Scientific Programme. Thursday 9 November Day 1. Venue: Century City Conference Centre. FIDSSA Official Opening Ceremony
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1 Thursday 9 November Day 1 Scientific Programme : Century City Conference Centre 15h00 19h00 Conference Registration FIDSSA Official Opening Ceremony Halls B & C 17h00 17h15 Welcome and Opening Marc Mendelson (FIDSSA President) PLENARY SESSION 1: Emerging and Re-Emerging Infectious Diseases (In partnership with ISID) Chair: Lucille Blumberg 17h15 17h45 17h45 18h15 18h15 18h45 African viruses flourishing in the diaspora Margheretta Isaacson Lecture Oyewale Tomori (Nigeria) Surveillance of emerging and re-emerging infectious diseases Larry Madoff (USA) The cost of delaying measles eradication David Durrheim (Australia) 18h45 21h00 Welcome Function & Trade Preview Exhibition Area
2 Scientific Programme Friday 10 November Day 2 Meet the IPC Nursing Expert Takeda Breakfast Symposium NICD Breakfast Symposium Meeting Room 11 Hall A Meeting Room 10 07h00 07h45 Quality of our drinking water, wider implications of water shortage in South Africa on the hospital environment Nonhlanhla Kalebaila Optimising treatment in the current crisis Stephan Harbarth (Switzerland) New improved strategies for reporting Notifiable Medical Conditions in South Africa: 2017 and beyond Portia Mutevedzi PLENARY SESSION 2: Drug-Resistant Infections (In partnership with ESCMID) Chair: Adrian Brink 16 08h00 08h30 Halls B & C Management of infections due to MDR gram-negatives: towards individualised therapy Jesus Rodriguez-Bãno (Spain) 08h30 09h00 Neonatal sepsis and drug-resistant infections Mike Sharland (UK) 09h00 09h30 One health approach to drug-resistant infections Sabiha Essack 09h30 10h00 Promoting patient participation in the strategy to combat Antibiotic Resistance Vanessa Carter 10h00 10h30 Refreshments & Poster Viewing Exhibition Area
3 Friday 10 November PARALLEL SESSION 1 Hall A Hall B Hall C Meeting Room 11 SASPID HIV & TB: Infants, Co-Infection, Treatment Failure SASCM New Directions in Clinical Microbiology STDSSA The Alarming Sti Epidemic In South Africa: Can We Improve Current Management Strategies? SASTM Shifting And Overstepping Boundaries Nicolette du Plessis Brian Eley Warren Lowman Chetna Govind Ranmini Kularatne Heather Jaspan Salim Parker Lee Baker 10h30 12h30 Management of TB in neonates and young infants (2) Adrie Bekker Treatment of HIV/TB co-infection in children (2) Helen McIlleron Third line ART in children: how are we doing? (2) James Nuttall Epidemiology of influenza- and respiratory syncytial virus (RSV)-associated hospitalisation in children aged <5 years in a setting with high HIV prevalence, South Africa, Meredith McMorrow Culture-confirmed tuberculosis in infants less than 3 months of age: A clinical description of 71 cases Lisa Frigati Treatment outcomes in perinatally-hivinfected children and adolescents after 10 years on antiretroviral therapy Kim Anderson Routine microbiome analysis in the clinical microbiology laboratory: now or never? (2) Mark Nicol Treatment of ESBL and carbapenemase producing Enterobacteriaceae: A casebased (2) Jesus Rodriguez-Bãno (Spain) Innovative Stewardship (2) Sabiha Essack Procalcitonin-guided antibiotic therapy for suspected and confirmed sepsis of patients in a surgical-trauma intensive care unit Rispah Chomba Can we trust the Xperts? An evaluation of the Xpert MRSA/SA BC system and assessment of potential clinical impact Kessendri Reddy Investigation of discrepancies between phenotypic and molecular methods for detection rifampicin susceptibilities from a tertiary diagnostic laboratory in Pretoria: towards consensus in rpob mutations Kudzai Nyazema 2016 STI prevalence in young men and women in KwaZulu Natal (1) Nuala McGrath STI and BV prevalence in young women in Cape Town and Soweto (10 mins) Shaun Barnabas New South Africa STI and BV management guidelines (1) Koleka Mlisana Rapid/point-of-care diagnostic for STIs: Needs, progress and challenges (1) Ranmini Kularatne GeneXpert for POC STI testing in South Africa (10 mins) Nigel Garrett Cytokine biomarkers triage test for STIs and BV (10 mins) Lindi Masson Behavioural modification to reduce STI incidence in adolescent women (10 mins) Linzi Rabinowitz PANEL DISCUSSION: The way forward (3) Q. Abdool Karim, N. McGarth, K. Mlisana, R. Kularatne, N. Garrett, JA. Passmore Yellow Fever (2) Oyewale Tomori (Nigeria) Zoonosis (2) Emily Mitchell Medical Tourism beyond nip and tuck (2) Adriano Dusé Bytes and bites from Barcelona (2) Salim Parker, Garth Brink, Lee Baker Implementation of a mobile application for Hand Hygiene monitoring: Smart, Simple and Interactive Angeliki Messina Odyssean malaria outbreak at a bush lodge in Madikwe Game Reserve, North West Province, October-November 2015 Genevie Ntshoe 12h30 13h30 Refreshments & Poster Viewing Exhibition Area
4 Friday 10 November PLENARY SESSION 3: Managing Infections in Adolescents and Pregnant Women Chair: Nelesh Govender 13h30 14h00 14h00 14h30 14h30 15h00 Halls B & C The intersection of HIV and NCD epidemics and clinical implications Mosepele Mosepele (Botswana) Adolescent vaccination strategies Greg Hussey Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa Quarrhaisha Abdool Karim 15h00 15h30 Refreshments & Poster Viewing Exhibition Area PARALLEL SESSION 2 Hall A Hall B Hall C Meeting Room 11 DR - TB - What s New? ICSSA Control of the Environment for IPC HIV Specific Challenges in HIV Management Management Systems in Rural Care Sean Wasserman Justyna Wojno Yolanda Walsh Lesley Devenish Yolanda van Zyl Halima Dawood Sipho Dlamini Tom Boyles Rosie Burton 18 15h30 17h30 The shorter regimen for MDR-TB: evidence and pitfalls (20 mins) Helen Cox Possibilities and challenges for a pan-tb regimen (20 mins) Robert Wallis Diagnostic discordance dilemma in TB Pitfalls and solutions (20 mins) Nazir Ismail The clinical pharmacology and drug interactions of Bedaquiline (20 mins) Helen McIlleron Introduction of drug resistant TB Reflex Testing in Kwa-Zulu Natal A descriptive analysis of MTBDRsl resistant isolates over a 9-month period Keeren Lutchminarain The incidence of discordant Rifampicin susceptibility results between genotypic and phenotypic methods in Mycobacterium tuberculosis complex isolates at Dr George Mukhari Hospital Tertiary Laboratory Caroline Maluleka Evaluation of methods for generation of in vitro mutants resistant to bedaquiline, clofazimine and linezolid from Mycobacterium tuberculosis reference strains Nabila Ismail Impact of effective treatment on TB transmission, lack of impact of XDR treatment on transmission, problem of reducing transmission in treatment failures (30 mins) Edward Nardell (USA) Limitations of natural ventilation and mechanical ventilation and room air cleaners in controlling airborne infection (30 mins) Tobias Van Reenen Environmental cleaning for persistent resistant organisms (20 mins) Marilyn Leadsom Importance of the environment; and newer technologies for environmental disinfection (20 mins) Adriano Dusé Risk assessment for the transmission of Infectious Diseases in the South African Police Services (SAPS) Lesley Devenish #CAUTI MUST FALL Shakiera Sallie Scaling up treatment for 7 million the innovations required (2) Ntombi Sigwebela Trailblazers: Lessons learned from the first ART programmes (2) Gary Maartens Cardiovascular disease in HIV (2) Loicea Achieng (Kenya) Current challenges of HIV research in children- where are the gaps while we wait for cure? (2) Helena Rabie The effects of the attributable fraction and the duration of symptoms on burden estimates of influenzaassociated respiratory illnesses in a high HIV-prevalence setting, South Africa, Stefano Tempia Strong association between higher risk sex and HIV prevalence at regional level: an ecological study of 27 sub-saharan African countries Chris Kenyon Austerity and healthcare delivery in rural areas: how do we set priorities? (2) Marije Versteeg-Mojanaga Challenges in caring for acutely ill AIDS patients in rural district hospitals (2) Hoffie Conradie Tackling the Hippo: Infectious diseases at household and community level in rural areas (2) Steve Reid Managing HIV resistance in a deeply rural setting. Can it be done? (2) Jenny Minnaar Prevalence and characterisation of food and waterborne bacterial pathogens in river water, meat from informal abattoirs, and stool from children with diarrhoea in Nyanga Township, Cape Town, South Africa John Bosco Kalule Outbreak preparedness and the NICD 24-hour hotline - a review of calls made to the hotline, August 2016-July 2017 Kerrigan McCarthy 17h30 18h30 ICSSA AGM IDSSA AGM STDSSA AGM SASPID AGM SASCM AGM SASTM AGM 18h30 19h15 FIDSSA AGM Hall B 19h30 Invited Faculty Dinner Delegates Evening At Leisure
5 Saturday 11 November Day 3 Trainee Session Beckman Coulter Breakfast Symposium Meeting Room 11 Hall A 07h00 07h45 Truth or Dare Meet the Expert Session for Trainees Panel Discussion Rob Davidson and Mosepele Mosepele Current Challenges and Emerging Resistance Detection in the Clinical Microbiology Laboratory Barbara Zimmer (USA) PLENARY SESSION 4 Spotlight on Infection Prevention Chair: Shaheen Mehtar 08h00 08h30 Hall B & C Prevention of hospital-acquired infections Stephan Harbarth (Switzerland) 08h30 09h00 Determining infectiousness in transmission for TB patients Edward Nardell (USA) 09h00 09h30 09h30 10h30 UVGI: New SA Guidelines Tobias van Reenen Poster Presentations Hall D Refreshments Exhibition Area
6 Saturday 11 November PARALLEL SESSION 3 Hall A Hall B Hall C Meeting Room 11 IDSSA New Insights into Viral Hepatitis Antimicrobial Research and Development (SAASP) Malaria / Tropical Vaccines John Black Wolfgang Preiser Marc Mendelson Adrian Brink John Frean Rob Davidson Gary Reubenson Sipho Dlamini 20 10h30 12h30 Why is the elimination of viral hepatitis possible? (25 min) Wendy Spearman PMTCT for hepatitis B more than just the pregnancy (20 min) Neliswa Gogela Hepatitis E in South Africa (15 min) Tongai Maponga The hidden co-factor with hepatitis B (15 min) Stephen Korsman Unravelling Hepatitis C (20 min) Mark Sonderup Hepatitis A seroprevalence in South Africa. Are we in epidemiological transition? Annabel Enoch Preliminary evaluation of dried blood spots to test for Hepatitis C virus (HCV) antibodies among people who inject drugs, sex workers and men who have sex with men Lucinda Gaelejwe H3D What s new in the antimicrobial R&D pipeline (30 min) Greg Basarab Harnessing developing technology to combat drug resistance (30 min) Richard Gordon New economic models for Research & Development: Lessons from DRIVE-AB (30 min) Stephan Harbath (Switzerland) Re-vitalising the pipeline through the Global Antibiotic Research & Development Partnership (GARDP) (30 min) Manica Balasegaram (Switzerland) Malaria (25 min) Lucille Blumberg Wormy tails (25 min) John Frean PUO in the Tropics (25 min) Helen van der Plas Neglected Tropical Diseases? Cases from the Field (25 min) Rob Davidson (UK) Rabies Virus down-regulates the expression of Actin and Microtubule associated proteins in neurons Waqas Ahmad Coronavirus diversity in South African bats A risk for human health? Wolfgang Preiser Pertussis in South Africa: The modern epidemiology of an old disease (25 min) Ute Hallbauer Role of evidence-based vaccinology in strengthening immunisation programmes (25 min) Benjamin Kagina TB Vaccine (25 min) Willem Hanekom (USA) Vaccines for Rheumatic Fever: The African connection (25 min) Babu Muhamed Meningococcal carriage amongst first-year students on entering University: Is there a need in South Africa for meningococcal prevention strategies? Susan Meiring 12h30 13h30 Lunch Exhibition Areas PLENARY SESSION 5 A Plenary Pot Pourri Chair: Gary Maartens 13h30 14h00 14h00 14h30 14h30 15h00 15h00 15h30 The Genital Microbiome Jacques Ravel (USA) Stowaways: A One Health Perspective Emily Mitchell Advanced HIV and the seriously ill: challenges in low-resource settings Rosie Burton Refreshments Exhibition Areas
7 Saturday 11 November PARALLEL SESSION 4 Hall A Hall B Hall C Meeting Room 11 15h30 17h30 SA 17h30 18h00 Maternal Infections Lindi Masson Ranmini Kularatne The vaginal microbiome during pregnancy and preterm delivery (20 mins) Jacques Ravel (USA) GBS during pregnancy (20 mins) Charlene Africa The timing of antiretroviral therapy (ART) to HIV infected mothers before or during pregnancy has no association with placental inflammation and pathology (20 mins) Clive Gray Maternal infections influence infant gut microbiota and immunity (20 mins) Heather Jaspan Influence of HIV infection on breast Milk microbiome and metabolome (20 mins) Elloise du Toit Prevalence and molecular analysis of Mycoplasma Genitalium strains isolated from pregnant women at an Academic Hospital in Pretoria, South Africa Marcelle le Roux Evaluation of two commercial NAATs for detection of C. trachomatis, N. gonorrhoeae and T. vaginalis in endocervical swabs collected from pregnant women attending the DGMAH Innocent Ngwenya Refreshments Exhibition Areas Fungal Infections Nelesh Govender Graeme Meintjes Global emergence of Candida auris (2) Nelesh Govender Prevention and management of antifungal-resistant infection in the ICU (2) Adrian Brink New antifungal treatment strategies for Cryptococcosis Update from recent clinical trials (2) Graeme Meintjes What s in the diagnostic pipeline for invasive mycoses? (2) Charlotte Sriruttan Independent risk factors associated with Candida auris candidaemia in South Africa An analysis of national surveillance data, Erika van Schalkwyk Diagnostics and New Technologies for Infections Tom Boyles Colleen Bamford Urinary LAM (20 mins) Keertan Dheda Recent advances in diagnostics for active TB (2) Mark Nicol Current and emerging legionella diagnostics (2) Nicole Wolter The performance of Cepheid Xpert HPV (20 mins) Zizipho Mbulawa Molecular characterisation of Salmonella Typhi isolates from South Africa, Nomsa Tau Comparing commercial probiotic and vaginal Lactobacillus strains to evaluate whether probiotics marketed for vaginal health in South Africa are suitable for bacterial vaginosis treatment Anna-Ursula Happel Comparison of nucleic acid amplification tests to detect sexually transmitted infections from virginal specimens Nireshni Mitchev Antibiotic Stewardship - Open papers (SAASP) Dena van den Bergh Andrew Whitelaw Evaluation of colistin utilisation across multiple South African Private Hospitals: Indeed it's time for Colistin Stewardship Angeliki Messina Assessing the impact of Antimicrobial Stewardship ward rounds using an app-based data collection tool in two Public Hospitals in the Eastern Cape, South Africa David Stead Characterising antibiotic-resistant pneumococci in the nasopharynx of healthy South African infants using shotgun sequencing and conventional typing Rendani Manenzhe Knowledge, attitudes and perceptions of Antimicrobial Resistance amongst private practice patients' and prescribers' in South Africa Dena van den Bergh Klebsiella pneumoniae ST307: A silent pathogen on the rise in South Africa Michelle Lowings Navigating the promise of technology in Antibiotic Stewardship Angeliki Messina Antibiotic consumption after two years of Antimicrobial Stewardship ward rounds in the Medicine Department at a Tertiary Hospital in the Eastern Cape Ya-Ying Wang Investigating Antimicrobial Resistance in enteric bacteria within a community setting using a one-health approach Chinyere Okoro ETHICS SESSION Chair: Sipho Dlamini Halls B&C 18h00 18h30 18h30 19h00 19h00 19h00/19h30 The ethics of Antimicrobial use, Antimicrobial Stewardship, and Antibiotic Resistance Charles Feldman The ethics of communication between the Doctor and Patient: The role of social media in facilitating best patient outcomes Gundo Nevhutanda Close of Conference Cape Malay Evening and SA Wine Tasting Century City Hotel, Square Café
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