HVTN RAMP Mentors

Transcription

1 RAMP Scholars travel to an HVTN site and work closely with a mentor to conduct an HIV vaccine research project. We recommend that interested students Jenna Udren, RAMP Project Coordinator at HVTNawards@hvtn.org to be personally connected with an investigator whose field of interest and location match the student s. Below is a list of selected HVTN sites and the mentors available at each site. Some mentors have proposed a potential project that is available to RAMP scholars, but students are not limited to these projects or mentors. Some mentors do not list specific projects, and students are encouraged to contact them and find out what is available. All scholars are required to have a U.S. HVTN Investigator serve as a mentor. If the proposed project is at a site outside of the U.S., then a co-mentor from the international site is required. The on-site mentors should be HVTN investigators who have a track record of successful mentoring of medical or graduate students, or junior investigators, particularly from underrepresented groups. It is not required that the mentor be from the same institution or geographic region as the scholar. Mentor Name Address Site Name Site City Site Country Project/Topic Ideas HVTN Leadership and Operations Community education and social behavioral science for the AMP (Antibody-Mediated Prevention) Study; Social behavioral Andrasik, Michele mandrasik@fhcrc.org Core Seattle USA manuscript development and grant writing Archary, Derseree Baden, Lindsay Robert Bekker, Linda-Gail Desh.Archary@capris a.org CAPRISA ethekwini Clinical Research Site Durban South Africa Brigham and Women's LBADEN@BWH.HAR VARD.EDU Hospital Boston USA Lab projects Linda- Emavundleni Gail.Bekker@hivresearch.org.za Clinical Research Site Cape Town South Africa Mucosal antibodies (predominantly in the female genital tract), binding antibodies, looking at whether these antibodies have ADCC or ADCP activity DeRosa, Stephen and Frahm, Nicole sderosa@fredhutch.or g; nfrahm@fredhutch.or g HVTN Laboratory Seattle USA Identify immune measurements following vaccination that correlate with vaccine efficacy [9-12 months preferred]

2 Dietrich, Janan Perinatal Health Research Institute - Soweto Soweto- Johannesburg South Africa Relationship between BMI and motivation to participate in vaccine trials Willingness to participate in vaccine trials Mobile health and technologies Intersection between investigating biomedical, clinical and immunological risks for HIV BMI and relationship to HIV vaccine immune response (data analysis) Edupuganti, Sri sedupug@emory.edu The Hope Clinic Atlanta USA AMP Study-related topics Frank, Ian (general mentoring); Metzger, David (behavioral/recruit ment projects); Bar, Katherine (basic/lab science) franki@mail.med.upe nn.edu; dsm@mail.med.upen n.edu; bark@upenn.edu University of Pennsylvania Philadelphia USA Use of social media for recruitment and community education in HIV vaccine research Factors associated with retention in HVTN trials Mapping geographic distribution of HIV risk behavior in Philadelphia Evaluating HIV risk behaviors and attitudes towards risk behaviors among infected individuals Sexual risk behaviors and HIV awareness and attitudes among intravenous drug users Sequencing and phenotyping of founder viruses following HIV infection Goepfert, Paul paulg@uab.edu Alabama Vaccine Research Clinic Birmingham USA Lab projects related to T cells, HIV infection and vaccines

3 Lab projects: CyTOF for evaluation of vaccine induced T and B cell responses T cell receptor usage of HIV-specific T cells after natural infection or vaccination Kalams, Spyros Keefer, Mike Droplet digital PCR quantitation of virus s.kalams@vanderbilt. Edu Vanderbilt University Nashville USA specific T cells during natural infection or after vaccination Michael_Keefer@UR MC.Rochester.edu Victory Alliance Rochester, NY USA Clinical research Kobie, James Mayer, Kenneth James_Kobie@URM C.Rochester.edu University of Rochester Rochester, NY USA KMayer@fenwayhealt h.org Fenway Institute Boston USA Lab projects: Dynamics of the human memory B cell response to HIV vaccines Pre-clinical evaluation of B cell responses to novel adjuvants for HIV vaccines What is the scientific literacy of men who have sex with men in Boston about vaccines, pre-exposure prophylaxis, and microbicides? Enhancing engagement of minorities in HIV research (9-12 months) Assessing providers and at risk community members' readiness to participate in HIV prevention research trials

4 Mimiaga, Matthew vard.edu Fenway Institute Boston USA HIV prevention in the context of mental health conditions and substance abuse treatment and prevention. See this link for ideas. Mngadi, Kathy a.org CAPRISA ethekwini Clinical Research Site Durban South Africa MOTAR study ( mobile technology in the reporting of Reactogenicity- concept approved and proposal in draft) Writing a concept for Use of gene X-pert in diagnosis of VISP, compared to current HVTN algorithm Mulligan, Mark and Nagar, Shashi mark.mulligan@emor y.edu; shashi.nagar@emory. edu The Hope Clinic Atlanta USA social-behavioral and community research, e.g. Motivators and Barriers to Recruitment and Retention of African Americans in Atlantabased HIV Vaccine Trials

5 Nelson, LaRon ochester.edu University of Rochester Rochester, NY USA Examining factors that serve as barriers to accessing HIV prevention services for Black and Latino transgender men and women Investigating motivating factors for longitudinal participation in an HVTN trial among Black (Latino and non-latino) men who have sex with men How do religious beliefs influence participation and non-participation in HIV vaccine clinical trials for Black (Latino and non- Latino)? Does satisfaction with past healthcare experiences predict likelihood of participation in a HIV clinical trial? Does satisfaction with past healthcare experiences predict likelihood current engagement in health care? What effects do different types of stigma have on likelihood of clinical trial participation? Do some stigmas have stronger associations than others? Examine associations between selfdetermination theory constructs and HIV prevention behaviors of Black (Latino and non- Latino) MSM? Examine associations between selfdetermination theory constructs and healthcare-seeking behaviors of Black (Latino and non-latino) MSM? Scott, Hyman hyman.scott@sfdph.o rg Bridge HIV San Francisco USA Evaluate a community engagement strategy of storytelling through social media accounts using images.

6 Sobieszczyk, Magdalena (Magda) Stranix, Lynda Tieu, Hong Van and Koblin, Beryl Tomaras, Georgia and Seaton, Kelly Williams, Wilton and Haynes, Barton ia.edu er.org; nter.org e.edu; u edu; uke.edu HVTN RAMP Mentors Columbia University HIV Vaccine Unit New York USA UZ-UCSF Seke South Clinical Research Site Harare Zimbabwe Environmental exposures and HIV response New York Blood Center New York USA Duke Human Vaccine Institute Durham USA Duke Human Vaccine Institute Durham USA HIV and other infectious diseases epidemiology and biomedical prevention interventions Behavioral and social science factors associated with HIV vaccine trials, including recruitment, retention, risk assessment, and identifying populations at risk Research on disparities Lab projects - Antiviral T Cell Responses; Mucosal and Systemic Antibodies Molecular and biochemistry techniques used in the HIV-1 vaccine and immunology areas of focus (functional profile of the subdominant antibody response induced by the boost vaccine previously studied in the HVTN 505 efficacy trial)