Chin J Dis Control Prev 2018 Dec antiretroviral therapy ART. DOI /j. cnki. zhjbkz

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1 1238 Chin J Dis Control Prev 2018 Dec antiretroviral therapy ART % 14. 3% ART ART / / R R A DOI /j. cnki. zhjbkz Prevalence and factors influencing depression and anxiety among AIDS patients in Ili Prefecture CHEN Tao 1 WANG Wei 2 CHEN Zhi-Sheng 3 Deng Chao-ming 3 LIU Nai-peng 2 YE Shao-dong 4 WANG Xue-min 5 WANG Guizhen 6 LIU wei 1 ZHANG Hong-bo The Division of STD and AIDS Prevention and TreatmentIli Kazakh Autonomous Prefecture Center for Disease Control and Prevention Ili China2. Department of Epidemiology and Healthy StatisticsSchool of Public HealthAnhui Medical UniversityHefei China3. Ili Kazakh Autonomous Prefecture Center for Disease Control and Prevention Ili China4. The Division of HCV Prevention and TreatmentNational Center for AIDS /STD Control and PreventionChinese Center for Disease Control and PreventionBeijing China5. The Division of STD and AIDS Prevention and TreatmentYining Center for Disease Control and PreventionYining China6. The Division of STD and AIDS Prevention and Treatment DivisionYining County Center for Disease Control and PreventionYining County China Abstract Objective To investigate the prevalence of depression and anxiety symptoms and its influencing factors among AIDS who are receiving antiretroviral therapyartin Yili Kazakh Autonomous Prefecture of China. Methods The research was conducted in Yili Kazakh Autonomous Prefecture of China and data were collected from questionnaire and the system of AIDS follow-up management. Results Participants with symptoms of depression and anxiety accounted for 20. 6% and 14. 3% respectively in 412 participants. The results of Multivariate Logistic Regression analyses showed that participants with good knowledge of ART and better adherence to ART and taking part in Qiayi culture activity were less likely to have symptoms of depression. Divorceseparation or being widow were risk factors of depression. The results also presented that unemployed participants were more likely to have anxiety symptoms and anxiety symptoms were associated significantly with tobacco use. Conclusion Developing the strategy of mental health service and strengthening social and family support could improve mental health of people living with HIV. Key words HIV /AIDSAntiretroviral therapy /ARTDepressionAnxietyMental health Chin J Dis Control Prev WT zhanghongbo@ ahmu. edu. cn

2 acquired immunodeficiency syndrome AIDS human immunodeficiency virus HIV AIDS 66 self-rating anxious scale SAS self-rating depression scale SDS antiretroviral therapy ART HIV CD4 + T AIDS AIDS AIDS 1. 5 Epi Data HIV SPSS ART ART AIDS AIDS 2 Logistic ART AIDS α = ART HIV AIDS 100 AIDS ~ ± % 251 /412 AIDS 63. 8% 263 / % 332 / % 146 /412 HIV ART 2. 2 AIDS AIDS 20. 6% 85 / ART AIDS SDS 50 SAS AIDS AIDS ART HIV /AIDS ART HIV AIDS AIDS HIV % % 59 / % 19. 9% 14. 3% AIDS 32. 1% 16. 3% ART ART 2 = P = ART ART 35. 0% ART 24. 7% 2 = P 1 2 h ART = = P <

3 1240 Chin J Dis Control Prev 2018 Dec2212 Table 1 1 % Rate of depression and anxiety symptoms among different scio-demographic of participants % n% 2 P n% 2 P < ~ ~ ~ / / < OR = % CI0. 06 ~ % 22. 7% ART 2. 4 ~ ART 13. 3% % ART 27. 2% ART 30. 2% HIV 3 2 ~ % AIDS P < ART HIV AIDS 19. 9% 11. 4% 1 /5 1 /6 2 = P = = 1= HIV ART ART / / CD4 + T Logistic Forward α = / / OR = % CI ART ~ ART OR = % OR = % CI1. 01 ~ ART ART CI0. 24 ~ ART 1 /2OR = % ART CI0. 29 ~ AIDS ART

4 Table 2 2 The analysis results of the factors influencing depression and anxious symptoms n% 2 P n% 2 P < < ~ AIDS a Ⅰ Ⅱ Ⅲ Ⅳ CD4 + T < ~ ART ART a Fisher Logsitic 4 Logistic Table 3 The result of multiple logistic regression for factors associated with depression symptoms β s 珋 x P OR95% CI ~ ~ / / ART ~ ART ~ ~ Table 4 The result of multiple logistic regression for factors associated with anxious symptoms β s 珋 x P OR95% CI ~ ~ ~ ~ ART HIV /AIDS

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