SCIENTIST E. DEGREE (if applicable)

Transcription

1 BIOGRAPHICAL SKETCH Provide the following information for the key personnel in the order listed for Form Page 2. Follow the sample format for each person. DO NOT EXCEED FOUR PAGES. NAME PRADEEP ARAVINDAN MENON POSITION TITLE SCIENTIST E EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) INSTITUTION AND LOCATION DEGREE (if applicable) YEAR(s) FIELD OF STUDY Maulana Azad Medical College, New Delhi M.B.B.S 1984 Medicine Madras Medical College D.P.M 2004 Psychiatry Association of Clinical Research Professionals, Alexandria, VA - ICH CRC Examination in September 2006, NIE, ICMR, Chennai MPH July Epidemiology/ Public June 2015 Health A. Research and/or Professional Experience Jan Dec 1986 Junior Resident in Medicine (6 months) and Surgery (6 months), In Maulana Azad Medical College New Delhi Jan 1987 Dec 1987 Junior Resident in Pediatrics, Lisie Hospital, Cochin Jan 1988 May 1994 Causality / Resident Medical Officer, Lisie Hospital, Cochin June 1994 Oct 1999 Research Officer, National AIDS Research Institute, ICMR, Pune Nov 1999 May 2007 Senior Research Officer, National Institute for Research in Tuberculosis (formerly Tuberculosis Research Centre) Chennai June 2007 Aug 2012 Scientist D, National Institute for Research in Tuberculosis Sept., to date Scientist E at NIRT, ICMR, Chennai Membership Life member of Indian Psychiatric Society Life Member of Indian Medical Association B. Selected Publications 1. Evidence for high prevalence and rapid transmission of HIV among individuals attending STD clinics in Pune, India. Mehendale S, Shepherd M, Divekar A, Gangakhedkar R, Kamble S, Menon PA, Yadve R, Risbud A, Paranjape R, Gadkari D, Quinn T, Bollinger R & Rodrigues J. (Indian J Med Res 104 December 1996, pp ). 1

2 2. Increasing trend of HIV seroprevalence among pulmonary tuberculosis patients in Pune, India. Paranjape RS, Tripathy SP, Menon PA, Mehendale SM, Khatavkar P, Joshi PD, Patil U, Gadkari DA & Rodrigues JJ. (Indian J Med Res 106, September 1997, pp ). 3. Clinical and Radiological presentation of Tuberculosis in HIV seropositive and HIV seronegative patients in Pune. Joshi DR, Toshniwal R, Tripathy SP, Menon PA, Khatavkar P, Paranjape RS, Mehendale SM & Gadkari DA. (Procedings of first National Conference on HIV/AIDS Medicine Pune th November 1996, pp 35-39). 4. Lymphocyte subpopulations in HIV seropositive and HIV seronegative Tuberculosis patients in Pune, India. Tripathy S, Menon PA, Joshi DR, Patil U, Gadkari DA & Paranjape RS. (Indian Journal of Medical Research June 2000). 5. Sentinel Surveillance for HIV infection in tuberculosis patients in india. S. Tripathy, D.R. Joshi, S.M. Mehendale, P. Menon, A.N. Joshi, S.V. Ghorpade, M.J. Patil and R.S. Paranjape. Indian J Tub 2002; 49: Pulmonary tuberculosis in HIV positive individuals preliminary report on clinical features and response to treatment. Swaminathan Soumya, Sangeetha A, Arun Kumar, Menon PA, Thomas B, Shibi K, Ponnuraja, Rajshekhar S. Indian Journal Of Tuberculosis 2002: 49; The sounds of the waves are frightening. Experiences of school children post Tsunami A report from India. Beena E Thomas, Pradeep A Menon, Indian Council of Medical Research Annual report The sounds of the waves are frightening. Experiences of school children post Tsunami A report from India. Beena E Thomas, Pradeep A Menon, web page in The Lancet., March 18, Impact of HIV infection on radiographic features in patients with pulmonary tuberculosis. Soumya Swaminathan, G. Narendran, Pradeep A. Menon, C. Padmapriyadarsini, N.Arunkumar, N.M. Sudharshanam, S. Ramesh Kumar and S. Chandrasekhar. Indian J Chest Dis Allied Sci 2007; 49: Localized Pulmonary Mycobacterium avium Disease in Acquired Immunodeficiency Syndrome. Soumya Swaminathan, Padmapriyadarsini.C, Ranjani Ramachandran, Pradeep A Menon, Nalini S Mohan, Kubendiran G, Paramasivan C.N. J Int Assoc Physicians AIDS Care (Chic Ill). 2007; 6(4): Study of ABCB1 polymorphism (C3435T) in HIV-1-infected individuals from south India. Siddharth Bakshi, Geetha Ramachandran, Karunaianandham Ramesh, Agibothu K. Hemanthkumar, Suresh Anitha, Chandrasekaran Padmapriyadarsini, Gopalan Narendran, Pradeep A. Menon, Sikhamani Rajasekaran, Soumya Swaminathan. Br J Clin Pharmacol. 2008; 65(5): Soumya Swaminathan, C.N.Deivanayagam, P. Venkatesan, S.Rajasekaran, C. Padmapriyadarsini, Pradeep. A. Menon, 2

3 C.Ponnuraja, Meenalochani Dilip, P.R.Narayanan. Long term follow up of HIV TB patients treated with 6 months intermittent short course chemotherapy (CAT I regimen). The National Medical Journal of India 2008; 21: Ramachandran G, Hemanth Kumar AK, Rajasekaran S, Kumar P, Ramesh K, Anitha S, Narendran G, Menon P, Gomathi C, Swaminathan S. CYP2B6 G516T polymorphism but not rifampin coadministration influences steady-state pharmacokinetics of efavirenz in human immunodeficiency virus-infected patients in South India. Antimicrob Agents Chemother 2009; 53(3): Swaminathan S, Narendran G, Venkatesan P, Iliayas S, Santhanakrishnan R, Menon PA, Padmapriyadarsini C, Ramachandran R, Chinnaiyan P, Suhadev M, Sakthivel R, Narayanan P. Efficacy of a 6 vs. a 9-month Intermittent Treatment Regimen in HIV-infected TB Patients: A Randomized Clinical Trial. Am J Respir Crit Care Med 2010; 181(7): C. Padmapriyadarsini, S. Swaminathan, M. J. Karthipriya, G. Narendran, Pradeep Aravindan Menon. Morphologic and Body Composition Changes are different in Men and Women on Generic Combination Antiretroviral Therapy Observational Study. JAPI 2010; 58: Padmapriyadarsini C, Ramesh Kumar S, Norma Terrin, Narendran G, Pradeep A Menon, Geetha Ramachandran, Sudha Subramanyan, Perumal Venkatesan, Christine Wanke, Soumya Swaminathan. Dyslipidemia among HIV-infected tuberculosis patients taking Once-daily Non-Nucleoside Reverse Transcriptase inhibitor based Antiretroviral Therapy in India. Clin Infect Dis 2011; 52(4): Soumya Swaminathan, Padmapriyadarsini C, Venkatesan P, Narendran G, Ramesh Kumar S, Sheik Iliayas, Pradeep A Menon, Sriram Selvaraju, Pooranagangadevi N, Bhavani PK, Ponnuraja C, Meenalochani Dilip, Ranjani Ramachandran. Efficacy and Safety of once-daily nevirapine or efavirenz based antiretroviral therapy in HIV-associated Tuberculosis: A Randomized Clinical Trial. Clinical Infectious Diseases 2011; 53(7): Hemanth Kumar, A.K., Ramachandran, G., Rajasekaran, S., Padmapriyadarsini, C., Narendran, G., Menon, P., Narayanan, P.R. and Swaminathan, S. Pharmacokinetics of rifampicin during antiretroviral treatment with non-nucleoside reverse transcriptase inhibitors. SAARC J Tuberc Lung Dis HIV/AIDS 5 (2008) Narendran G, Andrade BB, Porter BO, Chandrasekhar C, Venkatesan P,Menon PA,Subramanian S, Padma Priyadarsini C,Kumar S,Ravichandran N,Raja K,BhanuK,Mahilmaran A,sekar L,Sher A,sereti I,Swaminathan Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) in HIV Patients with Culture Confirmed Pulmonary Tuberculosis in India and the Potential Role of IL-6 in Prediction. PLOS ONE 2013; 8(5): e63541.doi: /journal.pone ( Impact factor ) 20. Ramesh Kumar S, Narendran Gopalan, Paru Patrawalla, Pradeep 3

4 Menon, Kenneth Mayer, Soumya Swaminathan. Immune Reconstitution Inflammatory syndrome in HIV-infected patients with and without prior tuberculosis. Int J STD AIDS. 2012; 23(6): ( IF-1.086) 21. Soumya Swaminathan, Pradeep A Menon, Narendran G, Venkatesan P, Ramesh Kumar S, Ranjani Ramachandran, Ponnuraja C, Sheik Iliayas, Padmapriyadarsini C, Pooranaganga Devi N, Thiruvalluvan E, Pho M, Wares F, Narayanan PR. Efficacy of a six-month versus a 36-month regimen for prevention of tuberculosis in HIV-infected persons in India: A Randomized Clinical Trial. Plos One. 2012; 7(12):e (IF-4.092) 22. Kolappan Chockalingam, Chandrasekaran, Vedachalam, Subramani Rangasamy, Gomathi Sekar, Srividya Adinarayanan, Soumya Swaminathan, Pradeep Aravindan Menon. Prevalence of Tobacco Use in Urban, Semi Urban and Rural Areas in and around Chennai City, India. Plos One. 2013;8(10):e76005.( IF ) ( Corresponding Author ) 23. R Kumar, PA Menon, C Ponnuraja, C Padmapriyadarsini, G Narendran, S lliayas, S Subramanyam, V Kumar, S Swaminathan. HIV-infected patients retreated for tuberculosis with intermittent Category II regimen-treatment outcome at 24-month follow-up. The Indian Journal of Tuberculosis.2014 Jan;61(1): R Kumar, PA Menon, C Ponnuraja, C Padmapriyadarsini, G Narendran, S lliayas, S Subramanyam, V Kumar, S Swaminathan. HIV-infected patients retreated for tuberculosis with intermittent Category II regimen-treatment outcome at 24-month follow-up. The Indian Journal of Tuberculosis 2014;61(1): Gopalan Narendran, Pradeep Aravindan Menon, Perumal Venkatesan, Krishnamoorthy Vijay, Chandrasekaran Padmapriyadarsini, Santhanakrishnan RameshKumar, Kannabiran Perumal Bhavani, Lakshmanan Sekar, Sivaramakrishnan Narayan Gomathi, Chockalingam Chandrasekhar, Satagopan Kumar, Rathinam Sridhar, Soumya Swaminathan. Acquired Rifampicin Resistance in Thrice-Weekly TB Therapy: Impact of HIV and Antiretroviral Therapy. Clinical Infectious Diseases 2014, ciu674. IF Kawsar R. Talaat, Subash Babu, Pradeep Menon, N. Kumarasamy, Jabin Sharma, Jeeva Arumugam, Kalaivani Dhakshinamurthy, Ramalingam Srinivasan, S. Poongulali, Wenjuan Gu, Michael P. Fay, Soumya Swaminathan, Thomas B. NutmanTreatment of W. bancrofti (Wb) in HIV/Wb Coinfections in South India. Research Article published 20 Mar 2015 PLOS Neglected Tropical Diseases /journal.pntd Soumya Swaminathan, Padmapriyadarsini C, Ponnuraja C, Ranjani Ramachandran, Sriram Selvaraju, Ramesh Kumar S, Pradeep A Menon, Narendran G, Sheik Iliayas, Pooranagangadevi N, Bhavani PK, Thiruvalluvan E, Venkatesan P. Treatment outcomes 4

5 among HIV co-infected tuberculosis patients treated with oncedaily antiretroviral therapy. Accepted for publication in the International Journal of Tuberculosis and Lung Diseases. C. Book Chapter: 1. PA Menon, Soumya Swaminathan, JR Sankaran. Multidrug-resistant tuberculosis (MDR-TB). Clinical Medicine Update Indian Association of Clinical Medicine. Pg D. Training and Workshop / Conferences attended 1. ICMR Training programme in Uganda (Makerere University) from 16 th October to 23 rd October Indo French Meeting on Traditional Remedies in HIV/AIDS on November NIE, Chennai National conference of Indian Psychiatry Society at Chandigarh, 28 th January 1 st February South Zone Conference of Indian Psychiatric Society at Calicut from 14 th October to 16 th October National Conference of Indian Psychiatric Society at Mumbai from January 5 th to January 8 th South Zone Conference of Indian Psychiatric Society at Mangalore from October, National Conference of Indian Psychiatric Society at Chennai from 4 th to 7 th January International Symposium on Obsessive-Compulsive Disorder (OCD) at Bangalore from 10 th to 11 th November th Annual National Conference of Indian Psychiatric Society at Kolkata from 3 rd to 6 th January st Annual National Conference of Indian Psychiatric Society at Agra from 8 th to 11 th January nd Annual National Conference of Indian Psychiatric Society held at Jaipur from January 17 to 20, th Conference on Retroviruses and Opportunistic Infections (CROI 2010) in San Francisco, California from February 16 to 19, Delivered a talk on INH prophylaxis in HIV positive patients in the Workshop for rolling out Operational Research on INH prophylaxis in HIV positive patients in India held at NACO, New Delhi from April 26 to 27, rd Annual National Conference of Indian Psychiatric Society held at New Delhi from January 16 to 19, th Annual National Conference of Indian Psychiatric Society held at Kochi from January 19 to 22, RED CAP Data Management Trainning at National Institute Of Epidemiology, ICMR Chennai- ( ICMR-Wanderderg University Joint Programme) TH Annual National Psychiatry Conference at Bangalore 17 th to 29 th Jan., Annual Workshop of RNYCP at Jaipur- 31 st Jan to 1 st Feb.,

6 19. Presently pursuing Masters In Public Health ( MPH) at NIE, ICMR, Chennai ( July June 2015) D. Projects undertaken: 1. A Randomized Controlled Clinical Trial of Tuberculosis Preventive therapy in HIV-infected individuals starting on Antiretroviral Therapy 2. A Randomized Controlled Clinical Trial Comparing Daily Vs. Intermittent 6 Months Short Course Chemotherapy in reducing Failures & Emergence of Acquired Rifampicin Resistance (ARR) in patients with HIV and Pulmonary TB 3. Changes in HIV viral load in patients undergoing treatment for filarial infection 4. Evaluation of safety and efficacy of two different once daily anti-retroviral treatment regimens along with anti-tuberculosis treatment in patients with HIV-1 and tuberculosis 5. To study the efficacy of two prophylaxis regimens for TB in HIV positive persons. 6. Randomized clinical trial to assess the efficacy of short course regimens for the treatment of HIV associated tuberculosis. 7. Prevalence of Tuberculosis in Chennai City Epidemiological Study. 8. Influence of Tobacco Smoking in Pulmonary Tuberculosis Patients Epidemiological Study. 9. Community workers Solidarity in Case management of Tuberculosis- operational study. 10. Effect of diabetes on tuberculosis severity.( EDOTS) 6