from EDs

Effective Prevention, Intervention and Treatment Educate physicians, dentists, pharmacists, nurses Physicians educate consumers Consumer education and prevention advertising, news, internet Change prescriptive practices less opioids Reduce the number of doses per opioid prescription Promote non-medication alternatives to managing pain Involve addiction treatment professionals as needed Use SBIRT and other screening tools in all health care delivery settings Research non-narcotic alternatives to treat opioid addiction Create multiple pathways for people to access help Policymakers, govt. agencies, law enforcement and treatment providers collaborate, keep the attention and awareness focused

Contact Information Matt Feehery Senior Vice President & CEO Behavioral Health Services PaRC (Prevention & Recovery Center) 3033 Gessner Rd. Houston, Texas 77080 713-329-7272 matt.feehery@memorialhermann.org www.parc.memorialhermann.org