Anti-tuberculosis drug resistance in the world and rapid diagnosis of tuberculosis
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1 Anti-tuberculosis drug resistance in the world and rapid diagnosis of tuberculosis Chiyoji ABE acquired drug resistance primary drug resistance HIV 1 3 INHRFP MDR-TB DOTSDirectly Observed Treatment, short course, 4 14 World Health Organization, WHO International Union Against Tuberculosis and Lung Disease, IUATLD WHOIUATLD 5 8 9, WHOIUATLD 2drug resistance among new casesdrug resistance among previously treated cases Nippon Becton Dickinson Diagnostic Systems (1 Gotanda, Tsuchifune, Fukushima-shi)
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4 MDR DOTS MDR MDR MDR MDR Tashkent Baku Donetsk MDR MDR MDR Orel Tomsk MDR Orel 3Tomsk 1.3 MDR HIV settings HIV HIV HIV 2 Donetsk HIV MDR 14.8HIV MDR.4P HIV P XDR-TBExtensively drug resistant TB INH RFP fluoroquinolone KMAMKCPM 1 XDR-TB XDR-TB 35 XDR-TB MDR-TB MDR-TB XDR-TB MDR-TB
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7 587 n MB-Redox MGIT 2 MB-Redox MGIT + MB-Redox +MGIT 133 MOTT MOTT CDC 21 MGIT MB- Redox MPB64 TB 16, 17 15, n 80 MOTT42 MB Redox MGIT MOTT n 50 MOTT TB TB MB RedoxMGIT0.1ml TB M. kansasii TB
8 Abe13 14 Carpentier15 Ichiyama16 Wang19 Catanzaro00 Scarparo00 Bergman00 Pierslmoni(02 Iinuma03 03 Takakura05 Boehme07 Pandey08 MTD Amplicor BD Probe ICAN TRC LAMP MTD : Transcription-mediated amplification Amplicor : Polymerase chain amplification BD Probe : Strand displacement amplification ICAN : Isothermal and chimeric primer-initiated amplification of nucleic acids TRC : Transcription reverse-transcription concerted reaction LAMP : Loop-mediated isothermal amplification M. avium M. intracellulare M. avium M. intracellulare NCCLSNational Committee for Clinical Laboratory Standards, Clinical and Laboratory Standards Institute, CLSI Middlebrook 07 BACTEC MGIT 0 AST MIC MTB-1 MGIT 0 AST , 22 INH MGIT 0 AST 1,112 MGIT 0 AST INH- INH- RFP SM EB BACTEC TM MGIT 0 AST MGIT
9 ATS CLSI M. avium complex M. kansasii M. marinum CAM CAM RFPRFPRBT, EB, INH, CAM,FQ, AMK, SA AMK, CFX, CAM, DOXY, FQ, IPM, Linezolid, SA, TOB 66 INH 30 CLSI Middlebrook 7H katG inha MGIT 0 AST 24 INH 2.9 INH INH MGIT 0 AST Mycobacterium kansasii Mycobacterium avium complex American Thoracic Society, ATS CLSI, M. avium complex CAMM. kansasii RFP RFP HIV Centers for Disease Control and Prevention, CDC, Centers for Disease ControlCDC: Nosocomial transmission of multidrug-resistant tuberculosis among HIV-infected persons Florida and New York, Morbid Mortal Weekly Rep. : 585-5, Dooley S, Jarvis WR, Martone WJ, Snider DE Jr : Mul-
10 tidrug-resistant Mycobacterium tuberculosis. Ann Intern Med. : 7-9, Snider DE Jr, Roper WL : The new tuberculosis. N Engl J Med. : , World Health Organization : Treatment of tuberculosis : guidelines for national programmes. 3 rd ed. WHO, Geneva, Switzerland, WHOIUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance : Anti-tuberculosis drug resistance in the world. WHOTB.229. WHO, Geneva, Switzerland, WHOIUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance : Anti-tuberculosis drug resistance in the world. Report No.2. Prevalence and trend. WHOCDSTB WHO, Geneva, Switzerland, WHOIUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance : Anti-tuberculosis drug resistance in the world. Report No. 3. WHOHTMTB WHO, Geneva, Switzerland, WHOIUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance : Anti-tuberculosis drug resistance in the world. Report No. 4. WHOHTMTB WHO, Geneva, Switzerland, Abe C, Hirano K, Wada M, Aoyagi T : Resistance of Mycobacterium tuberculosis to four first-line anti-tuberculosis drugs in Japan, 17. Int J Tuberc Lung Dis. : 46-52, Tuberculosis Research CommitteeRyoken: Drug-resistant Mycobacterium tuberculosis in Japan : a nationwide survey, 02. Int J Tuberc Lung Dis. : , Hirano K, Kazumi Y, Abe C, Mori T, Aoki M, Aoyagi T : Resistance to anti-tuberculosis drugs in Japan. Tuberc Lung Dis. : , : 00.,, : 07.,, ,,, :,.. : , ,,,,,,,,,, : MB Redox.. : , Abe C, Hirano K, Tomiyama T : Simple and rapid identification of the Mycobacterium tuberculosis complex by immunochromatographic assay using anti-mpb64 monoclonal antibodies. J Clin Microbiol. : 36-36, Hirano K, Aono A, Takahashi M, Abe C : Mutations including IS6110 insertion in the gene encoding the MPB64 protein of Capilia TB-negative Mycobacterium tuberculosis isolates. J Clin Microbiol. : 390-3, :.. : , :... : 5-5, 17. Clinical and Laboratory Standards Institute : Susceptibility testing of Mycobacteria, Nocardiae, and other aerobic Actinomycetes ; approved standard. NCCLS document M- 24A, Clinical and Laboratory Standards Institute, Wayne, PA, ,, : BACTEC MGIT 0 :.. : , Aono A, Hirano K, Hamasaki S, Abe C : Evaluation of BACTEC MGIT 0 PZA medium for susceptibility testing of Mycobacterium tuberculosis to pyrazinamidepza: compared with the results of pyrazinamidase assay and Kyokuto PZA test. Diagn Microbiol Infect Dis. : , 02.,,,,,,,,,,,,,,,,, : MGIT 0 MGIT AST.. : , Abe C, Kobayashi I, Mitarai S, Wada M, Kawabe Y, Takashima T, Suzuki K, Sng L-H, Wang S, Htay HH, Ogata H : Biological and molecular characteristics of Mycobacterium tuberculosis clinical isolates with low-level resistance to isoniazid in Japan. J Clin Microbiol. : 23-28, 08. American Thoracic Society Documents : An Official ATSIDSA Statement : Diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. : , 07. Tenover FC, Crawford JT, Huebner RE, Geiter IJ, Horsburg CR Jr, Good RC : The resurgence of tuberculosis : is your laboratory ready? J Clin Microbiol. : ,13. 27Centers for Disease Control and Prevention : National plan for reliable tuberculosis laboratory services using a systems approach : Recommendations from CDC and the Association of Public Health Laboratories Task Force on Tuberculosis Laboratory Services. Morbid Mortal Wkly Rep. : 1-12, 05.
Kekkaku Vol. 79, No. 11: ,
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