: Dr. R.S. Paranjape Designation : Director and Scientist G Date of Birth : 20/10/1952 Department : Immunology. Degree Year Institute / University

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1 Name : Dr. R.S. Paranjape Designation : Director and Scientist G Date of Birth : 20/10/1952 Department : Immunology Address : rparanjape@nariindia.org, director@nariindia.org Educational Qualification : Degree Year Institute / University Ph.D University of Madras M.Sc. (Medical Microbiology) 1975 All India Institute of Medical Sciences B.Sc. (Zoology) 1972 Pune University Areas of Interest: After post graduation from All India Institute of Medical Sciences, research career began at the Tuberculosis Research Center. Primary area of research was in the Immunology of Filariasis. Notable work in the area includes identification and characterization of circulating filarial antigen, development of monoclonal antibodies against the antigen and establishment of the diagnostic test for detection of circulating antigen. Immunology of Tuberculosis was the other area of research. The work included the study of cell-mediated immune response in pulmonary tuberculosis patients and tuberculous meningitis. Joined the National AIDS Research Institute in 1993 and had a major role in establishing the laboratories at the Institute. Immunology of HIV infection is the main area of interest. The initial work established the presence of strong, poly-clonal cross-clade cytotoxic T lymphocyte response in the early seroconverters. Subsequent work has shown that patients infected with HIV-1C show cross-clade as well as cladespecific response. A prospective study on recent seroconverters have shown that there is weak association of clade-specific consistent response with lower plasma virus load. The repertoire of CTL epitopes recognized by HIV infected patients is being delineated. The other studies include the study of neutralizing antibodies in HIV infection, nef gene diversity, screening of herbal and other preparations for anti-hiv activity in vitro. As the Officer-in-Charge, have had greater role of coordinating and directing the research activities of the Institute. The role also involves generation of funds through intra- and extra-mural projects, capacity building through infra-structure development and training and overall leadership for the research.

2 Research Experience: I joined the services of Indian Council of Medical Research in 1976 as an Assistant Research Officer. I am engaged in medical research since then. The field of research was Immunology and the Initial work was in the field of Filariasis Immunology and Tuberculosis Immunology. Considering the importance of research in HIV and AIDS I was transferred to the National AIDS Research Institute and given the responsibility of establishing Serology and Immunology laboratories in the new premises of the Institute. I have also initiated a programme of Immunological studies. Tuberculosis Research Center, Madras Asst Research Officer (March 1976 to October 1980) Research Officer (October 1980 to July 1983) Senior Research Officer (July 1983 to June 1990) Assistant Director (July 1990 to May 1993) National AIDS Research Institute, Pune Assistant Director (June June 1995) Deputy Director (June 1995 to October 1998) Officer in Charge (October 1998 to March 2006) Director ( March 2006 to till date) Awards & Honors: 1. Recipient of the Certificate of Merit and the recipient of National Science Talent Scholarship, From year 1969 to 1975 Attended five summer schools of one month duration each, between 1969 and Fogarty Fellowship: July 1983-August 1984 at Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, U.S.A. July 1994-May 1995 at The Division of Infectious Diseases, Johns Hopkins University, Baltimore, U.S.A. 3. WHO Fellowship: to strengthen Human Resource development in thrust areas of Medical Research under ICMR relevant to India April 1990-July 1990 at Department of Medicine, Case Total Publications: 106 Ph.D. Fellows: 4 List of Publications: 1. Karikalan Nagarajan, Sheela Godbole, Lakshmi Ramakrishnan, Mandar K. Mainkar, Sowmya Ramesh, Deepika Ganju and Ramesh S Paranjape.Self-Report of STI Symptoms, Inconsistent Condom use and Condom Nonuse are Poor Predictors of STI Prevalence among Men who have Sex with Men. J AIDS Clin Res 2013; 4: Michael Pickles, Marie-Claude Boily, Peter Vickerman, Catherine M Lowndes, Stephen Moses, James F Blanchard, Kathleen N Deering, Janet Bradley, Banadakoppa M Ramesh, Reynold Washington, Rajatashuvra Adhikary, Mandar Mainkar, Ramesh S Paranjape, Michel Alary.Assessment of the population-level effectiveness of the Avahan HIV-prevention programme in South India: a preplanned, causal-pathway-based modelling

3 analysis.lancet Global Health Nov 2013; 1(5): e http://dx.doi.org/ /s x (13) Devidas N Chaturbhuj, Srikanth P Tripathy, Ramesh S Paranjape and JaiP Narain. HIV Drug Resistance in Asia: An Emerging Problem?In Three Decades of HIV / AIDS in Asia. Edited by J P Narain. Published by Sage Publications 2012, pp Nita Mawar, Ramesh S Paranjape and Mohamed Ejazuddin Khan. Social and behavioural research: tool for intensifying fight against AIDS in India. Eastern Journal of Medicine 16 (2011) Thilakavathi Subramanian, Lakshmi Ramakrishnan, Ramesh S. Paranjape. Integrated behavioral and biological assessment: methodological issues in social and behavioral research. Eastern Journal of Medicine 16 (2011) Nita Mawar, Rajani Bagul, Suvarna Sane, Tuman Katendra, Srikanth Prasad Tripathy, Ramesh Shivram Paranjape. Lessons learnt from ongoing counseling during follow-up visits by men and women attending a VCTC Eastern Journal of Medicine 16 (2011) Sushama Jadhav, Srikanth Tripathy, Smita Kulkarni, Kalpana Agnihotri, Arun Risbud, Ramesh Paranjape, Molecular Phylogenetics of nearly full length HIV-2 envelope gene sequences from West India. AIDS Research & Human Retroviruses 24 (2009) 8. Banadakoppa M. Ramesh, Stephen Moses, Reynold Washington, Shajy Isac, Bidhubhushan Mohapatra, Sangameshwar B. Mahagaonkar, Rajatashuvra Adhikary, Ginnela N.V. Brahmam, Ramesh S. Paranjape, Thilakavathi Subramanian and James F. Blanchard, Determinants of HIV prevalence among female sex workers in four south Indian states: analysis of cross-sectional surveys in twenty-three districts for the IBBA Study Team, AIDS 2008, 22 (suppl 5):S35 S Tobi Saidel, Rajatashuvra Adhikary, Mandar Mainkar, Jayesh Dale, Virginia Loo, Motiur Rahman, Banadakoppa M. Ramesh and Ramesh S. Paranjape Banadakoppa M. Ramesh, Stephen Moses, Reynold Washington, Shajy Isac, Bidhubhushan Mohapatra,Sangameshwar B. Mahagaonkar, Rajatashuvra Adhikary, Ginnela N.V. Brahmam, Ramesh S. Paranjape, Thilakavathi Subramanian and James F. Blanchard, Baseline integrated behavioural and biological assessment among most at-risk populations in six high-prevalence states of India: design and implementation challenges for the IBBA Study Team, AIDS 2008, 22 (suppl 5):S17 S Ginnela N.V. Brahmam, Venkaiah Kodavalla, Hemalatha Rajkumar, Hari Kumar Rachakulla, Srinivasan Kallam, Shiva Prakash Myakala, Ramesh S. Paranjape, Mohan D. Gupte, Lakshmi Ramakrishnan, Anjalee Kohlid and Banadakoppa M. Ramesh, Sexual practices, HIV and sexually transmitted infections among self-identified men who have sex with men in four high HIV prevalence states of India for the IBBA Study Team, AIDS 2008, 22 (suppl 5):S45 S Arvind Pandey, Sudhir Kumar Benara, Nandini Roy, Damodar Sahu, Mariamma Thomas, Dhirendra Kumar Joshi, Utpal Sengupta, Ramesh S. Paranjape, Aparajita Bhalla and Ajay Prakash, Risk behaviour, sexually transmitted infections and HIV among long-distance truck drivers: a cross-sectional survey along national highways in India for the IBBA Study Team, AIDS 2008, 22 (suppl 5):S81 S90.

4 12. Thilakavathi Subramanian, Mohan D. Gupte, Ramesh S. Paranjape, Ginnela N.V. Brahmam, Lakshmi Ramakrishnan, Rajatashuvra Adhikary, Boopathi Kangusamy, Beena E. Thomas, Srinivasan Kallam and C.P.K. Girish, HIV, sexually transmitted infections and sexual behaviour of male clients of female sex workers in Andhra Pradesh, Tamil Nadu and Maharashtra, India: results of a cross-sectional survey for the IBBA Study Team, AIDS 2008, 22 (suppl 5):S69 S Jagadish Mahanta, Gajendra Kumar Medhi, Ramesh S. Paranjape, Nandan Roy, Anjalee Kohli, Brogen Akoijam S, Bernice Dzuvichu, Hiranya Kumar Das, Prabuddhagopal Goswami, Gay Thongamba, Injecting and sexual risk behaviours, sexually transmitted infections and HIV prevalence in injecting drug users in three states in India.for the IBBA study team, AIDS 2008, 22 (suppl 5):S59 S Smita Kulkarni, Srikanth Tripathy, Raman Gangakhedkar, Sushama Jadhav, Kalpana Agnihotri, Suvarna Sane, Robert Bollinger and Ramesh Paranjape. Neutralizing antibody responses in recent seroconverters with HIV-1 subtype C infections in India. AIDS Research & Human Retroviruses, 24: (2008). 15. Samir Lakhashe, Srikanth Tripathy, Ramesh Paranjape and Jayanta Bhattacharya; Evidence of a Novel B/C Recombinant Exhibiting Unique Breakpoints of Nearly Full-Length HIV-1 Genome in North Eastern India AIDS Research and Human Retroviruses (Feb 2008) 24: 16. Samir Lakhashe, Srikanth Tripathy, Ramesh Paranjape and Jayanta Bhattacharya; Characterization of B/C Recombinants of Near Full-Length HIV Type 1 from Northeastern India with Mosaics Identical to ARE195FL But with a Different Ancestral Origin.AIDS Research and Human Retroviruses (Jan 2008) 24: Samir K. Lakhashe, Madhuri R. Thakar, K. E. Bharucha and Ramesh S. Paranjape; Quantitation of HLA Proteins Incorporated by Human Immunodeficiency Virus Type 1 and Assessment of Neutralizing Activity of Anti-HLA Antibodies Journal of Virology (Jan 2008) 82: Samir Lakhashe, Madhuri Thakar, Sheela Godbole, Srikanth Tripathy and Ramesh Paranjape. HIV Infection in India : Epidemiology, molecular epidemiology and pathogenesis. Journal of Biosciences Nov 2008; 33 (4) : Ramesh Paranjape, Meera Singh and Samir Lakhashe. Fact File on HIV Vaccine In Monograph of Adult Vaccines (In Press) 20. Mahima Lall, R M Gupta, Sourav Sen, Ketoki Kapila, S P Tripathy and R S Paranjape. Profile of Primary Resistance in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Treatment-Naive Individuals from Western India. AIDS Research and Human retroviruses July 2008; 24 (7): Sanjay Mehendale, Jan van Lunzen, Nathan Clumeck, Jurgen Rockstroh, Eva Vets, Philip R. Johnson, Pervin Anklesaria, Burc Barin, Mark Boaz, Sonali Kochhar, Jennifer Lehrman, Claudia Schmidt, Mathieu Peeters, Carolynne Schwarze-Zander, Kabeya Kabamba, Tobias Glaunsinger, Seema Sahay, Madhuri Thakar, Ramesh Paranjape, Jill Gilmour, Jean-Louis Excler, Patricia Fast, Alison E. Heald. A Phase 1 Study to Evaluate the Safety and Immunogenicity of a Recombinant HIV Type 1 Subtype C Adeno-Associated Virus Vaccine AIDS Research and Human Retroviruses. June 2008:

5 22. Nita Mawar, Pyare L. Joshi, Seema Sahay, Rajani D Bagul, & Ramesh S Paranjape, Concerns and experiences of women participating in a short-term AZT intervention feasibility study for prevention of HIV transmission from mother-to-child Culture, Health & Sexuality, March-April 2007; 9(2): SM Mehendale, MV Ghate, B Kishore Kumar, S Sahay, TR Gamble, SV Godbole, MR Thakar, SS Kulkarni, A Gupta, RR Gangakhedkar, AD Divekar, AR Risbud, RS Paranjape, RC Bollinger. Low HIV-1 incidence among married serodiscordant couples in Pune, India. Journal of Acquired Immune Deficiency Syndromes 2006; 41: Sourav Sen, S.P. Tripathy, V.M. Chimanpure, A.A. Patil, R. D. Bagul, and R.S. Paranjape. Human Immunodeficiency Virus Type 1 drug resistance mutations in peripheral blood mononuclear cell proviral DNA among anti-retroviral Treatment Naïve and Treatment Experienced patients from Pune, India. AIDS Research and Human Retroviruses, 2007;23(4): Swarali N. Kurle, R.R. Gangakhedkar, S. Sen, S.S. Hayatnagarkar, S.P. Tripathy and R.S. Paranjape Emergence of NNRTI drug resistance mutations after single-dose Nevirapine exposure in HIV Type 1 subtype C infected infants AIDS Research and Human Retroviruses 2007;23(5): Lakhashe SK, Kulkarni SS, Thakar MR, Ghate MV, Paranjape RS. Extensive cross-reactive neutralizing antibody response in Indian patients with limited genetic diversity of HIV-1. Virology Mar ; 359(2): Milka A. Rodriguez, Cheng Li Shen, Deena Ratner, R.S. Paranjape, S.S. Kulkarni, Ramdas Chatterjee, and Phalguni Gupta. Genetic and Functional Characterization of the LTR of HIV-1 Subtypes A and C Circulating in India. AIDS Research and Human Retroviruses Nov 2007; 23 (11): Ramesh Paranjape. In: Research Issues in HIV/AIDS. Edited by D Raghunath and C Durga Tata McGraw Hill, New Delhi 2007, pages Riedel D, Ghate M, Nene M, Paranjape R, Mehendale S, Bollinger R, Sacktor N, McArthur J, Nath A. Screening for human immunodeficiency virus (HIV) dementia in an HIV clade C- infected population in India. J Neurovirol Feb;12 (1): Gupte MD, Mehendale SM, Pandav CS, Paranjape RS, Kumar MS. HIV-1 prevalence in young adults in south India. Lancet Jul 8;368 (9530): Sen S, Tripathy SP, Paranjape RS; Antiretroviral Drug Resistance Testing Journal of Postgraduate Medicine 2006; 52 (3): Madhuri R Thakar, B Kishore Kumar, Bharati A Mahajan, Sanjay M Mehendale and Ramesh S Paranjape Comparison of capillary based microflurometric assay for CD4+ T cell count estimation with dual platform Flow Cytometry.AIDS Research and Therapy 2006; 3: Agnihotri KD, Tripathy SP, Jere AP, Kale SM, Paranjape RS. Molecular analysis of gp41 sequences of HIV type 1 subtype C from India. Journal of Acquired Immune Deficiency Syndromes Mar 2006; 41: S Arole, R Premkumar, A Arole, S Mehendale, A Risbud, R Paranjape. Prevalence of HIV infection in pregnant women in remote rural areas of Maharashtra State, India. (Tropical Director, April, 2005; )

6 35. Rewa M. Kohli, Suvarna S. sane, Ramesh S. Paranjape, Sanjay M. Mehendale. Coping strategies adopted by the HIV positive individuals in Pune Quality of Life Research 2005; 14: Smita N. Joshi, V Gopalkrishna, B.Kishorkumar, Soma Dutta, Pratima Nyaynirgune, Madhuri Thakar, Srikanth Tripathy, Sanjay Mehendale and Ramesh Paranjape. Cervical squamous Intra-Epithelial changes and Human Papillomavirus infection in women infected with Human Immunodeficiency Virus in Pune India. J Med Virol, 2005;76: Manocha M, Pal PC, Chitralekha KT, Thomas BE, Tripathi V, Gupta SD, Paranjape R, Kulkarni S, Rao DN Enhanced mucosal and systemic immune response with intranasal immunization of mice with HIV peptides entrapped in PLG microparticles in combination with Ulex Europaeus-I lectin as M cell target (Vaccine.2005; 23: ) 38. Madhuri R. Thakar, Leena S. Bhonge, Samir K. Lakhashe, U. Shankarkumar, Suvarna S. Sane, Smita S. Kulkarni, Bharati A. Mahajan and Ramesh S. Paranjape. HIV-1 C infected Indian patients recognize T cell epitopes from conserved immunodominant region of HIV-1 Gag and Nef. (Journal of Infectious diseases, 2005, 192:749) 39. Smita S. Kulkarni, Tripathy S, Agnihotri K, Jatkar N, Jadhav S, Winston U, Dhande K, Tondare P, Gangakhedkar R and Paranjape RS. Indian primary HIV-2 isolates and relationship between V3 genotype, biological phenotype and coreceptor usage. (Virology 2005; 337: 68-7) 40. Rewa M. Kohli, S. sane, K. Kumar, R.S. Paranjape and S.M. Mehendale. Modification of Medical Outcome Study (MOS) Instrument for quality of life assessment & its validation in HIV infected persons in India.Indian J Med Res 2005;122: Ramesh S. Paranjape, Immunopathogenesis of HIV Infection Indian J Med Res April 2005; 121: Srikanth P. Tripathy, Smita S. Kulkarni, Sushama D. Jadhav, Kalpana D. Agnihotri, Abhay J. Jere, Swarali N. Kurle, Sujit K. Bhattacharya, Khomdon Singh, Sriram P. Tripathy, Ramesh S. Paranjape. Subtype B and Subtype C HIV Type 1 Recombinants in the Northeastern State of Manipur, India. AIDS Research and Human Retroviruses, February 2005, Vol. 21, No. 2: Pages Smita Kulkarni and Ramesh Paranjape, Edited By C.P. Puri and N.K.Ganguly, Publ. Role of Non-Human Primates in HIV /AIDS Research in National Center for Primate Breeding and Research: Vision, Challenges and Opportunities National Institute for Research In Reproductive Health, Parel, Mumbai Abhijit M. Bal, Samir K. Lakhashe, Madhuri R. Thakar, Srikanth P. Tripathy and Ramesh S. Paranjape. Dysregulation of pro-inflammatory and regulatory cytokines in HIV infected persons with active tuberculosis. Cytokine 2005, 30: Eshleman SH, Hudelson S, Gupta A, Bollinger R, Divekar AD, Gangakhedkar RR, Kulkarni SS, Thakar MR, Paranjape RS, and Tripathy S. Limited evolution in the HIV-1 pol region among acute seroconverters in Pune,India. AIDS Res Human Retroviruses. 2005;21(1) Radhika Brahme, Seema Sahay, Rewa Malhotra Kohli, Anand Divekar, Raman Gangakhedkar, Aparna Parkhe, Mahesh Kharat, Arun Risbud, Robert Bollinger, Sanjay Mehendale, Ramesh

7 Paranjape. High risk behaviour of men attending STD clinic in Pune India AIDS Care 2005;17(3): Smita Kulkarni & Ramesh Paranjape Role of Nonhuman Primates in HIV/AIDS Research. NIRH 2005 : Rewa M Kohli, Suvarna Sane, Kishore Kumar, Ramesh S Paranjape & Sanjay Mehendale. Assessment of quality of life among HIV infected persons in Pune, India. Quality of Life Research Aug 2005; 14, Rachana Kairon, Sheela Godbole, Sangeeta Kulkarni, Manisha Ghate, Suvarna Sane, A. Shrotri, Kapila. Barucha, Sanjay Mehendale, Arun Risbud, and Ramesh Paranjpe. Fluconazole resistant non-albicans vaginal yeast in HIV seropositive women with vaginal discharge in Pune, India. (International Journal of Infectious Diseases, 2004; 8: 251-2) 50. S. Sahay, Sanjay Mehendale, Suvarna Sane, Radhika Brahme, Amishah Brown, Karen Charron, Chris Beyrer, Robert Bollinger, Ramesh Paranjape. Correlates of HIV Vaccine Trial Participation: an Indian Perspective Vaccine 2004; 23(11) pp Abhay Jere, Ahmad piroozmand, Srikanth Tripathy, Ramesh Paranjape, Akiko Sakuria, Mikako Fujita and Akio Adachi. Generation and Characterization of HIV-1clones chimeric for subtype B and C Nef International Journal of Molecular Medicine, 2004; 14: Saxena R.K., V. Chaudhary, I. Nath, S. N. Das, R. S. Paranjape, G. Babu, A. Ramalingam, D. Mohanty, H. Vora, M.Thomas, Q.B. Saxena, N.K. Ganguly Normal ranges of some select lymphocyte subpopulations in peripheral blood of normal healthy Indians: Results of a task force study. Current Science 2004;86: Kurle Swarali, Tripathy Srikanth*, Jadhav Sushama, Agnihotri Kalpana and Paranjape Ramesh. Full-length gag sequences of HIV-1 subtype C recent seroconverters from Pune, India. AIDS Res Human Retroviruses 2004; 20(10): Agnihotri Kalpana, Tripathy Srikanth, Jere Abhay, Jadhav Sushama, Kurle Swarali and Paranjape Ramesh. gp120 sequences from HIV -1 subtype C early seroconverters in India. AIDS Research and Human Retroviruses, 2004;20: Abhay Jere, Srikanth Tripathy, Kalpana Agnihotri, Sushma Jadhav, Ramesh Paranjape. Genetic analysis of Indian HIV-1 nef: subtyping, variability and implications. Microbes and Infection 2004;6: Rewa M Kohli, Ramesh S Paranjape, Sanjay M Mehendale, Quality of Life of People Attending the HIV Reference Clinic in Pune, India. Quality of Life Research, 2003; 12,7: Shepherd ME, Gangakhedkar RR, Sahay S, Reynolds SR, Ghate MV, Risbud AR, Paranjape RS, Bollinger RC, Mehendale SM. Incident HIV infection among men attending STD clinics in Pune India: Pathways to disparity and interventions to enhance equity. J Health Population and Nutrition Sep; 21(3): Mridula A. Phadke, B.Gadgil, K.E. Bharucha, A.N. Shrotri, J. Sastry, N.A. Gupte, R. Brookmeyer, R.S. Paranjape, P.M. Bulakh, H. Pisal, N. Suryavanshi, A. Shankar, L.Propper, P.L. Joshi and Robert Bollinger. High post-partum hospitalization rate in replacement fed infants born to HIV infected mothers in India. J Nutr 2003;133:

8 59. Umapathy Shankarkumar, Madhuri Thakar, Sanjay Mehendale, Ramesh Paranjape, Dipika Mohanty. Association of HLA B*3520, B*1801, and Cw* 1507 with HIV-1 infection in Maharashtra, India. Journal of Acquired Immunodeficiency Syndrome, 2003; 34: Arun R. Risbud, Mycal Pareira, S. M. Mehendale, R.R. Gangakhedkar, M.V. Ghate, S. N. Joshi, S. P. Tripathy, R.C. Bollinger and R.S. Paranjape. Lack of evidence for sexual transmission of hepatitis C virus in patients attending STD clinics in Pune. Sex Transm Infect 2003;79: Steven J. Reynolds, A.R. Risbud, M.E. Shephard, J.M. Zenilman, R.S. Brookmeyer, R.S. Paranjape, A.D. Divekar, R.R. Gangakhedjkar, M.V. Ghate, R.C. Bollinger and S.M. Mehendale. Recent Herpes Simplex Virus Type 2 Infection and Risk of Human Immunodeficiecy Virus Type I Acquisition in India. J Infect Dis 2003;187: Monika Manocha, Chitralekha K.T., Thakar M,. Paranjape R. S., Rao D.N. Comparing modified and plain peptide linked enzyme immunosorbent assay (ELISA) for detection of human immunodeficiency virus type-1 (HIV-1) and type-2 (HIV-2) antibodies. Immunology Letters, 2003;85: Bhore AV, Sastry J,Patke D,Gupte N, Lele S, Karmarkar A, Bharucha KE, Shrotri A, Pisal H, Suryavanshi N, Tripathy S, Risbud AR, Paranjape RS, Shankar AV, Kshirsagar A, Phadke MA, Joshi PL, Brookmeyer RS and Bollinger RC. Sensitivity and Specificity of Rapid HIV Testing of Pregnant Women. International Journal of STD & AIDS 2003;14: N. Mawar and R.S. Paranjape. Live and Let live.acceptance of People living with HIV/AIDS in an Era where Stigma and Discrimination persist ICMR Bulletin2002;32: Sanjay M. Mehendale, R.C. Bollinger, S.K. Kulkarni, R. Stallings, R.S. Brookmeyer, S.V. Kulkarni, A. D. Divekar, R.R. Gangakhedkar, S.N. Joshi, A.R. Risbud, M.R. Thakar, B.A. Mahajan, V.A. kale, M.V. Ghate, D.A. Gadkari, T. C. Quinn, R. S. Paranjape. Rapid progression in Human Immunodeficiency Virus Type! infected seroconverters in India. AIDS Research and Human Retroviruses, 2002;18: M.R. Thakar, D. Patke, S.K. lakashe, L. Bhonge, S.V. Kulkarni, S.P. Tripathy, N. Gupte, R. Brookmeyer, T.C. Quinn, R.S. Paranjape, R.C. Bollinger. Consistent subtype-specific Anti- HIV 1 T lymphocyte Responses in Indian Subjects Recently infected with HIV-1. AIDS Research and Human Retroviruses, 2002;18: S. Tripathy, DR Joshi, SM Mehendale, P.Menon, AN Joshi, SV Ghorpade, U Patil and RS Paranjape Sentinel surveillance for HIV Infectionin Tuberculosis Patients in India Indian J Tuberculosis 2002;49: Risbud AR, Mehendale SM, Basu S, Kulkarni SS, Walimbe A, Arankalle V, Gangakhedkar RR, Divekar AD, Bollinger RC, Gadkari DA and Paranjape RS. Prevalence and Incidence of Hepatitis B virus infection in STD clinic antendees in Pune, India. Sexually Transmitted Infections 2002; 78: S.M. Mehendale, M.E. Shepherd, R.S. Brookmeyer, R.D. Semba, R.S. Paranjape A.D. Divekar, R.R. Gangakhedkar, S. Joshi, A.R. Risbud, D.A. Gadkari and R.C. Bollinger. Low Carotinoid Concentration and the Risk of HIV Seroconversion in Pune, India JAIDS 2001;26:

9 70. M.V. Ghate, S.M. Mehendale, B.A. Mahajan, R.Yadav, R.G. Brahme, A.D. Divekar & R. S. Paranjape. Relationship between reported clinical conditions and CD4 lymphocyte counts in HIV infected subjects in Pune, India. National Medical Journal of India. 2000;13: D. Cecilia, S.S. Kulkarni, S.P. Tripathy, R.R. Gangakhedkar, R.S. Paranjape and D.A. Gadkari. Absence of coreceptor switch with Disease progression in Human Immunodeficiency Virus infection in India. Virology 2000;271: Quinn TC, Brookmeyer R, Kline R, Shepherd M, Paranjape R, Mehendale S,Gadkari DA, Bollinger R.C. Feasibility of Pooling Sera for HIV-1 Viral RNA to Diagnose Acute, Primary HIV-1 Infection and Estimate HIV-1 Incidence.AIDS 2000, 14: Tripathy S, Menon P, Joshi DR, Patil U, Gadkari DA and Paranjape RS. Lymphocyte subpopulations in HIV seropositive and HIV seronegative tuberculosis patients in Pune, India Ind J Med Res 2000;111: Thakar M.R., Ghate M.V. and Paranjape R.S.Collection of Blood on Filter Paper; Stability and validation Study for HIV Serology.Indian Journal of Community Medicine. 2000;XXV: Ghate M.V. and Paranjape R.S., Chemoprophylaxix after Occupational exposure to HIV AIDS Research and Review1999;2: Vinay Kulkarni, Immunology of HIV in HIV/AIDS: Diagnosis and management Physician s Handbook, Ed. Publ. Prayas, Pune Direct evidence of HIV infection in HIV Testing Manual: Laboratory Diagnosis, Biosafety and Quality Control. Publ. National AIDS Control Organization, Ministry of Health and Family Welfare, Government of India. 78. Senthil Kumar K.S., Alamelu Raja, Uma Devi K.R. and Paranjape R.S.Production and Characterization of monoclonal antibodies to Mycobacterium tuberculosis Ind J Med Res 2000;112: Kunte A, Misra V, Paranjape R, Mansukhani N, Padbidri V, Gojrani S, Kakrani V, Thakar M and Mehendale S. HIV seroprevalence and awareness about AIDS among pregnant women in rural areas of Pune District of Maharashtra. Ind J Med Res 1999; 110: Kulkarni Smita S, Tripathy S, Paranjape RS, Mani NS, Joshi DR, Patil U and Gadkari DA. Isolation and preliminary characterization of two HIV-2 strains from India. Ind J Med Res 1999;109: Paranjape R.S.HIV vaccine development: An Overview AIDS Research and Reviews 1999; 2: Lole Kavita S, Bollinger RC, Paranjape RS, Gadkari D, Kulkarni SS, Novac NG, Ingersoll R, Sheppard H and Ray SC. Full Length Human Immunodeficiency Virus Type 1 Genomes from Subtype C-Infected Seroconverters in India, with Evidence of Intersubtype Recombination. J Virol 1999; Ramesh S. Paranjape, Deepak A. Gadkari, Michel Lubaki, Thoma C. Quinn and Robert C. Bollinger. Cross-reactive HIV-1-specific CTL in Recent Seroconverters from Pune,India. Indian J Med Res 1998; 108:35-41.

10 84. Paranjape R.S., Tripathy S.P., Menon P.A., Mehendale S.M., Khatavkar, P, Joshi P.D., PatilU, Gadkari D.A. and Rodrigues J.J. Increasing trend of HIV seroprevalence among Pulmonary Tuberculosis Patients in Pune, India. Indian J Med Res 1997;106: Robert C. Bollinger, Ronald S. Brookmeyer, Sanjay M. Mehendale, Ramesh S. Paranjape, Mary E. Shepherd, Deepak A. Gadkari and Thomas C. Quinn. Risk factors and clinical presentation of acute primary human immunodeficiency virus infection in India. JAMA 1997;278: R.S. Paranjape.Immunologic Responses in HIV Infection Proceedings of National Conference on HIV/AIDS Medicine, Poona Medical Research Foundation and National AIDS Research Institute, Pune. November 23-24, Ramesh S. Paranjape, S.S.Kulkarni, Sumit Chanda, S.M.Mehendale, S.S.Jawadekar, A.K.Pratinidhi and J.J.Rodrigues. Evaluation of algorithms of anti-hiv antibody tests ( without western blot) on sera from long distance truck drivers. Indian Journal Of Community Medicine;XXII: Mehendale SM, Shepherd ME, Divekar AD, Gangakhedkar RR, Kamble SJ, Menon PA, Yadav R, Risbud AR, Paranjape RS, Gadkari DA, Quinn TC, Bollinger RC and Rodrigues JJ. Evidence for high prevalence and rapid transmission of HIV among individuals attending STD clinics in Pune, India. IJMR 1996;104: Bollinger R., T. Quinn, J. Rodrigues, S. Mehendale, R. Brookmeyer, A. Risbud, R. Gangakhedkar, A. Divekar, M. Shepherd, R. Paranjape. HIV sero-incidence and risk factors for seroconversion in patients attending STD clinics in Pune, India. AIDS Research and Human Retroviruses, 1995:11; S173. Abstract No. 258B. 90. Sanjay M. Mehendale, J.J.Rodrigues, R.S.Brookmeyer, R.R.Gangakhedkar, A.D.Divekar, M.R.Gokhale, A.R.Risbud, R.S.Paranjape, M.E.Shepherd, A.E.Rompalo, R.R.Sule,S.N.Tolat, V.D.Jadhav, T.C.Quinn and R.C.Bollinger. HIV-1 incidence and predictors of seroconversion in patients attending sexually transmitted diseases clinics in India". Journal of Infec Dis 1995;172: JeanetteJ.Rodrigues,S.M.Mehendale,M.E.Shepherd,A.D.divekar,R.R.Gangakhedar, T.C.Quinn, R.S.Paranjape, A.R.Risbud, R.S.Brookmeyer, D.A.Gadkari, M.R.Gokhale, A.M.Rompalo,S.G.Deshpande, M.M.Khaladkar, N.Mawar and R.C.Bollinger(1995). Risk factors for HIV infection in People attending clinics for sexually transmitted diseases in India.British Medical Journal,311, pp Robert S. Wallis, Ramesh Paranjape and Manijeh Phillips(1993). Identification of Two- Dimensional Gel Electrophoresis of a 58 Kilodalton TNF inducing protein of M. Tuberculosis Infection and Immunity 61(2), PP: R. Paranjape (1990). Immunodiagnosis in Tuberculosis Tropical Medicine and Parasitology 41(3): PP Paranjape, R.S., Ravoof, A., Acharyulu, G.S., Krishnamurthy, P.V., Tripathy, S.P., Narayanan, P.R., and Prabhakar, R. (1988). Cell mediated immune response in South Indian pulmonary tuberculosis patients. Indian Journal of Tuberculosis, 35:

11 95. Milford N. Lunde, Ramesh Paranjape, Thomas J. Lawley and Eric A. Ottesen (1987). Filarial antigen in circulating immune complexes from patients with Wuchereria bancrofti filariasis. American Journal of Tropical Medicine and Hygiene, 38(2): Renu B. Lal, Ramesh S. Paranjape, Briles, D. E., Nutman, T.B. Eric A. Ottesen. (1987). Circulating parasite antigen(s) in lymphatic filariasis: Use of monoclonal antibodies to phosphocholine for immunodiagnosis. Journal of Immunology, 138: Narayanan, P.R. and Paranjape, R.S. (1986). Detection of circulating filarial antigen. Annals of the Nat. Aca. Med. Sci., 21: Ramesh S. Paranjape, Acharyulu, G.S., Krishnamurthy, P.V., Padma R. (1986). Cell mediated immunity in children with tuberculous meningitis. Indian Paediatrics, 123: Ramesh S. Paranjape, Rabin Hussain, Thomas B. Nutman, Robert Hamilton and Eric A. Ottesen (1986). Identification of circulating parasite antigen in patients with bancroftian filariasis. Clin. Exp. Immunol. 63: Ramesh S. Paranjape, Kumaraswami, V., Prabhakar, R. and Narayanan, P.R.(1985). Increased serum level of antifilarial IgA antibodies in Patients with Tropical Pulmonary Eosinophilia. Lung India III(1): Ramesh S. Paranjape, Kumaraswami, V., Prabhakar, S. Subramanian and P.R. Narayanan(1985). Anti-filarial IgG antibodies in patients with Bancroftian filariasis and tropical pulmonary eosinophilia. Indian J. Exp. Biology, 23: Paranjape, R.S., R.Hussain, T.Nutman and E.Ottesen (1984). Detection of High Molecular weight circulating parasite antigen in Bancroftian filariasis. Federation Proceedings, 43(6) Abstract No Ottensen, E.A., V.Kumaraswami, Ramesh Paranjape, R.W. Pointdexter and S.P. Tripathy (1981). Naturally occurring blocking antibodies modulate immediate hypersensitivity responses in human filariasis. Journal of Immunology, 127(5): Ramesh Paranjape (1981).Immune response in human filariasis. Ph.D. Thesis submitted to University of Madras Ottesen, E.A., F.A. Neva, R.S. Paranjape, S.P. Tripathy, K.V. Thiruvengadam and M.A. Beaver (1979). Specific allergic sensitization to filarial antigens in tropical eosinophilia syndrome. Lancet, 1: Paranjape, R., A. Sen and A. Das Gupta(1976). An attempt to characterize antigens from adult rat filaria. Aspect.