Página 1 de 6 NeuroGuide EEG and QEEG Analysis System NeuroGuide the most informative and comprehensive Conventional EEG and QEEG analysis system available. Modern and simple to use Windows Functions provide for Automatic Artifact Rejection, Dynamic FFTs with Comparisons to FFT Lifespan Eyes Open and Eyes Closed Norms covering the age from Birth to 82 years of age. NeuroGuide includes re-montaging to Average Reference or reference free Current Source Density (CSD) or Bipolar Montages, JTFA Instantaneous Power, Coherence, Phase Differences, Burst Metrics and Phase Reset and Bi- Spectral Analyses. NeuroGuide is also designed for use with the LORETA Key Institute Source Localization software for registration with the Talarich MRI Atlas from the Montreal Neurological Institute. NeuroGuide provides tab delimited output files of the edited EEG and the analyses that can be imported into any statistical package or database management system, NeuroGuide includes a TBI & LD discriminant functions, as well as an integrated statistical package as well as predictions of neuropsychological test scores using the Brain Performance Index. NeuroGuide Dynamic Editing Window. Split-Half Reliability and FFT Normative Comparisons of Selected Segments Reduces Artifact Easy KEY Inst. LORETA Integration of Selected EEG Segment or the Artifact Free Record Used for QEEG Report Writing UNIQUE FEATURES Lifespan Normative Comparisons (N = 625): Rel. Power, Abs. Power, Power Ratios, Coherence, Phase and Amp. Asymmetry. Automatic Artifact Rejection with Manual Editing Capability. Multiple EEG File Imports (Lexicor, NeuroScan, EDF, Cadwell, ASCII, Mindset, Mitsar, XLTEK, DeyMed, BrainMaster & others) Instantaneous Split-Half Reliability and test re-test reliability of Selected EEG Segments. Dynamic and Flexible FFT and Normative Comparisons in the Editing Mode. Eyes Open and Eyes Closed Lifespan Norms for Linked ears, average ref. and Current Source Density (CSD) and any bipolar combination of the 10/20 system Re-Montage to any Reference Arrangement, e.g., Average reference or Current Source Density (CSD) Export to the Key Institute LORETA equations and the Montreal Neurological MRI Database (standard in NeuroGuide). Time domain Output Files Formatted for Easy Import to LORETA Key Inst. NeuroGuide Color Bar Graphs of the Direction and Magnitude of EEG Change Required to Normalize the EEG using EEG Biofeedback EEG Coherence and EEG Phase Raw Values and Z Score Normative Comparisons Birth to 82 Years Tab Delimited Output Files for easy importing into statistical programs and database management systems. NeuroStat package for computing paired t-tests, ANOVA for pre vs. post treatment analysis as well as group comparisons (add on to the base price). NeuroBatch programs for automatic processing of large numbers of EEG files (add on to the base price). Raw or Edited EEG Printouts of Any Montage for Conventional EEG Analyses FFT using a 0.5 Hz resolution and 1 Hz Color Maps from 0 to 50 Hz Export edited EEG in Lexicor file format and ASCII FFT Normative Power Ratios, including Z scores for Theta/Hi-Beta, Alpha/Hi-Beta & lo-beta/hi-beta frequency bands Mild Head Injury Discriminant Function and TBI EEG Severity Index (add on to the base price) Learning Disability Discriminant Function (add on to the base price) LORETA normative databases of linked ears, average reference, eyes open and eyes closed - birth to 82 years of age (add on to the base price). LORETA source correlations to evaluate dynamic connectivity Brain Performance Index Prediction of Neuropsychological test scores with a 95% confidence band and including Full Scale IQ, Verbal I.Q. and Performance I.Q. (add on to the base price) JTFA for Instantaneous power, coherence, phase and amplitude asymmetry. JTFA feature detection to detect brain state changes such as drowsiness, sleep and spike & waves. A built in Help manual including tutorials. 24 channel Mindset EEG acquisition (add on to the base price). EEG Burst Metrics
Página 2 de 6 Cross-Spectra power, co-spectrum and quad-spectrum for in-phase and out-of-phase EEG analyses Complete 171 channel combination topographic maps Phase Reset and Phase and Frequency Locking measures Time Domain 3-Dimensional Source Localization for spike and wave and other conventional EEG analyses Bi-Spectral Analyses including Log-Log plots of the spectrum and 1/f distributions Up to 128 channel import capacity (128 channels are customized depending on labeling and channel order email us at qeeg@appliedneuroscience.com) Real-Time Feedback Between Reliable Artifact Free EEG and the QEEG Re-Montage NeuroGuide Window 85 channels is standard with custom 128 channel imports. You can Select or Create any Montage With Nearly Instant Screen Update Displays and Real-Time Comparisons to Norms Eyes Open & Eyes Closed LifeSpan Norms, Birth to 82 yrs. For Linked Ears, Ave. Reference and Current Source Density (CSD) Standard Features of NeuroGuide Deluxe (Basic) Including LifeSpan Norms EEG Coherence, Phase, Amp. Asym., Rel. Power, Power Ratios Eyes Closed LifeSpan Norms, Dynamic Split-Half Reliability, Dynamic FFT Editing, Automatic Artifact Rejection, Outputs to be used for LORETA 3D Localization, Launch the Key Institute LORETA Viewer, LORETA normative database (birth to 82 years), Tab Delimited Output, Conventional EEG Print Outs, Color Bar Graphs for Minimization of Z Scores, Eyes Open and Eyes Closed Linked Ears, Average Reference and Current Source Density Norms (i.e., Laplacian Norms), Lexicor Export, ASCII Export and multiple EEG file import, EEG burst metrics, time domain LORETA Z-Score tables and connection maps for Coherence, Phase, Asymmetry, Relative Power. Tab Delimited Raw-Score and Z-Scores Exportable to Excel, Systat, SPSS and all Database Management programs. Topographic maps for Raw-Score and Z-Score Relative Power in 4 frequency bands Topographic maps for Absolute and Relative Power Band Ratios, including Gamma frequencies (δ/θ, δ/α, δ/β; δ/γ, θ/α, θ/β, θ/γ, α/ β, α/γ, β/γ). FFT Absolute and Relative Power in Tab Delimited Format Split-Half Reliability Values for Each Channel and an Average Reliability Score all in Tab Delimited Format
Página 3 de 6 FFT Absolute and Relative Power in 0.5 Hz resolution from 0 to 50 Hz Color Bar Graphs of Raw Scores and Z scores Showing how much the EEG must change so that the Z Score = 0 1 Hz Topographic Color Maps, from Delta to the Gamma Frequency Band including and Absolute Power and Relative Power Z scores ASCII EEG Export and ASCII Digital EEG Printout as well as Export in Lexicor file format Multiple EEG file import capabilities, e.g., ASCII, Lexicor, NeuroData, NeuroScan, Mindset, NeuroGuide, Mitsar, EDF, BrainMaster, Capscan, Cadwell JTFA instantaneous power, coherence, phase and amplitude asymmetry Import up to 128 channels (128 channel import customized to the users labeling and channel order) JTFA feature detection to identify deviant EEG events and brain state changes such as drowsiness and sleep LORETA current source analyses using the Key Inst. LORETA program LORETA source correlation analyses to evaluate ROI coupling Flexible report generator with adjustable color schemes and Z score ranges First and second derivatives of the EEG time series Export of JTFA values and derivates Flexible export and print capabilities of the EEG traces EEG Burst Metrics Time Domain Source Localization for conventional EEG analysis Event markers with flexible sorting routines NeuroGuide Seamlessly Integrates to TBI and Learning Disability (LD) Discriminant Functions and Correlations with Neuropsychological Tests (purchased as an add on to the basic system) NeuroGuide s NeuroStat ($600 Add On) Seamlessly Integrates Dedicated Comparative Statistics EEG Pre vs. Post Treatment or Beginning Session vs. End of Session EEG and other comparisons
Página 4 de 6 Scientific Publications That NeuroGuide is Based On: EEG and Clinical Neurophysiol., 64: 123-143, 1986; Science, 236: 1110-1113, 1987; EEG and Clinical Neurophys., 73: 93-106, 1989; Journal of Neuroimaging, 5, 35-45, 1995; J. Neurotrauma, 14: 1-14, 1997; NeuroImage, 8(4), 307-326, 1998. NeuroImage, 7: 352-367, 1998; Brain Injury, 12: 13-21, 1999; J. Neuropsychiatry and Clin. Neuroscience 13(1): 77-87, 2001; Int. J. of Neuroscience, 107: 161-171, 2000; Clinical Neurophysiology, 112: 1729-1745, 2001; J. of Neurotherapy, 7(3/4): 87 121, 2003; Clinical Neurophysiology, 36(2): 116 122, 2005; Human Brain Mapping, 28(2): 118-133, 2007; Clinical EEG and Neuroscience, 38(1): 35-48, 2007; Human Brain Mapping, Jan. 24, 2008. Price and How To Order PACKAGE TYPE (INTRODUCTORY OFFER) PART NO. PRICE NEUROGUIDE DELUXE (BASIC) EEG REVIEW AND NG-1 LifeSpan Normative database Eyes Open & Included Closed FFT and Eyes Closed Birth to 82 years, Automatic artifact rejection, Launch LORETA Viewer in NeuroGuide Amplifier imports include: Lexicor NRS-24, (Basic) NeuroNavigator NeuroScan, Misar, NeuroData, Cadwell MindSet, BrainMaster & CapScan, XLTEK, NeuroPrax, etc. A single Mild Head Injury Discriminant Function and TBI-1 TBI Severity Index or LD Discriminant and Severity LD-1 Index =. Two Discrimiant Functions and severity indexes as a package =. Purchase one discriminant function for
Página 5 de 6 and then upgrade to a second for another LORETA Current Density Normative Database LOR-1 Birth to 82 years of Age LORETA 3D Source Correlation Normative Database Birth to 82 years of Age SC-1 * NeuroBatch Automatic Batch analysis software NB-1 NeuroStat An Integrated QEEG Statistics Package NS-1 Brain Performance Index Predict BPI-1 Connectivity Suite (contact dealer for pricing) CS-1 Dynamic Bi-Spectral Analyses (call) BS-1 NeuroGuide for BrainMaster (1 to 4 channels) = $1,200 NGBMr-1 (not an add on) 2 channel Z Score Biofeedback = call DLL-2 4 channel Z Score Biofeedback = call 19 Channel Z Score Biofeedback = call DLL-4 DLL-19 EEG Acquisition as an Add On Module inside of NeuroGuide (Neuropulse or Discovery or Deymed) 19 channel Surface EEG Biofeedback of Z scores. Includes power, coherence, phase, amplitude asymmetry, phase reset, Laplacian, Linked Ears & Ave. Reference. Also Includes a Symptom Check list + Surface EEG Z Scores to Inform Protocol Selections 19 channel Surface EEG Biofeedback of Z scores Includes all of NF1 + LORETA Z Scores to Inform Protocol Selections (must also purchase NF1 (NF1 + NF2) 3-Dimensional LORETA Z Score NeuroImaging Real- Time Brodmann Area Z scores, Functional Module Z Scores, Default Brain Z Scores. Includes a Symptom Check list + Surface EEG Z Scores + LORETA Z Scores to Inform Protocol Selections. Must also purchase NF1 & NF2 before purchase of NF3 (Total package of NF1 + Nf2 + NF3 = $5,000) Symptom Check List NF Protocol Generator add on (independent of NF1 NF3). Generates NF protocols based on qeeg analyses that can be exported. NP1, Disc1 & Dey1 NF1 NF2 NF3 SCL1 NeuroGuide EEG Viewer (Standalone EEG Import, Edit V1 Standalone EEG Acquisition (not an add on to A1 Neuroguide). Only provides for acquisition and saving of EEG data * Prices do not include costs for shipping and handling or sales tax, where applicable Ten month payment plan at 0% interest is Possible Call 727-244-0240 For further information: Call: (727) 244-0240; Fax: 727-392-1436 Write to: Applied Neuroscience, Inc. 228 176 th Terrace Drive Redington Shores, Fl 33708 Or E-Mail: qeeg@appliedneuroscience.com NeuroGuide s operates as a "Library function" for information retrieval and analysis and as an "Accounting and Communications" function by accessing a table of age matched means and standard deviations from an approximate Gaussian Distribution and computing age matched Z scores. There is no intended use for NeuroGuide to provide a medical diagnosis. A trained and qualified person is
Página 6 de 6 required to edit the NeuroGuide EEG samples and to interpret the numbers based on their competence and training. NeuroGuide should serve only as an adjunct or in combination to other information that the clinician may use to render a clinical judgment. FDA 510k indications for use are by qualified medical or clinical professionals for the statistical evaluation of the human electroencephalogram (EEG) and competent students and scientists for research purposes.